DrLLPS - Data resource of LLPS

LLPS-Scp-0349
lsm7

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	U6 snRNA-associated Sm-like protein LSm7
Gene Name:	lsm7, SPCC285.12
Ensembl Gene:	SPCC285.12
Ensembl Protein:	SPCC285.12.1
Organism:	Schizosaccharomyces pombe
Taxa ID:	284812
LLPS Type:	Client

PDB: 3SWN (C, A, B) More

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
P-body, Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Saccharomyces cerevisiae	LLPS-Sac-0625	P53905	Client	P-body, Stress granule	46.94	6e-24	94.4

▼ FUNCTION

Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. Probable component of the spliceosome.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	SPCC285.12.1	SPCC285.12.1
UniProt		O74499, LSM7_SCHPO
GeneBank	CU329672	CAA20851.1
RefSeq	NM_001023331.2	NP_588340.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MSSLQKRPGP GNSSQPTERP RKESILDLSR YQDQRIQATF TGGRQITGIL KGFDQLMNLV 60 61 LDDVEEQLRN PEDGKLTGAI RKLGLVVVRG TTLVLIAPMD GSEEIPNPFV QAE 113
Nucleotide CDS Sequence (FASTA)
1 ATGTCCAGTC TTCAAAAACG CCCTGGCCCA GGTAACTCTA GTCAACCGAC TGAAAGACCA 60 61 AGAAAAGAAT CTATCCTTGA TCTTTCTAGA TATCAAGATC AACGAATTCA AGCCACGTTT 120 121 ACGGGGGGCC GACAAATTAC CGGTATTCTA AAAGGATTCG ATCAGTTGAT GAACCTTGTA 180 181 CTTGACGATG TAGAGGAACA GCTTCGCAAT CCTGAGGATG GTAAACTTAC TGGAGCTATT 240 241 AGAAAGTTAG GTCTTGTAGT CGTTCGTGGA ACAACTTTAG TTTTGATTGC TCCCATGGAT 300 301 GGTTCTGAGG AGATACCGAA TCCATTCGTC CAAGCTGAAT AA 342

▼ KEYWORD

ID	Family
KW-0002	3D-structure
KW-0181	Complete proteome
KW-0963	Cytoplasm
KW-0507	mRNA processing
KW-0508	mRNA splicing
KW-0539	Nucleus
KW-1185	Reference proteome
KW-0687	Ribonucleoprotein
KW-0694	RNA-binding
KW-0698	rRNA processing
KW-0747	Spliceosome
KW-0819	tRNA processing

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0071013	Cellular Component	Catalytic step 2 spliceosome
GO:0005829	Cellular Component	Cytosol
GO:1990726	Cellular Component	Lsm1-7-Pat1 complex
GO:0120115	Cellular Component	Lsm2-8 complex
GO:0005634	Cellular Component	Nucleus
GO:0005681	Cellular Component	Spliceosomal complex
GO:0005689	Cellular Component	U12-type spliceosomal complex
GO:0071004	Cellular Component	U2-type prespliceosome
GO:0046540	Cellular Component	U4/U6 x U5 tri-snRNP complex
GO:0005688	Cellular Component	U6 snRNP
GO:0008266	Molecular Function	Poly(U) RNA binding
GO:0030490	Biological Process	Maturation of SSU-rRNA
GO:0045292	Biological Process	MRNA cis splicing, via spliceosome
GO:0000956	Biological Process	Nuclear-transcribed mRNA catabolic process
GO:1905323	Biological Process	Telomerase holoenzyme complex assembly
GO:0008033	Biological Process	TRNA processing

▼ KEGG

spo:SPCC285.12

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Scc-0795	Schizosaccharomyces cryophilus	84.96	5e-55	174
LLPS-Scj-0770	Schizosaccharomyces japonicus	84.68	1e-50	162
LLPS-Blg-0547	Blumeria graminis	65.69	3e-29	108
LLPS-Ora-2129	Ornithorhynchus anatinus	64.62	3e-10	58.2
LLPS-Eqc-1486	Equus caballus	62.92	9e-20	84.3
LLPS-Poa-4282	Pongo abelii	62.86	3e-11	60.8
LLPS-Fuv-0841	Fusarium verticillioides	62.63	3e-25	98.2
LLPS-Fuo-1367	Fusarium oxysporum	62.63	4e-25	97.8
LLPS-Nec-0548	Neurospora crassa	62.5	5e-25	97.8
LLPS-Loa-0154	Loxodonta africana	62.5	3e-12	63.9
LLPS-Fus-0326	Fusarium solani	62.5	3e-24	95.9
LLPS-Beb-1215	Beauveria bassiana	62.37	2e-22	91.3
LLPS-Ran-0331	Rattus norvegicus	62.11	3e-23	92.0
LLPS-Mum-4473	Mus musculus	62.11	2e-23	92.4
LLPS-Fud-1258	Fukomys damarensis	61.96	4e-22	89.0
LLPS-Scf-0062	Scleropages formosus	61.76	5e-11	60.5
LLPS-Pytr-1338	Pyrenophora triticirepentis	61.62	9e-26	99.4
LLPS-Zyt-0304	Zymoseptoria tritici	61.54	3e-15	70.9
LLPS-Asfu-1135	Aspergillus fumigatus	61.54	8e-19	81.3
LLPS-Ved-0578	Verticillium dahliae	61.46	1e-23	94.0
LLPS-Otg-0483	Otolemur garnettii	61.22	1e-23	92.8
LLPS-Dio-2341	Dipodomys ordii	61.05	4e-23	91.7
LLPS-Bot-0597	Bos taurus	61.05	5e-23	91.7
LLPS-Paa-1662	Papio anubis	61.05	5e-23	91.7
LLPS-Mal-0564	Mandrillus leucophaeus	61.05	5e-23	91.7
LLPS-Cea-3302	Cercocebus atys	61.05	5e-23	91.7
LLPS-Aon-2929	Aotus nancymaae	61.05	5e-23	91.7
LLPS-Sus-0882	Sus scrofa	61.05	6e-23	91.3
LLPS-Maf-1278	Macaca fascicularis	61.05	5e-23	91.7
LLPS-Chs-2299	Chlorocebus sabaeus	61.05	5e-23	91.7
LLPS-Gog-1965	Gorilla gorilla	61.05	5e-23	91.7
LLPS-Mam-4295	Macaca mulatta	61.05	5e-23	91.7
LLPS-Cap-0433	Cavia porcellus	61.05	5e-23	91.7
LLPS-Nol-2447	Nomascus leucogenys	61.05	5e-23	91.7
LLPS-Xet-2616	Xenopus tropicalis	61.05	6e-23	91.3
LLPS-Man-0995	Macaca nemestrina	61.05	5e-23	91.7
LLPS-Pap-1559	Pan paniscus	61.05	5e-23	91.7
LLPS-Pat-1117	Pan troglodytes	61.05	5e-23	91.7
LLPS-Hos-0813	Homo sapiens	61.05	5e-23	91.7
LLPS-Mod-0844	Monodelphis domestica	61.05	7e-23	91.3
LLPS-Fec-2030	Felis catus	61.05	4e-23	92.0
LLPS-Rhb-2571	Rhinopithecus bieti	61.05	5e-23	91.7
LLPS-Usm-1334	Ustilago maydis	60.78	9e-29	107
LLPS-Meg-2485	Meleagris gallopavo	60.67	6e-20	84.0
LLPS-Map-0659	Magnaporthe poae	60.64	2e-22	91.3
LLPS-Cogr-0136	Colletotrichum graminicola	60.64	4e-23	92.8
LLPS-Pyt-0606	Pyrenophora teres	60.61	2e-25	98.2
LLPS-Dos-0534	Dothistroma septosporum	60.44	1e-21	89.0
LLPS-Lac-1577	Latimeria chalumnae	60.44	3e-20	84.3
LLPS-Gag-0640	Gaeumannomyces graminis	60.42	2e-23	93.6
LLPS-Asc-1297	Aspergillus clavatus	60.42	1e-26	101
LLPS-Asni-1413	Aspergillus niger	60.42	1e-24	96.7
LLPS-Asn-1535	Aspergillus nidulans	60.42	1e-26	102
LLPS-Nef-0490	Neosartorya fischeri	60.42	2e-26	101
LLPS-Myl-0380	Myotis lucifugus	60.2	3e-23	92.0
LLPS-Mea-0289	Mesocricetus auratus	60.0	2e-23	92.8
LLPS-Cii-2108	Ciona intestinalis	60.0	2e-23	92.4
LLPS-Icp-1178	Ictalurus punctatus	60.0	2e-22	90.1
LLPS-Spr-0579	Sporisorium reilianum	59.8	1e-27	104
LLPS-Lem-0583	Leptosphaeria maculans	59.79	8e-24	96.3
LLPS-Ast-0640	Aspergillus terreus	59.38	2e-25	98.6
LLPS-Cog-0583	Colletotrichum gloeosporioides	59.38	2e-20	85.5
LLPS-Trr-0773	Trichoderma reesei	59.22	1e-23	92.8
LLPS-Ova-4233	Ovis aries	59.0	3e-23	92.0
LLPS-Aim-1516	Ailuropoda melanoleuca	59.0	2e-23	92.4
LLPS-Caf-1774	Canis familiaris	59.0	2e-23	92.4
LLPS-Tar-1343	Takifugu rubripes	58.95	2e-22	90.1
LLPS-Asm-1051	Astyanax mexicanus	58.95	7e-22	88.6
LLPS-Ten-2492	Tetraodon nigroviridis	58.95	2e-22	90.1
LLPS-Tum-0042	Tuber melanosporum	58.82	9e-23	91.7
LLPS-Trv-1196	Trichoderma virens	58.82	1e-22	91.7
LLPS-Ict-0027	Ictidomys tridecemlineatus	58.82	1e-23	93.2
LLPS-Tag-2665	Taeniopygia guttata	58.76	1e-22	90.5
LLPS-Anp-0138	Anas platyrhynchos	58.76	1e-22	90.5
LLPS-Fia-1679	Ficedula albicollis	58.76	1e-22	90.5
LLPS-Mao-0968	Magnaporthe oryzae	58.51	1e-21	89.0
LLPS-Coo-1058	Colletotrichum orbiculare	58.42	5e-24	95.5
LLPS-Asf-0328	Aspergillus flavus	58.33	2e-28	106
LLPS-Pof-0502	Poecilia formosa	58.16	2e-22	90.5
LLPS-Mel-1286	Melampsora laricipopulina	58.06	3e-22	89.7
LLPS-Gaa-1343	Gasterosteus aculeatus	58.0	3e-22	89.7
LLPS-Orl-3430	Oryzias latipes	58.0	2e-22	90.5
LLPS-Leo-2236	Lepisosteus oculatus	58.0	1e-22	90.5
LLPS-Urm-3326	Ursus maritimus	57.55	3e-20	85.1
LLPS-Crn-0820	Cryptococcus neoformans	57.45	4e-19	81.3
LLPS-Php-0177	Physcomitrella patens	57.45	6e-24	95.5
LLPS-Xim-0645	Xiphophorus maculatus	57.0	1e-22	90.5
LLPS-Gas-0396	Galdieria sulphuraria	56.82	9e-18	78.2
LLPS-Dar-1786	Danio rerio	56.7	5e-22	89.0
LLPS-Arl-0841	Arabidopsis lyrata	56.38	3e-23	92.0
LLPS-Pug-0615	Puccinia graminis	56.25	2e-24	95.5
LLPS-Scm-2476	Scophthalmus maximus	55.88	4e-22	89.4
LLPS-Amt-0515	Amborella trichopoda	55.79	5e-22	90.1
LLPS-Sot-0675	Solanum tuberosum	55.43	1e-21	87.8
LLPS-Via-0041	Vigna angularis	55.43	3e-22	89.4
LLPS-Cus-1522	Cucumis sativus	55.43	4e-22	89.0
LLPS-Met-0275	Medicago truncatula	55.43	6e-22	88.6
LLPS-Sol-2344	Solanum lycopersicum	55.43	1e-21	87.8
LLPS-Glm-0815	Glycine max	55.43	7e-22	88.6
LLPS-Thc-0667	Theobroma cacao	55.43	2e-22	89.7
LLPS-Mua-1795	Musa acuminata	55.43	2e-22	90.1
LLPS-Dac-1838	Daucus carota	55.43	9e-22	88.2
LLPS-Pot-0518	Populus trichocarpa	55.43	9e-22	88.2
LLPS-Viv-1670	Vitis vinifera	55.43	2e-22	90.5
LLPS-Mae-2649	Manihot esculenta	55.43	2e-22	90.1
LLPS-Phv-1783	Phaseolus vulgaris	55.43	3e-22	89.4
LLPS-Bro-1247	Brassica oleracea	55.32	3e-22	89.4
LLPS-Art-2767	Arabidopsis thaliana	55.32	2e-22	90.1
LLPS-Sem-0205	Selaginella moellendorffii	54.95	9e-20	83.2
LLPS-Drm-1961	Drosophila melanogaster	54.9	2e-19	82.0
LLPS-Orgl-1514	Oryza glumaepatula	54.44	4e-20	84.0
LLPS-Orb-0505	Oryza barthii	54.44	4e-20	84.0
LLPS-Ori-0943	Oryza indica	54.44	4e-20	84.0
LLPS-Orni-1498	Oryza nivara	54.44	4e-20	84.0
LLPS-Orr-1103	Oryza rufipogon	54.44	4e-20	84.0
LLPS-Orm-0888	Oryza meridionalis	54.44	4e-20	84.0
LLPS-Orp-1655	Oryza punctata	54.44	4e-20	84.0
LLPS-Ors-0287	Oryza sativa	54.44	6e-20	83.6
LLPS-Orbr-0599	Oryza brachyantha	54.44	4e-20	84.0
LLPS-Hea-0035	Helianthus annuus	54.35	2e-21	87.0
LLPS-Prp-1118	Prunus persica	54.35	9e-21	85.5
LLPS-Gor-1126	Gossypium raimondii	54.35	3e-21	86.7
LLPS-Brr-0965	Brassica rapa	54.26	3e-20	87.0
LLPS-Sei-0704	Setaria italica	53.85	4e-20	84.0
LLPS-Sob-0828	Sorghum bicolor	53.85	4e-20	84.0
LLPS-Orn-1503	Oreochromis niloticus	53.33	2e-21	87.4
LLPS-Tra-2215	Triticum aestivum	53.19	2e-19	82.0
LLPS-Brd-2310	Brachypodium distachyon	52.13	8e-20	83.2
LLPS-Miv-1276	Microbotryum violaceum	52.13	8e-25	96.7
LLPS-Chr-1326	Chlamydomonas reinhardtii	51.61	2e-18	79.7
LLPS-Tru-1427	Triticum urartu	51.55	2e-18	81.6
LLPS-Abg-1600	Absidia glauca	51.06	9e-21	86.7
LLPS-Vir-0226	Vigna radiata	50.5	2e-19	82.4
LLPS-Chc-0320	Chondrus crispus	50.0	1e-19	85.5
LLPS-Asg-1206	Ashbya gossypii	50.0	6e-17	75.9
LLPS-Cae-1483	Caenorhabditis elegans	48.94	6e-20	83.6
LLPS-Osl-0316	Ostreococcus lucimarinus	48.91	6e-19	80.9
LLPS-Sac-0625	Saccharomyces cerevisiae	46.58	9e-17	75.5
LLPS-Kop-1028	Komagataella pastoris	46.39	1e-16	76.3
LLPS-Phn-0824	Phaeosphaeria nodorum	46.15	2e-18	81.3
LLPS-Yal-1336	Yarrowia lipolytica	45.92	1e-13	67.8
LLPS-Mup-1179	Mustela putorius furo	42.5	3e-06	45.8
LLPS-Ere-0219	Erinaceus europaeus	42.5	3e-06	46.2
LLPS-Caj-1413	Callithrix jacchus	42.5	3e-06	46.2
LLPS-Cas-0699	Carlito syrichta	42.5	3e-06	46.2
LLPS-Orc-0726	Oryctolagus cuniculus	42.5	3e-06	45.8
LLPS-Put-0596	Puccinia triticina	41.46	2e-06	46.2

LLPS-Scp-0349lsm7

Protein Sequence

Nucleotide Sequence

LLPS-Scp-0349
lsm7