LLPS-Ran-4849
Fscb
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Fibrous sheath CABYR-binding protein |
| Gene Name: | Fscb |
| Ensembl Gene: | ENSRNOG00000032241.4 |
| Ensembl Protein: | ENSRNOP00000051161.3 |
| Organism: | Rattus norvegicus |
| Taxa ID: | 10116 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| May be involved in the later stages of fibrous sheath biogenesis. Binds calcium (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSRNOT00000046828.4 | ENSRNOP00000051161.3 |
| UniProt | Q4V7A4, FSCB_RAT | |
| GeneBank | AABR03049340, BC098054 | , AAH98054.1 |
| RefSeq | NM_001271107.1 | NP_001258036.1 |
| Entrez | 500659 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MEESDEPEQP ISLGRQEYRR RRLPSQPMVD KSQQTEIGEK KKGMAAVQPP APKATHSIGN 60 61 IPGGKANYSG KEYESLILSS QLQQTWMKRK QGQEMTDKSF QTDTSVEEKV EVIFMDKALE 120 121 ENSASVGEIA PASPQGVSEV EIPTSRPPSL LIDRAQQTSC TGDWSLISIC SKDKVDKEQQ 180 181 TYFSELETTV KSMPGSSLIK SKEETVPIAE DGSLVEIDGS LEIEVLSTEK IPDVVMSFTE 240 241 GEISGELQAV PDDEATVKAE HFFTEETSIQ APSLAKETSA AETTAKTPKE FVDIQALPAD 300 301 ELSSTEPPAD IRPPLVKGTL SEEPSDQQYP KGTVVAPSEL PVEDLVPLSE EVLEKVQALA 360 361 IDTILDDSGR AESTTVEEAT GEVQPPLSEE ITKEVPAEVH LPIATHSKEI VIIIDKEFAI 420 421 DEDFEDQPPF ITEVAEDEAT AEVQPPSAED APEEVAPSEV LPPPTEQGTV EHMTAEVLSP 480 481 STEVGPAEVP PLPTEEWPLP PVTEESPAEV TPPETEEGPI EPAEEGPEDG LLLPTEEIPS 540 541 EVQPPSLEKV PLEEVVIPQA EEVPLDDLPI EVQPLPAENI AGWVPDEFQA FPVDEYPARE 600 601 DTVEVQPSSL ESAPIEESSV EAQLLAAEAD TAEIEETPTE VAPAEDQLLP AEEVVLKVEV 660 661 ATAWSPLSEL PPAEEATVEA QLTSVEESLK RTSVDVQPPP LDTLAEESPA VKQPLKTDVV 720 721 PMPEFPGEEM TAQDPLPPSV KTTVDQDLLK EHQLPEIADI SQVKLEYTTF TGDKKSKGTD 780 781 SVPEDVTGIK DDQISTFKIE GTIKIELKNS TS 812 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGAAGAAA GTGATGAACC TGAGCAGCCT ATATCGTTAG GAAGGCAGGA ATATAGAAGG 60 61 AGAAGACTAC CCAGCCAACC AATGGTAGAT AAGTCCCAGC AGACTGAAAT AGGAGAAAAA 120 121 AAGAAAGGTA TGGCTGCAGT ACAACCCCCT GCCCCTAAAG CTACCCATAG TATTGGTAAT 180 181 ATTCCTGGAG GTAAGGCCAA CTACTCTGGA AAAGAATATG AGTCTCTTAT ACTGTCCTCT 240 241 CAACTTCAGC AAACTTGGAT GAAGAGAAAG CAAGGCCAGG AAATGACTGA CAAATCTTTT 300 301 CAGACAGACA CCTCTGTGGA AGAAAAAGTG GAAGTCATAT TCATGGATAA AGCACTTGAA 360 361 GAAAACTCAG CTAGTGTTGG AGAAATAGCT CCTGCATCGC CACAGGGTGT TTCAGAAGTA 420 421 GAGATTCCAA CAAGCAGACC CCCCAGTCTT TTAATAGACA GAGCTCAGCA GACCAGCTGT 480 481 ACTGGTGACT GGAGCCTGAT AAGCATTTGC TCAAAAGATA AAGTGGACAA AGAACAACAG 540 541 ACCTACTTCA GTGAGTTAGA AACTACTGTC AAGTCTATGC CAGGTAGCTC CCTGATTAAG 600 601 TCAAAGGAAG AAACAGTACC TATTGCAGAA GATGGTTCTT TGGTGGAAAT AGATGGTTCT 660 661 CTCGAAATAG AGGTTCTGTC AACTGAAAAA ATCCCCGATG TAGTGATGTC TTTTACTGAA 720 721 GGGGAGATTT CTGGTGAATT ACAGGCTGTA CCAGATGATG AGGCCACAGT TAAAGCAGAA 780 781 CATTTCTTTA CAGAGGAGAC CTCTATTCAA GCACCATCTC TAGCTAAAGA GACCTCTGCA 840 841 GCTGAGACAA CCGCTAAAAC CCCAAAAGAA TTTGTGGACA TACAGGCTTT ACCAGCTGAT 900 901 GAGCTTTCTT CTACAGAGCC TCCTGCTGAC ATTCGTCCTC CATTAGTGAA AGGGACTCTT 960 961 TCAGAGGAGC CTTCTGATCA ACAGTATCCC AAAGGAACTG TGGTGGCTCC TTCAGAACTT 1020 1021 CCTGTTGAAG ATCTGGTTCC ACTCTCAGAA GAGGTGCTTG AGAAAGTTCA AGCTTTAGCA 1080 1081 ATTGACACTA TCCTTGATGA CTCAGGCAGA GCAGAGTCTA CTACTGTTGA AGAGGCTACT 1140 1141 GGTGAAGTCC AACCTCCTCT GTCTGAAGAG ATTACTAAAG AAGTACCTGC TGAAGTTCAT 1200 1201 TTACCAATAG CTACACACTC TAAAGAAATT GTTATTATAA TAGATAAGGA ATTTGCTATT 1260 1261 GATGAGGACT TTGAAGATCA GCCTCCATTC ATTACAGAAG TTGCTGAAGA TGAGGCTACT 1320 1321 GCAGAAGTTC AGCCTCCATC AGCAGAGGAT GCTCCTGAAG AAGTGGCTCC TTCAGAAGTT 1380 1381 CTACCTCCAC CTACTGAACA GGGCACTGTA GAACACATGA CTGCAGAAGT TCTATCTCCA 1440 1441 TCAACTGAAG TGGGCCCTGC AGAAGTTCCA CCTCTACCAA CTGAGGAGTG GCCTCTACCT 1500 1501 CCAGTAACTG AGGAGAGCCC TGCAGAAGTT ACACCTCCAG AAACAGAGGA GGGCCCTATA 1560 1561 GAACCAGCTG AGGAGGGCCC TGAAGATGGC CTACTTTTAC CAACTGAGGA GATCCCTTCA 1620 1621 GAAGTTCAGC CTCCATCCCT TGAGAAGGTT CCTCTAGAAG AAGTAGTGAT TCCACAAGCT 1680 1681 GAGGAAGTTC CTCTAGATGA TTTACCCATT GAAGTGCAAC CTTTGCCAGC TGAGAACATT 1740 1741 GCAGGATGGG TCCCAGATGA ATTTCAGGCT TTTCCAGTTG ATGAATACCC TGCAAGAGAG 1800 1801 GACACTGTTG AAGTCCAGCC TTCCTCATTA GAGAGTGCTC CAATAGAAGA AAGCTCTGTT 1860 1861 GAAGCTCAGC TTCTAGCAGC TGAGGCAGAT ACTGCAGAAA TTGAAGAGAC TCCTACAGAA 1920 1921 GTGGCACCAG CTGAAGATCA GCTTCTACCA GCTGAGGAAG TGGTCCTAAA AGTAGAAGTT 1980 1981 GCTACAGCTT GGTCTCCCTT ATCTGAGTTG CCTCCTGCAG AAGAAGCCAC TGTGGAAGCC 2040 2041 CAACTGACAT CGGTTGAAGA GAGCTTGAAA AGAACTTCTG TTGATGTTCA GCCTCCACCA 2100 2101 CTTGACACCC TTGCAGAAGA GTCTCCTGCT GTCAAACAGC CTTTAAAAAC TGATGTGGTT 2160 2161 CCTATGCCAG AGTTTCCTGG GGAAGAGATG ACTGCTCAAG ATCCACTTCC ACCTTCAGTA 2220 2221 AAAACCACCG TAGATCAGGA TCTACTAAAA GAACATCAAT TGCCCGAGAT AGCAGACATC 2280 2281 TCACAAGTAA AATTGGAGTA TACTACTTTC ACAGGTGATA AAAAGTCTAA AGGAACAGAT 2340 2341 TCTGTTCCTG AAGATGTAAC TGGGATCAAG GACGATCAGA TCTCCACTTT CAAAATAGAA 2400 2401 GGTACCATTA AAATAGAGTT AAAGAACTCC ACTTCCTAA 2439 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Motile cilium | |
Biological Process | Negative regulation of protein sumoylation |
▼ ANNOTATION
| Domain | ||||
| LCR-eXXXplorer | CDD | |||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| TISSUES | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Mum-4230 | Mus musculus | 73.49 | 0.0 | 608 |
| LLPS-Orc-3740 | Oryctolagus cuniculus | 61.54 | 3e-12 | 74.3 |
| LLPS-Loa-1407 | Loxodonta africana | 59.72 | 3e-63 | 234 |
| LLPS-Mal-3327 | Mandrillus leucophaeus | 58.66 | 1e-48 | 188 |
| LLPS-Paa-3453 | Papio anubis | 57.54 | 4e-47 | 183 |
| LLPS-Mam-1591 | Macaca mulatta | 57.54 | 1e-46 | 183 |
| LLPS-Man-4464 | Macaca nemestrina | 57.54 | 8e-47 | 183 |
| LLPS-Maf-3595 | Macaca fascicularis | 56.98 | 2e-46 | 181 |
| LLPS-Bot-4879 | Bos taurus | 55.34 | 1e-55 | 209 |
| LLPS-Sus-3629 | Sus scrofa | 54.27 | 7e-50 | 191 |
| LLPS-Gog-4697 | Gorilla gorilla | 53.16 | 9e-47 | 181 |
| LLPS-Ova-4130 | Ovis aries | 51.96 | 3e-39 | 160 |
| LLPS-Ere-0377 | Erinaceus europaeus | 48.09 | 4e-31 | 135 |
| LLPS-Sah-0627 | Sarcophilus harrisii | 46.06 | 1e-27 | 122 |
| LLPS-Eqc-1306 | Equus caballus | 42.2 | 5e-62 | 228 |
| LLPS-Aim-3173 | Ailuropoda melanoleuca | 40.73 | 8e-47 | 180 |
| LLPS-Rhb-0486 | Rhinopithecus bieti | 40.0 | 2e-51 | 197 |
| LLPS-Poa-1817 | Pongo abelii | 38.66 | 9e-54 | 204 |
| LLPS-Cea-2696 | Cercocebus atys | 37.88 | 3e-48 | 187 |
| LLPS-Pap-2128 | Pan paniscus | 37.33 | 1e-50 | 192 |
| LLPS-Caf-4502 | Canis familiaris | 36.24 | 7e-73 | 260 |
| LLPS-Hos-2815 | Homo sapiens | 34.17 | 1e-54 | 206 |
| LLPS-Cas-1991 | Carlito syrichta | 32.76 | 2e-53 | 201 |
| LLPS-Myl-1050 | Myotis lucifugus | 29.72 | 3e-27 | 122 |