LLPS-Rhb-a1136
GDI1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Rab GDP dissociation inhibitor |
| Gene Name: | GDI1 |
| Ensembl Gene: | ENSRBIG00000042799.1 |
| Ensembl Protein: | ENSRBIP00000038587.1 |
| Organism: | Rhinopithecus bieti |
| Taxa ID: | 61621 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSRBIT00000062605.1 | ENSRBIP00000038587.1 |
| Ensembl | ENSRBIT00000062609.1 | ENSRBIP00000038591.1 |
| Ensembl | ENSRBIT00000062606.1 | ENSRBIP00000038588.1 |
| UniProt | A0A2K6MS67, A0A2K6MS67_RHIBE | |
| RefSeq | XM_017857383.1 | XP_017712872.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MEPPPAAAAA RVRTAAGPPP PAPPELSGTL GEANVPAERA GAVAGPWQAS REAAGKAVFP 60 61 AGGGGARERR DSLTRRRGRD GGTRAIFGPV RGGGGGVVAT AAVKEEEEPT GRCPPRPDHG 120 121 REYDVIGAEG PDLTPVGVVG GRSCPLRQIW VGNKSGLLVG AEAGGSAADC VALPQECILS 180 181 GIMSVNGKKV LHMDRNPYYG GESSSITPLE ELYKRFQLLE GPPESMGRGR DWNVDLIPKF 240 241 LMANGQLVKM LLYTEVTRYL DFKVVEGSFV YKGGKIYKVP STETEALASN LMGMFEKRRF 300 301 RKFLVFVANF DENDPKTFEG VDPQTTSMRD VYRKFDLGQD VIDFTGHALA LYRTDDYLDQ 360 361 PCLETINRIK LYSESLARYG KSPYLYPLYG LGELPQGFAR LSAIYGGTYM LNKPVDDIIM 420 421 ENGKVVGVKS EGEVARCKQL ICDPSYIPDR VRKAGQVIRI ICILSHPIKN TNDANSCQII 480 481 IPQNQVNRKS DIYVCMISYA HNVAAQGKYI AIASTTVETT DPEKEVEPAL ELLEPIDQKF 540 541 VAISDLYEPI DDGCESQVFC SCSYDATTHF ETTCNDIKDI YKRMAGMAFD FENMKRKQND 600 601 VFGEAEQ 607 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Cellular Component | Midbody | |
Molecular Function | GTPase activator activity | |
Molecular Function | Rab GDP-dissociation inhibitor activity | |
Biological Process | Negative regulation of protein targeting to membrane | |
Biological Process | Protein transport | |
Biological Process | Small GTPase mediated signal transduction |