• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Sah-2053
METTL22

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Methyltransferase like 22
Gene Name: METTL22
Ensembl Gene: ENSSHAG00000000726.1
Ensembl Protein: ENSSHAP00000000813.1
Organism: Sarcophilus harrisii
Taxa ID: 9305
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MVDPEEEETM  EEITFKSDTV  LSDVHLNTPN  KRHLMVRLNA  VGQPVFLSQF  KLLWKKDPWK  60
61    DTQVEDKKQK  NIQIENNTLD  YRSIQKSCGK  NSNGIDCLDK  NETQIHPCMR  IEALLDNDGD  120
121   LEVVRRPRTF  SETKQKEMSR  NKIHPKILTQ  GAENVSEEVQ  ENVRHSMVKI  EHTMATPLED  180
181   VGKQVWRGAF  LLADYILFQC  DLFKSCTVLE  LGAGTGIASI  ITATVAKTVY  CTDVGEDLLA  240
241   MCERNVALNR  NLTATAETGG  VIKVKELNWL  KDDLCTGIDP  QVPFSWSEEE  ISDLYAHTTI  300
301   IMAADVFYDD  DLTDALFKTL  YRITHNLKNA  CTIYLSIEKR  LNFTLRHLDI  TCEAYNHFRF  360
361   SLNDLEKLRD  GKMKFMVEPI  EATFPQFLVY  ERIEQLELWK  IVAAPIS  407
Nucleotide CDS Sequence (FASTA)
1     ATGGAAGAAA  TTACATTTAA  AAGTGATACT  GTGCTGTCTG  ATGTACATCT  AAACACCCCA  60
61    AACAAAAGGC  ACCTCATGGT  GCGCCTGAAT  GCTGTTGGCC  AACCTGTTTT  TCTGTCACAA  120
121   TTCAAACTTC  TGTGGAAGAA  AGATCCTTGG  AAAGATACTC  AAGTTGAAGA  TAAAAAACAA  180
181   AAAAACATTC  AAATAGAAAA  TAATACACTT  GATTACAGAA  ATTGTCTGGA  CAAAAATGAA  240
241   ACTCAAATTC  ACCCTTGTAT  GAGAATAGAA  GCTCTATTGG  ATAATGATGG  TGACTTAGAA  300
301   GTGGTAAGAA  GACCACGGAC  TTTCTCTGAG  ACAAAACAAA  AAGAAATGTC  AAGAAATAAG  360
361   GTATGGCGAG  GAGCTTTCCT  TCTAGCTGAC  TACATCCTGT  TCCAATGTGA  CCTATTCAAA  420
421   AGTTGCACTG  TGCTTGAGCT  TGGGGCAGGA  ACTGGGATTG  CCAGCATCAT  CACAGCAACG  480
481   GTTGCTAAGA  CTGTTTACTG  CACAGATGTG  GGTGAAGATC  TCCTGGCTAT  GTGTGAACGG  540
541   AATGTTGCCC  TAAACAGGAA  CCTAACTGCA  ACAGCAGAAA  CAGGAGGTGT  AATTAAAGTT  600
601   AAAGAACTGA  ATTGGCTAAA  AGATGATTTG  TGCACTGGCA  TAGATCCTCA  AGTTCCATTC  660
661   AGTTGGTCTG  AAGAAGAAAT  TTCTGATTTA  TATGCTCACA  CTACTATCAT  AATGGCAGCT  720
721   GATGTTTTTT  ATGATGATGA  TCTCACAGAT  GCTTTATTTA  AAACACTCTA  CAGAATTACT  780
781   CACAATTTGA  AAAATGCTTG  TACAATCTAC  TTATCAATAG  AGAAAAGACT  AAACTTCACA  840
841   CTTAGACATT  TGGACATTAC  ATGTGAAGCT  TACAATCATT  TTCGATTTTC  CCTAAATGAT  900
901   CTAGAGAAAC  TCAGAGATGG  CAAAATGAAG  TTTATGGTAG  AGCCAATTGA  AGCTACTTTC  960
961   CCCCAGTTCC  TTGTTTATGA  ACGTATAGAG  CAGTTGGAAC  TCTGGAAGAT  TGTTGCTGCA  1020
1021  CCAACATTGA  ATCCTGCCTT  TATCCAATTA  AGAAAATTCT  CTTACTCTTT  TATG  1074

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mod-3666Monodelphis domestica85.050.0 682
LLPS-Ora-2723Ornithorhynchus anatinus73.230.0 571
LLPS-Anp-0133Anas platyrhynchos64.484e-175 502
LLPS-Aon-4390Aotus nancymaae64.160.0 527
LLPS-Meg-0046Meleagris gallopavo64.148e-177 506
LLPS-Pes-3153Pelodiscus sinensis64.130.0 530
LLPS-Loa-3524Loxodonta africana64.00.0 518
LLPS-Paa-4187Papio anubis63.664e-172 498
LLPS-Poa-1127Pongo abelii63.570.0 522
LLPS-Rhb-0171Rhinopithecus bieti63.380.0 520
LLPS-Mum-3575Mus musculus63.380.0 522
LLPS-Ict-2289Ictidomys tridecemlineatus63.169e-178 509
LLPS-Caf-3680Canis familiaris63.132e-178 510
LLPS-Mam-4156Macaca mulatta62.810.0 518
LLPS-Maf-4730Macaca fascicularis62.810.0 518
LLPS-Gog-2291Gorilla gorilla62.810.0 520
LLPS-Tag-0238Taeniopygia guttata62.799e-164 473
LLPS-Aim-4327Ailuropoda melanoleuca62.782e-176 505
LLPS-Fia-2652Ficedula albicollis62.721e-169 488
LLPS-Gaga-2533Gallus gallus62.631e-169 488
LLPS-Ran-0482Rattus norvegicus62.630.0 520
LLPS-Chs-2636Chlorocebus sabaeus62.564e-179 512
LLPS-Urm-1520Ursus maritimus62.533e-176 504
LLPS-Myl-2880Myotis lucifugus62.443e-176 504
LLPS-Cas-0518Carlito syrichta62.411e-175 504
LLPS-Hos-1154Homo sapiens62.310.0 518
LLPS-Pat-2183Pan troglodytes62.310.0 518
LLPS-Otg-0863Otolemur garnettii62.289e-178 509
LLPS-Nol-3788Nomascus leucogenys62.060.0 519
LLPS-Mup-3403Mustela putorius furo62.01e-176 505
LLPS-Eqc-0971Equus caballus61.921e-168 485
LLPS-Cea-4666Cercocebus atys61.874e-171 492
LLPS-Mea-1166Mesocricetus auratus61.422e-173 497
LLPS-Cap-2746Cavia porcellus61.352e-173 498
LLPS-Pap-4671Pan paniscus61.179e-167 479
LLPS-Dio-4354Dipodomys ordii60.417e-169 486
LLPS-Man-4754Macaca nemestrina59.97e-175 502
LLPS-Caj-1250Callithrix jacchus59.314e-176 506
LLPS-Orc-4269Oryctolagus cuniculus58.718e-169 486
LLPS-Fud-2515Fukomys damarensis58.694e-158 458
LLPS-Fec-4536Felis catus57.976e-154 446
LLPS-Sus-0445Sus scrofa57.512e-168 486
LLPS-Ova-1013Ovis aries57.321e-156 454
LLPS-Anc-3446Anolis carolinensis56.894e-155 451
LLPS-Lac-2109Latimeria chalumnae56.63e-140 413
LLPS-Bot-4780Bos taurus55.581e-142 422
LLPS-Mal-2939Mandrillus leucophaeus54.641e-143 420
LLPS-Xet-3055Xenopus tropicalis52.767e-138 407
LLPS-Leo-1334Lepisosteus oculatus52.543e-135 400
LLPS-Icp-0211Ictalurus punctatus52.282e-134 398
LLPS-Scf-3444Scleropages formosus51.262e-128 383
LLPS-Asm-1589Astyanax mexicanus51.137e-127 379
LLPS-Gaa-1236Gasterosteus aculeatus50.257e-131 389
LLPS-Dar-3160Danio rerio50.06e-127 378
LLPS-Pof-1346Poecilia formosa49.881e-130 388
LLPS-Xim-2368Xiphophorus maculatus49.885e-129 384
LLPS-Scm-2346Scophthalmus maximus49.763e-130 388
LLPS-Orl-0157Oryzias latipes49.346e-98 304
LLPS-Orn-3707Oreochromis niloticus46.374e-119 358
LLPS-Ten-2909Tetraodon nigroviridis45.848e-108 329
LLPS-Tar-1895Takifugu rubripes44.539e-100 308
LLPS-Gor-2156Gossypium raimondii38.88e-40 150
LLPS-Sem-2293Selaginella moellendorffii38.612e-2092.8
LLPS-Brn-0253Brassica napus37.833e-32 130
LLPS-Thc-1126Theobroma cacao36.995e-36 140
LLPS-Amt-2349Amborella trichopoda36.824e-39 148
LLPS-Nia-0549Nicotiana attenuata36.766e-36 140
LLPS-Sot-0386Solanum tuberosum36.585e-36 140
LLPS-Mua-2587Musa acuminata35.974e-37 144
LLPS-Glm-1041Glycine max35.942e-38 146
LLPS-Sol-0144Solanum lycopersicum35.949e-35 137
LLPS-Lep-1572Leersia perrieri35.833e-36 140
LLPS-Sei-1304Setaria italica35.695e-38 146
LLPS-Cus-0409Cucumis sativus35.46e-1577.4
LLPS-Pot-2459Populus trichocarpa35.321e-35 139
LLPS-Php-1573Physcomitrella patens35.111e-36 143
LLPS-Tra-0247Triticum aestivum35.042e-34 135
LLPS-Orp-1463Oryza punctata35.023e-35 138
LLPS-Ors-1279Oryza sativa34.91e-35 139
LLPS-Orr-1840Oryza rufipogon34.889e-36 139
LLPS-Org-0256Oryza glaberrima34.886e-36 140
LLPS-Orb-0894Oryza barthii34.886e-36 140
LLPS-Orni-2017Oryza nivara34.889e-36 139
LLPS-Orgl-0296Oryza glumaepatula34.881e-35 139
LLPS-Mae-1850Manihot esculenta34.681e-33 133
LLPS-Met-1519Medicago truncatula34.684e-37 143
LLPS-Sob-0267Sorghum bicolor34.654e-37 143
LLPS-Orm-1388Oryza meridionalis34.657e-35 137
LLPS-Hov-1362Hordeum vulgare34.653e-35 139
LLPS-Art-2555Arabidopsis thaliana34.558e-34 133
LLPS-Dac-0989Daucus carota34.549e-35 136
LLPS-Ori-1180Oryza indica34.512e-35 140
LLPS-Vir-0604Vigna radiata34.133e-29 118
LLPS-Bro-0797Brassica oleracea33.991e-31 132
LLPS-Zem-2175Zea mays33.857e-35 137
LLPS-Hea-2009Helianthus annuus33.761e-38 147
LLPS-Orbr-0774Oryza brachyantha33.596e-29 120
LLPS-Viv-1081Vitis vinifera33.552e-37 144
LLPS-Drm-0282Drosophila melanogaster33.333e-25 108
LLPS-Tru-1389Triticum urartu33.072e-30 124
LLPS-Cii-1904Ciona intestinalis32.848e-1062.8
LLPS-Brd-2131Brachypodium distachyon31.831e-36 142
LLPS-Coc-2365Corchorus capsularis31.537e-37 142
LLPS-Prp-2509Prunus persica30.878e-29 119
LLPS-Phv-0111Phaseolus vulgaris29.418e-35 137
LLPS-Via-1229Vigna angularis28.532e-27 115