LLPS-Sac-1701
NAB6
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | RNA-binding protein NAB6; Nucleic acid-binding protein 6 |
| Gene Name: | NAB6, YML117W, YM8339.02 |
| Ensembl Gene: | YML117W |
| Ensembl Protein: | YML117W_mRNA |
| Organism: | Saccharomyces cerevisiae |
| Taxa ID: | 559292 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| Stress granule | "...To the list of proteins identified and validated in stress granules, we added proteins known to be in stress granules but not enriched in our mass spectrometric analysis to create an initial list of yeast stress granule proteins." | Saccharomyces cerevisiae | 26777405 |
▼ FUNCTION
| RNA-binding protein that associates with mRNAs encoding cell wall proteins. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | YML117W_mRNA | YML117W_mRNA |
| UniProt | Q03735, NAB6_YEAST, D6W0G7 | |
| GeneBank | BK006946, Z49210 | DAA09781.1, CAA89101.1 |
| RefSeq | NM_001182479.1 | NP_013589.1 |
| Entrez | 854922 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSNSNSKKPV ANYAYRQQQD YNGMNAMVGN PMMYHPVDFV NGAGQYGPSQ HPAYYTNSPL 60 61 PNIPPTPFDT AYGASLFPSH LLMGSPFVSS PNMQSGYNSA RSSNLKRKAY SRPVSNHNGY 120 121 NGNSNSNQNN TNNGMVTPSN YYRMGRNSFS RNNNSTRNVT HNNNKGCDTR NNSGRRTFAR 180 181 NNIFDDILPE MLLQRPFCIN YKVLPTGDDA YRTRSLLIEN VDHSIDLHSI VKNFVKSNTL 240 241 ESAYLIEGGK SDDSKDVETK NLSILISFLT KGDCLNFYNN ILQRLSEFKT FLKSEALNLK 300 301 FVCLNYDPKC LPTFIESEAL TENAEEADIT NGSTMISASL HHNIANKDAT RSIIIEFKSP 360 361 VEKSDLFKKK LQFLDRSKNK RYILESIDLV NTDVPSNQFP ENYAVLTFLN ISMAIEVLDY 420 421 LKKYSKNLGI SKCFYVSLAP LVVSSARSSV ANIYEGKTST HRLSVPSVTA GNNNDSNNNG 480 481 NNNKSNMSGI TTLNNNSSIG VSVYGHSNMS LTSLSSSVSL NEEIDMLATK LQGVELDGTY 540 541 LEINYRDYQT PTIEEHSTHL SNVKISKTTE NSRQFSQDIP SPLPLNEHMF MNDSNQSNGA 600 601 IIPQQLIATP SPVSPNLQMN QRVLPNPITQ SLEQNFNVSA KVASSMGSDI GNRTIYIGNI 660 661 NPRSKAEDIC NVVRGGILQS IKYIPEKKIC FVTFIEAPSA VQFYANSFID PIVLHGNMLR 720 721 VGWGHYSGPL PKLISLAVTI GASRNVYVSL PEFAFKEKFI HDPQYKKLHE TLSLPDAEQL 780 781 REDFSTYGDI EQINYLSDSH CCWINFMNIS SAISLVEEMN KESTVQNESG EVTLKRATEE 840 841 KFGGRYKGLL INYGKDRCGN INKNLIAGKN SRFYKKVKRP SYNIRLSKLE EKRRQNEIDE 900 901 KEKAFDKPLN LESLGISLDA HKDNGGGETG TANNTGHENE SELEAENENG NETGSFGGLG 960 961 LAVASSDVKR ATSDETDYED IFNKSSGSSD SSSDVEVIMH SPSDPEYALK SQTLRSSSQT 1020 1021 VINSKRPVKI EDEEEAVGMS QLNYRSSLRQ APPRAPSTLS YNHSKNNETP MQDIFTNGET 1080 1081 ANNRKKKRGS FARHRTIPGS DVMAQYLAQV QHSTFMYAAN ILGASAEDNT HPDE 1134 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCAAATT CCAATTCAAA AAAACCTGTT GCGAATTACG CATACCGTCA ACAGCAAGAT 60 61 TATAATGGGA TGAACGCCAT GGTGGGAAAT CCAATGATGT ATCATCCTGT TGATTTCGTA 120 121 AACGGTGCCG GCCAATATGG TCCTTCTCAA CACCCAGCAT ATTACACCAA CTCACCATTA 180 181 CCTAATATTC CACCAACACC TTTTGATACT GCATACGGTG CCAGTCTTTT TCCATCTCAC 240 241 CTATTGATGG GATCTCCATT TGTTTCCTCG CCTAACATGC AAAGTGGCTA TAATTCTGCA 300 301 AGATCATCTA ATCTCAAAAG AAAGGCTTAT TCGAGGCCCG TTTCTAATCA TAACGGTTAC 360 361 AACGGAAACA GTAACAGTAA CCAAAACAAT ACTAATAACG GAATGGTAAC ACCCTCGAAC 420 421 TATTATAGAA TGGGGAGAAA TTCTTTCTCG AGGAACAACA ACAGTACGAG GAATGTTACT 480 481 CACAACAACA ATAAGGGGTG CGACACCCGG AACAACAGTG GAAGAAGAAC ATTCGCAAGG 540 541 AATAACATTT TCGACGACAT ACTTCCAGAA ATGCTTTTAC AAAGACCCTT TTGTATTAAT 600 601 TACAAGGTTC TACCGACTGG TGATGATGCT TATAGAACTA GGTCGCTGCT TATTGAAAAT 660 661 GTGGATCATT CTATTGATTT ACACTCTATA GTCAAAAATT TTGTCAAATC CAATACTCTG 720 721 GAAAGTGCCT ACTTAATTGA AGGAGGGAAG AGCGATGATT CAAAAGATGT AGAGACTAAA 780 781 AATCTATCCA TTCTAATAAG CTTTCTAACC AAAGGCGACT GTTTGAACTT TTACAATAAC 840 841 ATTTTACAAA GGTTATCTGA ATTCAAAACA TTTTTGAAAT CTGAAGCACT AAATCTGAAA 900 901 TTTGTTTGTC TAAACTATGA TCCCAAATGC CTCCCTACCT TTATTGAGAG TGAAGCGTTA 960 961 ACAGAAAACG CTGAAGAAGC CGACATTACC AATGGTTCAA CAATGATCAG TGCTTCGCTG 1020 1021 CATCATAATA TAGCGAACAA AGATGCTACA AGGTCGATTA TAATTGAATT CAAAAGCCCC 1080 1081 GTGGAGAAAA GCGATTTATT CAAAAAGAAA TTACAATTTT TGGACAGGTC AAAAAACAAA 1140 1141 AGATACATTT TGGAATCTAT CGATTTAGTG AACACAGATG TACCTTCCAA TCAATTTCCT 1200 1201 GAAAATTACG CCGTTTTAAC CTTTTTGAAT ATCTCTATGG CTATTGAAGT TCTCGATTAT 1260 1261 TTGAAAAAAT ACTCCAAAAA CTTAGGCATT TCTAAATGTT TTTACGTATC CCTAGCCCCG 1320 1321 TTGGTAGTTA GCTCAGCCAG ATCTTCGGTT GCTAATATTT ACGAGGGTAA AACGAGCACA 1380 1381 CATCGTTTAT CGGTGCCTTC TGTTACTGCT GGGAACAATA ACGATAGCAA CAACAACGGA 1440 1441 AACAATAATA AAAGTAATAT GAGTGGTATC ACCACACTCA ATAATAATAG TAGTATTGGT 1500 1501 GTTTCCGTAT ACGGTCACTC TAATATGAGT TTAACCAGTC TGTCATCATC TGTATCTTTA 1560 1561 AATGAAGAGA TTGATATGCT TGCGACGAAA CTTCAAGGGG TAGAACTTGA TGGGACTTAT 1620 1621 TTAGAAATCA ACTATCGCGA CTATCAAACA CCAACTATTG AAGAACACTC TACTCACTTG 1680 1681 AGCAATGTCA AAATTTCAAA GACAACAGAA AACTCTAGGC AATTTTCTCA AGATATCCCA 1740 1741 TCACCTTTGC CATTAAATGA ACATATGTTT ATGAATGATT CTAATCAGTC CAATGGAGCG 1800 1801 ATAATACCTC AACAGTTAAT AGCCACACCT TCTCCGGTAT CCCCCAATTT GCAAATGAAT 1860 1861 CAAAGGGTGT TGCCGAATCC AATAACTCAA AGTTTGGAGC AAAATTTCAA CGTTTCGGCC 1920 1921 AAAGTGGCAT CATCCATGGG TTCAGACATA GGCAATAGAA CAATTTATAT AGGAAACATT 1980 1981 AATCCAAGAT CAAAGGCGGA GGATATCTGT AATGTCGTGC GTGGAGGAAT CCTTCAGAGC 2040 2041 ATTAAGTACA TACCGGAGAA GAAGATATGC TTTGTTACTT TCATCGAAGC TCCATCCGCT 2100 2101 GTACAGTTCT ATGCAAATTC ATTTATTGAT CCAATAGTGT TACATGGGAA TATGTTGAGA 2160 2161 GTTGGATGGG GGCATTATTC TGGTCCATTA CCGAAATTAA TCTCGTTGGC TGTTACGATC 2220 2221 GGGGCAAGTA GGAATGTCTA CGTAAGCCTA CCAGAGTTTG CATTTAAGGA AAAGTTTATT 2280 2281 CACGACCCTC AGTACAAAAA ATTGCATGAA ACACTATCTT TACCAGATGC GGAACAACTA 2340 2341 AGAGAGGACT TTAGTACCTA TGGTGATATT GAGCAGATTA ACTATTTGAG TGATAGCCAT 2400 2401 TGCTGTTGGA TAAATTTCAT GAATATATCT TCTGCGATTA GTCTTGTTGA AGAAATGAAT 2460 2461 AAGGAATCCA CAGTACAAAA TGAATCCGGT GAAGTGACGC TTAAAAGGGC GACTGAGGAA 2520 2521 AAATTCGGTG GCCGTTATAA GGGCCTTCTG ATAAACTACG GCAAAGATCG TTGTGGCAAT 2580 2581 ATAAACAAAA ATTTGATAGC AGGTAAAAAT TCAAGATTCT ATAAGAAAGT TAAAAGACCG 2640 2641 AGCTATAATA TACGTTTGAG TAAGTTGGAA GAAAAGAGGA GGCAGAATGA AATCGATGAA 2700 2701 AAGGAAAAGG CTTTTGATAA ACCCTTGAAC TTGGAATCCC TAGGAATTAG TCTGGACGCA 2760 2761 CATAAGGACA ACGGCGGTGG TGAAACAGGA ACTGCAAATA ATACTGGGCA TGAAAATGAA 2820 2821 AGTGAACTAG AGGCTGAAAA TGAAAACGGT AATGAGACTG GAAGTTTCGG TGGACTGGGT 2880 2881 CTCGCTGTGG CGAGCTCTGA CGTCAAACGT GCGACATCGG ATGAAACTGA TTATGAAGAT 2940 2941 ATATTTAACA AGTCATCGGG ATCTTCCGAC TCGTCATCAG ACGTCGAGGT CATTATGCAC 3000 3001 TCCCCGAGCG ATCCTGAATA CGCTTTAAAA TCACAAACTC TAAGAAGCTC GAGTCAGACC 3060 3061 GTCATTAATA GTAAGAGACC AGTAAAGATA GAAGACGAGG AAGAAGCCGT AGGAATGTCA 3120 3121 CAGCTCAATT ATAGGTCGTC ATTAAGACAA GCTCCTCCAA GAGCTCCCTC AACTTTGTCA 3180 3181 TATAATCACT CGAAGAACAA CGAAACGCCA ATGCAAGATA TTTTCACAAA TGGCGAAACA 3240 3241 GCAAATAACA GAAAGAAGAA GAGAGGATCT TTTGCAAGGC ATAGAACGAT ACCAGGATCT 3300 3301 GACGTCATGG CCCAATACCT TGCACAAGTG CAACATTCGA CATTTATGTA TGCAGCCAAT 3360 3361 ATTTTGGGCG CCTCTGCGGA AGACAACACG CATCCTGACG AGTAG 3405 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Cellular Component | Cytoplasmic stress granule | |
Molecular Function | MRNA binding |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Asg-0620 | Ashbya gossypii | 68.75 | 4e-06 | 55.5 |
| LLPS-Aso-0351 | Aspergillus oryzae | 46.23 | 5e-48 | 189 |
| LLPS-Asf-0647 | Aspergillus flavus | 46.23 | 2e-48 | 190 |
| LLPS-Asfu-1193 | Aspergillus fumigatus | 46.23 | 2e-48 | 190 |
| LLPS-Nef-1635 | Neosartorya fischeri | 46.23 | 3e-48 | 190 |
| LLPS-Asc-0604 | Aspergillus clavatus | 45.28 | 2e-47 | 187 |
| LLPS-Tum-0585 | Tuber melanosporum | 44.34 | 3e-46 | 182 |
| LLPS-Asn-1393 | Aspergillus nidulans | 44.34 | 2e-47 | 187 |
| LLPS-Lem-1321 | Leptosphaeria maculans | 43.4 | 2e-45 | 181 |
| LLPS-Trv-0603 | Trichoderma virens | 43.4 | 6e-46 | 182 |
| LLPS-Zyt-0209 | Zymoseptoria tritici | 43.19 | 3e-46 | 183 |
| LLPS-Asni-1541 | Aspergillus niger | 43.04 | 2e-48 | 190 |
| LLPS-Pyt-1404 | Pyrenophora teres | 42.92 | 3e-45 | 181 |
| LLPS-Mao-1057 | Magnaporthe oryzae | 42.92 | 2e-45 | 181 |
| LLPS-Pytr-1031 | Pyrenophora triticirepentis | 42.92 | 4e-45 | 180 |
| LLPS-Beb-0259 | Beauveria bassiana | 42.92 | 2e-45 | 181 |
| LLPS-Gag-1217 | Gaeumannomyces graminis | 42.86 | 6e-46 | 182 |
| LLPS-Map-0495 | Magnaporthe poae | 42.86 | 6e-46 | 182 |
| LLPS-Cog-0128 | Colletotrichum gloeosporioides | 42.86 | 4e-46 | 182 |
| LLPS-Ved-1399 | Verticillium dahliae | 42.72 | 2e-45 | 181 |
| LLPS-Ast-0488 | Aspergillus terreus | 42.67 | 1e-48 | 191 |
| LLPS-Phn-1037 | Phaeosphaeria nodorum | 42.45 | 5e-45 | 180 |
| LLPS-Blg-0951 | Blumeria graminis | 42.41 | 3e-46 | 183 |
| LLPS-Cogr-0739 | Colletotrichum graminicola | 42.4 | 7e-46 | 182 |
| LLPS-Trr-1586 | Trichoderma reesei | 42.4 | 4e-46 | 182 |
| LLPS-Nec-1068 | Neurospora crassa | 41.96 | 2e-46 | 183 |
| LLPS-Fus-1311 | Fusarium solani | 41.96 | 3e-46 | 183 |
| LLPS-Coo-0906 | Colletotrichum orbiculare | 41.94 | 2e-45 | 180 |
| LLPS-Dos-1603 | Dothistroma septosporum | 41.55 | 6e-45 | 179 |
| LLPS-Yal-1411 | Yarrowia lipolytica | 41.35 | 1e-45 | 181 |
| LLPS-Fuv-1547 | Fusarium verticillioides | 41.07 | 4e-45 | 180 |
| LLPS-Fuo-0595 | Fusarium oxysporum | 41.07 | 3e-45 | 180 |
| LLPS-Put-0479 | Puccinia triticina | 40.19 | 1e-39 | 161 |
| LLPS-Pug-0630 | Puccinia graminis | 40.19 | 9e-40 | 160 |
| LLPS-Miv-1595 | Microbotryum violaceum | 40.18 | 4e-44 | 176 |
| LLPS-Mel-1267 | Melampsora laricipopulina | 39.07 | 4e-39 | 159 |
| LLPS-Usm-1426 | Ustilago maydis | 38.89 | 6e-41 | 166 |
| LLPS-Scc-1077 | Schizosaccharomyces cryophilus | 38.57 | 2e-38 | 157 |
| LLPS-Abg-1559 | Absidia glauca | 38.29 | 2e-35 | 149 |
| LLPS-Scp-0140 | Schizosaccharomyces pombe | 38.1 | 4e-39 | 158 |
| LLPS-Spr-1568 | Sporisorium reilianum | 38.03 | 3e-40 | 164 |
| LLPS-Crn-0639 | Cryptococcus neoformans | 36.19 | 5e-34 | 143 |
| LLPS-Kop-1202 | Komagataella pastoris | 36.02 | 1e-42 | 169 |