LLPS-Ran-3871
Cbx2

▼ OVERVIEW

Status: Unreviewed
Protein Name: Chromobox 2
Gene Name: Cbx2, LOC303730, rCG_34544
Ensembl Gene: ENSRNOG00000049215.1
Ensembl Protein: ENSRNOP00000067878.1
Organism: Rattus norvegicus
Taxa ID: 10116
LLPS Type: Scaffold


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Chromatin, Nuclear speckle, PcG bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEELSSVGEQ  VFAAECILSK  RLRKGKLEYL  VKWRGWSSKH  NSWEPEENIL  DPRLLLAFQK  60
61    KEHEKEVQNR  KRGKRPRGRP  RKHTVMSSCS  RRSKLKEPDA  PSKSKSSSSS  SSSTSSSSSS  120
121   DEEEEDDDDS  DLDSKRGSRG  RETHPVPQKK  AQILVAKPEL  KDPIRKKRGR  KPLPPEQKAA  180
181   RRPVSLAKVL  KTTRKDLVTS  APKLPPPLSA  PVAGLAALKA  HTKEACGGPS  TMATPENLAS  240
241   LMKGMAGSPS  RGGISWQSSI  VHYMNRMSQS  QAQAASRLAL  KAQAANKCSL  GPDLKVRTQK  300
301   GELGVNPAGS  KVPKAPGSVA  AEQQRGNNSG  SPGSQLPPTQ  ELSLQVLDLQ  SVKNGVPGVG  360
361   LPARHATATK  AIPATNTATG  KGPGSGPTGV  NVTNAPTDTS  KGEKLTCKTA  ALPAPSVKRD  420
421   AAKSIAASGG  QEGHTVPGEG  QKPPALCELS  TGEENSSSDS  DPDSSSLPSA  GQNLSVAVQT  480
481   SQDWKPTRSL  IEHVFVTDVT  ANLITVTVKE  SPTSVGFFNL  KHY  523
Nucleotide CDS Sequence (FASTA)
1     ATGGAGGAGC  TGAGCAGCGT  GGGCGAGCAG  GTCTTCGCCG  CCGAGTGCAT  CCTGAGCAAG  60
61    AGGCTCCGCA  AGGGCAAGCT  GGAGTACCTG  GTCAAGTGGC  GCGGCTGGTC  CTCCAAACAC  120
121   AACAGCTGGG  AGCCCGAAGA  GAACATCTTG  GACCCGAGGC  TGCTCCTGGC  CTTCCAGAAG  180
181   AAGGAACATG  AGAAGGAGGT  GCAGAACCGG  AAAAGAGGCA  AGAGGCCCAG  GGGCAGGCCA  240
241   AGGAAGCACA  CAGTCATGTC  CTCCTGCAGC  CGGCGCTCCA  AGCTCAAGGA  ACCAGATGCA  300
301   CCGTCCAAGT  CCAAATCCAG  CAGTTCATCC  TCTTCCTCCA  CATCTTCCTC  CTCTTCCTCA  360
361   GATGAAGAAG  AAGAAGACGA  CGACGACAGT  GACCTGGACT  CCAAGAGGGG  ATCCCGGGGC  420
421   CGTGAAACCC  ACCCGGTCCC  TCAGAAAAAA  GCCCAGATCC  TGGTAGCCAA  GCCAGAGCTG  480
481   AAGGATCCCA  TCCGAAAGAA  GCGCGGACGC  AAGCCTCTAC  CCCCGGAACA  GAAGGCAGCT  540
541   CGGAGACCGG  TAAGCCTGGC  CAAGGTGCTA  AAGACCACCA  GGAAGGACCT  GGTGACCTCA  600
601   GCCCCCAAGC  TGCCCCCTCC  ACTCAGTGCT  CCTGTGGCAG  GCCTGGCTGC  CTTGAAAGCC  660
661   CACACCAAAG  AGGCCTGTGG  CGGCCCCAGC  ACTATGGCAA  CCCCAGAGAA  CCTGGCCAGT  720
721   CTGATGAAAG  GCATGGCCGG  GAGCCCCAGC  CGAGGCGGCA  TCAGCTGGCA  GAGTTCTATC  780
781   GTACACTACA  TGAACCGCAT  GAGCCAGAGT  CAGGCTCAGG  CCGCCAGCCG  GCTGGCGCTC  840
841   AAGGCCCAGG  CTGCCAACAA  GTGCAGCCTC  GGGCCGGACC  TGAAAGTGCG  GACGCAGAAA  900
901   GGGGAGCTAG  GGGTGAACCC  CGCAGGAAGC  AAGGTTCCCA  AGGCCCCTGG  CAGTGTTGCT  960
961   GCAGAGCAGC  AGAGAGGGAA  TAATTCGGGG  AGTCCAGGTT  CCCAGCTGCC  ACCCACTCAG  1020
1021  GAGTTGAGCC  TTCAGGTCCT  TGACTTACAG  AGCGTCAAGA  ACGGTGTGCC  CGGTGTGGGC  1080
1081  CTGCCTGCTC  GCCATGCCAC  AGCCACCAAG  GCTATTCCTG  CCACCAACAC  AGCCACGGGG  1140
1141  AAAGGTCCTG  GGAGCGGCCC  CACAGGAGTA  AACGTGACCA  ACGCTCCCAC  AGACACCAGC  1200
1201  AAAGGGGAAA  AACTGACTTG  CAAGACAGCG  GCTCTGCCTG  CCCCTTCTGT  CAAGAGGGAC  1260
1261  GCCGCTAAAA  GCATTGCTGC  CTCTGGTGGG  CAGGAGGGCC  ACACAGTCCC  CGGAGAAGGT  1320
1321  CAGAAGCCAC  CTGCACTGTG  TGAACTGAGC  ACAGGAGAGG  AGAACAGCAG  TTCTGACTCA  1380
1381  GACCCCGACT  CATCCTCGCT  GCCTAGTGCT  GGGCAGAACC  TGTCGGTAGC  TGTCCAGACC  1440
1441  AGCCAGGACT  GGAAACCTAC  CCGAAGTCTC  ATCGAGCACG  TCTTCGTCAC  GGATGTCACA  1500
1501  GCCAACCTCA  TCACTGTCAC  CGTGAAGGAG  TCCCCCACCA  GTGTGGGCTT  CTTCAACTTG  1560
1561  AAGCATTATT  GA  1572

▼ ANNOTATION

Disorder
IUPred2A
Interaction
RAINIIDMIST
Physicochemical
Compute pI/MwAAindex
Localization
COMPARTMENTS
Expression
TISSUES

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ora-1139Ornithorhynchus anatinus90.162e-27 116
LLPS-Mum-0999Mus musculus90.080.0 757
LLPS-Leo-0570Lepisosteus oculatus88.062e-33 137
LLPS-Tar-0377Takifugu rubripes86.578e-33 134
LLPS-Scf-0659Scleropages formosus86.572e-32 134
LLPS-Icp-3881Ictalurus punctatus85.071e-31 131
LLPS-Ten-2688Tetraodon nigroviridis85.071e-31 130
LLPS-Orn-3610Oreochromis niloticus85.074e-32 132
LLPS-Scm-0689Scophthalmus maximus85.071e-31 131
LLPS-Xim-2416Xiphophorus maculatus84.487e-26 114
LLPS-Orl-1477Oryzias latipes84.489e-26 114
LLPS-Pof-3367Poecilia formosa84.486e-26 114
LLPS-Gaa-2292Gasterosteus aculeatus83.587e-31 129
LLPS-Dar-3305Danio rerio83.582e-31 130
LLPS-Asm-3540Astyanax mexicanus82.094e-31 130
LLPS-Eqc-0958Equus caballus81.90.0 687
LLPS-Mea-2772Mesocricetus auratus81.840.0 655
LLPS-Sus-0148Sus scrofa81.340.0 656
LLPS-Bot-0507Bos taurus80.410.0 658
LLPS-Fud-2333Fukomys damarensis80.380.0 533
LLPS-Gog-2267Gorilla gorilla80.220.0 658
LLPS-Hos-2579Homo sapiens80.220.0 660
LLPS-Ict-0587Ictidomys tridecemlineatus80.20.0 598
LLPS-Pat-1555Pan troglodytes79.850.0 655
LLPS-Tut-2313Tursiops truncatus79.660.0 658
LLPS-Aon-2323Aotus nancymaae79.10.0 648
LLPS-Otg-3955Otolemur garnettii79.10.0 635
LLPS-Cap-2693Cavia porcellus78.960.0 628
LLPS-Ova-0621Ovis aries78.560.0 573
LLPS-Caj-3072Callithrix jacchus78.360.0 630
LLPS-Nol-0146Nomascus leucogenys77.910.0 571
LLPS-Cas-0319Carlito syrichta77.870.0 548
LLPS-Cea-1690Cercocebus atys77.80.0 650
LLPS-Fec-3246Felis catus77.610.0 642
LLPS-Pap-1671Pan paniscus77.450.0 575
LLPS-Mam-1346Macaca mulatta77.430.0 633
LLPS-Rhb-0802Rhinopithecus bieti77.430.0 645
LLPS-Chs-3647Chlorocebus sabaeus77.240.0 643
LLPS-Loa-1963Loxodonta africana75.955e-177 515
LLPS-Mal-2204Mandrillus leucophaeus75.70.0 565
LLPS-Myl-1388Myotis lucifugus75.50.0 526
LLPS-Dio-1080Dipodomys ordii74.810.0 558
LLPS-Maf-3875Macaca fascicularis73.980.0 618
LLPS-Man-0055Macaca nemestrina73.980.0 619
LLPS-Orc-1861Oryctolagus cuniculus73.437e-165 483
LLPS-Mup-3576Mustela putorius furo73.350.0 534
LLPS-Aim-0487Ailuropoda melanoleuca73.152e-177 515
LLPS-Caf-3664Canis familiaris73.052e-164 481
LLPS-Paa-3753Papio anubis73.030.0 572
LLPS-Lac-1652Latimeria chalumnae69.642e-2097.1
LLPS-Xet-2746Xenopus tropicalis69.232e-24 108
LLPS-Gaga-1542Gallus gallus67.691e-22 105
LLPS-Mod-3586Monodelphis domestica67.10.0 543
LLPS-Poa-1303Pongo abelii66.152e-23 104
LLPS-Sah-1714Sarcophilus harrisii66.02e-155 460
LLPS-Fia-1156Ficedula albicollis65.852e-1169.7
LLPS-Urm-4004Ursus maritimus65.851e-1170.5
LLPS-Anc-0933Anolis carolinensis65.621e-2095.9
LLPS-Pes-1179Pelodiscus sinensis65.03e-2094.7
LLPS-Anp-0790Anas platyrhynchos64.448e-1269.3
LLPS-Tag-1733Taeniopygia guttata63.642e-1272.8
LLPS-Drm-0148Drosophila melanogaster54.03e-1272.8
LLPS-Cae-0886Caenorhabditis elegans49.092e-1168.9
LLPS-Phv-2032Phaseolus vulgaris49.092e-0963.5