• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Scf-a098
Z043_121685

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Tubulin alpha chain
Gene Name: Z043_121685
Ensembl Gene: ENSSFOG00015020851.1
Ensembl Protein: ENSSFOP00015032606.1
Organism: Scleropages formosus
Taxa ID: 113540
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granulePredicted from orthologs(View)

▼ FUNCTION


Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

▼ SEQUENCE


Protein Sequence (FASTA)
1     RCVILLLLQV  FIIFEMRSRE  CISIHVGQAG  VQIGNACWEL  YCLEHGIQPD  GQMPSDKTIG  60
61    GGDDSFNTFF  SETGAGKHVP  RAVFVDLEPT  VIDEVRTGTY  RQLFHPEQLI  TGKEDAANNY  120
121   ARGHYTIGKE  IIDLVLDRIR  KLADQCTGLQ  GFLVFHSFGG  GTGSGFTSLL  MERLSVDYGK  180
181   KSKLEFSIYP  APQVSTAVVE  PYNSILTTHT  TLEHSDCAFM  VDNEAIYDIC  RRNLDIERPT  240
241   YTNLNRLIGQ  IVSSITASLR  FDGALNVDLT  EFQTNLVPYP  RIHFPLATYA  PVISAEKAYH  300
301   EQLSVAEITN  ACFEPANQMV  KCDPRHGKYM  ACCLLYRGDV  VPKDVNAAIA  TIKTKRTIQF  360
361   VDWCPTGFKV  GINYQPPTVV  PGGDLAKVQR  AVCMLSNTTA  IAEAWARLDH  KFDLMYAKRA  420
421   FVHWYVGEGM  EEGEFSEARE  DMAALEKDYE  EVGVDSIEGE  GEEEGEEY  468

▼ KEYWORD


ID
Family
Complete proteome
Cytoplasm
Cytoskeleton
GTP-binding
Microtubule
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Microtubule
Molecular Function
GTP binding
Molecular Function
GTPase activity
Molecular Function
Structural constituent of cytoskeleton
Biological Process
Microtubule-based process