• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Scp-1199
vas2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Valine--tRNA ligase; Valyl-tRNA synthetase; ValRS
Gene Name: vas2, SPBC1709.02c, SPBC1734.18c
Ensembl Gene: SPBC1709.02c
Ensembl Protein: SPBC1709.02c.1
Organism: Schizosaccharomyces pombe
Taxa ID: 284812
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-body, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblSPBC1709.02c.1SPBC1709.02c.1
UniProtO75005, SYV_SCHPO
GeneBankCU329671CAA21312.1
RefSeqNM_001021343.2NP_595435.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MADKGCEAAQ  SKDSSAPGSG  EPRPKTEKEL  ERERQKAAKL  EKYHAKLAAK  KAKEEARKPK  60
61    LDKKAKIASP  VAEYVEKTTP  GEKKVLQDLD  SPALKSYNPK  AVESAWYDWW  VKSGFFEPEF  120
121   GPDGKPKKEG  VFVITSPPPN  VTGALHIGHA  LTIAIQDSLA  RWNRMLGKTV  LFLGGFDHAG  180
181   LSTQSVVEKK  LWYTQKKTRH  DYPRDKFVDI  VWEWKEEYHN  RIKNQMSRLG  GSFDWTREAF  240
241   TMDENLSRAV  VETFVRLHEE  NIIYRANRLV  NWCTALQTTL  SNLEVENVDV  PGRTLLKVPG  300
301   YDEPVEVGVL  TSIAYAVEGS  DERIVIATTR  PETLLGDTAV  AVHPQDPRYK  HLHGKFVKHP  360
361   FCNRSIPIIC  DDIIVDMEFG  TGAVKITPAH  DPNDYEVGKR  HNLEFINIFT  DDGLLNENCG  420
421   EFAGMKRFTA  RVKVVERLKE  LGLFVGTKEN  PMVIPLCGKT  SDIIEPVMKP  QWWVNQKEMA  480
481   AAAAEVVKSG  EIEIAPDMSR  REFIRWMENI  QDWCISRQLW  WGHRIPAYFV  NLADEPSQDR  540
541   SEGRYWVTGR  TLEQAEEKAK  AAFPGKSFTL  EQDEDVLDTW  FSSGLWPFST  LGWPKDTSDY  600
601   ENFYPTTLME  TGWDILFFWI  ARMVMLGLKL  TGKIPFKRVF  CHALVRDAQG  RKMSKSLGNV  660
661   VDPIDVIEGI  SLQALHDKLL  VGNLDSREVE  KAKKGQRLSY  PKGIPQCGTD  ALRFTLCSLT  720
721   TGGRDLNLDI  LRVEGYRKFC  NKLYNATKFA  LGRLGSNFVP  NKTADLTGNE  SLVEKWIFHR  780
781   LNIAAAAMNK  NMEEMNFLQA  TSAVHQFWLY  ELCDVYIENS  KYLLSDGTEV  QQESAKQTLY  840
841   TVLDNALRLM  HPFMPYVTEE  MWQRLPRRPG  DKTQTIVKAA  FPVERVDYSN  EIAAKYYESI  900
901   ITVVHSTRSM  MAENGIKSDA  VVYIHPDEEH  SKLITSESAS  IQSLIKKCKT  LSIVDNTFDS  960
961   DKCVKNEVLE  GSTIFLERNN  980
Nucleotide CDS Sequence (FASTA)
1     ATGGCAGACA  AAGGCTGTGA  AGCTGCTCAG  TCTAAGGATT  CTTCCGCACC  TGGTTCTGGT  60
61    GAGCCTAGGC  CTAAAACCGA  GAAAGAATTA  GAGCGTGAAC  GCCAAAAGGC  GGCTAAGCTT  120
121   GAAAAGTATC  ATGCAAAGCT  GGCGGCCAAG  AAGGCGAAGG  AGGAGGCAAG  AAAGCCTAAA  180
181   CTTGATAAGA  AGGCTAAGAT  TGCTTCACCA  GTTGCCGAGT  ATGTCGAAAA  GACCACTCCT  240
241   GGTGAGAAAA  AAGTCCTTCA  AGACTTGGAC  TCTCCTGCTT  TGAAGTCCTA  TAATCCCAAA  300
301   GCTGTTGAGT  CTGCTTGGTA  TGACTGGTGG  GTCAAGTCTG  GTTTCTTTGA  ACCCGAGTTT  360
361   GGTCCTGATG  GTAAACCTAA  GAAAGAGGGC  GTATTTGTTA  TTACATCTCC  TCCTCCCAAT  420
421   GTCACTGGTG  CTTTGCATAT  TGGCCATGCT  CTTACGATTG  CTATTCAAGA  TTCGTTAGCT  480
481   CGGTGGAACA  GAATGCTTGG  TAAAACAGTT  TTGTTTCTGG  GTGGTTTCGA  TCATGCTGGT  540
541   TTAAGTACCC  AATCTGTTGT  TGAAAAGAAG  CTTTGGTACA  CGCAGAAGAA  GACTCGCCAT  600
601   GATTATCCTC  GTGATAAATT  TGTTGACATT  GTTTGGGAAT  GGAAAGAAGA  ATACCATAAC  660
661   CGTATAAAAA  ACCAAATGTC  TCGACTTGGT  GGTTCTTTTG  ATTGGACTCG  TGAAGCCTTT  720
721   ACTATGGATG  AAAATCTTAG  TCGTGCCGTT  GTTGAAACCT  TTGTTCGTTT  GCATGAGGAA  780
781   AATATTATCT  ACCGTGCTAA  TCGTCTCGTG  AATTGGTGTA  CTGCTTTACA  AACAACTTTA  840
841   TCAAACCTTG  AGGTAGAAAA  CGTTGACGTT  CCTGGCCGTA  CTTTGCTCAA  GGTCCCTGGA  900
901   TATGATGAAC  CCGTCGAAGT  GGGTGTATTG  ACTTCCATCG  CTTATGCCGT  TGAAGGTTCT  960
961   GACGAACGAA  TTGTTATTGC  TACTACACGT  CCAGAAACAC  TTCTCGGAGA  TACTGCTGTT  1020
1021  GCTGTTCATC  CCCAGGATCC  TCGTTATAAG  CACCTACACG  GTAAATTTGT  AAAACATCCC  1080
1081  TTCTGTAACC  GTTCAATTCC  TATCATCTGT  GACGACATAA  TCGTTGATAT  GGAATTTGGT  1140
1141  ACCGGTGCTG  TTAAAATCAC  TCCAGCTCAT  GATCCTAACG  ATTATGAAGT  TGGAAAGCGT  1200
1201  CATAATTTGG  AGTTCATTAA  TATTTTCACT  GACGATGGTC  TTCTCAATGA  AAATTGTGGA  1260
1261  GAATTTGCTG  GCATGAAGCG  TTTTACTGCT  CGTGTTAAGG  TTGTTGAACG  ACTCAAGGAG  1320
1321  CTCGGCTTAT  TTGTTGGTAC  CAAGGAAAAT  CCAATGGTAA  TTCCACTTTG  TGGGAAGACT  1380
1381  TCGGATATTA  TTGAGCCAGT  CATGAAGCCT  CAATGGTGGG  TGAATCAAAA  AGAGATGGCT  1440
1441  GCAGCCGCAG  CTGAAGTTGT  AAAGTCTGGT  GAAATCGAAA  TTGCTCCTGA  TATGTCTCGC  1500
1501  CGAGAATTCA  TTCGCTGGAT  GGAAAATATC  CAAGACTGGT  GCATTTCTCG  TCAATTATGG  1560
1561  TGGGGTCATC  GTATCCCAGC  CTATTTTGTA  AATTTAGCTG  ACGAACCTTC  TCAAGATCGA  1620
1621  AGTGAAGGCC  GTTATTGGGT  TACTGGTCGT  ACTTTGGAAC  AAGCAGAAGA  GAAAGCTAAA  1680
1681  GCTGCTTTTC  CTGGAAAGTC  TTTCACACTA  GAACAGGATG  AAGACGTTCT  TGATACTTGG  1740
1741  TTCTCCTCCG  GATTGTGGCC  TTTTTCTACC  CTTGGCTGGC  CAAAGGATAC  TAGCGATTAT  1800
1801  GAAAATTTCT  ATCCTACTAC  TCTGATGGAA  ACAGGTTGGG  ATATTCTTTT  CTTCTGGATT  1860
1861  GCTCGTATGG  TAATGTTGGG  TCTCAAATTA  ACCGGAAAGA  TTCCCTTTAA  ACGTGTATTT  1920
1921  TGTCATGCAC  TCGTTCGTGA  TGCTCAAGGC  CGCAAAATGT  CTAAATCATT  GGGAAATGTT  1980
1981  GTGGATCCTA  TAGATGTCAT  TGAGGGTATT  TCTCTACAAG  CATTACATGA  TAAGCTTTTG  2040
2041  GTTGGCAATC  TCGACAGCAG  AGAGGTCGAA  AAAGCTAAAA  AGGGTCAACG  GTTGAGCTAT  2100
2101  CCCAAGGGTA  TACCTCAATG  TGGAACTGAC  GCTTTGCGTT  TTACCCTCTG  TTCCTTGACT  2160
2161  ACTGGTGGTC  GTGATCTCAA  CCTTGATATC  CTTCGTGTTG  AAGGATATCG  TAAATTCTGT  2220
2221  AACAAGTTGT  ACAATGCTAC  AAAATTTGCT  TTGGGTCGTC  TAGGTTCTAA  TTTCGTTCCT  2280
2281  AACAAGACTG  CCGATCTTAC  TGGTAATGAA  TCACTTGTAG  AAAAGTGGAT  TTTCCACCGC  2340
2341  TTGAACATCG  CAGCAGCCGC  TATGAACAAA  AACATGGAAG  AAATGAACTT  CCTTCAAGCT  2400
2401  ACTTCAGCTG  TTCACCAATT  TTGGTTGTAT  GAACTTTGTG  ATGTTTACAT  TGAGAACTCA  2460
2461  AAATACCTTC  TAAGTGATGG  TACAGAGGTA  CAACAAGAAT  CTGCTAAGCA  AACCCTCTAT  2520
2521  ACTGTCCTTG  ACAACGCTCT  TCGTTTAATG  CATCCTTTTA  TGCCATACGT  TACTGAAGAG  2580
2581  ATGTGGCAGA  GACTTCCTCG  TCGTCCTGGA  GACAAAACTC  AGACTATCGT  TAAAGCTGCT  2640
2641  TTCCCAGTTG  AAAGGGTAGA  CTATTCTAAC  GAGATAGCTG  CTAAATATTA  CGAGTCTATC  2700
2701  ATTACTGTCG  TTCACTCTAC  TCGTTCAATG  ATGGCTGAAA  ATGGAATCAA  ATCAGATGCT  2760
2761  GTGGTATACA  TTCATCCTGA  TGAAGAACAT  TCCAAACTCA  TTACTTCGGA  ATCTGCCAGT  2820
2821  ATTCAAAGTC  TTATCAAGAA  ATGCAAAACT  TTAAGCATCG  TTGATAATAC  TTTTGATTCG  2880
2881  GACAAATGCG  TTAAAAACGA  GGTTTTAGAA  GGAAGCACTA  TCTTTTTGGA  ACGAAACAAC  2940
2941  TAG  2943

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Scc-0301Schizosaccharomyces cryophilus83.980.01657
LLPS-Scj-0647Schizosaccharomyces japonicus83.280.01567
LLPS-Pes-3142Pelodiscus sinensis64.321e-76 254
LLPS-Sac-1347Saccharomyces cerevisiae63.970.01217
LLPS-Asg-0775Ashbya gossypii63.90.01235
LLPS-Kop-1296Komagataella pastoris63.180.01204
LLPS-Ast-0802Aspergillus terreus61.980.0 899
LLPS-Yal-0110Yarrowia lipolytica61.450.01206
LLPS-Abg-1757Absidia glauca60.50.01155
LLPS-Spr-0510Sporisorium reilianum60.290.01119
LLPS-Gaga-3519Gallus gallus60.298e-46 171
LLPS-Usm-0107Ustilago maydis59.960.01118
LLPS-Myl-0439Myotis lucifugus59.080.0 859
LLPS-Trv-0637Trichoderma virens59.010.01090
LLPS-Aso-0909Aspergillus oryzae58.690.01085
LLPS-Asf-1453Aspergillus flavus58.690.01085
LLPS-Trr-0061Trichoderma reesei58.670.01107
LLPS-Fus-0505Fusarium solani58.110.01094
LLPS-Asc-1199Aspergillus clavatus57.920.01096
LLPS-Fud-1010Fukomys damarensis57.690.0 939
LLPS-Pug-0839Puccinia graminis57.660.01087
LLPS-Mel-0862Melampsora laricipopulina57.550.01060
LLPS-Miv-1277Microbotryum violaceum57.540.01057
LLPS-Blg-0282Blumeria graminis57.460.01083
LLPS-Php-0195Physcomitrella patens57.360.0 960
LLPS-Map-0969Magnaporthe poae57.30.01029
LLPS-Pytr-0764Pyrenophora triticirepentis57.210.01068
LLPS-Pyt-0924Pyrenophora teres56.980.01060
LLPS-Beb-1611Beauveria bassiana56.950.01129
LLPS-Mao-0473Magnaporthe oryzae56.690.01041
LLPS-Asfu-0852Aspergillus fumigatus56.620.01098
LLPS-Lem-0675Leptosphaeria maculans56.610.01073
LLPS-Nef-0609Neosartorya fischeri56.540.01090
LLPS-Zyt-1477Zymoseptoria tritici55.840.01036
LLPS-Osl-1097Ostreococcus lucimarinus55.820.0 960
LLPS-Cogr-1450Colletotrichum graminicola55.820.01029
LLPS-Anc-1402Anolis carolinensis55.820.0 982
LLPS-Cog-1185Colletotrichum gloeosporioides55.820.01031
LLPS-Ora-2962Ornithorhynchus anatinus55.810.0 638
LLPS-Nec-0065Neurospora crassa55.740.01030
LLPS-Coo-0033Colletotrichum orbiculare55.710.01027
LLPS-Ict-3326Ictidomys tridecemlineatus55.690.0 971
LLPS-Asn-0729Aspergillus nidulans55.570.01066
LLPS-Ved-0341Verticillium dahliae55.490.01005
LLPS-Scs-0804Sclerotinia sclerotiorum55.440.0 782
LLPS-Crn-0679Cryptococcus neoformans55.390.01041
LLPS-Caj-2015Callithrix jacchus55.240.0 963
LLPS-Tar-3283Takifugu rubripes55.210.0 846
LLPS-Aon-1976Aotus nancymaae55.190.0 962
LLPS-Caf-0349Canis familiaris55.130.0 964
LLPS-Nol-3187Nomascus leucogenys55.020.0 953
LLPS-Bot-2683Bos taurus55.020.0 976
LLPS-Mam-1128Macaca mulatta54.90.0 957
LLPS-Pap-3385Pan paniscus54.90.0 958
LLPS-Pat-0658Pan troglodytes54.90.0 958
LLPS-Hos-1399Homo sapiens54.90.0 955
LLPS-Man-4505Macaca nemestrina54.90.0 957
LLPS-Rhb-1651Rhinopithecus bieti54.90.0 958
LLPS-Dio-1485Dipodomys ordii54.90.0 967
LLPS-Chs-3382Chlorocebus sabaeus54.90.0 957
LLPS-Maf-4704Macaca fascicularis54.90.0 957
LLPS-Cea-2900Cercocebus atys54.90.0 957
LLPS-Gog-4089Gorilla gorilla54.90.0 957
LLPS-Put-0203Puccinia triticina54.860.01018
LLPS-Loa-0264Loxodonta africana54.840.0 969
LLPS-Eqc-3586Equus caballus54.790.0 968
LLPS-Cas-1198Carlito syrichta54.790.0 959
LLPS-Fec-3092Felis catus54.790.0 964
LLPS-Otg-2352Otolemur garnettii54.790.0 964
LLPS-Orc-3076Oryctolagus cuniculus54.790.0 963
LLPS-Ran-4225Rattus norvegicus54.790.0 963
LLPS-Mup-4009Mustela putorius furo54.730.0 962
LLPS-Sus-2879Sus scrofa54.690.0 966
LLPS-Mum-4225Mus musculus54.680.0 961
LLPS-Aim-2619Ailuropoda melanoleuca54.50.0 963
LLPS-Mea-3110Mesocricetus auratus54.450.0 956
LLPS-Asm-0506Astyanax mexicanus54.360.0 954
LLPS-Cap-4130Cavia porcellus54.240.0 956
LLPS-Gag-1496Gaeumannomyces graminis54.150.01023
LLPS-Mod-0204Monodelphis domestica54.120.0 961
LLPS-Poa-4617Pongo abelii53.890.0 926
LLPS-Phn-0655Phaeosphaeria nodorum53.780.01004
LLPS-Xim-1993Xiphophorus maculatus53.780.0 979
LLPS-Paa-1384Papio anubis53.660.0 919
LLPS-Scf-2794Scleropages formosus53.420.0 956
LLPS-Dos-0480Dothistroma septosporum53.210.01040
LLPS-Orl-3811Oryzias latipes53.020.0 966
LLPS-Chr-0403Chlamydomonas reinhardtii52.820.0 929
LLPS-Dar-0597Danio rerio52.710.0 963
LLPS-Icp-1656Ictalurus punctatus52.640.0 959
LLPS-Pot-0377Populus trichocarpa52.610.0 885
LLPS-Mal-0281Mandrillus leucophaeus52.570.0 906
LLPS-Gaa-2194Gasterosteus aculeatus52.480.0 966
LLPS-Leo-2106Lepisosteus oculatus52.390.01002
LLPS-Mae-2092Manihot esculenta52.290.0 890
LLPS-Ten-1640Tetraodon nigroviridis52.260.0 962
LLPS-Sei-1387Setaria italica52.250.0 886
LLPS-Hea-0079Helianthus annuus52.240.0 879
LLPS-Dac-1706Daucus carota52.160.0 907
LLPS-Sah-0621Sarcophilus harrisii52.060.0 949
LLPS-Orn-1688Oreochromis niloticus52.040.0 970
LLPS-Arl-0637Arabidopsis lyrata52.00.0 885
LLPS-Zem-0647Zea mays51.950.0 899
LLPS-Lep-0193Leersia perrieri51.950.0 886
LLPS-Sob-0655Sorghum bicolor51.890.0 897
LLPS-Scm-2160Scophthalmus maximus51.840.0 963
LLPS-Mua-1654Musa acuminata51.770.0 866
LLPS-Brr-1470Brassica rapa51.760.0 876
LLPS-Art-2219Arabidopsis thaliana51.640.0 881
LLPS-Bro-0870Brassica oleracea51.590.0 875
LLPS-Brn-0274Brassica napus51.590.0 874
LLPS-Pof-2558Poecilia formosa51.460.0 972
LLPS-Glm-2755Glycine max51.450.0 881
LLPS-Vir-0109Vigna radiata51.40.0 889
LLPS-Drm-1687Drosophila melanogaster51.390.0 967
LLPS-Org-0558Oryza glaberrima51.240.0 878
LLPS-Brd-0046Brachypodium distachyon51.060.0 877
LLPS-Sem-2431Selaginella moellendorffii51.050.0 881
LLPS-Cus-1372Cucumis sativus51.030.0 899
LLPS-Ors-0022Oryza sativa51.00.0 879
LLPS-Cym-0430Cyanidioschyzon merolae50.960.0 869
LLPS-Met-0908Medicago truncatula50.930.0 875
LLPS-Sol-0579Solanum lycopersicum50.920.0 902
LLPS-Orbr-1679Oryza brachyantha50.890.0 887
LLPS-Orp-0565Oryza punctata50.880.0 882
LLPS-Tra-0168Triticum aestivum50.710.0 880
LLPS-Cii-0220Ciona intestinalis50.70.0 727
LLPS-Hov-0549Hordeum vulgare50.650.0 878
LLPS-Ori-0840Oryza indica50.530.0 868
LLPS-Tum-0852Tuber melanosporum50.270.0 869
LLPS-Fuo-0753Fusarium oxysporum50.141e-109 353
LLPS-Fuv-0873Fusarium verticillioides50.146e-110 354
LLPS-Amt-1241Amborella trichopoda50.110.0 895
LLPS-Thc-0929Theobroma cacao50.060.0 895
LLPS-Prp-0597Prunus persica50.050.0 890
LLPS-Phv-0438Phaseolus vulgaris49.830.0 882
LLPS-Via-1345Vigna angularis49.830.0 885
LLPS-Gas-0510Galdieria sulphuraria49.720.0 879
LLPS-Tru-0184Triticum urartu49.70.0 842
LLPS-Xet-2034Xenopus tropicalis49.670.0 879
LLPS-Orni-1151Oryza nivara49.350.0 843
LLPS-Coc-0751Corchorus capsularis49.220.0 862
LLPS-Gor-0779Gossypium raimondii48.90.0 878
LLPS-Lac-0394Latimeria chalumnae48.770.0 868
LLPS-Meg-2450Meleagris gallopavo48.753e-104 338
LLPS-Chc-0270Chondrus crispus48.740.0 846
LLPS-Urm-3706Ursus maritimus48.370.0 809
LLPS-Orm-0427Oryza meridionalis48.350.0 809
LLPS-Cae-0164Caenorhabditis elegans48.10.0 880
LLPS-Orgl-2388Oryza glumaepatula47.860.0 865
LLPS-Ova-4450Ovis aries47.680.0 780
LLPS-Orr-1630Oryza rufipogon47.190.0 860
LLPS-Nia-1995Nicotiana attenuata46.430.0 660
LLPS-Orb-1063Oryza barthii45.720.0 809
LLPS-Viv-2082Vitis vinifera38.790.0 591
LLPS-Cis-1141Ciona savignyi36.640.0 578
LLPS-Fia-0325Ficedula albicollis24.039e-35 148
LLPS-Tag-2240Taeniopygia guttata23.971e-35 151
LLPS-Anp-0049Anas platyrhynchos23.946e-37 155
LLPS-Asni-0661Aspergillus niger22.881e-37 157
LLPS-Sot-1524Solanum tuberosum22.251e-41 170