LLPS-Sac-0687
NRP1
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | Asparagine-rich protein |
| Gene Name: | NRP1, ARP, ARP1, YDL167C |
| Ensembl Gene: | YDL167C |
| Ensembl Protein: | YDL167C_mRNA |
| Organism: | Saccharomyces cerevisiae |
| Taxa ID: | 559292 |
| LLPS Type: | Regulator |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| P-body | "...MRNA in P Bodies are joined by a host of protein factors that localize to P Bodies and often have roles in mRNA decapping or translation repression." | N/A | 23224963 |
| Stress granule | "...Genetically induced and stress-induced Nrp1 assemblies are morphologically similar and recruit Pab1." | Saccharomyces cerevisiae | 26238190 |
| Stress granule | "...To the list of proteins identified and validated in stress granules, we added proteins known to be in stress granules but not enriched in our mass spectrometric analysis to create an initial list of yeast stress granule proteins." | Saccharomyces cerevisiae | 26777405 |
| Stress granule | "...We observed that Pub1-mCh colocalized almost completely with GFP fusions of Pab1, eIF4GI, eIF4GII, eIF4E, Pbp1, Ngr1, Eap1, Hrp1, Ygr250c, Gbp2, and Nrp1." | Saccharomyces cerevisiae | 18981231 |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | YDL167C_mRNA | YDL167C_mRNA |
| UniProt | P32770, NRP1_YEAST, D6VRI4, Q12228 | |
| GeneBank | BK006938, X68020, Z74215, Z67750 | CAA98741.1, CAA48159.1, CAA91579.1, DAA11694.1 |
| RefSeq | NM_001180227.1 | NP_010114.1 |
| Entrez | 851387 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MHYVVLELQV AHLPDTPKDQ CRIANIAFQI VNAETLVCHY GTNSLPSIEV NGTTKSLESA 60 61 MVQLDKDIHD VIGNDDFVLV SLYSTWHIRV TLPRQARDDG FILTSYLQHP KVFDLWKEFD 120 121 RWCVNHPEIL GQKKAISNNN CNTKSISINA AKNTKDLDEI VRILEVSIPT EEAGSVPEIY 180 181 SLLKRTTDIL IQLHKKCTSP EDMESVLTKP YDSHTDIRAF LQEKSKILYM NNLPPDTTQS 240 241 ELESWFTQYG VRPVGFWTVK NIVEDTSNVN NNWSLNNSPY VEDQDSISGF VVFQTHEEAT 300 301 EVLALNGRSI LSNLANTKQP RVVEHVLELQ PSSTGVLDKA QEILSPFPQS KNKPRPGDWN 360 361 CPSCGFSNFQ RRTACFRCSF PAPSNSQIHT ANSNNNVNSS RNNLNNRVNS GSSSNISNTA 420 421 ANHPYGAPEF NMIANNTPAA LTYNRAHFPA ITPLSRQNSL NMAPSNSGSP IIIADHFSGN 480 481 NNIAPNYRYN NNINNNNNNI NNMTNNRYNI NNNINGNGNG NGNNSNNNNN HNNNHNNNHH 540 541 NGSINSNSNT NNNNNNNNGN NSNNCNSNIG MGGCGSNMPF RAGDWKCSTC TYHNFAKNVV 600 601 CLRCGGPKSI SGDASETNHY IDSSTFGPAS RTPSNNNISV NTNGGSNAGR TDGNDNKGRD 660 661 ISLMEFMSPP LSMATKSMKE GDGNGSSFNE FKSDKANVNF SNVGDNSAFG NGFNSSIRW 719 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCACTATG TGGTACTAGA GCTGCAAGTT GCGCATTTGC CAGATACCCC CAAGGATCAA 60 61 TGTCGCATTG CGAATATAGC ATTTCAAATT GTGAATGCTG AAACATTAGT ATGCCATTAT 120 121 GGGACCAATT CTTTACCGAG CATTGAAGTA AACGGGACGA CAAAGAGTTT GGAGAGTGCA 180 181 ATGGTGCAAT TGGACAAGGA TATTCATGAC GTTATTGGTA ACGACGACTT TGTTCTTGTT 240 241 TCCCTGTATT CAACATGGCA TATCCGTGTT ACCTTACCAC GTCAAGCGAG AGATGATGGG 300 301 TTTATTCTTA CTTCTTATTT ACAACATCCG AAAGTATTTG ACTTATGGAA GGAATTCGAT 360 361 AGATGGTGTG TCAACCATCC GGAGATTTTG GGACAAAAGA AAGCAATCTC CAACAACAAT 420 421 TGTAATACTA AAAGTATTAG TATTAATGCA GCCAAAAATA CGAAGGATTT GGACGAAATA 480 481 GTTAGAATAT TGGAAGTTTC AATCCCAACT GAAGAGGCAG GCTCTGTTCC AGAGATATAC 540 541 TCTCTTTTAA AAAGGACAAC GGATATATTA ATACAATTGC ACAAAAAGTG TACTTCCCCT 600 601 GAAGATATGG AATCTGTCTT AACAAAACCA TATGACTCAC ACACCGATAT TAGAGCGTTT 660 661 TTGCAAGAGA AATCTAAGAT TTTGTACATG AACAATTTAC CGCCCGACAC AACTCAAAGT 720 721 GAGTTGGAAT CATGGTTTAC CCAATATGGT GTTAGACCAG TTGGGTTTTG GACTGTCAAA 780 781 AACATCGTAG AAGATACGTC TAACGTTAAT AATAACTGGA GTCTAAATAA CAGTCCCTAT 840 841 GTGGAAGATC AAGATAGTAT CTCAGGATTT GTTGTCTTCC AAACACATGA AGAAGCAACT 900 901 GAAGTACTAG CGTTGAATGG GAGATCAATC CTATCTAATC TGGCAAACAC TAAGCAACCA 960 961 AGGGTGGTGG AACATGTCCT TGAGCTTCAA CCTTCTTCCA CCGGAGTACT CGATAAGGCT 1020 1021 CAAGAAATTT TATCGCCTTT CCCTCAAAGT AAAAACAAAC CAAGACCAGG TGACTGGAAT 1080 1081 TGCCCATCTT GTGGTTTTTC AAACTTTCAA AGACGTACTG CATGTTTTAG ATGTTCTTTT 1140 1141 CCGGCACCAT CAAATAGTCA AATACATACT GCGAACTCAA ACAATAATGT TAACAGTAGT 1200 1201 AGAAATAATT TAAACAATCG CGTGAACTCG GGATCTTCAA GCAATATTAG TAACACTGCA 1260 1261 GCGAATCACC CCTATGGTGC CCCTGAGTTC AACATGATTG CTAACAACAC GCCAGCAGCT 1320 1321 TTAACATACA ATAGAGCTCA TTTTCCTGCA ATTACGCCAT TGTCGCGACA AAATTCATTG 1380 1381 AACATGGCAC CATCGAACAG TGGGTCGCCG ATAATTATAG CGGATCATTT TTCGGGAAAT 1440 1441 AATAATATAG CCCCAAATTA TCGTTATAAT AATAATATTA ACAATAACAA CAATAATATT 1500 1501 AACAATATGA CCAATAATAG ATATAACATT AATAACAACA TCAACGGTAA TGGGAATGGT 1560 1561 AATGGGAACA ACAGTAATAA CAATAACAAT CATAATAACA ATCATAATAA CAATCATCAT 1620 1621 AATGGTAGTA TCAATAGTAA TAGTAATACC AATAATAATA ATAATAATAA CAATGGTAAC 1680 1681 AATAGTAATA ATTGTAATTC CAATATCGGT ATGGGAGGAT GTGGCTCCAA CATGCCATTT 1740 1741 AGAGCAGGAG ATTGGAAGTG TTCCACGTGC ACGTATCATA ACTTTGCTAA AAACGTAGTG 1800 1801 TGCTTACGCT GTGGTGGTCC AAAATCAATA AGCGGCGATG CAAGTGAAAC CAATCATTAC 1860 1861 ATAGATTCAT CAACATTTGG ACCAGCGTCG CGTACTCCCA GTAATAACAA TATTTCTGTT 1920 1921 AATACTAATG GTGGTAGCAA TGCTGGTCGC ACCGATGGGA ACGATAACAA AGGTCGTGAT 1980 1981 ATTAGTTTGA TGGAATTTAT GTCACCACCG TTATCGATGG CAACAAAGTC AATGAAGGAG 2040 2041 GGAGATGGGA ATGGTAGCTC GTTTAACGAG TTCAAAAGTG ACAAAGCTAA CGTTAATTTT 2100 2101 TCCAATGTTG GTGATAATAG CGCTTTCGGT AATGGTTTTA ATAGTTCAAT ACGTTGGTAG 2160 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Beb-1536 | Beauveria bassiana | 76.67 | 4e-07 | 57.8 |
| LLPS-Asf-0263 | Aspergillus flavus | 70.59 | 2e-08 | 61.2 |
| LLPS-Asni-1065 | Aspergillus niger | 70.59 | 3e-08 | 61.2 |
| LLPS-Asn-0917 | Aspergillus nidulans | 70.59 | 3e-08 | 61.2 |
| LLPS-Asc-1689 | Aspergillus clavatus | 70.59 | 3e-08 | 61.2 |
| LLPS-Asfu-1231 | Aspergillus fumigatus | 70.59 | 3e-08 | 61.2 |
| LLPS-Nef-1407 | Neosartorya fischeri | 70.59 | 3e-08 | 61.2 |
| LLPS-Ast-1384 | Aspergillus terreus | 70.59 | 3e-08 | 61.2 |
| LLPS-Tum-0326 | Tuber melanosporum | 67.65 | 3e-07 | 57.8 |
| LLPS-Blg-1468 | Blumeria graminis | 67.65 | 2e-07 | 58.9 |
| LLPS-Kop-1031 | Komagataella pastoris | 64.71 | 2e-07 | 58.9 |
| LLPS-Scj-0352 | Schizosaccharomyces japonicus | 63.89 | 2e-07 | 58.9 |
| LLPS-Scp-1556 | Schizosaccharomyces pombe | 62.16 | 3e-07 | 58.2 |
| LLPS-Scc-0508 | Schizosaccharomyces cryophilus | 62.16 | 4e-07 | 57.8 |
| LLPS-Asg-0317 | Ashbya gossypii | 59.64 | 1e-143 | 441 |
| LLPS-Yal-0919 | Yarrowia lipolytica | 54.17 | 1e-07 | 58.9 |
| LLPS-Coo-0719 | Colletotrichum orbiculare | 53.33 | 8e-08 | 59.7 |
| LLPS-Mao-0425 | Magnaporthe oryzae | 52.38 | 2e-06 | 55.8 |
| LLPS-Fuv-1319 | Fusarium verticillioides | 52.27 | 3e-07 | 58.2 |
| LLPS-Scs-1037 | Sclerotinia sclerotiorum | 52.27 | 3e-07 | 58.2 |
| LLPS-Fuo-1582 | Fusarium oxysporum | 52.27 | 2e-07 | 58.2 |
| LLPS-Fus-0207 | Fusarium solani | 52.27 | 3e-07 | 58.2 |
| LLPS-Gag-0138 | Gaeumannomyces graminis | 52.08 | 9e-07 | 56.6 |
| LLPS-Dos-0285 | Dothistroma septosporum | 50.91 | 4e-07 | 57.8 |
| LLPS-Map-0565 | Magnaporthe poae | 49.18 | 2e-07 | 58.9 |
| LLPS-Lem-1222 | Leptosphaeria maculans | 45.71 | 4e-07 | 57.4 |
| LLPS-Pyt-0129 | Pyrenophora teres | 45.07 | 3e-07 | 57.8 |
| LLPS-Pytr-0156 | Pyrenophora triticirepentis | 45.07 | 2e-07 | 58.9 |
| LLPS-Nec-1227 | Neurospora crassa | 43.87 | 6e-76 | 263 |
| LLPS-Trr-0905 | Trichoderma reesei | 43.87 | 1e-76 | 265 |
| LLPS-Zyt-1505 | Zymoseptoria tritici | 43.66 | 2e-07 | 58.5 |
| LLPS-Cogr-1541 | Colletotrichum graminicola | 43.66 | 8e-08 | 60.1 |
| LLPS-Trv-0810 | Trichoderma virens | 43.55 | 1e-75 | 262 |
| LLPS-Cog-1491 | Colletotrichum gloeosporioides | 43.22 | 4e-76 | 257 |
| LLPS-Ved-1124 | Verticillium dahliae | 43.17 | 5e-75 | 261 |
| LLPS-Phn-0607 | Phaeosphaeria nodorum | 41.77 | 1e-76 | 264 |
| LLPS-Aso-0273 | Aspergillus oryzae | 40.54 | 3e-75 | 261 |
| LLPS-Abg-1810 | Absidia glauca | 30.87 | 1e-41 | 167 |