LLPS-Scc-1018
MET3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Sulfate adenylyltransferase; ATP-sulfurylase; Sulfate adenylate transferase; SAT |
| Gene Name: | MET3, SPOG_04466 |
| Ensembl Gene: | SPOG_04466 |
| Ensembl Protein: | EPY49178 |
| Organism: | Schizosaccharomyces cryophilus |
| Taxa ID: | 653667 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | EPY49178 | EPY49178 |
| UniProt | S9VMJ9, S9VMJ9_SCHCR | |
| GeneBank | KE546996 | EPY49178.1 |
| RefSeq | XM_013170544.1 | XP_013025998.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSQTVFKDIF ARDAPFREQL NKEAASLQKI ILTERQFCDL ELILNGGFSP LEGFMTEEDY 60 61 LSVVNNLRLK SGAVFPIPVT LDVSESQAGA INASERIALL DPRDEQTILA ILTVEDKYVP 120 121 DKVVEAEKVF GANDRAHPAV EYLFGTAGNV YLGGKLQAVN PIRHFDFVAY RYTPAELRSE 180 181 FERNNWNRVV AFQTRNPMHR AHRELTVRAA KQHSARVLIH PVVGMTKPGD IDHFTRVRVY 240 241 EAILQRYPKG SAKLSLLPLA MRMAGPREAL WHAIIRKNYG ASHFIIGRDH AGPGKNSQGK 300 301 DFYGPYDAQY LVEQYSHEIG ISIVPFQMMT YLPDEDIYKP VDQVEPGTRT LNISGTELRR 360 361 RLLVGAHIPE WFSYPQVVSI LRQSYPPKYA QGFVLAVPAT ADKLVPSALI SALNEDGRRH 420 421 VTSVSRLDTT SLTYAQELQR AGAAVVVSLA DADKSIQIPA NWVQVNIDPH ETVSEVTFTV 480 481 LSQLSDEGYL 490 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGTCAAA CTGTCTTCAA AGATATTTTT GCTAGAGACG CTCCTTTTCG TGAGCAACTC 60 61 AACAAGGAAG CAGCATCTTT GCAAAAGATT ATTTTAACGG AACGCCAATT TTGCGATCTT 120 121 GAGCTTATTT TAAATGGTGG TTTCAGTCCT TTGGAAGGAT TTATGACTGA AGAGGACTAT 180 181 CTAAGTGTCG TAAATAACTT GCGCTTGAAG TCCGGCGCAG TATTCCCTAT TCCCGTTACC 240 241 CTCGATGTTA GTGAGAGCCA AGCCGGTGCC ATTAATGCTT CAGAGCGTAT TGCTCTTTTG 300 301 GATCCTAGAG ATGAACAGAC GATTCTTGCT ATCCTCACCG TTGAAGACAA GTATGTTCCC 360 361 GATAAGGTTG TCGAGGCTGA GAAGGTTTTT GGCGCTAATG ACCGCGCGCA TCCTGCAGTA 420 421 GAATACTTGT TTGGGACTGC TGGTAATGTT TATCTTGGTG GTAAGCTTCA AGCCGTTAAC 480 481 CCTATACGCC ATTTTGATTT CGTTGCCTAC CGCTATACCC CTGCTGAGCT CCGTTCTGAA 540 541 TTTGAGCGTA ATAATTGGAA CCGTGTTGTT GCTTTCCAAA CTCGTAATCC TATGCACCGT 600 601 GCTCACCGTG AGCTTACTGT ACGTGCCGCT AAGCAACACT CTGCTCGTGT GTTGATCCAT 660 661 CCAGTTGTTG GTATGACCAA GCCAGGTGAT ATTGACCACT TCACCCGTGT TCGTGTTTAC 720 721 GAAGCTATTC TTCAACGCTA CCCCAAGGGT TCCGCTAAAC TTTCTCTTCT TCCATTAGCT 780 781 ATGCGTATGG CTGGTCCTCG GGAGGCCTTA TGGCATGCCA TCATTCGCAA GAACTATGGC 840 841 GCTAGCCATT TCATTATTGG ACGTGACCAT GCTGGTCCTG GAAAGAACAG TCAAGGCAAA 900 901 GACTTTTATG GCCCTTATGA CGCGCAATAC TTGGTTGAGC AATACTCTCA CGAAATTGGA 960 961 ATCAGCATTG TTCCTTTCCA AATGATGACT TATTTGCCTG ATGAGGACAT CTACAAGCCC 1020 1021 GTCGATCAAG TTGAACCCGG TACTCGCACT CTAAACATTA GTGGTACTGA ACTTCGTCGT 1080 1081 CGCCTTCTCG TAGGTGCTCA TATTCCTGAG TGGTTTTCTT ACCCTCAAGT TGTATCCATC 1140 1141 TTGCGTCAAT CTTATCCTCC TAAATATGCT CAGGGTTTTG TTTTGGCCGT TCCTGCTACT 1200 1201 GCAGATAAGC TCGTCCCTAG TGCCTTGATT TCTGCTCTCA ATGAAGATGG TCGTCGTCAC 1260 1261 GTAACTTCTG TCTCCCGTTT GGACACTACT TCCTTAACTT ACGCTCAGGA ACTTCAACGT 1320 1321 GCTGGTGCTG CCGTCGTTGT TTCTTTGGCT GATGCTGATA AGTCAATTCA AATCCCAGCT 1380 1381 AATTGGGTTC AAGTGAACAT TGATCCCCAT GAAACCGTAT CCGAAGTCAC TTTTACTGTT 1440 1441 CTTTCTCAAT TGTCAGATGA GGGCTATTTG TAA 1473 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | Sulfate adenylyltransferase (ATP) activity | |
Biological Process | Cysteine biosynthetic process | |
Biological Process | Hydrogen sulfide biosynthetic process | |
Biological Process | Methionine biosynthetic process | |
Biological Process | Sulfate assimilation via adenylyl sulfate reduction | |
Biological Process | Sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Scp-1202 | Schizosaccharomyces pombe | 83.27 | 0.0 | 872 |
| LLPS-Scj-0934 | Schizosaccharomyces japonicus | 74.03 | 0.0 | 747 |
| LLPS-Gag-1628 | Gaeumannomyces graminis | 64.54 | 0.0 | 558 |
| LLPS-Mao-0596 | Magnaporthe oryzae | 64.07 | 0.0 | 559 |
| LLPS-Nec-1190 | Neurospora crassa | 63.59 | 0.0 | 557 |
| LLPS-Scs-0827 | Sclerotinia sclerotiorum | 62.41 | 0.0 | 550 |
| LLPS-Kop-0885 | Komagataella pastoris | 62.31 | 0.0 | 573 |
| LLPS-Phn-0405 | Phaeosphaeria nodorum | 62.17 | 0.0 | 549 |
| LLPS-Usm-0560 | Ustilago maydis | 62.17 | 0.0 | 555 |
| LLPS-Asn-0395 | Aspergillus nidulans | 61.79 | 5e-178 | 520 |
| LLPS-Dos-1223 | Dothistroma septosporum | 60.99 | 0.0 | 540 |
| LLPS-Fuv-0066 | Fusarium verticillioides | 60.99 | 4e-178 | 520 |
| LLPS-Fuo-1307 | Fusarium oxysporum | 60.76 | 1e-177 | 518 |
| LLPS-Tum-1584 | Tuber melanosporum | 60.76 | 4e-180 | 524 |
| LLPS-Cogr-0361 | Colletotrichum graminicola | 60.52 | 4e-177 | 517 |
| LLPS-Asni-1140 | Aspergillus niger | 60.52 | 0.0 | 530 |
| LLPS-Ast-0825 | Aspergillus terreus | 60.28 | 0.0 | 530 |
| LLPS-Aso-1114 | Aspergillus oryzae | 60.28 | 1e-177 | 518 |
| LLPS-Coo-1256 | Colletotrichum orbiculare | 60.28 | 1e-175 | 513 |
| LLPS-Asc-1397 | Aspergillus clavatus | 60.28 | 0.0 | 531 |
| LLPS-Spr-1343 | Sporisorium reilianum | 60.05 | 0.0 | 544 |
| LLPS-Fus-1535 | Fusarium solani | 60.05 | 1e-175 | 513 |
| LLPS-Asg-1332 | Ashbya gossypii | 60.05 | 0.0 | 528 |
| LLPS-Trv-1599 | Trichoderma virens | 59.81 | 1e-175 | 513 |
| LLPS-Beb-1064 | Beauveria bassiana | 59.81 | 2e-178 | 521 |
| LLPS-Zyt-0437 | Zymoseptoria tritici | 59.81 | 2e-179 | 527 |
| LLPS-Lem-0886 | Leptosphaeria maculans | 59.39 | 0.0 | 540 |
| LLPS-Asf-1325 | Aspergillus flavus | 58.98 | 7e-150 | 445 |
| LLPS-Pytr-1555 | Pyrenophora triticirepentis | 58.95 | 0.0 | 536 |
| LLPS-Yal-1050 | Yarrowia lipolytica | 58.85 | 0.0 | 551 |
| LLPS-Pyt-0643 | Pyrenophora teres | 58.73 | 0.0 | 536 |
| LLPS-Ved-1182 | Verticillium dahliae | 58.02 | 3e-167 | 492 |
| LLPS-Miv-0334 | Microbotryum violaceum | 58.0 | 0.0 | 527 |
| LLPS-Sac-0357 | Saccharomyces cerevisiae | 57.65 | 5e-179 | 520 |
| LLPS-Asfu-0420 | Aspergillus fumigatus | 57.57 | 0.0 | 546 |
| LLPS-Nef-1501 | Neosartorya fischeri | 57.36 | 0.0 | 542 |
| LLPS-Crn-1026 | Cryptococcus neoformans | 56.81 | 0.0 | 534 |
| LLPS-Trr-0538 | Trichoderma reesei | 56.6 | 3e-175 | 512 |
| LLPS-Abg-0240 | Absidia glauca | 54.61 | 2e-154 | 458 |
| LLPS-Map-0403 | Magnaporthe poae | 50.83 | 6e-134 | 404 |
| LLPS-Mel-0057 | Melampsora laricipopulina | 48.11 | 4e-157 | 466 |
| LLPS-Chr-0656 | Chlamydomonas reinhardtii | 38.73 | 9e-79 | 260 |
| LLPS-Osl-1364 | Ostreococcus lucimarinus | 38.69 | 2e-74 | 246 |
| LLPS-Thc-0104 | Theobroma cacao | 32.65 | 7e-45 | 171 |
| LLPS-Pot-2751 | Populus trichocarpa | 32.47 | 4e-45 | 169 |
| LLPS-Mua-0030 | Musa acuminata | 32.36 | 1e-47 | 177 |
| LLPS-Gor-2660 | Gossypium raimondii | 32.29 | 2e-46 | 173 |
| LLPS-Lep-0802 | Leersia perrieri | 32.14 | 8e-41 | 157 |
| LLPS-Coc-0800 | Corchorus capsularis | 31.92 | 1e-46 | 174 |
| LLPS-Phv-2272 | Phaseolus vulgaris | 31.66 | 1e-44 | 169 |
| LLPS-Via-0666 | Vigna angularis | 31.66 | 4e-44 | 167 |
| LLPS-Zem-2342 | Zea mays | 31.49 | 3e-41 | 159 |
| LLPS-Sol-2114 | Solanum lycopersicum | 31.43 | 5e-43 | 164 |
| LLPS-Cus-0596 | Cucumis sativus | 31.36 | 8e-44 | 166 |
| LLPS-Sot-0148 | Solanum tuberosum | 31.36 | 1e-43 | 165 |
| LLPS-Mae-0210 | Manihot esculenta | 31.3 | 5e-44 | 166 |
| LLPS-Bro-2270 | Brassica oleracea | 31.28 | 1e-42 | 162 |
| LLPS-Org-2073 | Oryza glaberrima | 31.22 | 1e-41 | 160 |
| LLPS-Orr-0912 | Oryza rufipogon | 31.22 | 7e-42 | 160 |
| LLPS-Orm-0247 | Oryza meridionalis | 31.22 | 6e-42 | 160 |
| LLPS-Ors-1894 | Oryza sativa | 31.22 | 7e-42 | 160 |
| LLPS-Orgl-2140 | Oryza glumaepatula | 31.22 | 1e-41 | 160 |
| LLPS-Orni-0531 | Oryza nivara | 31.22 | 1e-41 | 160 |
| LLPS-Glm-2316 | Glycine max | 31.22 | 2e-42 | 162 |
| LLPS-Orb-0791 | Oryza barthii | 31.22 | 1e-41 | 160 |
| LLPS-Ori-2051 | Oryza indica | 31.22 | 1e-41 | 160 |
| LLPS-Brn-3316 | Brassica napus | 31.17 | 4e-43 | 164 |
| LLPS-Arl-0848 | Arabidopsis lyrata | 31.11 | 1e-43 | 165 |
| LLPS-Orp-0711 | Oryza punctata | 31.1 | 3e-43 | 165 |
| LLPS-Prp-2089 | Prunus persica | 31.05 | 1e-44 | 168 |
| LLPS-Nia-2568 | Nicotiana attenuata | 31.03 | 1e-43 | 166 |
| LLPS-Dac-1762 | Daucus carota | 30.95 | 4e-45 | 169 |
| LLPS-Brr-1547 | Brassica rapa | 30.91 | 7e-42 | 160 |
| LLPS-Met-0963 | Medicago truncatula | 30.91 | 7e-43 | 164 |
| LLPS-Brd-1519 | Brachypodium distachyon | 30.91 | 4e-38 | 150 |
| LLPS-Art-1460 | Arabidopsis thaliana | 30.85 | 1e-42 | 163 |
| LLPS-Orbr-1989 | Oryza brachyantha | 30.75 | 6e-44 | 166 |
| LLPS-Tra-1657 | Triticum aestivum | 30.65 | 1e-38 | 151 |
| LLPS-Hea-2653 | Helianthus annuus | 30.65 | 5e-43 | 164 |
| LLPS-Cym-0851 | Cyanidioschyzon merolae | 30.47 | 2e-33 | 135 |
| LLPS-Sob-2181 | Sorghum bicolor | 30.46 | 1e-40 | 157 |
| LLPS-Sei-1916 | Setaria italica | 30.46 | 4e-40 | 155 |
| LLPS-Vir-2102 | Vigna radiata | 30.37 | 7e-42 | 160 |
| LLPS-Tru-0829 | Triticum urartu | 30.32 | 1e-34 | 137 |
| LLPS-Tag-1546 | Taeniopygia guttata | 30.26 | 1e-36 | 146 |
| LLPS-Viv-2423 | Vitis vinifera | 30.16 | 3e-43 | 165 |
| LLPS-Amt-1740 | Amborella trichopoda | 30.05 | 2e-42 | 161 |
| LLPS-Mea-3847 | Mesocricetus auratus | 30.03 | 1e-33 | 137 |
| LLPS-Fia-3776 | Ficedula albicollis | 30.0 | 3e-36 | 145 |
| LLPS-Gaga-3365 | Gallus gallus | 29.87 | 6e-36 | 144 |
| LLPS-Gas-0642 | Galdieria sulphuraria | 29.87 | 4e-41 | 159 |
| LLPS-Ten-2077 | Tetraodon nigroviridis | 29.81 | 9e-35 | 141 |
| LLPS-Tar-1730 | Takifugu rubripes | 29.79 | 2e-37 | 149 |
| LLPS-Scf-2311 | Scleropages formosus | 29.71 | 9e-37 | 147 |
| LLPS-Xet-3527 | Xenopus tropicalis | 29.69 | 8e-37 | 147 |
| LLPS-Cii-1817 | Ciona intestinalis | 29.55 | 1e-34 | 140 |
| LLPS-Xim-0457 | Xiphophorus maculatus | 29.53 | 3e-34 | 139 |
| LLPS-Orn-2698 | Oreochromis niloticus | 29.44 | 2e-35 | 143 |
| LLPS-Cap-3674 | Cavia porcellus | 29.33 | 2e-34 | 140 |
| LLPS-Urm-1361 | Ursus maritimus | 29.33 | 1e-34 | 140 |
| LLPS-Myl-2222 | Myotis lucifugus | 29.33 | 2e-33 | 137 |
| LLPS-Mum-4817 | Mus musculus | 29.31 | 1e-35 | 144 |
| LLPS-Cis-0760 | Ciona savignyi | 29.29 | 5e-33 | 136 |
| LLPS-Cas-3139 | Carlito syrichta | 29.27 | 3e-32 | 134 |
| LLPS-Pes-0462 | Pelodiscus sinensis | 29.18 | 4e-34 | 139 |
| LLPS-Rhb-1972 | Rhinopithecus bieti | 29.07 | 3e-32 | 134 |
| LLPS-Php-1757 | Physcomitrella patens | 29.06 | 4e-34 | 138 |
| LLPS-Ova-0510 | Ovis aries | 29.05 | 1e-33 | 138 |
| LLPS-Meg-1923 | Meleagris gallopavo | 29.04 | 1e-33 | 137 |
| LLPS-Pof-1696 | Poecilia formosa | 28.97 | 1e-33 | 137 |
| LLPS-Tut-1676 | Tursiops truncatus | 28.77 | 2e-32 | 134 |
| LLPS-Otg-4723 | Otolemur garnettii | 28.72 | 4e-32 | 133 |
| LLPS-Lac-4029 | Latimeria chalumnae | 28.72 | 1e-33 | 138 |
| LLPS-Orl-3843 | Oryzias latipes | 28.68 | 7e-32 | 132 |
| LLPS-Anp-1235 | Anas platyrhynchos | 28.53 | 7e-34 | 138 |
| LLPS-Ran-0404 | Rattus norvegicus | 28.53 | 2e-34 | 140 |
| LLPS-Gaa-2699 | Gasterosteus aculeatus | 28.5 | 6e-32 | 133 |
| LLPS-Chc-0736 | Chondrus crispus | 28.39 | 2e-38 | 151 |
| LLPS-Scm-0679 | Scophthalmus maximus | 28.38 | 2e-31 | 131 |
| LLPS-Fud-0793 | Fukomys damarensis | 28.19 | 7e-31 | 129 |
| LLPS-Sem-1715 | Selaginella moellendorffii | 28.17 | 1e-38 | 150 |
| LLPS-Leo-1726 | Lepisosteus oculatus | 27.44 | 8e-31 | 129 |
| LLPS-Asm-3163 | Astyanax mexicanus | 27.25 | 2e-30 | 128 |
| LLPS-Dar-2790 | Danio rerio | 27.2 | 4e-33 | 136 |
| LLPS-Icp-3341 | Ictalurus punctatus | 27.18 | 2e-30 | 128 |
| LLPS-Sah-2641 | Sarcophilus harrisii | 26.32 | 1e-18 | 92.8 |