LLPS-Scp-0194
nsp1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Nucleoporin nsp1; Nuclear pore protein nsp1; Nucleoskeletal-like protein |
| Gene Name: | nsp1, SPAC26A3.15c |
| Ensembl Gene: | SPAC26A3.15c |
| Ensembl Protein: | SPAC26A3.15c.1 |
| Organism: | Schizosaccharomyces pombe |
| Taxa ID: | 284812 |
| LLPS Type: | Scaffold |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Droplet, Nuclear pore complex, Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. Appears to have a role in the formation of the septum. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | SPAC26A3.15c.1 | SPAC26A3.15c.1 |
| UniProt | Q10168, NSP1_SCHPO | |
| GeneBank | CU329670 | CAA93238.1 |
| RefSeq | NM_001019582.2 | NP_594158.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSFNPGNNQN SGFSFGKPAQ PNSAAQGAAT PAATGLFGNT NNNTSSTAPS GGLFGSNNAS 60 61 NTSAPSTFSF GKAATTGNST NASTSSPFSF GSTNTNNTAG AKPLFGGLGS TGSANSTGDK 120 121 SKNTASSATG AATTNPSGST FNFGSSNNSF NFGKPASTTN TTTPAAASTG SLFGKPAATG 180 181 TTSNAPPASS TSTTPATGSG GFSFGKPASL GSTNNASTST TANSGFSFGK PATTSAPGSN 240 241 TTVTPSSSIT GTNDSKPAAS NTGSAPTTGF SFGKPAGQAA STATDKGTTT TSSAGTGFSF 300 301 GKPATTEDTN KPTAPNSAFT KPATSTGDNK PTFSFGNTSK PTENTSTTAT SAPPLSNNTK 360 361 PAEGANQTSS GFSFGKPATD TTTSTSKTGP LFGNKPADPS AKPGATASTT PSEPPPSSIK 420 421 HKTLQEILNK WSTDLTTQTE VFNKLCDQVS DWDRTLVDNG ALISKLYTET VEAEQMSNRI 480 481 DDGLEYVSSS QQELFKLLDS YETQLETFDG RATSALNVER ERAFGVADDI LSRLDRLGED 540 541 LGTVINQMND FSKPDDSISE IVKVLNAQLA SLGWVENRIF QMEEKLDTIK KKNSDVLF 598 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCTTTCA ACCCAGGTAA TAACCAGAAT TCAGGGTTTT CATTTGGGAA ACCTGCGCAG 60 61 CCGAATTCAG CTGCGCAAGG AGCAGCAACT CCTGCGGCGA CTGGCTTGTT TGGAAACACA 120 121 AATAATAATA CCTCTTCTAC AGCGCCGTCT GGAGGCTTAT TTGGTTCTAA TAACGCGAGT 180 181 AACACCAGTG CTCCCAGTAC CTTTTCTTTT GGTAAAGCAG CGACTACAGG CAACTCAACA 240 241 AATGCATCAA CGAGTTCACC TTTTTCGTTT GGGTCTACTA ATACCAACAA TACTGCTGGG 300 301 GCTAAACCTC TTTTCGGAGG TTTAGGAAGT ACCGGGTCTG CTAACTCTAC TGGTGATAAA 360 361 AGTAAAAACA CCGCTTCTTC TGCTACAGGT GCAGCAACTA CTAATCCTTC AGGTAGTACT 420 421 TTTAATTTTG GAAGTTCAAA TAATTCTTTT AATTTCGGTA AACCCGCTTC TACGACTAAT 480 481 ACGACGACTC CGGCAGCCGC TAGTACTGGT TCTTTGTTTG GGAAGCCTGC TGCTACAGGG 540 541 ACTACAAGCA ATGCCCCTCC AGCTTCTTCT ACTTCTACGA CACCTGCTAC TGGAAGCGGA 600 601 GGTTTTAGCT TTGGAAAACC TGCTAGTTTA GGCTCTACTA ATAATGCATC CACTTCAACC 660 661 ACTGCTAATT CAGGCTTTAG CTTCGGAAAG CCTGCAACTA CTTCAGCTCC AGGATCTAAC 720 721 ACTACTGTCA CCCCCAGTAG CTCCATTACG GGAACCAATG ACTCAAAGCC TGCTGCATCT 780 781 AACACTGGTT CTGCTCCAAC TACTGGTTTC TCTTTTGGTA AGCCTGCGGG CCAAGCAGCT 840 841 TCAACCGCAA CGGACAAAGG TACTACCACC ACATCTTCAG CTGGTACTGG ATTTAGTTTT 900 901 GGAAAACCTG CAACTACAGA GGATACTAAT AAACCTACTG CTCCCAACTC AGCTTTTACA 960 961 AAACCGGCTA CTTCAACTGG TGATAATAAG CCAACATTTT CTTTTGGAAA CACTTCAAAA 1020 1021 CCTACGGAAA ATACTAGCAC AACAGCAACT TCAGCTCCGC CACTTTCGAA CAATACGAAA 1080 1081 CCTGCAGAAG GTGCGAATCA GACTAGCTCT GGATTTTCAT TTGGTAAACC TGCAACTGAT 1140 1141 ACTACAACAT CTACTTCAAA AACCGGTCCC CTTTTTGGTA ATAAACCTGC CGATCCCAGC 1200 1201 GCCAAGCCGG GCGCTACTGC CTCCACTACT CCTTCTGAGC CTCCTCCATC TTCTATCAAA 1260 1261 CACAAAACTC TTCAGGAAAT CCTTAATAAA TGGTCTACTG ATTTGACTAC GCAAACTGAA 1320 1321 GTTTTTAATA AGCTTTGTGA CCAGGTTTCT GACTGGGATA GAACTTTAGT AGACAATGGT 1380 1381 GCTTTAATAT CGAAATTATA CACTGAAACT GTTGAAGCAG AACAGATGTC AAACCGCATT 1440 1441 GATGACGGAT TGGAATATGT ATCTTCCAGC CAGCAAGAGC TATTTAAATT GCTGGATTCT 1500 1501 TATGAAACTC AGTTGGAGAC CTTTGATGGT CGTGCAACTT CAGCACTTAA CGTCGAACGT 1560 1561 GAGCGCGCTT TTGGTGTTGC TGATGATATT TTGAGTAGAT TGGATCGATT GGGTGAAGAC 1620 1621 CTTGGTACTG TCATAAACCA AATGAATGAT TTTTCTAAAC CCGATGATTC AATTTCCGAA 1680 1681 ATTGTGAAGG TTTTGAATGC ACAGTTGGCA AGTCTCGGAT GGGTTGAAAA TAGAATATTT 1740 1741 CAAATGGAAG AAAAGTTGGA TACAATAAAA AAAAAGAATT CTGACGTTTT GTTCTAA 1797 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Nuclear envelope | |
Cellular Component | Nuclear membrane | |
Cellular Component | Nuclear periphery | |
Cellular Component | Nuclear pore | |
Cellular Component | Nuclear pore central transport channel | |
Cellular Component | Nuclear pore nuclear basket | |
Molecular Function | Phospholipid binding | |
Molecular Function | Structural constituent of nuclear pore | |
Biological Process | Division septum assembly | |
Biological Process | MRNA transport | |
Biological Process | Protein import into nucleus | |
Biological Process | Regulation of G2/M transition of mitotic cell cycle | |
Biological Process | Ribosomal subunit export from nucleus |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Scc-1148 | Schizosaccharomyces cryophilus | 74.4 | 2e-112 | 354 |
| LLPS-Scj-0892 | Schizosaccharomyces japonicus | 50.67 | 7e-93 | 303 |
| LLPS-Nec-1455 | Neurospora crassa | 40.66 | 4e-36 | 147 |
| LLPS-Map-0176 | Magnaporthe poae | 40.35 | 1e-35 | 145 |
| LLPS-Gag-0455 | Gaeumannomyces graminis | 37.63 | 2e-36 | 148 |
| LLPS-Mao-0619 | Magnaporthe oryzae | 37.63 | 1e-36 | 148 |
| LLPS-Coo-0374 | Colletotrichum orbiculare | 35.6 | 8e-35 | 144 |
| LLPS-Nol-2409 | Nomascus leucogenys | 35.44 | 7e-07 | 53.9 |
| LLPS-Fec-1520 | Felis catus | 35.0 | 3e-08 | 57.4 |
| LLPS-Cog-0287 | Colletotrichum gloeosporioides | 34.95 | 1e-28 | 118 |
| LLPS-Trv-0394 | Trichoderma virens | 34.94 | 2e-25 | 109 |
| LLPS-Fuo-0560 | Fusarium oxysporum | 34.55 | 5e-35 | 144 |
| LLPS-Cogr-0156 | Colletotrichum graminicola | 34.55 | 5e-34 | 142 |
| LLPS-Asni-0901 | Aspergillus niger | 34.41 | 1e-32 | 137 |
| LLPS-Blg-0582 | Blumeria graminis | 34.25 | 4e-31 | 131 |
| LLPS-Tum-1472 | Tuber melanosporum | 34.22 | 6e-33 | 138 |
| LLPS-Fuv-1330 | Fusarium verticillioides | 34.2 | 6e-36 | 147 |
| LLPS-Gog-3950 | Gorilla gorilla | 34.18 | 9e-06 | 50.4 |
| LLPS-Fus-0426 | Fusarium solani | 34.03 | 3e-34 | 142 |
| LLPS-Trr-0482 | Trichoderma reesei | 34.03 | 1e-32 | 136 |
| LLPS-Abg-1709 | Absidia glauca | 33.87 | 3e-31 | 134 |
| LLPS-Nef-0132 | Neosartorya fischeri | 33.87 | 1e-32 | 137 |
| LLPS-Beb-0460 | Beauveria bassiana | 33.51 | 2e-31 | 134 |
| LLPS-Ved-0623 | Verticillium dahliae | 33.51 | 1e-30 | 131 |
| LLPS-Asc-0512 | Aspergillus clavatus | 33.33 | 5e-31 | 132 |
| LLPS-Yal-0689 | Yarrowia lipolytica | 33.33 | 2e-32 | 135 |
| LLPS-Asn-0265 | Aspergillus nidulans | 33.33 | 4e-32 | 135 |
| LLPS-Asf-0232 | Aspergillus flavus | 33.33 | 4e-32 | 135 |
| LLPS-Ast-0128 | Aspergillus terreus | 33.33 | 2e-32 | 136 |
| LLPS-Asfu-0109 | Aspergillus fumigatus | 33.33 | 4e-31 | 132 |
| LLPS-Pat-0245 | Pan troglodytes | 32.91 | 8e-06 | 50.4 |
| LLPS-Urm-1016 | Ursus maritimus | 32.69 | 1e-20 | 95.1 |
| LLPS-Aon-0229 | Aotus nancymaae | 32.53 | 6e-06 | 51.2 |
| LLPS-Aso-0772 | Aspergillus oryzae | 32.46 | 4e-32 | 135 |
| LLPS-Usm-0223 | Ustilago maydis | 31.96 | 6e-28 | 123 |
| LLPS-Miv-0044 | Microbotryum violaceum | 31.74 | 3e-26 | 118 |
| LLPS-Mup-0907 | Mustela putorius furo | 31.64 | 1e-24 | 112 |
| LLPS-Lac-1785 | Latimeria chalumnae | 31.29 | 5e-21 | 101 |
| LLPS-Sah-2950 | Sarcophilus harrisii | 31.21 | 6e-18 | 88.6 |
| LLPS-Mea-2050 | Mesocricetus auratus | 31.21 | 6e-24 | 109 |
| LLPS-Phn-1190 | Phaeosphaeria nodorum | 31.09 | 4e-29 | 126 |
| LLPS-Rhb-0077 | Rhinopithecus bieti | 31.08 | 2e-19 | 95.5 |
| LLPS-Meg-2546 | Meleagris gallopavo | 31.07 | 5e-24 | 109 |
| LLPS-Dar-0484 | Danio rerio | 31.07 | 2e-25 | 114 |
| LLPS-Pes-1820 | Pelodiscus sinensis | 31.07 | 1e-24 | 112 |
| LLPS-Gaga-3717 | Gallus gallus | 31.07 | 3e-25 | 114 |
| LLPS-Tut-0984 | Tursiops truncatus | 31.03 | 9e-26 | 115 |
| LLPS-Xet-1447 | Xenopus tropicalis | 30.9 | 5e-25 | 113 |
| LLPS-Cii-0689 | Ciona intestinalis | 30.77 | 1e-21 | 103 |
| LLPS-Pug-0974 | Puccinia graminis | 30.67 | 4e-28 | 123 |
| LLPS-Mum-0747 | Mus musculus | 30.64 | 1e-23 | 108 |
| LLPS-Ran-0327 | Rattus norvegicus | 30.64 | 2e-23 | 108 |
| LLPS-Sus-0036 | Sus scrofa | 30.51 | 2e-24 | 110 |
| LLPS-Chs-0230 | Chlorocebus sabaeus | 30.51 | 2e-24 | 111 |
| LLPS-Asm-0554 | Astyanax mexicanus | 30.51 | 4e-24 | 110 |
| LLPS-Bot-1002 | Bos taurus | 30.51 | 5e-25 | 113 |
| LLPS-Scf-0252 | Scleropages formosus | 30.51 | 1e-24 | 112 |
| LLPS-Dio-1550 | Dipodomys ordii | 30.51 | 2e-24 | 111 |
| LLPS-Aim-0397 | Ailuropoda melanoleuca | 30.51 | 3e-24 | 110 |
| LLPS-Myl-0457 | Myotis lucifugus | 30.51 | 6e-25 | 112 |
| LLPS-Mod-0548 | Monodelphis domestica | 30.51 | 7e-25 | 113 |
| LLPS-Hos-0447 | Homo sapiens | 30.51 | 1e-24 | 112 |
| LLPS-Orn-1555 | Oreochromis niloticus | 30.51 | 2e-24 | 111 |
| LLPS-Fia-2305 | Ficedula albicollis | 30.51 | 9e-24 | 109 |
| LLPS-Otg-0768 | Otolemur garnettii | 30.51 | 4e-25 | 113 |
| LLPS-Mam-1348 | Macaca mulatta | 30.51 | 2e-24 | 111 |
| LLPS-Eqc-0207 | Equus caballus | 30.51 | 2e-24 | 110 |
| LLPS-Poa-0210 | Pongo abelii | 30.51 | 1e-24 | 112 |
| LLPS-Caf-1627 | Canis familiaris | 30.51 | 3e-24 | 110 |
| LLPS-Anc-0486 | Anolis carolinensis | 30.51 | 8e-24 | 110 |
| LLPS-Pyt-0636 | Pyrenophora teres | 30.3 | 1e-27 | 122 |
| LLPS-Pytr-0230 | Pyrenophora triticirepentis | 30.3 | 2e-27 | 121 |
| LLPS-Dos-0104 | Dothistroma septosporum | 30.3 | 2e-25 | 115 |
| LLPS-Asg-0883 | Ashbya gossypii | 30.21 | 1e-23 | 110 |
| LLPS-Ict-0026 | Ictidomys tridecemlineatus | 30.2 | 2e-25 | 114 |
| LLPS-Kop-0287 | Komagataella pastoris | 30.16 | 4e-29 | 127 |
| LLPS-Lem-0673 | Leptosphaeria maculans | 30.05 | 8e-29 | 125 |
| LLPS-Zyt-0661 | Zymoseptoria tritici | 30.05 | 1e-24 | 112 |
| LLPS-Ora-1642 | Ornithorhynchus anatinus | 30.0 | 1e-24 | 112 |
| LLPS-Leo-0401 | Lepisosteus oculatus | 29.94 | 1e-24 | 113 |
| LLPS-Icp-0117 | Ictalurus punctatus | 29.94 | 2e-23 | 108 |
| LLPS-Tar-0530 | Takifugu rubripes | 29.94 | 5e-24 | 110 |
| LLPS-Xim-0153 | Xiphophorus maculatus | 29.94 | 3e-24 | 110 |
| LLPS-Scm-0319 | Scophthalmus maximus | 29.94 | 2e-24 | 111 |
| LLPS-Pof-1431 | Poecilia formosa | 29.94 | 4e-24 | 110 |
| LLPS-Cap-3181 | Cavia porcellus | 29.94 | 2e-24 | 111 |
| LLPS-Ten-0516 | Tetraodon nigroviridis | 29.94 | 2e-23 | 108 |
| LLPS-Tag-1604 | Taeniopygia guttata | 29.94 | 8e-23 | 105 |
| LLPS-Orl-1919 | Oryzias latipes | 29.78 | 2e-24 | 111 |
| LLPS-Loa-2470 | Loxodonta africana | 29.7 | 5e-24 | 110 |
| LLPS-Chr-1445 | Chlamydomonas reinhardtii | 29.61 | 5e-19 | 95.1 |
| LLPS-Spr-0893 | Sporisorium reilianum | 29.53 | 1e-27 | 122 |
| LLPS-Gaa-0916 | Gasterosteus aculeatus | 29.38 | 3e-23 | 108 |
| LLPS-Ova-1283 | Ovis aries | 29.06 | 2e-22 | 103 |
| LLPS-Orc-2142 | Oryctolagus cuniculus | 28.89 | 6e-11 | 67.0 |
| LLPS-Cis-0011 | Ciona savignyi | 28.65 | 3e-20 | 97.8 |
| LLPS-Sac-0267 | Saccharomyces cerevisiae | 28.5 | 3e-20 | 99.4 |
| LLPS-Maf-1559 | Macaca fascicularis | 28.49 | 5e-16 | 82.4 |
| LLPS-Pap-2429 | Pan paniscus | 28.18 | 6e-15 | 79.3 |
| LLPS-Dac-0914 | Daucus carota | 27.75 | 2e-11 | 68.6 |
| LLPS-Php-0309 | Physcomitrella patens | 27.13 | 2e-19 | 96.7 |
| LLPS-Hea-1931 | Helianthus annuus | 27.12 | 1e-12 | 72.0 |
| LLPS-Orp-1009 | Oryza punctata | 27.06 | 5e-06 | 50.8 |
| LLPS-Amt-1525 | Amborella trichopoda | 26.74 | 6e-15 | 82.4 |
| LLPS-Drm-0303 | Drosophila melanogaster | 26.7 | 1e-18 | 92.4 |
| LLPS-Chc-0099 | Chondrus crispus | 26.42 | 4e-17 | 89.4 |
| LLPS-Crn-0155 | Cryptococcus neoformans | 26.19 | 4e-23 | 108 |
| LLPS-Vir-1120 | Vigna radiata | 26.14 | 1e-11 | 68.9 |
| LLPS-Pot-0391 | Populus trichocarpa | 26.14 | 5e-15 | 82.8 |
| LLPS-Phv-1619 | Phaseolus vulgaris | 25.57 | 2e-11 | 68.2 |
| LLPS-Coc-1766 | Corchorus capsularis | 25.51 | 3e-15 | 83.2 |
| LLPS-Met-1125 | Medicago truncatula | 25.43 | 3e-12 | 71.2 |
| LLPS-Cus-0640 | Cucumis sativus | 25.26 | 6e-15 | 82.8 |
| LLPS-Thc-0444 | Theobroma cacao | 25.0 | 4e-14 | 80.1 |
| LLPS-Mua-0646 | Musa acuminata | 25.0 | 2e-14 | 80.9 |
| LLPS-Mae-2510 | Manihot esculenta | 25.0 | 9e-15 | 82.0 |
| LLPS-Orni-1461 | Oryza nivara | 24.86 | 4e-09 | 61.2 |
| LLPS-Orgl-0214 | Oryza glumaepatula | 24.86 | 5e-09 | 62.0 |
| LLPS-Orm-0081 | Oryza meridionalis | 24.86 | 9e-09 | 60.8 |
| LLPS-Org-0201 | Oryza glaberrima | 24.86 | 1e-08 | 59.7 |
| LLPS-Prp-1424 | Prunus persica | 24.74 | 9e-15 | 82.0 |
| LLPS-Via-0180 | Vigna angularis | 24.62 | 3e-16 | 86.7 |
| LLPS-Art-0858 | Arabidopsis thaliana | 24.61 | 6e-16 | 85.5 |
| LLPS-Orb-0557 | Oryza barthii | 24.54 | 5e-06 | 51.6 |
| LLPS-Arl-1726 | Arabidopsis lyrata | 24.48 | 2e-16 | 87.4 |
| LLPS-Brn-1483 | Brassica napus | 24.47 | 1e-16 | 87.8 |
| LLPS-Brr-1254 | Brassica rapa | 24.47 | 1e-16 | 87.8 |
| LLPS-Bro-0232 | Brassica oleracea | 24.47 | 6e-17 | 88.6 |
| LLPS-Sol-1010 | Solanum lycopersicum | 24.21 | 3e-15 | 83.2 |
| LLPS-Glm-1934 | Glycine max | 24.1 | 8e-16 | 85.1 |
| LLPS-Tra-1538 | Triticum aestivum | 24.08 | 5e-12 | 73.2 |
| LLPS-Viv-0213 | Vitis vinifera | 23.96 | 6e-15 | 82.4 |
| LLPS-Hov-1276 | Hordeum vulgare | 23.94 | 6e-13 | 75.9 |
| LLPS-Nia-2130 | Nicotiana attenuata | 23.7 | 4e-12 | 70.5 |
| LLPS-Gor-0582 | Gossypium raimondii | 23.63 | 1e-13 | 78.2 |
| LLPS-Sob-0678 | Sorghum bicolor | 23.53 | 2e-12 | 74.7 |
| LLPS-Brd-0944 | Brachypodium distachyon | 22.46 | 4e-12 | 73.2 |
| LLPS-Sei-0472 | Setaria italica | 22.46 | 2e-12 | 74.7 |
| LLPS-Zem-0807 | Zea mays | 22.34 | 1e-12 | 75.1 |
| LLPS-Orbr-1367 | Oryza brachyantha | 21.93 | 2e-11 | 71.2 |