• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Scm-2766
SMAX5B_020692

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: V-type proton ATPase proteolipid subunit
Gene Name: SMAX5B_020692
Ensembl Gene: ENSSMAG00000009799.1
Ensembl Protein: ENSSMAP00000015986.1
Organism: Scophthalmus maximus
Taxa ID: 52904
LLPS Type: Regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, OthersPredicted from orthologs(View)

▼ FUNCTION

Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSSQESPEYA  PFFAVMGASA  AMVFSALGAA  YGTAKSGTGI  AAMSVMRPEL  IMKSIIPVVM  60
61    AGIIAIYGLV  VAVLIANNIS  ERITLYKSFL  HLGAGLSVGL  SGLAAGFAIG  IVGDAGVRGT  120
121   AQQPRLFVGM  ILILIFAEVL  GLYGLIVALI  LSTK  154
Nucleotide CDS Sequence (FASTA)
1     ATGTCTTCCC  AGGAGAGCCC  CGAGTACGCG  CCCTTCTTCG  CCGTGATGGG  AGCCTCTGCG  60
61    GCCATGGTCT  TCAGCGCACT  AGGAGCAGCA  TACGGGACAG  CGAAGAGTGG  CACGGGGATT  120
121   GCTGCCATGT  CCGTGATGCG  GCCAGAGCTC  ATCATGAAGT  CCATCATCCC  CGTGGTCATG  180
181   GCAGGAATCA  TCGCCATCTA  CGGCCTAGTG  GTGGCTGTGC  TGATAGCAAA  CAACATTTCT  240
241   GAGAGAATCA  CCCTTTACAA  GAGTTTCCTG  CATCTTGGTG  CCGGTCTGAG  CGTGGGCCTG  300
301   AGCGGTCTGG  CAGCCGGGTT  CGCCATCGGA  ATTGTGGGCG  ACGCTGGCGT  TCGGGGCACT  360
361   GCCCAGCAGC  CCCGGCTTTT  TGTGGGCATG  ATCTTGATCC  TGATCTTCGC  CGAGGTGCTG  420
421   GGGCTTTATG  GCCTCATCGT  GGCCCTCATC  CTATCTACAA  AATAA  465

▼ KEYWORD

ID
Family
Complete proteome
Hydrogen ion transport
Ion transport
Membrane
Reference proteome
Transmembrane
Transmembrane helix
Transport
Vacuole

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Integral component of membrane
Cellular Component
Proton-transporting V-type ATPase, V0 domain
Cellular Component
Vacuolar membrane
Molecular Function
Proton transmembrane transporter activity
Biological Process
ATP hydrolysis coupled proton transport

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pof-0394Poecilia formosa97.42e-82 246
LLPS-Orn-1421Oreochromis niloticus97.42e-82 246
LLPS-Orl-1461Oryzias latipes97.42e-82 246
LLPS-Xim-2375Xiphophorus maculatus97.42e-82 246
LLPS-Asm-1018Astyanax mexicanus97.371e-80 242
LLPS-Gaa-0205Gasterosteus aculeatus97.372e-80 241
LLPS-Tar-3188Takifugu rubripes96.754e-82 246
LLPS-Ten-2137Tetraodon nigroviridis96.134e-80 241
LLPS-Scf-0752Scleropages formosus96.055e-79 238
LLPS-Tag-2524Taeniopygia guttata95.353e-60 189
LLPS-Poa-1213Pongo abelii95.312e-60 190
LLPS-Loa-2582Loxodonta africana95.274e-75 228
LLPS-Leo-1147Lepisosteus oculatus94.748e-78 235
LLPS-Icp-2464Ictalurus punctatus94.746e-77 233
LLPS-Pes-0080Pelodiscus sinensis94.571e-59 188
LLPS-Sah-2120Sarcophilus harrisii94.044e-73 226
LLPS-Myl-2840Myotis lucifugus93.927e-74 225
LLPS-Maf-3594Macaca fascicularis93.758e-60 188
LLPS-Dio-1293Dipodomys ordii93.752e-48 159
LLPS-Mal-1174Mandrillus leucophaeus93.758e-60 188
LLPS-Gaga-0465Gallus gallus93.515e-76 230
LLPS-Anc-2391Anolis carolinensis93.462e-76 231
LLPS-Lac-3136Latimeria chalumnae93.424e-76 230
LLPS-Bot-1559Bos taurus92.911e-57 184
LLPS-Pat-0623Pan troglodytes92.762e-75 229
LLPS-Pap-3834Pan paniscus92.762e-75 229
LLPS-Dar-2955Danio rerio92.761e-76 232
LLPS-Nol-3873Nomascus leucogenys92.762e-75 229
LLPS-Gog-3016Gorilla gorilla92.762e-75 229
LLPS-Caj-3741Callithrix jacchus92.768e-76 229
LLPS-Mod-3833Monodelphis domestica92.723e-73 224
LLPS-Sus-0918Sus scrofa92.164e-75 228
LLPS-Hos-3436Homo sapiens92.112e-74 226
LLPS-Fec-2167Felis catus92.111e-74 227
LLPS-Man-1439Macaca nemestrina92.116e-75 228
LLPS-Rhb-3112Rhinopithecus bieti92.115e-75 228
LLPS-Cas-1003Carlito syrichta92.115e-75 228
LLPS-Chs-3099Chlorocebus sabaeus92.116e-75 228
LLPS-Cea-0440Cercocebus atys92.116e-75 228
LLPS-Aon-4245Aotus nancymaae92.114e-75 228
LLPS-Paa-0874Papio anubis92.116e-75 228
LLPS-Meg-0712Meleagris gallopavo92.037e-62 194
LLPS-Mup-3077Mustela putorius furo92.06e-72 220
LLPS-Urm-0889Ursus maritimus91.454e-74 225
LLPS-Otg-2052Otolemur garnettii91.452e-74 226
LLPS-Eqc-4105Equus caballus91.452e-74 226
LLPS-Tut-1399Tursiops truncatus91.454e-74 225
LLPS-Aim-0301Ailuropoda melanoleuca91.333e-71 219
LLPS-Caf-0359Canis familiaris90.854e-74 225
LLPS-Cap-4090Cavia porcellus90.854e-74 225
LLPS-Xet-1753Xenopus tropicalis90.852e-74 226
LLPS-Ict-1235Ictidomys tridecemlineatus90.792e-74 226
LLPS-Fud-2147Fukomys damarensis90.132e-72 221
LLPS-Mum-3825Mus musculus90.073e-73 223
LLPS-Ran-0944Rattus norvegicus90.073e-73 223
LLPS-Orc-2243Oryctolagus cuniculus87.31e-29 109
LLPS-Anp-1785Anas platyrhynchos84.423e-61 192
LLPS-Drm-0803Drosophila melanogaster82.475e-65 202
LLPS-Cii-0988Ciona intestinalis79.871e-62 196
LLPS-Mam-1059Macaca mulatta78.954e-60 190
LLPS-Scp-0809Schizosaccharomyces pombe74.685e-61 192
LLPS-Crn-0290Cryptococcus neoformans74.343e-59 188
LLPS-Pug-0477Puccinia graminis74.033e-61 192
LLPS-Scc-0648Schizosaccharomyces cryophilus74.031e-60 191
LLPS-Blg-0123Blumeria graminis73.834e-59 187
LLPS-Phn-0548Phaeosphaeria nodorum73.382e-52 170
LLPS-Pyt-0619Pyrenophora teres73.151e-56 183
LLPS-Gag-1005Gaeumannomyces graminis73.084e-59 187
LLPS-Beb-0074Beauveria bassiana72.731e-61 194
LLPS-Zyt-1303Zymoseptoria tritici72.738e-61 192
LLPS-Nec-0674Neurospora crassa72.553e-58 185
LLPS-Map-0366Magnaporthe poae72.442e-58 186
LLPS-Miv-0135Microbotryum violaceum72.379e-58 184
LLPS-Scs-0063Sclerotinia sclerotiorum72.372e-59 188
LLPS-Mao-0255Magnaporthe oryzae72.261e-59 189
LLPS-Trr-1131Trichoderma reesei72.081e-60 191
LLPS-Fus-1099Fusarium solani72.081e-60 191
LLPS-Usm-0561Ustilago maydis72.081e-59 189
LLPS-Pytr-1229Pyrenophora triticirepentis72.083e-59 187
LLPS-Spr-0271Sporisorium reilianum72.082e-59 189
LLPS-Ved-1267Verticillium dahliae72.081e-60 191
LLPS-Ast-1313Aspergillus terreus71.537e-56 179
LLPS-Cog-1366Colletotrichum gloeosporioides71.432e-60 191
LLPS-Trv-0731Trichoderma virens71.434e-60 190
LLPS-Fuo-1282Fusarium oxysporum71.438e-60 189
LLPS-Dos-0730Dothistroma septosporum71.432e-60 191
LLPS-Fuv-1463Fusarium verticillioides71.438e-60 189
LLPS-Tum-1030Tuber melanosporum71.431e-58 186
LLPS-Kop-0033Komagataella pastoris71.057e-57 182
LLPS-Cogr-0550Colletotrichum graminicola70.789e-60 189
LLPS-Coo-0185Colletotrichum orbiculare70.785e-60 190
LLPS-Lem-0219Leptosphaeria maculans70.786e-59 187
LLPS-Yal-0191Yarrowia lipolytica70.593e-57 182
LLPS-Asg-1277Ashbya gossypii70.391e-55 178
LLPS-Abg-0519Absidia glauca69.745e-57 182
LLPS-Asn-0088Aspergillus nidulans69.481e-59 189
LLPS-Mel-0703Melampsora laricipopulina69.384e-57 182
LLPS-Sac-0294Saccharomyces cerevisiae69.089e-56 179
LLPS-Asf-0751Aspergillus flavus69.033e-57 185
LLPS-Aso-1399Aspergillus oryzae68.879e-57 181
LLPS-Asc-1100Aspergillus clavatus68.189e-59 186
LLPS-Cae-0097Caenorhabditis elegans68.151e-54 176
LLPS-Gas-0836Galdieria sulphuraria67.763e-51 167
LLPS-Nef-0221Neosartorya fischeri67.531e-58 186
LLPS-Asfu-0772Aspergillus fumigatus67.531e-58 186
LLPS-Asni-1468Aspergillus niger67.533e-59 188
LLPS-Osl-0840Ostreococcus lucimarinus67.112e-52 170
LLPS-Orbr-0804Oryza brachyantha66.01e-51 169
LLPS-Zem-2579Zea mays66.01e-51 168
LLPS-Tru-1407Triticum urartu66.02e-50 170
LLPS-Sei-0277Setaria italica66.02e-50 167
LLPS-Hov-1812Hordeum vulgare66.01e-51 169
LLPS-Brd-1975Brachypodium distachyon66.01e-51 168
LLPS-Tra-1325Triticum aestivum66.01e-51 168
LLPS-Cym-0019Cyanidioschyzon merolae65.587e-49 161
LLPS-Chr-1198Chlamydomonas reinhardtii65.567e-51 167
LLPS-Dac-1584Daucus carota65.331e-51 169
LLPS-Lep-1638Leersia perrieri65.333e-51 167
LLPS-Sob-0188Sorghum bicolor65.197e-52 169
LLPS-Php-1028Physcomitrella patens64.713e-51 167
LLPS-Ors-0603Oryza sativa64.675e-51 167
LLPS-Orp-1039Oryza punctata64.675e-51 167
LLPS-Orr-0423Oryza rufipogon64.675e-51 167
LLPS-Org-0008Oryza glaberrima64.675e-51 167
LLPS-Orb-0022Oryza barthii64.675e-51 167
LLPS-Ori-1191Oryza indica64.675e-51 167
LLPS-Orni-0138Oryza nivara64.675e-51 167
LLPS-Orgl-0861Oryza glumaepatula64.675e-51 167
LLPS-Cus-0683Cucumis sativus64.565e-52 169
LLPS-Pot-2719Populus trichocarpa64.15e-52 169
LLPS-Arl-0304Arabidopsis lyrata64.12e-52 171
LLPS-Sem-0685Selaginella moellendorffii64.051e-51 168
LLPS-Viv-1924Vitis vinifera63.697e-53 171
LLPS-Brr-1604Brassica rapa63.692e-52 171
LLPS-Phv-1839Phaseolus vulgaris63.698e-53 171
LLPS-Bro-2259Brassica oleracea63.693e-50 171
LLPS-Glm-0218Glycine max63.694e-52 169
LLPS-Sol-1108Solanum lycopersicum63.697e-53 171
LLPS-Brn-3242Brassica napus63.693e-50 171
LLPS-Mua-1742Musa acuminata63.697e-53 171
LLPS-Via-2379Vigna angularis63.698e-53 171
LLPS-Sot-0215Solanum tuberosum63.697e-53 171
LLPS-Gor-2239Gossypium raimondii63.465e-52 169
LLPS-Art-2067Arabidopsis thaliana63.465e-52 169
LLPS-Mae-1540Manihot esculenta63.465e-52 169
LLPS-Nia-0616Nicotiana attenuata63.463e-52 170
LLPS-Orm-1414Oryza meridionalis63.461e-51 168
LLPS-Coc-2196Corchorus capsularis63.465e-52 169
LLPS-Prp-1333Prunus persica63.464e-52 169
LLPS-Hea-0065Helianthus annuus63.465e-52 169
LLPS-Thc-2339Theobroma cacao63.465e-52 169
LLPS-Amt-0959Amborella trichopoda63.066e-52 169
LLPS-Met-1294Medicago truncatula63.067e-52 169
LLPS-Vir-1850Vigna radiata63.063e-52 170
LLPS-Scj-0348Schizosaccharomyces japonicus62.182e-46 155