• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Scp-1198
uap2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Splicing factor U2AF-associated protein 2; Cold sensitive U2 snRNA suppressor 2 homolog
Gene Name: uap2, SPBC1289.02c
Ensembl Gene: SPBC1289.02c
Ensembl Protein: SPBC1289.02c.1
Organism: Schizosaccharomyces pombe
Taxa ID: 284812
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, NucleolusPredicted from orthologs(View)

▼ FUNCTION

Has a role in pre-mRNA splicing.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSSQPFWDER  IHRWRCLGSE  GNELIYIDEE  QTWKDYDPNS  LKMNKAGSTG  AEVSDVTAEA  60
61    TEGKESSNGE  DRHTKRLYES  TSAEGYPSGS  RNKKSKSENS  EASPAPVINK  AVYIQGLPLD  120
121   VTVDEIEEVF  KKCGVIAKNI  DNGTPRIKIY  RTEDGTPKGD  ALIVFFRSES  VELAEQLFDD  180
181   TEFRYGSGQK  MRVQKANIDY  KKEKTVNKDV  GGALKKKALR  LRQQQMQQIS  SWDDVDEEVD  240
241   DKRKKRFNKI  VVLKHIFTLE  ELDKTPELLI  DLKDDITEEA  EKCGRVTNVV  LYDKEPDGVV  300
301   TVRFSNNEEA  EACVRLMQGR  YFDGRVVEAS  IYDGKVRFQK  SGKHTLDDEE  DEEKRLEKFA  360
361   DWLENSN  367
Nucleotide CDS Sequence (FASTA)
1     ATGTCCAGCC  AGCCTTTTTG  GGATGAAAGA  ATACATCGTT  GGAGATGTTT  AGGATCAGAA  60
61    GGAAACGAAT  TAATATATAT  TGATGAAGAA  CAAACTTGGA  AAGATTATGA  TCCTAATAGC  120
121   TTAAAAATGA  ATAAGGCCGG  CTCAACTGGT  GCAGAAGTCA  GTGATGTTAC  GGCGGAGGCT  180
181   ACCGAAGGAA  AGGAATCTAG  CAACGGCGAA  GACCGCCATA  CCAAACGATT  GTACGAATCG  240
241   ACATCGGCTG  AAGGGTATCC  TTCAGGTTCT  CGAAATAAAA  AGTCAAAGTC  CGAAAATTCA  300
301   GAAGCCTCGC  CCGCCCCAGT  AATAAACAAA  GCGGTTTACA  TTCAAGGACT  ACCACTGGAT  360
361   GTCACGGTTG  ACGAAATTGA  AGAAGTATTC  AAGAAATGCG  GTGTTATTGC  TAAGAATATT  420
421   GACAATGGTA  CGCCGAGAAT  CAAAATCTAC  CGGACAGAGG  ATGGAACTCC  TAAAGGTGAT  480
481   GCTTTAATTG  TATTTTTCCG  CAGCGAAAGT  GTTGAGCTTG  CAGAGCAATT  ATTTGATGAC  540
541   ACTGAATTTC  GTTATGGATC  TGGGCAAAAG  ATGCGTGTCC  AGAAAGCTAA  TATTGATTAC  600
601   AAAAAGGAGA  AAACGGTGAA  CAAAGACGTA  GGTGGTGCCT  TAAAAAAAAA  GGCACTTCGT  660
661   CTCCGACAAC  AACAAATGCA  GCAAATTTCA  TCCTGGGATG  ATGTTGACGA  AGAGGTTGAT  720
721   GATAAAAGAA  AAAAACGATT  TAATAAAATA  GTAGTTTTAA  AGCATATTTT  TACGCTGGAA  780
781   GAACTCGATA  AAACACCTGA  ACTTTTAATT  GACTTAAAAG  ACGATATCAC  TGAGGAAGCT  840
841   GAGAAATGTG  GACGAGTTAC  TAATGTGGTT  TTGTACGACA  AGGAGCCTGA  TGGAGTAGTA  900
901   ACTGTACGGT  TTTCAAACAA  TGAAGAAGCT  GAAGCTTGCG  TAAGGTTAAT  GCAAGGCCGA  960
961   TATTTTGATG  GCCGGGTAGT  GGAAGCTTCA  ATTTACGATG  GAAAGGTTCG  GTTCCAGAAA  1020
1021  AGTGGAAAGC  ATACATTAGA  TGATGAAGAG  GACGAGGAAA  AACGTTTGGA  AAAATTCGCA  1080
1081  GATTGGTTAG  AAAATTCTAA  CTGA  1104

▼ KEYWORD

ID
Family
Complete proteome
mRNA processing
mRNA splicing
Reference proteome
Repeat
RNA-binding

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
U2 snRNP
Cellular Component
U2-type spliceosomal complex
Molecular Function
RNA binding
Biological Process
MRNA cis splicing, via spliceosome

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Scc-0563Schizosaccharomyces cryophilus60.761e-140 412
LLPS-Mao-1362Magnaporthe oryzae55.561e-25 110
LLPS-Gag-0879Gaeumannomyces graminis55.325e-28 117
LLPS-Scj-0482Schizosaccharomyces japonicus52.058e-116 348
LLPS-Blg-0176Blumeria graminis48.159e-66 219
LLPS-Asni-0562Aspergillus niger47.083e-72 237
LLPS-Cog-0138Colletotrichum gloeosporioides46.95e-67 223
LLPS-Ast-0972Aspergillus terreus46.529e-72 235
LLPS-Asfu-0245Aspergillus fumigatus46.352e-72 237
LLPS-Cogr-0437Colletotrichum graminicola46.045e-67 224
LLPS-Asc-1001Aspergillus clavatus45.992e-70 232
LLPS-Asn-0645Aspergillus nidulans45.995e-71 234
LLPS-Coo-0526Colletotrichum orbiculare45.951e-64 217
LLPS-Beb-0295Beauveria bassiana45.957e-59 201
LLPS-Asf-0356Aspergillus flavus45.822e-70 232
LLPS-Nef-0432Neosartorya fischeri45.621e-71 235
LLPS-Fus-1456Fusarium solani45.494e-60 204
LLPS-Coc-0027Corchorus capsularis45.196e-1988.2
LLPS-Trv-0499Trichoderma virens44.716e-56 193
LLPS-Tum-0395Tuber melanosporum44.692e-74 243
LLPS-Abg-1271Absidia glauca44.42e-65 218
LLPS-Put-1142Puccinia triticina43.052e-1888.6
LLPS-Trr-0355Trichoderma reesei42.972e-56 194
LLPS-Aso-0225Aspergillus oryzae42.765e-65 219
LLPS-Map-0066Magnaporthe poae42.54e-60 204
LLPS-Mel-1339Melampsora laricipopulina42.423e-48 173
LLPS-Lem-0210Leptosphaeria maculans42.218e-48 170
LLPS-Nec-0360Neurospora crassa42.123e-61 209
LLPS-Kop-0697Komagataella pastoris40.771e-45 165
LLPS-Crn-0138Cryptococcus neoformans40.582e-49 177
LLPS-Pyt-0961Pyrenophora teres40.417e-44 159
LLPS-Pytr-1355Pyrenophora triticirepentis40.08e-43 157
LLPS-Osl-0958Ostreococcus lucimarinus39.929e-44 160
LLPS-Anc-2346Anolis carolinensis39.532e-1066.2
LLPS-Otg-0756Otolemur garnettii39.473e-0859.3
LLPS-Leo-0508Lepisosteus oculatus39.331e-0860.8
LLPS-Chr-0079Chlamydomonas reinhardtii39.083e-40 154
LLPS-Ved-1464Verticillium dahliae38.36e-47 171
LLPS-Mua-1310Musa acuminata38.266e-35 138
LLPS-Scf-1222Scleropages formosus38.28e-0961.6
LLPS-Tag-1643Taeniopygia guttata38.169e-0960.8
LLPS-Gaga-2774Gallus gallus38.168e-0960.8
LLPS-Anp-2499Anas platyrhynchos38.161e-0860.8
LLPS-Meg-2407Meleagris gallopavo38.161e-0860.8
LLPS-Fia-3041Ficedula albicollis38.169e-0960.8
LLPS-Mod-2572Monodelphis domestica38.12e-1169.7
LLPS-Zem-0482Zea mays37.931e-37 146
LLPS-Sob-1373Sorghum bicolor37.791e-37 146
LLPS-Bot-0450Bos taurus37.667e-0858.5
LLPS-Tut-0706Tursiops truncatus37.664e-0858.9
LLPS-Aim-1767Ailuropoda melanoleuca37.667e-0858.2
LLPS-Mup-3934Mustela putorius furo37.664e-0858.9
LLPS-Myl-1654Myotis lucifugus37.665e-0858.9
LLPS-Ova-2813Ovis aries37.665e-0858.5
LLPS-Paa-2805Papio anubis37.666e-0858.5
LLPS-Mal-0327Mandrillus leucophaeus37.665e-0858.5
LLPS-Ran-2071Rattus norvegicus37.664e-0858.9
LLPS-Sus-2766Sus scrofa37.665e-0858.5
LLPS-Aon-1789Aotus nancymaae37.665e-0858.5
LLPS-Cea-2587Cercocebus atys37.665e-0858.5
LLPS-Chs-3443Chlorocebus sabaeus37.665e-0858.5
LLPS-Maf-2006Macaca fascicularis37.665e-0858.5
LLPS-Mum-1823Mus musculus37.665e-0858.9
LLPS-Caj-3049Callithrix jacchus37.665e-0858.9
LLPS-Fud-1253Fukomys damarensis37.665e-0858.9
LLPS-Gog-0124Gorilla gorilla37.664e-0858.9
LLPS-Mam-2037Macaca mulatta37.665e-0858.5
LLPS-Eqc-4087Equus caballus37.665e-0858.5
LLPS-Poa-3261Pongo abelii37.664e-0858.9
LLPS-Caf-3069Canis familiaris37.666e-0858.5
LLPS-Nol-0708Nomascus leucogenys37.664e-0858.9
LLPS-Ict-4241Ictidomys tridecemlineatus37.666e-0858.5
LLPS-Cas-1531Carlito syrichta37.665e-0858.9
LLPS-Loa-2730Loxodonta africana37.664e-0858.9
LLPS-Man-2244Macaca nemestrina37.665e-0858.5
LLPS-Hos-1528Homo sapiens37.665e-0858.5
LLPS-Pat-4699Pan troglodytes37.664e-0858.9
LLPS-Urm-1602Ursus maritimus37.665e-0858.5
LLPS-Rhb-2748Rhinopithecus bieti37.665e-0858.9
LLPS-Orc-1669Oryctolagus cuniculus37.665e-0858.5
LLPS-Yal-1360Yarrowia lipolytica37.453e-36 140
LLPS-Hea-0597Helianthus annuus37.392e-33 134
LLPS-Cii-1348Ciona intestinalis37.231e-41 157
LLPS-Amt-1962Amborella trichopoda37.212e-35 140
LLPS-Usm-0430Ustilago maydis37.098e-40 152
LLPS-Vir-0473Vigna radiata37.072e-37 146
LLPS-Glm-2333Glycine max37.072e-37 145
LLPS-Thc-1265Theobroma cacao37.071e-35 140
LLPS-Fuv-0053Fusarium verticillioides37.057e-60 204
LLPS-Spr-1389Sporisorium reilianum37.058e-47 171
LLPS-Phn-0532Phaeosphaeria nodorum37.044e-39 147
LLPS-Sei-1533Setaria italica37.022e-36 142
LLPS-Sah-2286Sarcophilus harrisii36.943e-1272.0
LLPS-Miv-1167Microbotryum violaceum36.939e-48 174
LLPS-Zyt-1533Zymoseptoria tritici36.923e-33 131
LLPS-Dos-0309Dothistroma septosporum36.843e-40 152
LLPS-Via-0173Vigna angularis36.684e-38 148
LLPS-Sol-1642Solanum lycopersicum36.686e-28 118
LLPS-Prp-1836Prunus persica36.682e-29 122
LLPS-Phv-1267Phaseolus vulgaris36.683e-37 145
LLPS-Orbr-1470Oryza brachyantha36.46e-35 138
LLPS-Cap-4317Cavia porcellus36.366e-0858.5
LLPS-Nia-1307Nicotiana attenuata36.291e-34 137
LLPS-Viv-0597Vitis vinifera36.263e-28 117
LLPS-Fuo-0404Fusarium oxysporum36.215e-60 204
LLPS-Mea-1617Mesocricetus auratus36.198e-1167.4
LLPS-Met-2481Medicago truncatula36.054e-35 139
LLPS-Sem-1352Selaginella moellendorffii36.059e-39 149
LLPS-Pot-1947Populus trichocarpa36.053e-36 142
LLPS-Orp-0977Oryza punctata36.024e-34 136
LLPS-Dar-3250Danio rerio35.931e-34 137
LLPS-Dac-2016Daucus carota35.669e-36 140
LLPS-Php-0563Physcomitrella patens35.662e-32 130
LLPS-Lep-0463Leersia perrieri35.632e-34 137
LLPS-Orm-0390Oryza meridionalis35.633e-34 137
LLPS-Gor-2502Gossypium raimondii35.522e-34 137
LLPS-Dio-1039Dipodomys ordii35.143e-1167.8
LLPS-Ora-2576Ornithorhynchus anatinus35.146e-1168.2
LLPS-Fec-1353Felis catus35.143e-1168.9
LLPS-Pap-2087Pan paniscus35.145e-1168.6
LLPS-Hov-0877Hordeum vulgare35.118e-32 130
LLPS-Cus-1534Cucumis sativus34.885e-34 135
LLPS-Art-0955Arabidopsis thaliana34.883e-32 130
LLPS-Mae-0158Manihot esculenta34.888e-32 129
LLPS-Icp-1615Ictalurus punctatus34.632e-33 134
LLPS-Pes-2226Pelodiscus sinensis34.557e-0961.6
LLPS-Tra-0924Triticum aestivum34.482e-31 127
LLPS-Lac-1061Latimeria chalumnae34.235e-1065.1
LLPS-Cis-0317Ciona savignyi34.25e-40 152
LLPS-Arl-0102Arabidopsis lyrata34.113e-31 127
LLPS-Brn-0707Brassica napus34.112e-31 127
LLPS-Brr-0321Brassica rapa34.111e-31 129
LLPS-Drm-0376Drosophila melanogaster33.779e-36 141
LLPS-Orl-3437Oryzias latipes33.771e-29 122
LLPS-Pof-0957Poecilia formosa33.775e-34 135
LLPS-Orgl-0431Oryza glumaepatula33.753e-34 136
LLPS-Ori-1574Oryza indica33.752e-34 136
LLPS-Orb-0294Oryza barthii33.755e-34 135
LLPS-Orni-1311Oryza nivara33.752e-34 136
LLPS-Orr-0450Oryza rufipogon33.752e-34 137
LLPS-Org-1054Oryza glaberrima33.755e-34 135
LLPS-Ors-0986Oryza sativa33.752e-34 136
LLPS-Brd-1092Brachypodium distachyon33.736e-30 124
LLPS-Chc-0286Chondrus crispus33.337e-34 134
LLPS-Cae-1046Caenorhabditis elegans33.337e-35 137
LLPS-Bro-1150Brassica oleracea33.331e-31 129
LLPS-Tru-1275Triticum urartu33.063e-25 110
LLPS-Tar-3390Takifugu rubripes32.93e-32 130
LLPS-Orn-1976Oreochromis niloticus32.94e-32 130
LLPS-Asm-1867Astyanax mexicanus32.761e-34 137
LLPS-Gas-0762Galdieria sulphuraria32.558e-39 148
LLPS-Ten-0179Tetraodon nigroviridis32.471e-30 125
LLPS-Scm-0072Scophthalmus maximus32.474e-31 127
LLPS-Xet-1720Xenopus tropicalis32.334e-33 133
LLPS-Gaa-0721Gasterosteus aculeatus31.85e-33 132
LLPS-Xim-0498Xiphophorus maculatus31.382e-32 130
LLPS-Sac-1246Saccharomyces cerevisiae29.612e-1785.1