LLPS-Scp-1337
nup44
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Nucleoporin nup44; Nuclear pore protein nup44 |
| Gene Name: | nup44, SPBC19G7.15 |
| Ensembl Gene: | SPBC19G7.15 |
| Ensembl Protein: | SPBC19G7.15.1 |
| Organism: | Schizosaccharomyces pombe |
| Taxa ID: | 284812 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nuclear pore complex | Predicted from orthologs | (View) |
▼ FUNCTION
| Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | SPBC19G7.15.1 | SPBC19G7.15.1 |
| UniProt | O42963, NUP44_SCHPO, P78918, Q1L840 | |
| GeneBank | D89269, CU329671 | CAA17069.1, BAA13930.1 |
| RefSeq | NM_001021888.2 | NP_595981.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAFSFGQQGS SIKAPSIGST GVFGQSNTTK PTAPFGSGSI FGSTNTNVGA GGPTGSSSAP 60 61 PFGNSIFGKT QQQPTTSFSN TTTNAPQSTV FGQNAASRTG NSNTQPLFSW STVNNPTKPV 120 121 DETNATIPSS LLLSSGISPN ATVSNAQYGP AQPPSVEEQV QKILNAWNLN HPDCAFQRFF 180 181 YNKVPVEQAA LYVKPPNYNQ QKWDEAVANR PSNSVVPVLA VGFPDVQKRI NMQIQQVNTY 240 241 RIRMREIVET LGRLSNKHDL DFSIKLAEAK NRHVRLSERI LRLAIKVHVL RHRGYALKPN 300 301 EEELRKKLDD LTKSLNNPEI FGRLNEIWAR ITLIFEGEKI SEDQRSNLAK GVVDWRKNSD 360 361 QLEVITDVLR DHQVGLSYVV KLMQEDLATL NKQLTEHVPQ SQK 403 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCATTTT CTTTTGGTCA ACAAGGGTCG TCAATAAAGG CACCTTCCAT TGGCTCAACT 60 61 GGCGTTTTTG GCCAGTCGAA TACCACAAAA CCAACTGCAC CTTTCGGTTC TGGATCTATT 120 121 TTTGGGTCCA CAAACACTAA TGTAGGTGCA GGAGGCCCTA CTGGTTCTTC GTCAGCTCCA 180 181 CCGTTTGGAA ATTCAATTTT CGGTAAAACA CAACAACAGC CGACCACTTC TTTCTCCAAT 240 241 ACTACCACCA ATGCCCCACA AAGTACTGTA TTTGGCCAAA ACGCTGCATC AAGAACCGGC 300 301 AACTCAAATA CGCAACCATT ATTTTCGTGG AGTACAGTCA ACAATCCCAC AAAACCAGTA 360 361 GACGAAACCA ATGCTACGAT CCCTAGCAGC TTATTGCTGT CTTCAGGTAT ATCCCCAAAT 420 421 GCGACCGTGA GCAATGCTCA ATATGGCCCT GCTCAACCTC CGTCCGTGGA GGAGCAAGTG 480 481 CAGAAAATCT TGAATGCATG GAATCTCAAC CATCCTGATT GTGCTTTTCA GCGGTTCTTT 540 541 TATAACAAGG TTCCTGTTGA GCAAGCTGCA CTATATGTTA AGCCTCCAAA TTATAACCAA 600 601 CAAAAATGGG ACGAAGCTGT TGCTAATCGA CCAAGCAACA GTGTTGTTCC CGTTTTGGCC 660 661 GTAGGATTCC CCGATGTACA AAAAAGAATT AATATGCAGA TTCAACAAGT GAACACGTAC 720 721 CGTATTCGGA TGCGTGAAAT TGTTGAAACT TTAGGAAGAT TAAGTAACAA ACACGACCTT 780 781 GATTTTAGCA TCAAACTTGC CGAGGCGAAA AATCGTCACG TCCGTCTGTC TGAAAGAATT 840 841 TTACGACTTG CAATTAAAGT ACATGTTTTA CGACATCGTG GTTATGCACT AAAACCTAAT 900 901 GAAGAAGAGC TACGTAAAAA ATTAGATGAT TTAACAAAAT CGCTAAATAA TCCTGAAATT 960 961 TTTGGTCGGC TCAACGAAAT ATGGGCAAGA ATTACTCTTA TTTTTGAAGG AGAAAAGATA 1020 1021 TCTGAAGATC AGCGAAGTAA TTTGGCTAAG GGAGTAGTGG ATTGGCGAAA AAATTCTGAT 1080 1081 CAACTAGAAG TCATTACGGA CGTCTTAAGG GATCATCAAG TTGGTCTTTC ATATGTGGTA 1140 1141 AAACTGATGC AAGAAGATTT AGCGACGTTG AACAAGCAAT TAACTGAGCA CGTTCCTCAA 1200 1201 TCACAAAAAT AG 1212 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Nuclear envelope | |
Cellular Component | Nuclear periphery | |
Cellular Component | Nuclear pore | |
Cellular Component | Nuclear pore central transport channel | |
Cellular Component | Nucleus | |
Molecular Function | Structural constituent of nuclear pore | |
Biological Process | NLS-bearing protein import into nucleus | |
Biological Process | Nuclear pore organization | |
Biological Process | Protein localization to nuclear inner membrane | |
Biological Process | RRNA export from nucleus |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Scc-0353 | Schizosaccharomyces cryophilus | 68.18 | 0.0 | 543 |
| LLPS-Scj-0779 | Schizosaccharomyces japonicus | 53.83 | 4e-140 | 414 |
| LLPS-Yal-0359 | Yarrowia lipolytica | 43.03 | 2e-67 | 229 |
| LLPS-Tum-0513 | Tuber melanosporum | 39.38 | 3e-51 | 185 |
| LLPS-Blg-1454 | Blumeria graminis | 38.59 | 1e-38 | 145 |
| LLPS-Ast-0554 | Aspergillus terreus | 38.38 | 2e-35 | 140 |
| LLPS-Phn-1078 | Phaeosphaeria nodorum | 35.5 | 3e-44 | 164 |
| LLPS-Abg-0531 | Absidia glauca | 35.02 | 4e-41 | 157 |
| LLPS-Mao-0850 | Magnaporthe oryzae | 34.85 | 6e-37 | 142 |
| LLPS-Kop-0315 | Komagataella pastoris | 34.82 | 2e-42 | 161 |
| LLPS-Scs-0536 | Sclerotinia sclerotiorum | 34.47 | 8e-41 | 155 |
| LLPS-Nef-1653 | Neosartorya fischeri | 33.6 | 3e-37 | 145 |
| LLPS-Asfu-1112 | Aspergillus fumigatus | 33.6 | 6e-37 | 144 |
| LLPS-Dos-1505 | Dothistroma septosporum | 33.18 | 8e-29 | 121 |
| LLPS-Asc-0759 | Aspergillus clavatus | 33.05 | 4e-35 | 140 |
| LLPS-Asn-1293 | Aspergillus nidulans | 32.79 | 2e-34 | 137 |
| LLPS-Zyt-1254 | Zymoseptoria tritici | 32.52 | 2e-30 | 124 |
| LLPS-Nec-1526 | Neurospora crassa | 32.52 | 6e-41 | 153 |
| LLPS-Gag-1186 | Gaeumannomyces graminis | 32.39 | 4e-34 | 135 |
| LLPS-Asni-1481 | Aspergillus niger | 32.24 | 8e-37 | 144 |
| LLPS-Pat-4062 | Pan troglodytes | 32.09 | 1e-11 | 70.5 |
| LLPS-Trr-0541 | Trichoderma reesei | 31.94 | 1e-32 | 130 |
| LLPS-Pytr-0932 | Pyrenophora triticirepentis | 31.19 | 1e-48 | 176 |
| LLPS-Bot-0536 | Bos taurus | 30.46 | 5e-20 | 95.9 |
| LLPS-Ova-0216 | Ovis aries | 30.46 | 6e-20 | 95.5 |
| LLPS-Myl-3735 | Myotis lucifugus | 30.46 | 4e-20 | 95.9 |
| LLPS-Chc-0568 | Chondrus crispus | 30.3 | 2e-13 | 73.9 |
| LLPS-Loa-1027 | Loxodonta africana | 29.95 | 4e-19 | 93.2 |
| LLPS-Man-0092 | Macaca nemestrina | 29.95 | 6e-19 | 92.8 |
| LLPS-Fec-2241 | Felis catus | 29.95 | 1e-19 | 95.1 |
| LLPS-Lac-1847 | Latimeria chalumnae | 29.95 | 4e-18 | 90.1 |
| LLPS-Hos-3456 | Homo sapiens | 29.95 | 6e-19 | 92.8 |
| LLPS-Pap-0152 | Pan paniscus | 29.95 | 6e-19 | 92.8 |
| LLPS-Pof-1061 | Poecilia formosa | 29.95 | 3e-18 | 90.5 |
| LLPS-Rhb-0151 | Rhinopithecus bieti | 29.95 | 6e-19 | 92.4 |
| LLPS-Orc-0233 | Oryctolagus cuniculus | 29.95 | 8e-19 | 92.0 |
| LLPS-Mam-2441 | Macaca mulatta | 29.95 | 2e-19 | 94.0 |
| LLPS-Cap-1061 | Cavia porcellus | 29.95 | 4e-19 | 92.8 |
| LLPS-Eqc-1574 | Equus caballus | 29.95 | 2e-19 | 94.0 |
| LLPS-Caf-0822 | Canis familiaris | 29.95 | 1e-19 | 94.7 |
| LLPS-Poa-0080 | Pongo abelii | 29.95 | 2e-19 | 94.0 |
| LLPS-Nol-1081 | Nomascus leucogenys | 29.95 | 7e-19 | 92.4 |
| LLPS-Ict-3498 | Ictidomys tridecemlineatus | 29.95 | 5e-19 | 92.8 |
| LLPS-Gaga-1384 | Gallus gallus | 29.95 | 4e-19 | 93.2 |
| LLPS-Sus-2483 | Sus scrofa | 29.95 | 2e-19 | 94.0 |
| LLPS-Aon-1907 | Aotus nancymaae | 29.95 | 7e-19 | 92.4 |
| LLPS-Sah-3116 | Sarcophilus harrisii | 29.95 | 1e-19 | 94.4 |
| LLPS-Cea-2255 | Cercocebus atys | 29.95 | 6e-19 | 92.8 |
| LLPS-Chs-0822 | Chlorocebus sabaeus | 29.95 | 6e-19 | 92.8 |
| LLPS-Maf-4212 | Macaca fascicularis | 29.95 | 6e-19 | 92.8 |
| LLPS-Mea-1342 | Mesocricetus auratus | 29.95 | 3e-19 | 93.6 |
| LLPS-Caj-0248 | Callithrix jacchus | 29.95 | 2e-19 | 94.4 |
| LLPS-Fud-3427 | Fukomys damarensis | 29.95 | 3e-19 | 93.2 |
| LLPS-Gog-0489 | Gorilla gorilla | 29.95 | 6e-19 | 92.8 |
| LLPS-Dio-2653 | Dipodomys ordii | 29.95 | 3e-19 | 93.2 |
| LLPS-Xim-1850 | Xiphophorus maculatus | 29.95 | 9e-19 | 92.4 |
| LLPS-Aim-1506 | Ailuropoda melanoleuca | 29.95 | 6e-19 | 92.4 |
| LLPS-Mup-1616 | Mustela putorius furo | 29.95 | 2e-19 | 94.4 |
| LLPS-Paa-1846 | Papio anubis | 29.95 | 6e-19 | 92.8 |
| LLPS-Mal-1617 | Mandrillus leucophaeus | 29.95 | 6e-19 | 92.8 |
| LLPS-Anp-0781 | Anas platyrhynchos | 29.44 | 6e-18 | 87.8 |
| LLPS-Mod-1578 | Monodelphis domestica | 29.44 | 6e-19 | 92.4 |
| LLPS-Scm-0179 | Scophthalmus maximus | 29.44 | 5e-17 | 87.0 |
| LLPS-Orn-0182 | Oreochromis niloticus | 29.44 | 5e-18 | 90.1 |
| LLPS-Fia-3043 | Ficedula albicollis | 29.44 | 4e-19 | 93.2 |
| LLPS-Tag-0333 | Taeniopygia guttata | 29.44 | 2e-18 | 91.3 |
| LLPS-Anc-0374 | Anolis carolinensis | 29.44 | 1e-18 | 91.7 |
| LLPS-Orl-1704 | Oryzias latipes | 29.44 | 5e-18 | 90.1 |
| LLPS-Mum-0298 | Mus musculus | 29.44 | 4e-19 | 93.2 |
| LLPS-Scf-2148 | Scleropages formosus | 29.44 | 5e-19 | 93.2 |
| LLPS-Ran-0796 | Rattus norvegicus | 29.44 | 1e-18 | 92.0 |
| LLPS-Meg-0369 | Meleagris gallopavo | 29.21 | 5e-19 | 92.8 |
| LLPS-Pes-0012 | Pelodiscus sinensis | 28.93 | 6e-18 | 89.7 |
| LLPS-Gaa-0776 | Gasterosteus aculeatus | 28.93 | 8e-16 | 83.2 |
| LLPS-Icp-0601 | Ictalurus punctatus | 28.88 | 4e-16 | 84.3 |
| LLPS-Otg-1034 | Otolemur garnettii | 28.86 | 2e-17 | 87.8 |
| LLPS-Miv-1059 | Microbotryum violaceum | 28.54 | 4e-29 | 124 |
| LLPS-Ten-1722 | Tetraodon nigroviridis | 28.43 | 4e-16 | 84.0 |
| LLPS-Cii-1330 | Ciona intestinalis | 28.43 | 8e-16 | 83.2 |
| LLPS-Tar-0381 | Takifugu rubripes | 28.43 | 2e-16 | 85.1 |
| LLPS-Ora-1120 | Ornithorhynchus anatinus | 28.36 | 3e-16 | 84.3 |
| LLPS-Cis-0003 | Ciona savignyi | 28.33 | 1e-09 | 61.6 |
| LLPS-Gas-1227 | Galdieria sulphuraria | 27.98 | 3e-16 | 82.8 |
| LLPS-Xet-3557 | Xenopus tropicalis | 27.81 | 6e-17 | 86.7 |
| LLPS-Asm-0317 | Astyanax mexicanus | 27.81 | 8e-17 | 86.3 |
| LLPS-Aso-0821 | Aspergillus oryzae | 27.71 | 6e-39 | 150 |
| LLPS-Leo-0265 | Lepisosteus oculatus | 26.59 | 2e-19 | 94.0 |
| LLPS-Drm-0629 | Drosophila melanogaster | 26.0 | 4e-14 | 78.2 |
| LLPS-Spr-0786 | Sporisorium reilianum | 24.49 | 3e-17 | 87.8 |