LLPS-Ran-3375
Srpk1

▼ OVERVIEW

Status: Unreviewed
Protein Name: SRSF protein kinase 1
Gene Name: Srpk1
Ensembl Gene: ENSRNOG00000000511.8
Ensembl Protein: ENSRNOP00000075811.1
Organism: Rattus norvegicus
Taxa ID: 10116
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MERKVLALQA  RKKRTKAKKD  KAQRKPETQH  RGSAPHSESD  IPEQEEEILG  SDDDEQEDPN  60
61    DYCKGGYHLV  KIGDLFNGRY  HVIRKLGWGH  FSTVWLSWDI  QGKKFVAMKV  VKSAEHYTET  120
121   ALDEIRLLKS  VRNSDPNDPN  GEMVVQLLDD  FKISGVNGTH  ICMVFEVLGH  HLLKWIIKSN  180
181   YQGLPLPCVK  KIIQQVLQGL  DYLHTKCRII  HTDIKPENIL  LSVNEQYIRR  LAAEATEWQR  240
241   SGAPPPSGSA  VSTAPQPKPA  DKMSKNKKKK  LKKKQKRQAE  LLEKRMQEIE  EMEKESGPGQ  300
301   KRPNKQEESE  SPVERPLTEN  PPNKMTQEKL  EESSSIGQDQ  TLTEHGGEGG  APEINCNGVI  360
361   GIVNYTANSN  NETLRLKEDL  HNANDCDGRT  LKQEPSFLSS  PNGDSSPSPE  TDSCTPSGSE  420
421   VPETMACQAS  VERSLTLTQQ  DITHLQERIR  AHTPSGDEQE  REHNGALDSK  GKFSAGNFLL  480
481   NPLEPKNAEK  LKVNVCDVGE  ACGMHKHFTE  DIQTRQYRSL  EVLIGSGYNT  PADIWSTACM  540
541   AFELATGDYL  FEPHSGEDYT  RDEDHIALII  ELLGKVPRKL  IVAGKYSKEF  FTKKGDLKHI  600
601   TKLKPWGLLE  VLVEKYEWPQ  EEAAGFTDFL  LPMLELMPEK  RATAAECLRH  PWLNS  655
Nucleotide CDS Sequence (FASTA)
1     ATGGAGCGGA  AAGTGCTCGC  GCTCCAGGCC  CGAAAGAAAA  GGACCAAGGC  CAAGAAGGAC  60
61    AAAGCCCAAA  GGAAGCCTGA  AACCCAGCAC  CGAGGCTCTG  CACCCCACTC  CGAGAGCGAC  120
121   ATCCCCGAGC  AGGAGGAGGA  GATTCTGGGG  TCTGATGATG  ATGAACAGGA  AGACCCTAAC  180
181   GACTACTGTA  AAGGAGGTTA  TCATCTTGTG  AAAATTGGAG  ATCTATTTAA  CGGGCGATAC  240
241   CATGTGATTC  GAAAATTAGG  CTGGGGACAC  TTTTCCACAG  TATGGTTATC  ATGGGATATT  300
301   CAGGGAAAGA  AGTTTGTAGC  AATGAAAGTA  GTTAAAAGTG  CCGAACATTA  CACAGAGACA  360
361   GCACTGGATG  AGATCCGGCT  CCTGAAATCG  GTTCGCAATT  CAGACCCGAA  TGATCCAAAT  420
421   GGAGAAATGG  TCGTTCAACT  ACTAGATGAC  TTTAAAATAT  CAGGCGTTAA  TGGAACACAT  480
481   ATCTGCATGG  TGTTTGAAGT  TTTAGGACAT  CATCTACTCA  AGTGGATCAT  CAAGTCCAAC  540
541   TATCAGGGGC  TTCCGCTGCC  TTGTGTCAAA  AAAATTATTC  AGCAAGTGCT  CCAGGGTCTG  600
601   GATTACTTAC  ACACCAAGTG  CCGGATCATC  CACACTGACA  TCAAGCCGGA  AAACATCCTG  660
661   TTGTCCGTGA  ACGAGCAGTA  CATTCGGAGG  CTGGCTGCAG  AGGCCACAGA  GTGGCAACGG  720
721   TCTGGAGCTC  CCCCACCATC  GGGGTCTGCA  GTCAGCACTG  CTCCACAGCC  TAAGCCAGCT  780
781   GACAAAATGT  CAAAGAATAA  GAAGAAGAAA  TTGAAGAAGA  AGCAGAAGCG  CCAGGCAGAA  840
841   TTACTAGAGA  AGCGAATGCA  GGAAATTGAG  GAAATGGAGA  AAGAGTCGGG  CCCTGGGCAA  900
901   AAAAGACCTA  ACAAGCAAGA  AGAATCAGAG  AGTCCTGTTG  AAAGACCCTT  GACAGAGAAC  960
961   CCACCTAATA  AAATGACCCA  AGAGAAACTT  GAAGAGTCGA  GTTCCATTGG  CCAGGATCAG  1020
1021  ACACTCACGG  AGCATGGTGG  AGAGGGTGGT  GCGCCAGAAA  TTAATTGCAA  TGGAGTGATT  1080
1081  GGAATCGTTA  ATTACACTGC  AAACAGTAAC  AATGAAACCT  TGAGGCTTAA  AGAGGACCTA  1140
1141  CATAATGCCA  ATGACTGTGA  TGGCCGCACT  CTGAAGCAGG  AACCTAGCTT  CCTAAGCTCT  1200
1201  CCAAATGGAG  ACAGTAGTCC  GTCTCCAGAA  ACAGACTCTT  GCACACCTTC  GGGCTCGGAG  1260
1261  GTGCCCGAGA  CCATGGCGTG  CCAGGCCTCT  GTAGAGCGGT  CACTCACCCT  CACCCAACAG  1320
1321  GACATCACCC  ACCTGCAGGA  GCGCATCCGG  GCACATACGC  CTTCTGGGGA  TGAGCAGGAG  1380
1381  CGGGAACACA  ATGGAGCGCT  GGACAGCAAA  GGAAAATTCT  CTGCTGGAAA  TTTCTTATTA  1440
1441  AATCCCCTGG  AGCCAAAAAA  TGCAGAAAAG  CTCAAAGTGA  ATGTGTGTGA  CGTAGGTGAG  1500
1501  GCGTGCGGAA  TGCACAAGCA  TTTCACCGAA  GACATCCAGA  CCCGGCAGTA  CCGGTCTTTG  1560
1561  GAGGTCCTGA  TAGGATCTGG  CTACAACACC  CCTGCTGACA  TCTGGAGCAC  AGCATGCATG  1620
1621  GCCTTTGAAC  TAGCCACAGG  GGACTATCTG  TTTGAGCCTC  ATTCGGGGGA  GGATTACACG  1680
1681  CGAGATGAAG  ACCACATCGC  CCTGATCATA  GAGCTCCTGG  GGAAGGTGCC  TCGCAAGCTC  1740
1741  ATTGTAGCAG  GGAAATACTC  CAAGGAATTT  TTCACCAAAA  AAGGTGACCT  GAAACACATC  1800
1801  ACCAAGTTGA  AGCCTTGGGG  TCTTCTGGAG  GTTCTGGTGG  AGAAGTATGA  GTGGCCTCAG  1860
1861  GAGGAGGCTG  CTGGCTTCAC  AGATTTCCTG  CTGCCCATGT  TGGAGCTCAT  GCCTGAGAAG  1920
1921  AGAGCCACTG  CCGCTGAGTG  TCTCCGGCAT  CCTTGGCTGA  ACTCCTAA  1968

▼ ANNOTATION

Disorder
D2P2IUPred2A
PTM
EPSD
Interaction
RAINMIST
Physicochemical
Compute pI/MwAAindex
Function
iEKPD
Localization
COMPARTMENTS
Expression
TISSUES

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mum-3489Mus musculus93.740.01140
LLPS-Sus-0795Sus scrofa90.690.01107
LLPS-Caf-2757Canis familiaris90.530.01102
LLPS-Maf-4027Macaca fascicularis90.230.01102
LLPS-Chs-4484Chlorocebus sabaeus90.170.01090
LLPS-Mam-3941Macaca mulatta90.020.01091
LLPS-Ova-1811Ovis aries89.860.01083
LLPS-Urm-0474Ursus maritimus89.230.0 925
LLPS-Cea-4461Cercocebus atys88.170.01054
LLPS-Rhb-4750Rhinopithecus bieti87.940.01042
LLPS-Ten-0660Tetraodon nigroviridis86.762e-123 383
LLPS-Eqc-2171Equus caballus86.010.01084
LLPS-Cas-0583Carlito syrichta84.582e-116 371
LLPS-Icp-2701Ictalurus punctatus83.642e-129 403
LLPS-Scf-0906Scleropages formosus82.42e-119 380
LLPS-Cii-1858Ciona intestinalis81.681e-107 346
LLPS-Scm-1541Scophthalmus maximus81.63e-114 369
LLPS-Sah-3672Sarcophilus harrisii80.911e-53 196
LLPS-Xet-3546Xenopus tropicalis80.539e-105 338
LLPS-Cap-2189Cavia porcellus79.140.0 943
LLPS-Man-2202Macaca nemestrina78.898e-110 351
LLPS-Paa-3469Papio anubis78.899e-110 351
LLPS-Hos-3546Homo sapiens78.51e-110 354
LLPS-Pat-3353Pan troglodytes78.52e-110 353
LLPS-Pap-1419Pan paniscus78.52e-110 353
LLPS-Gog-3204Gorilla gorilla78.52e-110 353
LLPS-Loa-0352Loxodonta africana77.58e-108 344
LLPS-Tar-0990Takifugu rubripes76.491e-109 356
LLPS-Gaga-3917Gallus gallus76.440.0 910
LLPS-Poa-3885Pongo abelii76.084e-110 350
LLPS-Lac-2361Latimeria chalumnae76.021e-101 329
LLPS-Xim-1153Xiphophorus maculatus75.91e-107 353
LLPS-Pof-0153Poecilia formosa75.73e-108 354
LLPS-Aon-2664Aotus nancymaae75.66e-110 351
LLPS-Ict-2564Ictidomys tridecemlineatus74.885e-110 350
LLPS-Myl-2709Myotis lucifugus74.886e-110 350
LLPS-Bot-4375Bos taurus74.882e-109 349
LLPS-Caj-4694Callithrix jacchus74.646e-109 348
LLPS-Otg-3398Otolemur garnettii74.427e-109 346
LLPS-Fec-2534Felis catus74.427e-109 349
LLPS-Asm-2208Astyanax mexicanus74.313e-106 346
LLPS-Nol-0041Nomascus leucogenys73.943e-78 263
LLPS-Ora-3122Ornithorhynchus anatinus73.766e-108 344
LLPS-Dio-3465Dipodomys ordii73.513e-99 308
LLPS-Mup-4167Mustela putorius furo71.942e-109 347
LLPS-Fud-2611Fukomys damarensis71.434e-109 348
LLPS-Orc-3065Oryctolagus cuniculus70.09e-108 344
LLPS-Orn-1648Oreochromis niloticus68.421e-89 296
LLPS-Meg-1627Meleagris gallopavo67.990.0 742
LLPS-Cae-1614Caenorhabditis elegans66.842e-79 278
LLPS-Mea-3996Mesocricetus auratus66.551e-109 348
LLPS-Orl-3618Oryzias latipes65.96e-77 263
LLPS-Leo-3798Lepisosteus oculatus62.862e-67 238
LLPS-Pot-1802Populus trichocarpa61.311e-58 212
LLPS-Hea-1872Helianthus annuus60.712e-56 206
LLPS-Asn-0815Aspergillus nidulans60.361e-60 218
LLPS-Zem-1070Zea mays60.276e-21 101
LLPS-Viv-2103Vitis vinifera60.124e-56 205
LLPS-Arl-2277Arabidopsis lyrata60.125e-58 210
LLPS-Mel-0834Melampsora laricipopulina60.122e-60 222
LLPS-Dac-1523Daucus carota60.122e-57 209
LLPS-Sol-0754Solanum lycopersicum60.124e-56 205
LLPS-Sot-1508Solanum tuberosum59.772e-55 202
LLPS-Bro-1743Brassica oleracea59.523e-56 204
LLPS-Coc-2034Corchorus capsularis59.522e-55 204
LLPS-Art-1522Arabidopsis thaliana59.522e-56 206
LLPS-Via-2038Vigna angularis59.522e-56 206
LLPS-Thc-0222Theobroma cacao59.524e-55 202
LLPS-Php-2081Physcomitrella patens59.244e-58 212
LLPS-Asc-0290Aspergillus clavatus59.172e-59 215
LLPS-Phv-1665Phaseolus vulgaris58.932e-55 203
LLPS-Gor-0081Gossypium raimondii58.933e-56 205
LLPS-Met-1848Medicago truncatula58.931e-54 201
LLPS-Glm-2038Glycine max58.931e-57 209
LLPS-Sem-2287Selaginella moellendorffii58.792e-62 220
LLPS-Ast-1409Aspergillus terreus58.722e-60 218
LLPS-Nia-1141Nicotiana attenuata58.625e-55 201
LLPS-Asni-0788Aspergillus niger58.581e-58 213
LLPS-Mae-1555Manihot esculenta58.383e-56 205
LLPS-Brn-1776Brassica napus58.386e-55 203
LLPS-Vir-1460Vigna radiata58.332e-56 206
LLPS-Gaa-2797Gasterosteus aculeatus58.070.0 701
LLPS-Cogr-1601Colletotrichum graminicola58.013e-62 221
LLPS-Cog-0792Colletotrichum gloeosporioides58.011e-62 221
LLPS-Tum-0290Tuber melanosporum58.016e-59 214
LLPS-Pytr-0143Pyrenophora triticirepentis57.878e-61 220
LLPS-Lem-1158Leptosphaeria maculans57.874e-60 216
LLPS-Ved-0078Verticillium dahliae57.845e-63 223
LLPS-Brr-0386Brassica rapa57.82e-54 202
LLPS-Mao-1278Magnaporthe oryzae57.463e-61 220
LLPS-Asf-0259Aspergillus flavus57.385e-62 222
LLPS-Aso-0046Aspergillus oryzae57.385e-62 221
LLPS-Trr-1515Trichoderma reesei57.33e-62 221
LLPS-Asfu-0019Aspergillus fumigatus57.228e-60 216
LLPS-Nef-0764Neosartorya fischeri57.229e-60 216
LLPS-Cym-1088Cyanidioschyzon merolae57.062e-55 207
LLPS-Fuo-1531Fusarium oxysporum56.911e-61 220
LLPS-Fuv-0382Fusarium verticillioides56.911e-61 220
LLPS-Cus-1426Cucumis sativus56.764e-58 211
LLPS-Scs-1073Sclerotinia sclerotiorum56.762e-62 223
LLPS-Usm-1548Ustilago maydis56.651e-57 213
LLPS-Spr-0503Sporisorium reilianum56.652e-57 213
LLPS-Pug-0141Puccinia graminis55.312e-54 201
LLPS-Zyt-0421Zymoseptoria tritici55.149e-59 213
LLPS-Chc-0552Chondrus crispus54.942e-51 193
LLPS-Dos-1409Dothistroma septosporum54.552e-58 213
LLPS-Miv-0890Microbotryum violaceum54.087e-58 213
LLPS-Abg-1946Absidia glauca54.072e-52 193
LLPS-Crn-1464Cryptococcus neoformans53.771e-57 211
LLPS-Blg-1448Blumeria graminis53.662e-60 218
LLPS-Drm-1634Drosophila melanogaster51.67e-52 196
LLPS-Scj-1348Schizosaccharomyces japonicus44.581e-41 161
LLPS-Pes-0123Pelodiscus sinensis40.563e-23 108
LLPS-Anp-0109Anas platyrhynchos40.563e-23 108
LLPS-Ere-0389Erinaceus europaeus40.569e-23 106
LLPS-Mal-0936Mandrillus leucophaeus40.561e-22 106
LLPS-Tut-0276Tursiops truncatus40.569e-23 107
LLPS-Amt-2146Amborella trichopoda36.751e-23 107
LLPS-Tag-1868Taeniopygia guttata36.639e-23 106
LLPS-Fia-1716Ficedula albicollis36.636e-23 107
LLPS-Orm-1866Oryza meridionalis36.142e-23 107
LLPS-Sob-0296Sorghum bicolor36.142e-24 110
LLPS-Orp-0988Oryza punctata36.142e-23 107
LLPS-Lep-1960Leersia perrieri36.142e-24 110
LLPS-Orb-0988Oryza barthii36.144e-23 106
LLPS-Brd-1521Brachypodium distachyon35.583e-23 107
LLPS-Org-0398Oryza glaberrima35.333e-23 107
LLPS-Ors-0685Oryza sativa35.333e-23 107
LLPS-Ori-1295Oryza indica35.333e-23 107
LLPS-Tra-1266Triticum aestivum34.947e-23 105
LLPS-Hov-0596Hordeum vulgare33.512e-22 104
LLPS-Chr-0893Chlamydomonas reinhardtii33.339e-23 107
LLPS-Prp-1307Prunus persica32.961e-22 105