LLPS-Sac-1141
RPL11A
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | 60S ribosomal protein L11-A; L16; Large ribosomal subunit protein uL5-A; RP39; YL22 |
| Gene Name: | RPL11A, RP39A, RPL16A, YPR102C, P8283.14 |
| Ensembl Gene: | YPR102C |
| Ensembl Protein: | YPR102C_mRNA |
| Organism: | Saccharomyces cerevisiae |
| Taxa ID: | 559292 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, P-body, Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | YPR102C_mRNA | YPR102C_mRNA |
| UniProt | P0C0W9, RL11A_YEAST, D6W4A0, P06380 | |
| GeneBank | AY693151, BK006949, U32445, X01029 | AAT93170.1, DAA11516.1, AAB68072.1, CAA25515.1 |
| RefSeq | NM_001184199.1 | NP_015427.1 |
| Entrez | 856217 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSAKAQNPMR DLKIEKLVLN ISVGESGDRL TRASKVLEQL SGQTPVQSKA RYTVRTFGIR 60 61 RNEKIAVHVT VRGPKAEEIL ERGLKVKEYQ LRDRNFSATG NFGFGIDEHI DLGIKYDPSI 120 121 GIFGMDFYVV MNRPGARVTR RKRCKGTVGN SHKTTKEDTV SWFKQKYDAD VLDK 174 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCTGCCA AAGCTCAAAA CCCTATGCGT GATTTGAAGA TCGAAAAGTT GGTCTTAAAC 60 61 ATTTCTGTTG GTGAATCTGG TGACAGATTG ACCAGAGCCT CCAAGGTTTT AGAGCAATTA 120 121 TCTGGTCAAA CTCCAGTTCA ATCCAAGGCC AGATACACTG TCAGAACTTT CGGTATCAGA 180 181 AGAAACGAAA AAATTGCTGT TCACGTTACC GTCAGAGGTC CAAAGGCTGA AGAAATTTTG 240 241 GAAAGAGGTT TGAAGGTCAA GGAATACCAA TTGAGAGACA GAAACTTCTC TGCTACCGGT 300 301 AACTTCGGTT TCGGTATTGA CGAACACATT GACTTGGGTA TCAAGTATGA CCCATCCATC 360 361 GGTATTTTCG GTATGGATTT CTATGTCGTC ATGAACAGAC CAGGTGCTAG AGTCACTAGA 420 421 AGAAAGAGAT GTAAGGGTAC CGTTGGTAAC TCCCACAAGA CAACTAAGGA AGACACCGTC 480 481 TCTTGGTTCA AGCAAAAGTA CGATGCTGAT GTTTTGGACA AATAA 525 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosolic large ribosomal subunit | |
Cellular Component | Nucleus | |
Molecular Function | RRNA binding | |
Molecular Function | Structural constituent of ribosome | |
Biological Process | Cytoplasmic translation | |
Biological Process | Ribosomal large subunit assembly |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Asg-0244 | Ashbya gossypii | 89.66 | 1e-115 | 332 |
| LLPS-Kop-0024 | Komagataella pastoris | 85.06 | 4e-110 | 318 |
| LLPS-Abg-0952 | Absidia glauca | 81.55 | 3e-98 | 288 |
| LLPS-Fuo-0696 | Fusarium oxysporum | 81.18 | 4e-99 | 290 |
| LLPS-Fuv-0678 | Fusarium verticillioides | 81.18 | 4e-99 | 290 |
| LLPS-Scp-1021 | Schizosaccharomyces pombe | 81.03 | 3e-101 | 296 |
| LLPS-Mel-0032 | Melampsora laricipopulina | 80.98 | 3e-94 | 279 |
| LLPS-Trr-0618 | Trichoderma reesei | 80.59 | 3e-98 | 288 |
| LLPS-Mao-0099 | Magnaporthe oryzae | 80.59 | 5e-99 | 290 |
| LLPS-Nec-0481 | Neurospora crassa | 80.36 | 5e-98 | 288 |
| LLPS-Trv-0037 | Trichoderma virens | 80.0 | 1e-97 | 286 |
| LLPS-Beb-0720 | Beauveria bassiana | 80.0 | 6e-98 | 287 |
| LLPS-Scj-0004 | Schizosaccharomyces japonicus | 79.89 | 3e-100 | 293 |
| LLPS-Scc-0414 | Schizosaccharomyces cryophilus | 79.89 | 2e-99 | 291 |
| LLPS-Ved-0417 | Verticillium dahliae | 79.53 | 2e-98 | 289 |
| LLPS-Cogr-0936 | Colletotrichum graminicola | 79.41 | 3e-97 | 286 |
| LLPS-Fus-0598 | Fusarium solani | 79.41 | 8e-97 | 285 |
| LLPS-Gag-0553 | Gaeumannomyces graminis | 78.95 | 8e-98 | 287 |
| LLPS-Coo-1093 | Colletotrichum orbiculare | 78.95 | 3e-97 | 286 |
| LLPS-Asfu-0093 | Aspergillus fumigatus | 78.57 | 6e-97 | 285 |
| LLPS-Map-0422 | Magnaporthe poae | 78.36 | 4e-97 | 285 |
| LLPS-Put-0883 | Puccinia triticina | 78.26 | 5e-90 | 267 |
| LLPS-Phn-0550 | Phaeosphaeria nodorum | 78.11 | 4e-97 | 285 |
| LLPS-Miv-1331 | Microbotryum violaceum | 78.03 | 5e-99 | 290 |
| LLPS-Nef-0015 | Neosartorya fischeri | 77.98 | 4e-96 | 283 |
| LLPS-Asn-0440 | Aspergillus nidulans | 77.98 | 2e-97 | 286 |
| LLPS-Pytr-1409 | Pyrenophora triticirepentis | 77.51 | 1e-96 | 284 |
| LLPS-Pyt-0161 | Pyrenophora teres | 77.51 | 7e-97 | 285 |
| LLPS-Aso-0286 | Aspergillus oryzae | 77.38 | 2e-95 | 281 |
| LLPS-Zyt-0114 | Zymoseptoria tritici | 77.38 | 4e-95 | 280 |
| LLPS-Asf-0002 | Aspergillus flavus | 77.38 | 2e-95 | 281 |
| LLPS-Asc-0921 | Aspergillus clavatus | 77.38 | 7e-95 | 280 |
| LLPS-Asni-0026 | Aspergillus niger | 77.38 | 3e-96 | 283 |
| LLPS-Yal-0275 | Yarrowia lipolytica | 77.33 | 3e-99 | 291 |
| LLPS-Lem-1159 | Leptosphaeria maculans | 77.19 | 2e-97 | 286 |
| LLPS-Dos-0775 | Dothistroma septosporum | 76.79 | 3e-95 | 281 |
| LLPS-Crn-0050 | Cryptococcus neoformans | 76.65 | 1e-92 | 274 |
| LLPS-Pug-0187 | Puccinia graminis | 76.33 | 1e-92 | 274 |
| LLPS-Drm-0589 | Drosophila melanogaster | 76.33 | 1e-91 | 272 |
| LLPS-Ast-0884 | Aspergillus terreus | 76.19 | 6e-94 | 277 |
| LLPS-Cae-0111 | Caenorhabditis elegans | 75.15 | 2e-90 | 269 |
| LLPS-Usm-0553 | Ustilago maydis | 74.85 | 2e-92 | 273 |
| LLPS-Spr-0535 | Sporisorium reilianum | 74.85 | 2e-92 | 273 |
| LLPS-Bro-2991 | Brassica oleracea | 74.27 | 5e-90 | 268 |
| LLPS-Art-0846 | Arabidopsis thaliana | 74.27 | 4e-90 | 268 |
| LLPS-Brr-1722 | Brassica rapa | 74.27 | 5e-90 | 269 |
| LLPS-Arl-0125 | Arabidopsis lyrata | 74.27 | 4e-90 | 268 |
| LLPS-Brn-3090 | Brassica napus | 74.27 | 8e-90 | 269 |
| LLPS-Blg-0301 | Blumeria graminis | 74.12 | 4e-93 | 275 |
| LLPS-Orr-0449 | Oryza rufipogon | 73.68 | 6e-89 | 266 |
| LLPS-Org-1026 | Oryza glaberrima | 73.68 | 3e-89 | 266 |
| LLPS-Ors-1371 | Oryza sativa | 73.68 | 3e-89 | 266 |
| LLPS-Orp-1321 | Oryza punctata | 73.68 | 3e-89 | 266 |
| LLPS-Orbr-0345 | Oryza brachyantha | 73.68 | 1e-89 | 266 |
| LLPS-Amt-0225 | Amborella trichopoda | 73.68 | 3e-89 | 266 |
| LLPS-Orgl-0325 | Oryza glumaepatula | 73.68 | 3e-89 | 266 |
| LLPS-Sot-1126 | Solanum tuberosum | 73.68 | 2e-90 | 269 |
| LLPS-Cus-0519 | Cucumis sativus | 73.68 | 6e-90 | 267 |
| LLPS-Sol-1345 | Solanum lycopersicum | 73.68 | 2e-90 | 269 |
| LLPS-Cii-1733 | Ciona intestinalis | 73.68 | 2e-87 | 261 |
| LLPS-Orb-0266 | Oryza barthii | 73.68 | 3e-89 | 266 |
| LLPS-Dac-0051 | Daucus carota | 73.68 | 7e-89 | 265 |
| LLPS-Orni-0146 | Oryza nivara | 73.68 | 3e-89 | 266 |
| LLPS-Ran-1393 | Rattus norvegicus | 73.42 | 3e-82 | 248 |
| LLPS-Bot-0060 | Bos taurus | 73.29 | 6e-85 | 254 |
| LLPS-Orm-0654 | Oryza meridionalis | 73.1 | 4e-89 | 265 |
| LLPS-Gor-1961 | Gossypium raimondii | 73.1 | 3e-88 | 263 |
| LLPS-Sob-0317 | Sorghum bicolor | 73.1 | 4e-89 | 265 |
| LLPS-Nia-0440 | Nicotiana attenuata | 73.1 | 8e-90 | 267 |
| LLPS-Mae-1297 | Manihot esculenta | 73.1 | 1e-88 | 264 |
| LLPS-Phv-0538 | Phaseolus vulgaris | 73.1 | 6e-89 | 265 |
| LLPS-Lep-1765 | Leersia perrieri | 73.1 | 4e-89 | 265 |
| LLPS-Met-1981 | Medicago truncatula | 73.1 | 1e-88 | 264 |
| LLPS-Glm-0034 | Glycine max | 73.1 | 8e-89 | 265 |
| LLPS-Cis-0071 | Ciona savignyi | 73.1 | 8e-87 | 259 |
| LLPS-Ori-1358 | Oryza indica | 73.1 | 4e-89 | 265 |
| LLPS-Thc-0479 | Theobroma cacao | 73.1 | 3e-88 | 263 |
| LLPS-Xet-1018 | Xenopus tropicalis | 73.05 | 9e-88 | 262 |
| LLPS-Coc-0167 | Corchorus capsularis | 72.89 | 3e-85 | 255 |
| LLPS-Via-1912 | Vigna angularis | 72.89 | 3e-85 | 255 |
| LLPS-Vir-0988 | Vigna radiata | 72.89 | 2e-85 | 256 |
| LLPS-Ten-2074 | Tetraodon nigroviridis | 72.78 | 4e-87 | 260 |
| LLPS-Tar-2045 | Takifugu rubripes | 72.78 | 4e-87 | 260 |
| LLPS-Fia-1584 | Ficedula albicollis | 72.56 | 3e-84 | 253 |
| LLPS-Chs-4166 | Chlorocebus sabaeus | 72.56 | 5e-85 | 254 |
| LLPS-Prp-0760 | Prunus persica | 72.51 | 5e-88 | 263 |
| LLPS-Zem-0890 | Zea mays | 72.51 | 2e-88 | 263 |
| LLPS-Viv-0387 | Vitis vinifera | 72.51 | 5e-88 | 263 |
| LLPS-Pot-0078 | Populus trichocarpa | 72.51 | 3e-87 | 261 |
| LLPS-Sei-0260 | Setaria italica | 72.51 | 2e-88 | 263 |
| LLPS-Php-0672 | Physcomitrella patens | 72.51 | 1e-87 | 261 |
| LLPS-Hea-0255 | Helianthus annuus | 72.51 | 3e-88 | 263 |
| LLPS-Mua-0489 | Musa acuminata | 72.51 | 2e-86 | 260 |
| LLPS-Eqc-2317 | Equus caballus | 72.46 | 2e-87 | 261 |
| LLPS-Cap-1329 | Cavia porcellus | 72.46 | 3e-87 | 261 |
| LLPS-Caf-1863 | Canis familiaris | 72.46 | 2e-87 | 261 |
| LLPS-Poa-0885 | Pongo abelii | 72.46 | 2e-87 | 261 |
| LLPS-Mam-0348 | Macaca mulatta | 72.46 | 2e-87 | 261 |
| LLPS-Cas-0440 | Carlito syrichta | 72.46 | 2e-87 | 261 |
| LLPS-Gaga-0780 | Gallus gallus | 72.46 | 1e-86 | 259 |
| LLPS-Tag-0732 | Taeniopygia guttata | 72.46 | 1e-86 | 259 |
| LLPS-Nol-2244 | Nomascus leucogenys | 72.46 | 2e-87 | 261 |
| LLPS-Anc-0839 | Anolis carolinensis | 72.46 | 1e-87 | 261 |
| LLPS-Mod-0600 | Monodelphis domestica | 72.46 | 8e-87 | 259 |
| LLPS-Fec-0757 | Felis catus | 72.46 | 1e-86 | 260 |
| LLPS-Urm-0984 | Ursus maritimus | 72.46 | 7e-87 | 260 |
| LLPS-Pap-0404 | Pan paniscus | 72.46 | 2e-87 | 261 |
| LLPS-Pat-1629 | Pan troglodytes | 72.46 | 2e-87 | 261 |
| LLPS-Meg-1587 | Meleagris gallopavo | 72.46 | 1e-86 | 259 |
| LLPS-Hos-1283 | Homo sapiens | 72.46 | 2e-87 | 261 |
| LLPS-Man-1902 | Macaca nemestrina | 72.46 | 2e-87 | 261 |
| LLPS-Pes-1698 | Pelodiscus sinensis | 72.46 | 5e-87 | 260 |
| LLPS-Otg-1825 | Otolemur garnettii | 72.46 | 3e-87 | 261 |
| LLPS-Rhb-0552 | Rhinopithecus bieti | 72.46 | 2e-87 | 261 |
| LLPS-Orc-0671 | Oryctolagus cuniculus | 72.46 | 2e-87 | 261 |
| LLPS-Tut-0410 | Tursiops truncatus | 72.46 | 3e-87 | 260 |
| LLPS-Dio-0335 | Dipodomys ordii | 72.46 | 3e-87 | 261 |
| LLPS-Ova-0961 | Ovis aries | 72.46 | 3e-87 | 261 |
| LLPS-Myl-0223 | Myotis lucifugus | 72.46 | 2e-87 | 261 |
| LLPS-Mup-0451 | Mustela putorius furo | 72.46 | 2e-87 | 261 |
| LLPS-Aim-0934 | Ailuropoda melanoleuca | 72.46 | 3e-87 | 261 |
| LLPS-Paa-0230 | Papio anubis | 72.46 | 2e-87 | 261 |
| LLPS-Mal-0520 | Mandrillus leucophaeus | 72.46 | 2e-87 | 261 |
| LLPS-Ora-0932 | Ornithorhynchus anatinus | 72.46 | 8e-87 | 259 |
| LLPS-Mum-1862 | Mus musculus | 72.46 | 2e-87 | 261 |
| LLPS-Maf-0133 | Macaca fascicularis | 72.46 | 2e-87 | 261 |
| LLPS-Cea-2624 | Cercocebus atys | 72.46 | 2e-87 | 261 |
| LLPS-Sah-0196 | Sarcophilus harrisii | 72.46 | 1e-86 | 259 |
| LLPS-Gog-1321 | Gorilla gorilla | 72.46 | 2e-87 | 261 |
| LLPS-Caj-1302 | Callithrix jacchus | 72.46 | 2e-87 | 261 |
| LLPS-Fud-1785 | Fukomys damarensis | 72.46 | 3e-87 | 261 |
| LLPS-Pof-0199 | Poecilia formosa | 72.19 | 5e-87 | 260 |
| LLPS-Xim-0144 | Xiphophorus maculatus | 72.19 | 5e-87 | 260 |
| LLPS-Gaa-0704 | Gasterosteus aculeatus | 72.19 | 7e-87 | 260 |
| LLPS-Dar-0609 | Danio rerio | 71.93 | 1e-87 | 261 |
| LLPS-Brd-1064 | Brachypodium distachyon | 71.93 | 5e-87 | 260 |
| LLPS-Sus-1833 | Sus scrofa | 71.86 | 2e-86 | 258 |
| LLPS-Orn-0057 | Oreochromis niloticus | 71.6 | 1e-86 | 259 |
| LLPS-Scf-1512 | Scleropages formosus | 71.6 | 2e-86 | 258 |
| LLPS-Icp-1051 | Ictalurus punctatus | 71.6 | 1e-86 | 259 |
| LLPS-Asm-0386 | Astyanax mexicanus | 71.6 | 1e-86 | 259 |
| LLPS-Orl-1519 | Oryzias latipes | 71.52 | 5e-84 | 253 |
| LLPS-Sem-0428 | Selaginella moellendorffii | 71.51 | 9e-88 | 262 |
| LLPS-Tra-1293 | Triticum aestivum | 71.35 | 8e-87 | 259 |
| LLPS-Hov-0336 | Hordeum vulgare | 71.35 | 5e-87 | 260 |
| LLPS-Scm-0885 | Scophthalmus maximus | 71.01 | 3e-86 | 258 |
| LLPS-Leo-1478 | Lepisosteus oculatus | 70.76 | 2e-87 | 261 |
| LLPS-Lac-0808 | Latimeria chalumnae | 70.59 | 6e-86 | 257 |
| LLPS-Tru-1886 | Triticum urartu | 70.18 | 8e-86 | 257 |
| LLPS-Anp-1185 | Anas platyrhynchos | 69.92 | 4e-59 | 187 |
| LLPS-Mea-0771 | Mesocricetus auratus | 67.66 | 2e-80 | 243 |
| LLPS-Chc-0059 | Chondrus crispus | 64.0 | 1e-72 | 223 |
| LLPS-Osl-0490 | Ostreococcus lucimarinus | 62.86 | 2e-77 | 235 |
| LLPS-Chr-0251 | Chlamydomonas reinhardtii | 61.49 | 6e-70 | 216 |
| LLPS-Cym-0370 | Cyanidioschyzon merolae | 57.71 | 4e-60 | 191 |
| LLPS-Loa-2791 | Loxodonta africana | 54.39 | 2e-60 | 192 |
| LLPS-Aon-0185 | Aotus nancymaae | 53.89 | 3e-52 | 171 |