• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Scf-0595
Z043_105925

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: DNA-directed RNA polymerase subunit beta
Gene Name: Z043_105925
Ensembl Gene: ENSSFOG00015000924.1
Ensembl Protein: ENSSFOP00015001412.1
Organism: Scleropages formosus
Taxa ID: 113540
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, Nucleolus, Stress granule, OthersPredicted from orthologs(View)

▼ FUNCTION

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MMPNEARLRN  LTYSAPLYVD  ITKTIIKEGE  EQLQTQHQKT  FIGKIPIMLR  STYCLLSGLT  60
61    DRDLCELNEC  PLDPGGYFII  NGSEKVLIAQ  EKMATNTVYV  FAKKDSKYAY  TAECRSCLEN  120
121   SSRPTSSIWV  SMMARGGQGV  KKSAIGQRIV  STLPYIRQEV  PIIIVFRALG  FVSDRDILEH  180
181   IIYDFDDPEM  MEMVKPSLDE  AFVIQEQNVA  LNFIGSRGAK  PGVTKEKRIK  YAKEVLQKEV  240
241   LPHVGVSDFC  ETKKAYFLGY  MVHRLLLAAL  GRRELDDRDH  YGNKRLDLAG  PLLAFLFRGM  300
301   FKNLLKEIRI  YAQKFIDRGK  DFNLELAIKT  RIISDGLKYS  LATGNWGDVK  KAHQARAGVS  360
361   QVLNRLTFAS  TLSHLRRVNS  PIGRDGKLAK  PRQLHNTLWG  MVCPAETPEG  HAVGLVKNLA  420
421   LMAYISVGSQ  PSPILEFLEE  WSMENLEEIS  PAAIADATKI  FVNGCWVGIH  KDPEQLMNTL  480
481   RKLRRQMDII  VSEVSMIRDI  REREIRIYTD  AGRICRPLLI  VEKQKLLLKR  RHIDQLKERE  540
541   YNNYSWQDLV  ASGVVEYIDT  LEEETVMLAM  TPDDLQEKGV  AYCSTYTHCE  IHPSMILGVC  600
601   ASIIPFPDHN  QSPRNTYQSA  MGKQAMGVYI  TNFHVRMDTL  AHVLYYPQKP  LVTTRSMEYL  660
661   RFRELPAGIN  SIVAIASYTG  YNQEDSVIMN  RSAVDRGFFR  SVFYRSYKEQ  ESKKGFDQEE  720
721   IFEKPSRETC  QGMRHAIYDK  LDDDGLIAPG  VRVSGEDVII  GKTVTLPEND  DELDSTNKRY  780
781   TKRDCSTFLR  TSETGIVDQV  MVTLNQEGYK  FCKIRVSVNT  QTEWYKFASR  HGQKGTCGIQ  840
841   YRQEDMPFTC  EGITPDIIIN  PHAIPSRMTV  GHLIECLQGK  VSANKGEIGD  ATPFNDAVNV  900
901   QKVSNLLAEY  GYHLRGNEVL  YNGFTGRKLT  SQIFIGPTYY  QRLKHMVDDK  IHSRARGPVQ  960
961   ILNRQPMEGR  SRDGGLRFGE  MERDCQIAHG  AAQFLRERLF  EASDPYQVHV  CNLCGLMAIA  1020
1021  NTRTHTYECR  GCRNKTQISL  VRMPYACKLL  FQELMSMSIA  PRMMTS  1066
Nucleotide CDS Sequence (FASTA)
1     ATGATGCCCA  ATGAAGCCCG  ACTCCGAAAT  CTAACGTACT  CTGCCCCACT  GTATGTGGAT  60
61    ATCACCAAAA  CTATCATCAA  AGAGGGGGAG  GAGCAACTGC  AGACACAGCA  CCAGAAAACC  120
121   TTCATTGGCA  AAATTCCCAT  CATGCTTCGC  TCCACATACT  GCCTGCTGAG  TGGTCTGACA  180
181   GATCGTGATC  TTTGTGAGCT  GAATGAGTGT  CCTCTGGACC  CTGGGGGTTA  CTTTATCATC  240
241   AATGGCTCAG  AGAAGGTGCT  CATTGCTCAG  GAGAAGATGG  CTACAAACAC  AGTGTATGTG  300
301   TTTGCCAAGA  AGGACTCCAA  GTATGCATAC  ACGGCCGAGT  GTCGCTCCTG  CCTGGAGAAC  360
361   TCATCTCGTC  CCACCAGCTC  AATCTGGGTC  AGCATGATGG  CCAGGGGTGG  ACAGGGGGTG  420
421   AAAAAGAGTG  CTATTGGCCA  AAGGATTGTC  TCCACACTCC  CCTACATTAG  GCAGGAAGTC  480
481   CCCATCATCA  TTGTGTTTCG  TGCTCTGGGC  TTTGTGTCTG  ACAGAGACAT  TCTCGAACAC  540
541   ATAATCTATG  ACTTTGATGA  CCCTGAGATG  ATGGAAATGG  TGAAGCCTTC  TTTGGATGAA  600
601   GCCTTTGTGA  TTCAAGAGCA  GAATGTGGCA  TTAAACTTCA  TTGGATCAAG  AGGTGCCAAG  660
661   CCAGGTGTTA  CCAAGGAGAA  GAGAATCAAG  TATGCCAAAG  AGGTGTTGCA  AAAGGAGGTG  720
721   CTGCCCCATG  TGGGGGTCAG  TGATTTCTGT  GAGACTAAGA  AGGCCTACTT  TTTGGGCTAC  780
781   ATGGTACACA  GACTCCTTCT  GGCTGCTCTG  GGCAGACGAG  AACTAGATGA  CAGGGATCAC  840
841   TATGGTAACA  AGAGGCTTGA  CCTGGCTGGT  CCTCTGCTGG  CCTTCTTGTT  CCGTGGAATG  900
901   TTTAAAAATC  TGTTGAAGGA  GATTAGAATA  TATGCCCAGA  AGTTCATTGA  CAGAGGGAAA  960
961   GATTTCAATT  TGGAGTTGGC  CATCAAGACG  CGCATAATTT  CTGATGGGCT  GAAGTACTCA  1020
1021  CTTGCTACTG  GGAACTGGGG  AGACGTTAAG  AAGGCTCATC  AGGCCAGAGC  TGGGGTGTCA  1080
1081  CAGGTATTGA  ACCGCTTGAC  CTTTGCCTCT  ACACTCTCCC  ACCTGCGGCG  AGTCAACTCC  1140
1141  CCCATTGGAA  GAGACGGCAA  ACTGGCAAAA  CCCAGGCAGC  TGCACAACAC  ACTGTGGGGC  1200
1201  ATGGTGTGTC  CCGCAGAGAC  CCCTGAGGGT  CATGCTGTCG  GGTTGGTGAA  GAACCTGGCA  1260
1261  CTCATGGCGT  ATATTTCCGT  TGGCTCTCAG  CCATCCCCCA  TATTGGAGTT  CTTAGAAGAG  1320
1321  TGGAGCATGG  AGAATCTGGA  GGAAATTTCT  CCTGCAGCCA  TTGCAGATGC  CACCAAGATT  1380
1381  TTTGTTAATG  GCTGCTGGGT  GGGGATCCAC  AAGGACCCAG  AACAGTTGAT  GAATACACTG  1440
1441  AGGAAGTTGA  GGAGGCAGAT  GGACATCATT  GTGTCTGAGG  TGTCGATGAT  CCGAGACATC  1500
1501  AGGGAGAGAG  AGATCCGGAT  CTATACAGAC  GCTGGGAGGA  TCTGCCGCCC  TCTGTTGATT  1560
1561  GTGGAGAAGC  AAAAGCTACT  GCTGAAGAGG  CGGCACATCG  ACCAGCTGAA  GGAAAGGGAG  1620
1621  TACAACAACT  ACAGTTGGCA  AGATCTGGTG  GCCAGTGGGG  TGGTGGAGTA  CATTGACACA  1680
1681  CTAGAGGAGG  AGACTGTGAT  GCTGGCCATG  ACCCCAGATG  ACCTGCAGGA  GAAGGGTGTG  1740
1741  GCCTATTGTT  CCACATACAC  CCACTGTGAG  ATTCACCCTT  CCATGATTTT  GGGTGTCTGT  1800
1801  GCTTCCATCA  TTCCTTTCCC  TGATCACAAT  CAGTCACCCA  GAAACACATA  CCAGTCGGCT  1860
1861  ATGGGTAAAC  AAGCTATGGG  GGTGTACATC  ACCAACTTCC  ACGTACGCAT  GGACACCCTG  1920
1921  GCCCATGTGC  TTTACTACCC  CCAAAAGCCC  CTGGTGACCA  CGCGCTCCAT  GGAATACTTG  1980
1981  CGATTCCGAG  AGTTGCCAGC  AGGCATCAAT  TCCATTGTGG  CAATTGCATC  ATACACTGGG  2040
2041  TACAATCAGG  AGGACTCTGT  TATCATGAAC  CGCTCTGCTG  TGGACCGTGG  ATTTTTCAGG  2100
2101  TCTGTGTTCT  ACAGATCATA  TAAAGAACAG  GAATCTAAGA  AAGGCTTTGA  TCAGGAGGAG  2160
2161  ATATTTGAAA  AACCCTCACG  TGAGACTTGT  CAGGGAATGC  GACATGCCAT  CTACGACAAG  2220
2221  CTAGATGACG  ATGGGCTCAT  CGCACCAGGT  GTGCGCGTGT  CTGGTGAGGA  TGTCATCATC  2280
2281  GGGAAGACTG  TGACACTTCC  AGAAAATGAT  GATGAGCTGG  ATAGTACAAA  CAAACGCTAT  2340
2341  ACCAAGCGAG  ACTGCAGCAC  TTTCCTACGT  ACCAGTGAGA  CTGGCATTGT  GGATCAGGTC  2400
2401  ATGGTCACGC  TCAACCAGGA  GGGGTACAAG  TTCTGCAAGA  TCAGAGTGAG  TGTCAACACA  2460
2461  CAGACTGAAT  GGTACAAGTT  TGCCAGTCGA  CATGGACAAA  AGGGTACCTG  TGGTATCCAG  2520
2521  TACAGGCAAG  AGGACATGCC  CTTTACATGT  GAAGGAATTA  CTCCTGATAT  CATCATTAAC  2580
2581  CCCCATGCCA  TCCCTTCTCG  AATGACAGTC  GGCCATTTGA  TCGAGTGTCT  GCAGGGCAAG  2640
2641  GTATCGGCAA  ACAAAGGGGA  AATTGGTGAT  GCCACACCTT  TCAATGATGC  TGTGAACGTG  2700
2701  CAGAAGGTCT  CTAACCTGCT  GGCTGAATAT  GGGTATCACC  TGAGGGGTAA  TGAGGTGTTA  2760
2761  TATAACGGGT  TCACGGGTCG  TAAGCTCACC  TCACAGATCT  TCATTGGGCC  CACATACTAC  2820
2821  CAGCGTTTGA  AACACATGGT  GGATGACAAG  ATCCACTCTC  GGGCCCGCGG  GCCAGTCCAG  2880
2881  ATCCTCAACA  GACAGCCTAT  GGAGGGTAGA  TCTCGTGATG  GAGGGCTACG  TTTCGGCGAG  2940
2941  ATGGAACGTG  ACTGTCAGAT  TGCTCATGGA  GCTGCCCAGT  TCCTGCGGGA  GAGGCTGTTT  3000
3001  GAGGCCTCCG  ATCCATACCA  GGTTCATGTG  TGCAACCTGT  GTGGCCTGAT  GGCCATTGCC  3060
3061  AACACCCGCA  CACACACCTA  CGAGTGCAGG  GGCTGCCGCA  ACAAAACACA  GATCTCCTTG  3120
3121  GTCAGGATGC  CCTACGCCTG  CAAGCTTCTC  TTCCAGGAAC  TGATGTCTAT  GAGCATCGCC  3180
3181  CCACGTATGA  TGACCAGTTA  A  3201

▼ KEYWORD

ID
Family
Complete proteome
DNA-directed RNA polymerase
Nucleotidyltransferase
Reference proteome
Transcription
Transferase

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
DNA binding
Molecular Function
DNA-directed 5'-3' RNA polymerase activity
Molecular Function
Ribonucleoside binding
Biological Process
Transcription, DNA-templated

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Leo-2081Lepisosteus oculatus98.60.02126
LLPS-Orn-0863Oreochromis niloticus98.590.02130
LLPS-Xim-2051Xiphophorus maculatus98.50.02128
LLPS-Orl-0952Oryzias latipes98.50.02129
LLPS-Pof-0911Poecilia formosa98.50.02128
LLPS-Dar-1201Danio rerio98.310.02125
LLPS-Icp-1747Ictalurus punctatus98.130.02120
LLPS-Ten-0037Tetraodon nigroviridis98.030.02121
LLPS-Tar-1168Takifugu rubripes97.860.01947
LLPS-Ora-1219Ornithorhynchus anatinus97.680.01436
LLPS-Pes-0236Pelodiscus sinensis97.650.01332
LLPS-Asm-1675Astyanax mexicanus97.280.02093
LLPS-Lac-0819Latimeria chalumnae96.90.02105
LLPS-Gaa-0854Gasterosteus aculeatus96.740.02088
LLPS-Loa-0401Loxodonta africana96.660.01822
LLPS-Sah-2344Sarcophilus harrisii96.620.02102
LLPS-Mod-2204Monodelphis domestica96.620.02103
LLPS-Ran-0780Rattus norvegicus96.530.02100
LLPS-Mal-1449Mandrillus leucophaeus96.530.02098
LLPS-Paa-0879Papio anubis96.530.02100
LLPS-Gog-0424Gorilla gorilla96.530.02100
LLPS-Caj-2134Callithrix jacchus96.530.02100
LLPS-Chs-0259Chlorocebus sabaeus96.530.02098
LLPS-Mea-0529Mesocricetus auratus96.530.02098
LLPS-Maf-0524Macaca fascicularis96.530.02100
LLPS-Cea-1054Cercocebus atys96.530.02100
LLPS-Aon-0108Aotus nancymaae96.530.02100
LLPS-Cas-0015Carlito syrichta96.530.02100
LLPS-Ict-1999Ictidomys tridecemlineatus96.530.02100
LLPS-Eqc-1211Equus caballus96.530.02100
LLPS-Cap-0012Cavia porcellus96.530.02100
LLPS-Poa-0478Pongo abelii96.530.02100
LLPS-Mam-1023Macaca mulatta96.530.02100
LLPS-Otg-0159Otolemur garnettii96.530.02100
LLPS-Pap-0170Pan paniscus96.530.02100
LLPS-Pat-0085Pan troglodytes96.530.02100
LLPS-Hos-1601Homo sapiens96.530.02100
LLPS-Man-2654Macaca nemestrina96.530.02100
LLPS-Ova-0493Ovis aries96.440.02098
LLPS-Mup-0974Mustela putorius furo96.440.02098
LLPS-Bot-3252Bos taurus96.440.02098
LLPS-Fud-0561Fukomys damarensis96.440.02098
LLPS-Mum-0362Mus musculus96.440.02098
LLPS-Sus-2246Sus scrofa96.440.02095
LLPS-Caf-2712Canis familiaris96.440.02098
LLPS-Orc-0498Oryctolagus cuniculus96.440.02098
LLPS-Fec-1559Felis catus96.440.02098
LLPS-Myl-0364Myotis lucifugus96.340.02093
LLPS-Gaga-0412Gallus gallus96.340.02100
LLPS-Tag-1910Taeniopygia guttata96.340.02100
LLPS-Fia-1186Ficedula albicollis96.340.02098
LLPS-Aim-0426Ailuropoda melanoleuca96.250.02094
LLPS-Anp-1453Anas platyrhynchos96.250.02093
LLPS-Anc-0918Anolis carolinensis96.150.02098
LLPS-Tut-0112Tursiops truncatus95.510.02068
LLPS-Nol-2259Nomascus leucogenys95.310.02047
LLPS-Urm-0509Ursus maritimus94.470.02039
LLPS-Rhb-0164Rhinopithecus bieti94.380.02038
LLPS-Meg-0446Meleagris gallopavo93.250.02012
LLPS-Xet-1228Xenopus tropicalis93.010.02011
LLPS-Dio-0101Dipodomys ordii90.430.01930
LLPS-Cis-0440Ciona savignyi88.880.01456
LLPS-Cii-1947Ciona intestinalis86.910.01933
LLPS-Drm-1091Drosophila melanogaster85.960.01892
LLPS-Cae-0094Caenorhabditis elegans78.910.01757
LLPS-Mae-0061Manihot esculenta67.940.01448
LLPS-Gor-0480Gossypium raimondii67.940.01445
LLPS-Ori-0682Oryza indica67.910.01474
LLPS-Org-1524Oryza glaberrima67.910.01474
LLPS-Thc-0404Theobroma cacao67.840.01444
LLPS-Orp-0151Oryza punctata67.810.01473
LLPS-Amt-0160Amborella trichopoda67.720.01467
LLPS-Prp-0181Prunus persica67.660.01459
LLPS-Phv-0198Phaseolus vulgaris67.660.01455
LLPS-Viv-0403Vitis vinifera67.660.01462
LLPS-Cus-0573Cucumis sativus67.570.01445
LLPS-Coc-0183Corchorus capsularis67.570.01437
LLPS-Orbr-0147Oryza brachyantha67.570.01470
LLPS-Glm-0311Glycine max67.470.01456
LLPS-Brd-0431Brachypodium distachyon67.440.01471
LLPS-Tra-0497Triticum aestivum67.440.01471
LLPS-Hov-0457Hordeum vulgare67.440.01468
LLPS-Via-0598Vigna angularis67.380.01454
LLPS-Orgl-0087Oryza glumaepatula67.350.01450
LLPS-Orni-1680Oryza nivara67.350.01450
LLPS-Orb-0553Oryza barthii67.350.01450
LLPS-Met-0438Medicago truncatula67.290.01453
LLPS-Orm-0008Oryza meridionalis67.290.01444
LLPS-Php-0064Physcomitrella patens67.260.01459
LLPS-Orr-0891Oryza rufipogon67.260.01446
LLPS-Arl-2235Arabidopsis lyrata67.190.01430
LLPS-Art-0863Arabidopsis thaliana67.190.01429
LLPS-Brr-0612Brassica rapa67.190.01429
LLPS-Sem-1490Selaginella moellendorffii67.160.01457
LLPS-Zem-1908Zea mays67.160.01463
LLPS-Sob-0216Sorghum bicolor67.160.01458
LLPS-Bro-0917Brassica oleracea67.10.01429
LLPS-Sei-1592Setaria italica67.070.01462
LLPS-Sot-0316Solanum tuberosum66.820.01438
LLPS-Hea-1304Helianthus annuus66.730.01425
LLPS-Sol-0338Solanum lycopersicum66.730.01437
LLPS-Nia-0565Nicotiana attenuata66.730.01439
LLPS-Dac-0030Daucus carota66.640.01435
LLPS-Pot-1066Populus trichocarpa66.510.01431
LLPS-Lep-0037Leersia perrieri66.360.01439
LLPS-Vir-1546Vigna radiata66.080.01410
LLPS-Osl-0134Ostreococcus lucimarinus66.020.01431
LLPS-Brn-0367Brassica napus65.620.01384
LLPS-Mua-1023Musa acuminata64.920.01436
LLPS-Tru-0562Triticum urartu64.650.01381
LLPS-Abg-0321Absidia glauca64.320.01429
LLPS-Miv-0140Microbotryum violaceum62.920.01373
LLPS-Scj-0710Schizosaccharomyces japonicus61.610.01374
LLPS-Mel-0342Melampsora laricipopulina61.610.01368
LLPS-Scp-0489Schizosaccharomyces pombe60.990.01360
LLPS-Scc-0190Schizosaccharomyces cryophilus60.810.01364
LLPS-Pug-0048Puccinia graminis60.710.01344
LLPS-Chr-0302Chlamydomonas reinhardtii60.360.01165
LLPS-Gas-0406Galdieria sulphuraria59.890.01306
LLPS-Yal-0263Yarrowia lipolytica59.590.01308
LLPS-Sac-0104Saccharomyces cerevisiae59.410.01306
LLPS-Kop-0047Komagataella pastoris59.330.01308
LLPS-Asg-0551Ashbya gossypii59.070.01308
LLPS-Put-0236Puccinia triticina58.90.0 841
LLPS-Usm-0274Ustilago maydis58.250.01286
LLPS-Spr-0915Sporisorium reilianum58.020.01277
LLPS-Ast-0275Aspergillus terreus57.940.01284
LLPS-Asfu-0076Aspergillus fumigatus57.640.01282
LLPS-Nef-0669Neosartorya fischeri57.640.01281
LLPS-Asni-0614Aspergillus niger57.590.01279
LLPS-Blg-0398Blumeria graminis57.340.01296
LLPS-Crn-0312Cryptococcus neoformans57.330.01233
LLPS-Asf-0140Aspergillus flavus57.310.01283
LLPS-Aso-0335Aspergillus oryzae57.310.01283
LLPS-Asc-0886Aspergillus clavatus57.280.01276
LLPS-Asn-0219Aspergillus nidulans57.180.01267
LLPS-Chc-0240Chondrus crispus56.790.01223
LLPS-Coo-0607Colletotrichum orbiculare56.570.01270
LLPS-Dos-0443Dothistroma septosporum56.470.01260
LLPS-Cogr-0746Colletotrichum graminicola56.450.01268
LLPS-Nec-0212Neurospora crassa56.150.01248
LLPS-Scs-0026Sclerotinia sclerotiorum56.060.01271
LLPS-Cog-0712Colletotrichum gloeosporioides55.870.01256
LLPS-Trr-0133Trichoderma reesei55.780.01251
LLPS-Zyt-0543Zymoseptoria tritici55.720.01248
LLPS-Ved-0140Verticillium dahliae55.610.01249
LLPS-Fuv-0377Fusarium verticillioides55.590.01266
LLPS-Fuo-0662Fusarium oxysporum55.590.01267
LLPS-Beb-0210Beauveria bassiana55.570.01249
LLPS-Fus-0516Fusarium solani55.480.01249
LLPS-Trv-0401Trichoderma virens55.430.01248
LLPS-Pytr-0693Pyrenophora triticirepentis55.420.01184
LLPS-Pyt-1038Pyrenophora teres55.370.01243
LLPS-Cym-0057Cyanidioschyzon merolae55.290.01177
LLPS-Map-0413Magnaporthe poae55.280.01219
LLPS-Gag-0136Gaeumannomyces graminis55.190.01221
LLPS-Lem-0381Leptosphaeria maculans55.130.01235
LLPS-Mao-0030Magnaporthe oryzae54.840.01219
LLPS-Phn-0145Phaeosphaeria nodorum54.70.01219
LLPS-Scm-3600Scophthalmus maximus39.580.0 714
LLPS-Ors-1045Oryza sativa38.260.0 704