LLPS-Ran-a124
Gnb1
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Transducin beta chain 1 |
| Gene Name: | Gnb1 |
| Ensembl Gene: | ENSRNOG00000016638.5 |
| Ensembl Protein: | ENSRNOP00000044340.2 |
| Organism: | Rattus norvegicus |
| Taxa ID: | 10116 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSRNOT00000041789.2 | ENSRNOP00000044340.2 |
| UniProt | P54311, GBB1_RAT, Q6Q8B1, Q9QWG8 | |
| GeneBank | U88324, BC078809, AY552805, U34958 | AAC72249.1, AAS59143.1, AAH78809.1, AAD00650.1 |
| RefSeq | NM_030987.2, XM_006239517.3, XM_008764335.2, XM_017593145.1, XM_017593146.1, XM_017593147.1, XM_017593148.1, XM_017593149.1 | NP_112249.2, XP_006239579.1, XP_008762557.1, XP_017448634.1, XP_017448635.1, XP_017448636.1, XP_017448637.1, XP_017448638.1 |
| Entrez | 24400 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSELDQLRQE AEQLKNQIRD ARKACADATL SQITNNIDPV GRIQMRTRRT LRGHLAKIYA 60 61 MHWGTDSRLL VSASQDGKLI IWDSYTTNKV HAIPLRSSWV MTCAYAPSGN YVACGGLDNI 120 121 CSIYNLKTRE GNVRVSRELA GHTGYLSCCR FLDDNQIVTS SGDTTCALWD IETGQQTTTF 180 181 TGHTGDVMSL SLAPDTRLFV SGACDASAKL WDVREGMCRQ TFTGHESDIN AICFFPNGNA 240 241 FATGSDDATC RLFDLRADQE LMTYSHDNII CGITSVSFSK SGRLLLAGYD DFNCNVWDAL 300 301 KADRAGVLAG HDNRVSCLGV TDDGMAVATG SWDSFLKIWN 340 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGTGAAC TTGACCAGCT GCGGCAGGAG GCCGAGCAAC TGAAGAACCA AATTAGAGAT 60 61 GCCCGTAAAG CATGTGCAGA TGCGACTCTT TCTCAGATCA CAAACAACAT TGATCCAGTG 120 121 GGAAGAATCC AAATGCGAAC CAGGAGAACA CTGAGGGGGC ATCTGGCAAA GATTTATGCC 180 181 ATGCACTGGG GCACAGACTC AAGGCTCCTT GTCAGCGCCT CTCAGGATGG GAAACTCATC 240 241 ATCTGGGACA GCTATACCAC AAACAAGGTT CATGCCATCC CTCTGCGCTC CTCTTGGGTC 300 301 ATGACCTGTG CATACGCTCC TTCTGGGAAT TATGTGGCCT GTGGTGGCCT GGATAACATC 360 361 TGCTCCATTT ACAATCTGAA AACTCGTGAA GGAAATGTGC GTGTGAGTCG TGAGCTGGCA 420 421 GGACATACAG GTTATCTATC CTGTTGCCGG TTCCTGGATG ACAATCAGAT AGTTACCAGT 480 481 TCTGGAGACA CCACATGTGC CCTGTGGGAC ATCGAGACCG GCCAGCAGAC AACCACGTTT 540 541 ACTGGACACA CTGGAGATGT CATGAGCCTG TCTCTTGCTC CTGACACCAG ACTGTTTGTC 600 601 TCTGGTGCTT GCGATGCTTC GGCCAAGCTC TGGGATGTCC GAGAAGGGAT GTGCCGGCAG 660 661 ACCTTTACAG GACACGAGTC TGACATCAAT GCCATATGTT TCTTTCCCAA TGGCAATGCC 720 721 TTTGCCACTG GCTCAGACGA TGCTACATGC AGGCTGTTTG ACCTTCGTGC AGACCAGGAG 780 781 CTCATGACCT ACTCCCATGA CAACATTATC TGTGGTATCA CATCTGTTTC CTTCTCCAAG 840 841 AGTGGCCGCC TCCTCCTCGC TGGCTATGAC GACTTCAACT GTAATGTCTG GGATGCACTC 900 901 AAAGCTGACA GAGCAGGTGT CCTAGCTGGA CATGACAACC GAGTCAGCTG CTTGGGGGTG 960 961 ACTGATGATG GCATGGCTGT GGCAACAGGA TCCTGGGACA GCTTCCTCAA GATCTGGAAC 1020 1021 TAA 1023 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cell body | |
Cellular Component | Dendrite | |
Cellular Component | Heterotrimeric G-protein complex | |
Cellular Component | Photoreceptor inner segment | |
Cellular Component | Photoreceptor outer segment membrane | |
Molecular Function | Alkylglycerophosphoethanolamine phosphodiesterase activity | |
Molecular Function | GTPase activity | |
Molecular Function | GTPase binding | |
Molecular Function | Protein-containing complex binding | |
Molecular Function | Spectrin binding | |
Biological Process | Cardiac muscle cell apoptotic process | |
Biological Process | Cell population proliferation | |
Biological Process | Cellular response to hypoxia | |
Biological Process | G protein-coupled receptor signaling pathway | |
Biological Process | Phospholipase C-activating G protein-coupled receptor signaling pathway | |
Biological Process | Positive regulation of cytosolic calcium ion concentration | |
Biological Process | Protein heterotrimerization | |
Biological Process | Retina development in camera-type eye | |
Biological Process | Sensory perception of taste |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Structure | ||||
| PDB | ||||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | TISSUES | |||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a123 | Homo sapiens | 0.0 | 703 | undefined |
| LLPS-Mum-a125 | Mus musculus | 0.0 | 703 | undefined |