• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Sus-0139
LMNA

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Prelamin-A/C
Gene Name: LMNA
Ensembl Gene: ENSSSCG00000006496.3
Ensembl Protein: ENSSSCP00000047557.1
Organism: Sus scrofa
Taxa ID: 9823
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Perinucleolar compartment, Stress granule, OthersPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     METPSQRRAT  RSGAQASSTP  LSPTRITRLQ  EKEDLQELND  RLAVYIDRVR  SLETENAGLR  60
61    LRITESEEVV  SREVSGIKSA  YEAELGDARK  TLDSVAKERA  RLQLELSKVR  EEFKELKARN  120
121   TKKEGDLMAA  QARLKDLEAL  LNSKEAALST  ALSEKRTLEG  ELHDLRGQVA  KLEAALGEAK  180
181   KQLQDEMLRR  VDAENRLQTL  KEELDFQKNI  YSEELRETKR  RHETRLVEID  NGKQREFESR  240
241   LADALQELRA  QHEDQVEQYK  KELEKTYSAK  LDNARQSAER  NSNLVGAAHE  ELQQSRIRID  300
301   SLSAQLSQLQ  KQLAAKEAKL  RDLEDSLARE  RDTSRRLLAD  KEREMAEMRA  RMQQQLDEYQ  360
361   ELLDIKLALD  MEIHAYRKLL  EGEEERLRLS  PSPTSQRSRG  RASSHSSQTQ  SGGSVTKKRK  420
421   LESSESRSSF  SQHARTSGRV  AVEEVDEEGK  FVRLRNKSNE  DQSMGNWQIK  RQNGDDPLLT  480
481   YRFPPKFTLK  AGQVVTIWAA  GAGATHSPPA  DLVWKSQNTW  GCGNSLRTAL  INSTGEEVAM  540
541   RKLVRSVTMI  EDDEDEDGDD  LLHHHHGSHG  SSSGDPAEYN  LRSRTVLCGT  CGQPADKASA  600
601   SSSGAQVGGS  ISSGSSASSV  TVTRSYRSVG  GSGGGSFGDN  LVTRSYLLGN  SRPRTQSPQN  660
661   CSIM  664
Nucleotide CDS Sequence (FASTA)
1     ATGGAGACCC  CGTCCCAGCG  GCGCGCCACC  CGCAGCGGGG  CGCAGGCCAG  CTCCACCCCG  60
61    CTGTCGCCCA  CCCGCATCAC  CCGGCTACAG  GAGAAGGAGG  ACCTGCAGGA  GCTCAATGAC  120
121   CGCTTGGCGG  TTTACATCGA  CCGTGTGCGC  TCACTGGAGA  CGGAGAATGC  AGGTCTGCGC  180
181   CTTCGCATCA  CCGAGTCTGA  AGAGGTGGTC  AGTCGCGAGG  TGTCTGGCAT  CAAGTCTGCC  240
241   TACGAGGCCG  AGCTCGGGGA  TGCCCGCAAG  ACCCTCGACT  CGGTGGCCAA  GGAGCGCGCC  300
301   CGCCTGCAGC  TGGAGCTGAG  CAAAGTCCGC  GAGGAGTTCA  AGGAGCTCAA  GGCACGCAAT  360
361   ACCAAGAAGG  AGGGAGACTT  GATGGCCGCC  CAGGCCCGGC  TCAAGGACCT  GGAGGCTCTG  420
421   CTCAACTCCA  AGGAGGCAGC  ACTGAGCACC  GCTCTCAGCG  AGAAGCGCAC  GCTGGAAGGC  480
481   GAGCTGCATG  ACCTGCGAGG  ACAAGTGGCC  AAGCTCGAGG  CAGCCCTGGG  TGAGGCCAAG  540
541   AAACAACTTC  AGGATGAGAT  GCTGCGCCGA  GTGGATGCCG  AGAACAGGCT  GCAGACCCTG  600
601   AAGGAGGAGC  TGGACTTCCA  GAAGAACATT  TACAGCGAGG  AGCTTCGGGA  GACCAAGCGC  660
661   CGCCATGAGA  CGCGGCTGGT  GGAGATTGAT  AATGGGAAGC  AGCGCGAGTT  TGAGAGCCGG  720
721   CTGGCAGATG  CCCTGCAGGA  GCTGCGGGCC  CAGCACGAGG  ACCAGGTGGA  ACAGTACAAG  780
781   AAGGAGCTGG  AGAAGACCTA  TTCTGCCAAG  CTGGATAACG  CCAGGCAGTC  GGCCGAGAGG  840
841   AACAGCAACC  TGGTGGGGGC  CGCCCACGAG  GAGCTGCAGC  AGTCCCGCAT  CCGCATCGAC  900
901   AGCCTCTCGG  CCCAGCTCAG  CCAGCTCCAG  AAGCAGCTGG  CAGCCAAGGA  GGCCAAGCTG  960
961   CGGGACCTGG  AGGACTCGCT  GGCCCGTGAG  CGTGACACCA  GCCGGCGGCT  GCTGGCCGAC  1020
1021  AAGGAGCGGG  AGATGGCGGA  GATGCGGGCA  AGGATGCAGC  AGCAGCTGGA  CGAGTACCAG  1080
1081  GAGCTGCTGG  ACATCAAGCT  GGCCCTGGAC  ATGGAGATCC  ACGCCTACCG  CAAGCTCCTG  1140
1141  GAGGGCGAGG  AGGAGAGGCT  ACGCCTGTCC  CCCAGCCCGA  CCTCGCAGCG  CAGCCGCGGC  1200
1201  CGGGCCTCTT  CCCACTCGTC  CCAGACGCAG  AGTGGGGGCA  GCGTCACCAA  AAAGCGCAAG  1260
1261  CTGGAGTCCA  GTGAGAGCCG  CAGCAGCTTC  TCCCAGCACG  CTCGCACCAG  CGGCCGTGTG  1320
1321  GCCGTGGAGG  AGGTGGACGA  GGAGGGCAAG  TTCGTGCGCC  TGCGCAACAA  GTCCAATGAG  1380
1381  GACCAGTCCA  TGGGCAACTG  GCAGATCAAG  CGCCAGAATG  GAGATGATCC  CTTGCTGACC  1440
1441  TACCGCTTCC  CTCCAAAGTT  CACTCTGAAG  GCCGGGCAGG  TGGTGACGAT  CTGGGCTGCG  1500
1501  GGAGCGGGGG  CCACCCACAG  CCCCCCAGCC  GACTTGGTGT  GGAAGTCGCA  GAACACCTGG  1560
1561  GGCTGCGGAA  ACAGCCTGCG  CACGGCTCTC  ATCAACTCCA  CTGGGGAAGA  GGTGGCCATG  1620
1621  CGCAAGCTGG  TGCGCTCGGT  GACCATGATT  GAGGACGACG  AGGATGAGGA  TGGAGATGAC  1680
1681  CTGCTCCATC  ACCACCACGG  CTCCCATGGC  AGCAGCTCGG  GGGACCCCGC  CGAGTACAAC  1740
1741  CTGCGCTCAC  GCACCGTGCT  GTGTGGGACC  TGCGGGCAGC  CCGCCGACAA  GGCGTCTGCC  1800
1801  AGCAGCTCGG  GAGCCCAGGT  GGGCGGATCC  ATCTCCTCTG  GCTCCTCCGC  CTCCAGTGTC  1860
1861  ACAGTCACTC  GCAGCTACCG  CAGTGTGGGG  GGCAGTGGGG  GTGGCAGCTT  CGGGGACAAC  1920
1921  CTGGTCACCC  GCTCCTACCT  CCTGGGCAAC  TCTAGACCCC  GAACCCAGAG  CCCCCAGAAC  1980
1981  TGCAGCATCA  TGTAA  1995

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Urm-1891Ursus maritimus99.65e-144 439
LLPS-Gog-0835Gorilla gorilla97.890.0 970
LLPS-Hos-2127Homo sapiens97.890.0 970
LLPS-Poa-0945Pongo abelii97.890.0 970
LLPS-Caj-0451Callithrix jacchus97.740.0 969
LLPS-Maf-2362Macaca fascicularis97.740.0 967
LLPS-Chs-0845Chlorocebus sabaeus97.740.0 967
LLPS-Mal-4209Mandrillus leucophaeus97.740.0 967
LLPS-Paa-0476Papio anubis97.740.0 967
LLPS-Tut-0526Tursiops truncatus97.740.0 964
LLPS-Otg-4098Otolemur garnettii97.740.0 943
LLPS-Pap-1073Pan paniscus97.740.0 968
LLPS-Pat-3227Pan troglodytes97.740.0 968
LLPS-Man-0540Macaca nemestrina97.740.0 967
LLPS-Mam-2101Macaca mulatta97.740.0 967
LLPS-Aon-2745Aotus nancymaae97.590.0 964
LLPS-Nol-2323Nomascus leucogenys97.590.0 969
LLPS-Orc-0021Oryctolagus cuniculus97.440.0 962
LLPS-Eqc-0148Equus caballus97.440.0 964
LLPS-Fec-1500Felis catus97.290.0 967
LLPS-Loa-3334Loxodonta africana96.840.0 957
LLPS-Ict-0317Ictidomys tridecemlineatus96.840.0 958
LLPS-Cea-0572Cercocebus atys96.830.0 944
LLPS-Rhb-2430Rhinopithecus bieti96.680.0 944
LLPS-Mup-1413Mustela putorius furo96.240.0 956
LLPS-Caf-2407Canis familiaris96.230.0 936
LLPS-Ran-0455Rattus norvegicus95.350.0 951
LLPS-Dio-1419Dipodomys ordii95.180.0 960
LLPS-Fud-1392Fukomys damarensis95.140.0 670
LLPS-Mum-0508Mus musculus94.740.0 941
LLPS-Myl-1000Myotis lucifugus94.290.0 942
LLPS-Ere-0048Erinaceus europaeus93.250.0 939
LLPS-Bot-0159Bos taurus92.630.0 959
LLPS-Mea-0072Mesocricetus auratus92.620.0 955
LLPS-Mod-1852Monodelphis domestica91.420.0 921
LLPS-Cas-3831Carlito syrichta91.250.0 692
LLPS-Ora-1600Ornithorhynchus anatinus91.236e-154 456
LLPS-Sah-1135Sarcophilus harrisii90.480.0 636
LLPS-Cap-0632Cavia porcellus89.490.0 874
LLPS-Ova-0169Ovis aries86.680.0 824
LLPS-Pes-1166Pelodiscus sinensis79.40.0 837
LLPS-Fia-2333Ficedula albicollis77.330.0 814
LLPS-Anc-1355Anolis carolinensis76.560.0 582
LLPS-Tag-2345Taeniopygia guttata74.910.0 630
LLPS-Lac-0584Latimeria chalumnae72.310.0 682
LLPS-Xet-0820Xenopus tropicalis71.130.0 741
LLPS-Asm-0795Astyanax mexicanus70.20.0 623
LLPS-Dar-0669Danio rerio66.020.0 656
LLPS-Xim-2626Xiphophorus maculatus64.980.0 629
LLPS-Scf-1456Scleropages formosus64.710.0 687
LLPS-Pof-4140Poecilia formosa64.660.0 625
LLPS-Orl-3440Oryzias latipes64.630.0 605
LLPS-Orn-2267Oreochromis niloticus63.90.0 626
LLPS-Scm-1233Scophthalmus maximus63.470.0 623
LLPS-Tar-1961Takifugu rubripes63.360.0 618
LLPS-Gaa-0341Gasterosteus aculeatus63.030.0 613
LLPS-Ten-1233Tetraodon nigroviridis62.130.0 601
LLPS-Icp-0259Ictalurus punctatus60.290.0 648
LLPS-Aim-2140Ailuropoda melanoleuca53.98e-147 446
LLPS-Gaga-0639Gallus gallus53.72e-154 468
LLPS-Anp-2884Anas platyrhynchos52.641e-111 351
LLPS-Leo-2642Lepisosteus oculatus48.22e-133 412
LLPS-Meg-2532Meleagris gallopavo47.695e-112 353
LLPS-Drm-2025Drosophila melanogaster38.221e-82 280
LLPS-Cis-1761Ciona savignyi37.788e-46 174
LLPS-Cii-1519Ciona intestinalis37.379e-45 171
LLPS-Cae-0324Caenorhabditis elegans31.274e-39 155