LLPS-Ran-a067
Rimbp2
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | RIMS-binding protein 2 |
| Gene Name: | Rimbp2, Rbp2 |
| Ensembl Gene: | ENSRNOG00000022893.7 |
| Ensembl Protein: | ENSRNOP00000030915.4 |
| Organism: | Rattus norvegicus |
| Taxa ID: | 10116 |
| LLPS Type: | Others |
▼ PROPERTY
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSRNOT00000033379.4 | ENSRNOP00000030915.4 |
| Ensembl | ENSRNOT00000086078.1 | ENSRNOP00000073070.1 |
| Ensembl | ENSRNOT00000067867.4 | ENSRNOP00000059643.1 |
| UniProt | Q9JIR1, RIMB2_RAT | |
| GeneBank | AABR03082706, AF199336, AABR03082432, AABR03082106 | , AAF81658.1 |
| Entrez | 266780 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MNGLATSIHK GHEGPTGHYS VIGDYIPLSG DKLESPCVKP SFLLRSSSPR CRFESEMDDD 60 61 RSSNKSKHSS SGKVHLCVAR YSYNPFDGPN ENPEAELPLT AGKYLYVYGD MDEDGFYEGE 120 121 LLDGQRGLVP SNFVDFIQDN ESRFAGTLGS EQDQNFLNHS GISLERDSIL HLHSPTQVDS 180 181 GITDNGGGTL DVNIDDIGED IVPYPRKITL IKQLAKSVIV GWEPPAVPPG WGTVSSYNVL 240 241 VDKETRMSLA LGRRTKALIE KLNTAACTYR ISVQCVTSRG NSDELQCTLL VGKDVVVAPS 300 301 QLRVDNITQI SAQLSWLPTN SNYSHIIFLN EEELDIVKAA RYKYQFFNLR PNMAYKVKVL 360 361 AQPHQMPWQL PLEQREKKEA CVEFSTLPAG PPAPPQDVTV QAGATTASVQ VSWKPPALTP 420 421 TGLSNGANVT GYGVYAKGQR VAEVIAPTAD GAAVELVRLR SLEAKAVSVR TLSAQGESMD 480 481 SALAAIPPDL LVPPAPHPRT APPPKPLASD MDTKDLGPHV KVDESWEQSR PPGPAHGHML 540 541 EPPDMHSTGP GRRSPSPSRI LPQPQGAPVS TTVAKAMARE AAQRVAESNR LEKRSLFLEQ 600 601 SSAGPYANSD EEDGYASPEV KRRGTSVDDF LKGSELGQQP HCCHGDEYHT ESSRGSDLSD 660 661 IMEEDEEELY SEMQLEDGGR RRPSGTSHNA LKEYHKARSL EGAFLEQPEF PQQPHRSKRL 720 721 FSIPEVAEED AEHGEPLLRQ GMGSSRARAL LAMERGPARS CWGHPVLQGS WLPAEHRGPG 780 781 IYMEDLFLED RGCRFSRSAT RSPDSGLDCG SEEEESRFSF RSTSAKCSPG PGHCPCRRSP 840 841 RPLLARRRTL TRQSSIEEDF GEQVDPSDVI RSDDTQPSPE RPVPRRDGWD EASDHEDFRG 900 901 VWRKSPAMPD SRAAERLTQP PPRVADGPLI LGNSALMGRG DRMEHVSRRY SHSGGGPQRH 960 961 RPMAPSIDEY TGRDHLSPDF YDESETDPGA EELPARIFVA LFDYDPLTMS PNPDAAEEEL 1020 1021 PFKEGQIIKV YGDKDADGFY RGETCARLGL IPCNMVSEIH ADDEEMMDQL LRQGFLPLNT 1080 1081 PVEKIERSRR SGRGHSVPTR RMVALYDYDP RESSPNVDVE AELLFCTGDI ITVFGEIDED 1140 1141 GFYYGELNGQ KGLVPSNFLE EVPDDVEVHL SDAPPHYSHD PPMRTKAKRV ASKNMKAKKN 1200 1201 HGGACRVSVQ VSLNRTTCFY PSWLFGPLRQ GCGTLLLC 1238 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCGAGAGG CTGCTGAGCG AAGGCAACAG CTGGAGTTGG AGCATGAGCA AGCCCTGGCC 60 61 ATTCTCAATG CCAAGCAGCA GGAGATCCAG CTTCTGCAGC AGTCCAAGGT CCGAGAGCTG 120 121 GAAGAGAAAT GCCGTGTGCA AAGCGAGCAG TTTAACCTGT TGTCCCGGGA CCTGGAGAAG 180 181 TTCCGGCAAC ACGCTGGGAG TATTGACCTG CTGGGAAGCA ACTCAGTGGC CTTGCTGGAT 240 241 GTCCCTCTGG CCCCTGGCAA GCCTTTCTCA CAGTACATGA ATGGACTAGC CACTTCCATC 300 301 CACAAAGGTC ACGAGGGCCC CACCGGACAC TACTCTGTGA TTGGTGACTA TATCCCGCTG 360 361 TCTGGGGACA AGCTGGAGTC TCCGTGTGTG AAGCCCTCCT TCCTGTTGAG ATCCAGCAGC 420 421 CCAAGATGCA GATTTGAGTC CGAGATGGAC GATGACCGGA GCTCTAACAA GTCCAAGCAC 480 481 AGCAGCTCGG GGAAGGTGCA CCTGTGTGTG GCCCGCTACA GTTACAACCC CTTCGATGGG 540 541 CCCAATGAGA ACCCGGAAGC GGAGCTGCCT CTCACGGCGG GAAAGTATCT CTACGTCTAT 600 601 GGGGACATGG ATGAAGATGG GTTCTACGAA GGAGAACTTT TGGATGGGCA GAGGGGCTTG 660 661 GTGCCGTCCA ACTTTGTGGA TTTTATCCAG GACAACGAGT CACGGTTCGC TGGCACTCTG 720 721 GGGAGTGAGC AGGACCAGAA CTTTCTCAAC CACTCTGGCA TCAGTCTGGA ACGCGACAGC 780 781 ATCCTTCACC TCCACTCTCC AACTCAAGTG GACTCGGGGA TCACTGACAA TGGTGGGGGA 840 841 ACCCTGGACG TGAACATCGA TGACATCGGA GAAGACATTG TGCCTTACCC TAGGAAAATC 900 901 ACCCTCATCA AACAGCTTGC CAAAAGTGTC ATCGTGGGCT GGGAGCCCCC TGCCGTGCCT 960 961 CCCGGCTGGG GCACCGTGAG CAGTTATAAT GTGCTGGTGG ACAAAGAGAC ACGAATGAGC 1020 1021 CTTGCCCTGG GTAGGAGAAC TAAGGCGCTA ATCGAGAAAC TTAACACAGC CGCCTGCACC 1080 1081 TACCGCATCT CCGTGCAGTG CGTCACGAGC CGGGGTAACT CGGACGAGCT GCAATGCACA 1140 1141 CTGCTGGTGG GCAAGGATGT GGTGGTGGCA CCATCCCAGC TGCGTGTGGA CAACATCACA 1200 1201 CAGATCTCCG CCCAGCTCTC GTGGCTGCCG ACCAACAGTA ACTACAGCCA TATCATCTTC 1260 1261 CTCAATGAAG AGGAATTGGA CATCGTGAAG GCAGCCAGGT ACAAGTATCA ATTCTTCAAC 1320 1321 CTCAGGCCTA ATATGGCCTA CAAGGTGAAG GTCTTGGCCC AGCCACACCA GATGCCCTGG 1380 1381 CAGCTGCCGC TGGAGCAGAG AGAAAAGAAG GAGGCCTGTG TGGAGTTCTC CACGCTGCCT 1440 1441 GCAGGCCCTC CGGCCCCGCC ACAAGACGTC ACCGTCCAAG CTGGGGCCAC CACTGCCTCC 1500 1501 GTTCAGGTCT CCTGGAAGCC CCCTGCACTG ACTCCCACTG GGTTGTCCAA TGGAGCAAAT 1560 1561 GTCACAGGAT ATGGCGTGTA CGCCAAAGGG CAGAGGGTGG CTGAAGTCAT CGCCCCCACA 1620 1621 GCAGATGGCG CGGCAGTGGA GCTGGTCCGG CTGCGCAGCC TGGAGGCCAA GGCCGTGAGT 1680 1681 GTGCGCACCC TGTCCGCACA GGGAGAGTCC ATGGATTCTG CCCTCGCTGC CATCCCCCCT 1740 1741 GACCTCCTGG TGCCTCCAGC CCCCCACCCG AGGACTGCTC CCCCACCAAA GCCATTAGCA 1800 1801 AGTGACATGG ATACCAAAGA CCTGGGTCCC CACGTCAAAG TGGATGAGTC CTGGGAGCAG 1860 1861 AGCCGGCCAC CGGGCCCTGC TCATGGCCAC ATGTTGGAAC CACCTGACAT GCATAGCACT 1920 1921 GGCCCTGGCA GAAGGTCACC CTCGCCCAGC CGGATCCTTC CTCAGCCACA AGGAGCCCCT 1980 1981 GTGTCAACCA CCGTCGCCAA GGCCATGGCC CGTGAAGCTG CACAGAGGGT AGCTGAGAGC 2040 2041 AACAGGTTAG AGAAAAGGAG CCTCTTTTTA GAGCAAAGCA GTGCTGGGCC GTACGCCAAC 2100 2101 TCAGACGAGG AGGATGGCTA TGCCTCCCCT GAGGTCAAGA GGAGAGGCAC ATCGGTGGAT 2160 2161 GACTTCCTGA AAGGGTCAGA GCTGGGCCAG CAGCCTCACT GTTGCCATGG AGATGAGTAC 2220 2221 CACACAGAGA GCAGCCGGGG GTCAGACCTG TCGGACATCA TGGAGGAAGA TGAGGAGGAG 2280 2281 CTATACTCAG AGATGCAGCT GGAGGATGGG GGCCGGCGTC GGCCCAGCGG TACCTCTCAC 2340 2341 AACGCCCTCA AGATTTTAGG AAACTCCGCC TTGATGGGAC GAGGAGACCG GATGGAGCAT 2400 2401 GTGAGCCGAA GGTATTCGCA CAGCGGCGGA GGTCCTCAGA GACATAGGCC GATGGCTCCA 2460 2461 TCCATTGATG AATACACGGG GCGAGACCAT CTTTCTCCAG ACTTCTATGA CGAGTCAGAA 2520 2521 ACGGACCCCG GTGCTGAGGA GCTCCCGGCC CGCATCTTCG TTGCTCTGTT TGACTATGAC 2580 2581 CCGCTCACCA TGTCCCCAAA CCCGGATGCT GCCGAAGAGG AGCTGCCCTT CAAAGAAGGA 2640 2641 CAGATCATCA AGGTATATGG AGACAAAGAC GCAGATGGCT TCTACCGTGG GGAGACCTGT 2700 2701 GCCAGGCTCG GCCTCATTCC CTGTAACATG GTCTCCGAGA TCCATGCGGA TGATGAGGAG 2760 2761 ATGATGGACC AGCTGCTGAG ACAAGGCTTC CTCCCTCTGA ACACACCCGT GGAGAAAATA 2820 2821 GAGAGAAGTA GAAGAAGCGG CCGGGGTCAC TCTGTACCCA CACGGAGAAT GGTGGCTCTC 2880 2881 TACGACTATG ACCCTCGGGA AAGCTCCCCT AACGTGGACG TTGAGGCTGA ACTTCTGTTT 2940 2941 TGCACAGGAG ACATTATTAC TGTTTTTGGT GAAATCGATG AAGACGGGTT TTATTACGGA 3000 3001 GAGCTGAATG GGCAGAAAGG CCTCGTGCCT TCCAATTTCC TGGAAGAAGT GCCTGATGAC 3060 3061 GTGGAGGTCC ACCTTTCCGA TGCTCCGCCC CACTACTCCC ACGACCCGCC CATGCGCACC 3120 3121 AAGGCCAAAA GGAAGAAGAG TGTTCATTTC ACACCCTAA 3159 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cell junction | |
Cellular Component | Plasma membrane | |
Cellular Component | Synapse | |
Biological Process | Negative regulation of phosphatase activity | |
Biological Process | Neuromuscular synaptic transmission |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| CORUM | ||||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | TISSUES | |||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a064 | Homo sapiens | 0.0 | 1926 | undefined |
| LLPS-Mum-a066 | Mus musculus | 0.0 | 1386 | undefined |