LLPS-Ran-2888
Trim25

▼ OVERVIEW

Status: Unreviewed
Protein Name: Tripartite motif-containing 25
Gene Name: Trim25
Ensembl Gene: ENSRNOG00000002341.7
Ensembl Protein: ENSRNOP00000052533.4
Organism: Rattus norvegicus
Taxa ID: 10116
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, PML nuclear body, Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSRNOT00000055674.4ENSRNOP00000052533.4
UniProtD4A9N5, D4A9N5_RAT
GeneBankAC119015
Entrez494338

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAELFPLAEE  LSCSICLEPF  KEPVTTPCGH  NFCRSCLNET  WVVQGPPYRC  PQCRTVYQVR  60
61    PQLHKNTVLC  AVVEQFLQAE  QARTPVDDWI  PPTRSAASSS  DTQVSCDHCL  KEVAVKTCLV  120
121   CMASFCQEHL  RPHIDSPAFQ  DHPLQPPVRD  LLRRKCSRHN  RLREMFCPEH  GECICHICLV  180
181   EHKTCSPTIL  SQASADLENK  LRQKLTIMYS  HINGASKALE  DVKSKQQNVQ  ESMKRKMLQL  240
241   RQEYLEMKAV  IDAAETSSTH  KLKEEEKRVY  GKLDTIYQVL  LKKKNEMQNL  KAEVELILAK  300
301   GDEFEFLEKA  AKLQEVSTKP  VYIPKIDLDH  DLIKGVYQGA  LDLKSELKLS  LKQLQEKKAE  360
361   EPCNSGNVGD  HAQSTSKPTR  PAKKTAPDKK  TKKTPGAAGA  AGAAGAAGAA  GPTSYSSSSN  420
421   KLPTFGAPGQ  ATIPDATLKP  NAPQPNSAAV  KAKVLENFLT  MSRTELLEYF  VKVVFDYNTA  480
481   HNKVALADNY  TTASVADGLQ  HYRSHPQRFT  YCSQVLGLHC  YKKGIHYWEV  ELQKNNFCGV  540
541   GVCYGSMDRQ  GPESRLGRNP  SSWCVEWFNN  KISAWHNNVE  KTLPSTKATR  VGVLLNCDHG  600
601   FVIFFAVTEK  VYLMYKFKVD  FTEALYPAFW  VFSAGTTLSI  CSK  643
Nucleotide CDS Sequence (FASTA)
1     ATGGCCGAGC  TGTTTCCTCT  GGCCGAGGAG  CTGTCGTGCT  CCATCTGCCT  GGAGCCCTTC  60
61    AAGGAGCCCG  TCACCACCCC  GTGCGGCCAC  AATTTCTGCA  GGTCATGCCT  AAATGAGACG  120
121   TGGGTCGTCC  AGGGCCCGCC  GTACCGGTGC  CCGCAGTGTC  GCACCGTGTA  CCAGGTGCGC  180
181   CCGCAGCTGC  ACAAGAACAC  GGTGCTGTGC  GCAGTGGTCG  AGCAGTTTCT  TCAGGCCGAG  240
241   CAGGCGCGGA  CCCCCGTGGA  CGACTGGATC  CCGCCTACCC  GCTCCGCCGC  ATCCAGCTCA  300
301   GACACCCAGG  TGTCCTGCGA  CCACTGCCTG  AAGGAGGTCG  CGGTGAAGAC  GTGCCTCGTG  360
361   TGCATGGCCT  CTTTCTGCCA  GGAGCACTTG  CGGCCTCACA  TCGACAGTCC  GGCCTTCCAG  420
421   GACCACCCCC  TGCAGCCACC  CGTCCGTGAC  CTGCTGCGCC  GCAAATGTTC  CAGGCACAAC  480
481   CGCCTTCGCG  AAATGTTTTG  TCCTGAGCAC  GGAGAGTGCA  TCTGCCATAT  CTGCCTGGTA  540
541   GAGCACAAGA  CCTGCTCCCC  TACGATCCTA  AGCCAGGCCA  GCGCCGACCT  GGAGAACAAA  600
601   CTGAGGCAAA  AACTCACCAT  CATGTACAGC  CACATCAATG  GAGCGAGCAA  AGCACTGGAG  660
661   GATGTGAAAT  CCAAGCAGCA  GAATGTGCAG  GAGTCTATGA  AGAGGAAGAT  GCTACAGCTG  720
721   AGACAGGAAT  ATTTGGAAAT  GAAGGCTGTC  ATCGATGCCG  CAGAGACCAG  CTCCACGCAC  780
781   AAGTTGAAGG  AGGAGGAGAA  GAGAGTCTAT  GGAAAGCTCG  ATACCATCTA  CCAGGTTCTT  840
841   CTCAAGAAGA  AGAACGAGAT  GCAGAATCTG  AAGGCAGAGG  TTGAGCTCAT  CCTGGCCAAA  900
901   GGGGACGAGT  TTGAGTTTCT  GGAGAAAGCT  GCAAAATTGC  AAGAAGTGTC  AACGAAACCA  960
961   GTCTACATCC  CTAAGATAGA  CCTGGACCAT  GATTTGATAA  AGGGGGTCTA  CCAGGGTGCA  1020
1021  TTGGACCTCA  AGAGTGAGCT  GAAGCTCTCC  CTCAAGCAGC  TACAGGAAAA  GAAGGCTGAG  1080
1081  GAGCCCTGCA  ACTCAGGTAA  CGTGGGAGAC  CATGCGCAGT  CCACATCCAA  ACCCACACGC  1140
1141  CCTGCGAAGA  AGACCGCACC  GGACAAGAAG  ACCAAGAAAA  CCCCTGGTGC  TGCGGGTGCT  1200
1201  GCCGGTGCTG  CCGGTGCTGC  TGGTGCTGCC  GGTCCTACCT  CCTACTCTTC  CTCATCTAAC  1260
1261  AAGTTGCCCA  CCTTTGGAGC  TCCTGGACAA  GCAACTATCC  CTGATGCCAC  ACTCAAACCC  1320
1321  AATGCTCCAC  AACCAAACTC  GGCAGCCGTC  AAGGCTAAGG  TGTTAGAAAA  CTTCTTAACC  1380
1381  ATGTCCAGAA  CAGAGCTTCT  GGAATATTTC  GTTAAAGTCG  TCTTCGACTA  CAATACCGCC  1440
1441  CACAACAAAG  TGGCTCTGGC  AGACAACTAC  ACCACCGCTT  CCGTGGCCGA  CGGGCTGCAG  1500
1501  CACTACCGGT  CCCATCCCCA  GAGGTTCACC  TACTGCTCTC  AGGTCCTGGG  GCTGCACTGC  1560
1561  TATAAGAAAG  GCATCCACTA  CTGGGAGGTG  GAGCTGCAGA  AGAACAACTT  CTGTGGTGTA  1620
1621  GGCGTCTGCT  ATGGCAGCAT  GGATCGGCAG  GGCCCCGAGA  GCCGGCTGGG  CCGTAACCCC  1680
1681  AGCTCATGGT  GTGTGGAGTG  GTTCAATAAC  AAGATCTCCG  CCTGGCACAA  CAACGTGGAG  1740
1741  AAAACGCTGC  CCTCCACCAA  GGCCACGCGA  GTTGGCGTGC  TACTCAACTG  TGACCATGGC  1800
1801  TTTGTCATTT  TCTTTGCTGT  CACCGAAAAG  GTGTATCTGA  TGTACAAGTT  CAAGGTGGAC  1860
1861  TTTACTGAAG  CTCTGTACCC  AGCCTTTTGG  GTGTTCTCTG  CGGGTACCAC  CCTCTCTATC  1920
1921  TGCTCCAAGT  AG  1932

▼ ANNOTATION

Disorder
D2P2IUPred2A
Interaction
RAINIIDMIST
Physicochemical
Compute pI/MwAAindex
Localization
COMPARTMENTS

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cas-2283Carlito syrichta85.641e-116 368
LLPS-Aon-2922Aotus nancymaae85.436e-119 374
LLPS-Urm-2930Ursus maritimus79.414e-110 347
LLPS-Mum-2810Mus musculus79.010.01041
LLPS-Fec-3057Felis catus78.431e-108 347
LLPS-Nol-1870Nomascus leucogenys78.079e-122 382
LLPS-Mea-1268Mesocricetus auratus76.530.0 954
LLPS-Ova-3122Ovis aries74.575e-119 369
LLPS-Otg-2657Otolemur garnettii74.125e-117 370
LLPS-Loa-0881Loxodonta africana74.050.0 546
LLPS-Orc-2066Oryctolagus cuniculus73.986e-179 528
LLPS-Mal-1769Mandrillus leucophaeus70.570.0 910
LLPS-Mup-0631Mustela putorius furo70.540.0 899
LLPS-Maf-3838Macaca fascicularis70.420.0 910
LLPS-Cea-2596Cercocebus atys70.420.0 911
LLPS-Paa-0320Papio anubis70.420.0 909
LLPS-Man-3601Macaca nemestrina70.420.0 910
LLPS-Mam-3026Macaca mulatta70.420.0 910
LLPS-Chs-1627Chlorocebus sabaeus70.110.0 908
LLPS-Rhb-1292Rhinopithecus bieti70.110.0 907
LLPS-Sus-1521Sus scrofa69.80.0 874
LLPS-Gog-1308Gorilla gorilla69.750.0 900
LLPS-Hos-1294Homo sapiens69.690.0 908
LLPS-Pap-3342Pan paniscus69.650.0 899
LLPS-Pat-3761Pan troglodytes69.650.0 899
LLPS-Ict-1463Ictidomys tridecemlineatus69.350.0 882
LLPS-Poa-2371Pongo abelii69.030.0 887
LLPS-Sah-1167Sarcophilus harrisii68.873e-96 317
LLPS-Eqc-2203Equus caballus68.450.0 881
LLPS-Bot-2477Bos taurus67.990.0 894
LLPS-Caj-1320Callithrix jacchus67.70.0 876
LLPS-Pes-1372Pelodiscus sinensis67.04e-92 306
LLPS-Cap-2984Cavia porcellus66.980.0 844
LLPS-Aim-0657Ailuropoda melanoleuca66.920.0 859
LLPS-Caf-0828Canis familiaris66.920.0 863
LLPS-Myl-0498Myotis lucifugus66.870.0 872
LLPS-Dio-1530Dipodomys ordii66.460.0 839
LLPS-Fud-3495Fukomys damarensis62.670.0 773
LLPS-Anc-1477Anolis carolinensis62.185e-84 283
LLPS-Meg-1890Meleagris gallopavo60.894e-89 296
LLPS-Gaga-3300Gallus gallus60.092e-89 297
LLPS-Fia-0826Ficedula albicollis58.915e-77 265
LLPS-Mod-3878Monodelphis domestica55.980.0 712
LLPS-Icp-1584Ictalurus punctatus51.672e-61 223
LLPS-Gaa-1016Gasterosteus aculeatus49.725e-57 209
LLPS-Dar-0916Danio rerio48.96e-59 215
LLPS-Scf-1906Scleropages formosus48.621e-58 214
LLPS-Orn-2693Oreochromis niloticus48.63e-55 204
LLPS-Orl-0794Oryzias latipes48.041e-54 202
LLPS-Xim-0193Xiphophorus maculatus48.048e-56 206
LLPS-Lac-2861Latimeria chalumnae47.851e-59 217
LLPS-Tar-3418Takifugu rubripes47.72e-48 184
LLPS-Leo-2331Lepisosteus oculatus47.062e-57 210
LLPS-Tag-0089Taeniopygia guttata46.349e-149 448
LLPS-Pof-0047Poecilia formosa43.986e-57 209
LLPS-Xet-2677Xenopus tropicalis40.474e-73 246
LLPS-Scm-2624Scophthalmus maximus34.723e-1170.5
LLPS-Ten-2891Tetraodon nigroviridis34.438e-27 119
LLPS-Asm-1559Astyanax mexicanus34.017e-26 116
LLPS-Ora-0259Ornithorhynchus anatinus31.019e-1375.1
LLPS-Tut-1516Tursiops truncatus30.96e-1374.7
LLPS-Ere-0610Erinaceus europaeus27.989e-1374.3
LLPS-Anp-3181Anas platyrhynchos24.455e-22 104