LLPS-Ran-a1185
Atp5mf
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | ATP synthase subunit f, mitochondrial; ATP synthase membrane subunit f |
| Gene Name: | Atp5mf, Atp5j2 |
| Ensembl Gene: | ENSRNOG00000027049.6 |
| Ensembl Protein: | ENSRNOP00000029426.3 |
| Organism: | Rattus norvegicus |
| Taxa ID: | 10116 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSRNOT00000033537.5 | ENSRNOP00000029426.3 |
| UniProt | D3ZAF6, ATPK_RAT | |
| RefSeq | NM_001271117.1 | NP_001258046.1 |
| Entrez | 690441 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MASIVPLKEK KLMEVKLREL PSWILMRDFT PSGIAGAFRR GYDRYYNKYI NVRKGSISGI 60 61 NMVLAAYVVF SYCISYKELK HERRRKYH 88 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGTCTA TCGTGCCATT GAAGGAGAAG AAGCTCATGG AGGTTAAACT TAGAGAGCTG 60 61 CCAAGCTGGA TATTGATGCG GGATTTCACC CCCAGTGGTA TTGCAGGAGC CTTTCGGAGA 120 121 GGCTATGACC GGTATTACAA CAAGTACATC AACGTTCGGA AAGGCAGCAT CTCAGGGATT 180 181 AACATGGTGC TGGCAGCCTA CGTGGTTTTC AGCTACTGCA TTTCTTACAA GGAACTCAAA 240 241 CACGAACGGC GACGCAAGTA CCACTGA 267 |
▼ KEYWORD
ID | Family |
Acetylation | |
ATP synthesis | |
CF(0) | |
Complete proteome | |
Hydrogen ion transport | |
Ion transport | |
Membrane | |
Mitochondrion | |
Mitochondrion inner membrane | |
Phosphoprotein | |
Reference proteome | |
Transmembrane | |
Transmembrane helix | |
Transport
|
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Integral component of membrane | |
Cellular Component | Mitochondrial proton-transporting ATP synthase complex | |
Cellular Component | Mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) | |
Molecular Function | ATPase activity | |
Biological Process | ATP biosynthetic process | |
Biological Process | ATP metabolic process | |
Biological Process | Ion transport |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| CORUM | ||||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | TISSUES | |||