• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Rhb-3669
VPS4B

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: VPS4B
Ensembl Gene: ENSRBIG00000036906.1
Ensembl Protein: ENSRBIP00000026050.1
Organism: Rhinopithecus bieti
Taxa ID: 61621
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSSTSPNLQK  AIDLASKAAQ  EDKAGNYEEA  LQLYQHAVQY  FLHVVKYEAQ  GDKAKQSIRA  60
61    KCTEYLDRAE  KLKEYLKNKE  KKAQKPVKEG  QPSPADEKGN  DSDGEGESDD  PEKKKLQNQL  120
121   QGAIVIERPN  VKWSDVAGLE  GAKEALKEAV  ILPIKFPHLF  TGKRTPWRGI  LLFGPPGTGK  180
181   SYLAKAVATE  ANNSTFFSIS  SSDLVSKWLG  ESEKLVKNLF  QLARENKPSI  IFIDEIDSLC  240
241   GSRSENESEA  ARRIKTEFLV  QMQGVGVDND  GILVLGATNI  PWVLDSAIRR  RFEKRIYIPL  300
301   PEPHARAAMF  KLHLGTTQNS  LTEADFRELG  KKTDGYSGAD  ISIIVRDALM  QPVRKVQSAT  360
361   HFKKVRGPSR  ADPNHLVDDL  LTPCSPGDPG  AIEMTWMDVP  GDKLLEPVVS  MSDMLRSLSN  420
421   TKPTVNEHDL  LKLKKFTEDF  GQEG  444
Nucleotide CDS Sequence (FASTA)
1     ATGTCATCCA  CTTCGCCCAA  CCTCCAGAAA  GCGATAGATC  TGGCTAGCAA  AGCAGCGCAA  60
61    GAAGACAAGG  CTGGGAACTA  CGAAGAAGCC  CTTCAGCTCT  ACCAGCATGC  TGTGCAGTAT  120
121   TTTCTTCATG  TCGTGAAATA  TGAAGCACAG  GGTGATAAAG  CCAAGCAAAG  TATCAGGGCA  180
181   AAGTGTACAG  AATATCTTGA  TAGAGCAGAA  AAACTAAAGG  AGTACCTGAA  AAATAAAGAG  240
241   AAAAAAGCAC  AGAAGCCAGT  GAAAGAAGGA  CAGCCGAGTC  CAGCAGATGA  GAAGGGGAAT  300
301   GACAGTGATG  GGGAAGGAGA  ATCTGATGAT  CCTGAAAAAA  AGAAACTACA  GAATCAACTT  360
361   CAAGGTGCTA  TTGTTATAGA  ACGACCAAAT  GTGAAATGGA  GTGATGTTGC  TGGACTTGAA  420
421   GGAGCCAAAG  AAGCACTGAA  AGAGGCTGTG  ATACTGCCTA  TTAAATTTCC  TCATCTTTTT  480
481   ACAGGGAAGA  GAACACCTTG  GAGGGGAATC  CTATTATTTG  GGCCGCCTGG  AACAGGAAAG  540
541   TCCTACTTAG  CCAAAGCTGT  AGCAACAGAA  GCCAACAACT  CAACATTTTT  TTCAATATCT  600
601   TCCTCTGATC  TTGTTTCTAA  GTGGCTAGGT  GAAAGTGAAA  AACTGGTTAA  GAATTTATTC  660
661   CAACTTGCCA  GAGAGAACAA  GCCTTCCATT  ATCTTCATTG  ATGAAATTGA  TTCTCTGTGT  720
721   GGTTCAAGAA  GTGAAAACGA  AAGTGAAGCC  GCACGTAGAA  TTAAGACGGA  GTTCCTAGTG  780
781   CAAATGCAAG  GGGTTGGTGT  AGACAATGAT  GGAATTTTGG  TTCTGGGAGC  TACAAATATA  840
841   CCCTGGGTTC  TGGATTCTGC  CATTAGGCGA  AGATTTGAGA  AACGAATTTA  TATTCCTTTG  900
901   CCGGAACCCC  ATGCCCGAGC  AGCAATGTTT  AAACTGCACC  TGGGGACCAC  TCAGAACAGT  960
961   CTTACAGAAG  CAGACTTTCG  GGAACTTGGG  AAGAAAACAG  ATGGTTATTC  AGGGGCAGAT  1020
1021  ATAAGTATCA  TTGTACGTGA  TGCACTTATG  CAGCCTGTTA  GGAAAGTACA  GTCAGCTACT  1080
1081  CATTTTAAAA  AGGTTCGCGG  ACCTTCCCGA  GCTGATCCTA  ACCATCTTGT  AGATGATCTG  1140
1141  CTAACACCTT  GCTCTCCAGG  TGACCCTGGT  GCCATTGAAA  TGACATGGAT  GGATGTCCCT  1200
1201  GGAGATAAAC  TTTTGGAGCC  AGTTGTTTCC  ATGTCAGATA  TGTTGCGGTC  ACTATCTAAC  1260
1261  ACAAAACCTA  CAGTCAATGA  ACATGACTTG  TTGAAATTAA  AGAAGTTTAC  AGAAGATTTT  1320
1321  GGTCAAGAAG  GCTAA  1335

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cea-0596Cercocebus atys99.770.0 825
LLPS-Maf-4387Macaca fascicularis99.770.0 824
LLPS-Chs-4788Chlorocebus sabaeus99.770.0 829
LLPS-Mal-2989Mandrillus leucophaeus99.770.0 829
LLPS-Man-2082Macaca nemestrina99.770.0 824
LLPS-Hos-3929Homo sapiens99.770.0 829
LLPS-Pap-1976Pan paniscus99.770.0 810
LLPS-Pat-3891Pan troglodytes99.770.0 810
LLPS-Mam-3409Macaca mulatta99.770.0 829
LLPS-Poa-3996Pongo abelii99.770.0 829
LLPS-Gog-3079Gorilla gorilla99.550.0 828
LLPS-Paa-0064Papio anubis99.550.0 823
LLPS-Caj-4624Callithrix jacchus99.540.0 807
LLPS-Aon-1898Aotus nancymaae99.310.0 806
LLPS-Nol-4462Nomascus leucogenys98.870.0 807
LLPS-Fud-2888Fukomys damarensis97.070.0 809
LLPS-Dio-0504Dipodomys ordii97.070.0 798
LLPS-Bot-4434Bos taurus96.850.0 807
LLPS-Ova-1169Ovis aries96.170.0 806
LLPS-Loa-3516Loxodonta africana95.950.0 798
LLPS-Cap-4162Cavia porcellus95.50.0 797
LLPS-Ere-0016Erinaceus europaeus93.720.0 712
LLPS-Pes-0723Pelodiscus sinensis90.340.0 741
LLPS-Gaga-3964Gallus gallus90.230.0 737
LLPS-Fia-0651Ficedula albicollis90.160.0 738
LLPS-Tag-2911Taeniopygia guttata89.470.0 732
LLPS-Anp-3138Anas platyrhynchos88.690.0 736
LLPS-Meg-3132Meleagris gallopavo87.470.0 738
LLPS-Dar-0802Danio rerio86.240.0 723
LLPS-Icp-1474Ictalurus punctatus84.910.0 721
LLPS-Scm-3733Scophthalmus maximus83.60.0 704
LLPS-Orn-1902Oreochromis niloticus83.410.0 712
LLPS-Gaa-2483Gasterosteus aculeatus83.30.0 707
LLPS-Xim-3389Xiphophorus maculatus82.50.0 705
LLPS-Pof-2988Poecilia formosa82.50.0 704
LLPS-Anc-0212Anolis carolinensis81.860.0 693
LLPS-Asm-0401Astyanax mexicanus81.460.0 694
LLPS-Otg-0663Otolemur garnettii81.190.0 689
LLPS-Tar-0557Takifugu rubripes80.920.0 684
LLPS-Ten-3539Tetraodon nigroviridis80.780.0 682
LLPS-Leo-1432Lepisosteus oculatus80.730.0 697
LLPS-Scf-0592Scleropages formosus80.730.0 694
LLPS-Sah-1239Sarcophilus harrisii80.50.0 686
LLPS-Mea-3071Mesocricetus auratus80.50.0 683
LLPS-Urm-0919Ursus maritimus80.460.0 684
LLPS-Mum-1587Mus musculus80.450.0 689
LLPS-Ran-0091Rattus norvegicus80.450.0 690
LLPS-Orc-0586Oryctolagus cuniculus80.450.0 690
LLPS-Cas-0902Carlito syrichta80.450.0 689
LLPS-Aim-2510Ailuropoda melanoleuca80.320.0 687
LLPS-Myl-2869Myotis lucifugus80.280.0 685
LLPS-Sus-0550Sus scrofa80.230.0 691
LLPS-Mup-2478Mustela putorius furo80.230.0 691
LLPS-Ict-3080Ictidomys tridecemlineatus80.230.0 688
LLPS-Caf-0571Canis familiaris80.180.0 688
LLPS-Eqc-1220Equus caballus79.90.0 636
LLPS-Fec-0830Felis catus79.770.0 687
LLPS-Mod-1502Monodelphis domestica79.510.0 691
LLPS-Lac-0057Latimeria chalumnae79.450.0 687
LLPS-Ora-0436Ornithorhynchus anatinus79.410.0 683
LLPS-Xet-0204Xenopus tropicalis79.140.0 696
LLPS-Tut-1477Tursiops truncatus78.340.0 680
LLPS-Orl-3324Oryzias latipes78.00.0 675
LLPS-Put-0907Puccinia triticina76.362e-84 266
LLPS-Drm-1454Drosophila melanogaster73.970.0 627
LLPS-Cis-1612Ciona savignyi72.652e-117 349
LLPS-Cii-1044Ciona intestinalis68.040.0 593
LLPS-Cae-0121Caenorhabditis elegans66.740.0 590
LLPS-Hov-0585Hordeum vulgare60.782e-138 414
LLPS-Asg-0429Ashbya gossypii60.727e-169 489
LLPS-Pug-0580Puccinia graminis60.591e-173 501
LLPS-Sac-1212Saccharomyces cerevisiae60.58e-173 499
LLPS-Mel-0130Melampsora laricipopulina60.363e-170 493
LLPS-Crn-0895Cryptococcus neoformans60.279e-166 481
LLPS-Kop-0338Komagataella pastoris60.189e-175 504
LLPS-Tum-1042Tuber melanosporum59.452e-167 485
LLPS-Nec-1292Neurospora crassa59.021e-168 488
LLPS-Miv-1422Microbotryum violaceum58.742e-167 486
LLPS-Blg-0019Blumeria graminis58.373e-168 488
LLPS-Scp-1222Schizosaccharomyces pombe58.242e-159 464
LLPS-Cym-0316Cyanidioschyzon merolae57.783e-126 384
LLPS-Asf-0380Aspergillus flavus57.664e-168 487
LLPS-Dos-0949Dothistroma septosporum57.663e-165 480
LLPS-Asc-0067Aspergillus clavatus57.437e-169 489
LLPS-Ast-0832Aspergillus terreus57.433e-169 490
LLPS-Yal-0634Yarrowia lipolytica57.186e-165 479
LLPS-Asfu-0833Aspergillus fumigatus57.175e-169 489
LLPS-Lem-0542Leptosphaeria maculans57.143e-160 467
LLPS-Scc-1154Schizosaccharomyces cryophilus57.114e-157 459
LLPS-Spr-0962Sporisorium reilianum57.051e-167 487
LLPS-Asni-0022Aspergillus niger56.983e-168 488
LLPS-Nef-0231Neosartorya fischeri56.953e-168 487
LLPS-Asn-0968Aspergillus nidulans56.794e-170 492
LLPS-Chr-1513Chlamydomonas reinhardtii56.493e-162 472
LLPS-Aso-1228Aspergillus oryzae56.436e-166 482
LLPS-Mao-0131Magnaporthe oryzae56.224e-159 464
LLPS-Scj-1478Schizosaccharomyces japonicus56.214e-158 462
LLPS-Usm-0594Ustilago maydis56.211e-166 484
LLPS-Gas-0335Galdieria sulphuraria56.082e-161 471
LLPS-Beb-1235Beauveria bassiana55.868e-149 438
LLPS-Pytr-0885Pyrenophora triticirepentis55.73e-155 454
LLPS-Cog-0741Colletotrichum gloeosporioides55.617e-155 453
LLPS-Cogr-1560Colletotrichum graminicola55.583e-152 447
LLPS-Zem-2303Zea mays55.433e-152 447
LLPS-Chc-0879Chondrus crispus55.386e-148 436
LLPS-Coo-1010Colletotrichum orbiculare55.364e-153 449
LLPS-Gag-0359Gaeumannomyces graminis55.312e-148 438
LLPS-Sob-1314Sorghum bicolor55.32e-154 452
LLPS-Fus-0219Fusarium solani55.058e-149 438
LLPS-Fuv-1141Fusarium verticillioides54.946e-149 438
LLPS-Trr-0807Trichoderma reesei54.942e-150 442
LLPS-Fuo-0279Fusarium oxysporum54.948e-149 438
LLPS-Orni-0044Oryza nivara54.882e-143 437
LLPS-Pyt-0568Pyrenophora teres54.812e-150 442
LLPS-Trv-0993Trichoderma virens54.714e-150 441
LLPS-Ved-0260Verticillium dahliae54.715e-156 456
LLPS-Orbr-1690Oryza brachyantha54.652e-149 439
LLPS-Zyt-0226Zymoseptoria tritici54.638e-159 463
LLPS-Dac-0537Daucus carota54.595e-147 433
LLPS-Orr-2069Oryza rufipogon54.443e-144 438
LLPS-Mua-2472Musa acuminata54.421e-153 449
LLPS-Bro-0918Brassica oleracea54.422e-149 439
LLPS-Php-1576Physcomitrella patens54.341e-150 443
LLPS-Glm-2644Glycine max54.283e-147 434
LLPS-Orb-0309Oryza barthii54.21e-144 439
LLPS-Ori-0496Oryza indica54.21e-149 440
LLPS-Orgl-1181Oryza glumaepatula54.27e-145 439
LLPS-Orp-1303Oryza punctata54.21e-149 440
LLPS-Brr-2381Brassica rapa54.24e-147 434
LLPS-Org-1671Oryza glaberrima54.21e-149 440
LLPS-Tra-0488Triticum aestivum54.167e-154 451
LLPS-Map-0592Magnaporthe poae54.113e-155 455
LLPS-Hea-2551Helianthus annuus53.972e-146 432
LLPS-Viv-0676Vitis vinifera53.956e-150 441
LLPS-Arl-2110Arabidopsis lyrata53.933e-149 439
LLPS-Pot-2026Populus trichocarpa53.93e-151 444
LLPS-Amt-0912Amborella trichopoda53.724e-149 439
LLPS-Brd-1758Brachypodium distachyon53.715e-152 446
LLPS-Art-2900Arabidopsis thaliana53.711e-148 437
LLPS-Sei-2178Setaria italica53.641e-152 447
LLPS-Sem-1833Selaginella moellendorffii53.62e-146 432
LLPS-Brn-2430Brassica napus53.511e-148 437
LLPS-Nia-2320Nicotiana attenuata53.512e-149 439
LLPS-Sol-2004Solanum lycopersicum53.361e-144 427
LLPS-Mae-1865Manihot esculenta53.231e-149 440
LLPS-Thc-2121Theobroma cacao53.192e-150 442
LLPS-Lep-2095Leersia perrieri52.831e-144 427
LLPS-Osl-0483Ostreococcus lucimarinus52.831e-140 417
LLPS-Via-0535Vigna angularis52.825e-143 423
LLPS-Phv-0788Phaseolus vulgaris52.811e-141 420
LLPS-Vir-0212Vigna radiata52.64e-142 421
LLPS-Coc-0217Corchorus capsularis52.533e-149 439
LLPS-Sot-1975Solanum tuberosum52.384e-144 426
LLPS-Ors-0361Oryza sativa52.384e-142 421
LLPS-Orm-0701Oryza meridionalis52.389e-140 415
LLPS-Gor-0325Gossypium raimondii52.318e-149 438
LLPS-Cus-1022Cucumis sativus52.112e-146 432
LLPS-Prp-0208Prunus persica52.119e-150 440
LLPS-Met-0938Medicago truncatula50.881e-143 425
LLPS-Phn-0529Phaeosphaeria nodorum49.336e-130 390
LLPS-Tru-1948Triticum urartu45.881e-137 412