LLPS-Ran-0703
Napb

▼ OVERVIEW

Status: Unreviewed
Protein Name: Beta-soluble NSF attachment protein
Gene Name: Napb, Snapb
Ensembl Gene: ENSRNOG00000004753.6
Ensembl Protein: ENSRNOP00000006329.5
Organism: Rattus norvegicus
Taxa ID: 10116
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSRNOT00000006329.6ENSRNOP00000006329.5
UniProtP85969, SNAB_RAT, A6K7C6
GeneBankCH474026EDL95093.1
Entrez499903

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDNAGKEREA  VQLMAEAEKR  VKASHSFLRG  LFGGNTRIEE  ACEMYTRAAN  MFKMAKNWSA  60
61    AGNAFCQAAK  LHMQLQSKHD  SATSFVDAGN  AYKKADPQEA  INCLNAAIDI  YTDMGRFTIA  120
121   AKHHITIAEI  YETELVDIEK  AIAHYEQSAD  YYKGEESNSS  ANKCLLKVAA  YAAQLEQYQK  180
181   AIEIYEQVGA  NTMDNPLLKY  SAKDYFFKAA  LCHFIVDELN  AKLALEKYEE  MFPAFTDSRE  240
241   CKLLKKLLEA  HEEQNSEAYT  EAVKEFDSIS  RLDQWLTTML  LRIKKSIQGD  GEGDGDLK  298
Nucleotide CDS Sequence (FASTA)
1     ATGGACAACG  CAGGGAAAGA  ACGAGAAGCG  GTCCAGCTTA  TGGCGGAGGC  CGAGAAGCGA  60
61    GTGAAGGCTT  CCCACTCCTT  CCTCCGAGGG  TTGTTCGGAG  GAAACACAAG  AATAGAAGAG  120
121   GCATGTGAAA  TGTATACCAG  AGCTGCAAAT  ATGTTCAAGA  TGGCCAAGAA  CTGGAGTGCT  180
181   GCAGGAAATG  CATTTTGTCA  AGCCGCCAAG  CTCCACATGC  AGCTTCAGAG  CAAGCATGAC  240
241   TCTGCTACGA  GCTTTGTGGA  TGCTGGAAAT  GCTTACAAGA  AAGCAGACCC  TCAAGAGGCT  300
301   ATCAACTGCT  TAAATGCAGC  CATCGACATT  TACACAGACA  TGGGAAGATT  CACAATCGCA  360
361   GCCAAGCACC  ATATCACCAT  TGCTGAGATC  TATGAGACTG  AGCTCGTGGA  CATTGAGAAG  420
421   GCTATTGCAC  ATTATGAACA  ATCTGCTGAT  TATTACAAAG  GAGAAGAATC  TAACAGCTCT  480
481   GCTAACAAGT  GTCTGCTGAA  GGTGGCAGCC  TATGCTGCAC  AGCTGGAGCA  GTACCAGAAA  540
541   GCCATCGAGA  TCTATGAGCA  GGTGGGAGCA  AACACTATGG  ATAACCCCTT  GCTGAAGTAC  600
601   AGCGCAAAGG  ATTACTTCTT  CAAGGCAGCA  CTCTGTCACT  TCATAGTGGA  TGAGCTGAAT  660
661   GCAAAGCTTG  CTCTTGAGAA  ATACGAGGAA  ATGTTTCCAG  CATTTACTGA  CTCCAGAGAA  720
721   TGTAAATTAT  TGAAAAAACT  TCTAGAAGCT  CATGAAGAAC  AGAACAGTGA  AGCTTACACT  780
781   GAAGCAGTGA  AGGAGTTTGA  CTCAATATCA  CGTTTGGATC  AGTGGCTGAC  TACCATGTTG  840
841   CTTCGTATCA  AGAAGTCCAT  TCAAGGGGAT  GGAGAAGGAG  ATGGAGACCT  CAAGTGA  897

▼ KEYWORD

ID
Family
Complete proteome
ER-Golgi transport
Membrane
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Postsynapse
Cellular Component
Presynapse
Cellular Component
SNARE complex
Cellular Component
Synaptobrevin 2-SNAP-25-syntaxin-1a complex
Cellular Component
Vacuolar membrane
Molecular Function
SNARE binding
Molecular Function
Soluble NSF attachment protein activity
Molecular Function
Syntaxin binding
Biological Process
Intracellular protein transport
Biological Process
Protein-containing complex disassembly
Biological Process
Regulation of ATPase activity
Biological Process
Regulation of receptor internalization
Biological Process
Regulation of synaptic vesicle priming
Biological Process
SNARE complex disassembly
Biological Process
Synaptic transmission, glutamatergic

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Poa-4301Pongo abelii100.00.0 600
LLPS-Mam-3736Macaca mulatta100.00.0 600
LLPS-Cas-2623Carlito syrichta100.00.0 600
LLPS-Ict-2701Ictidomys tridecemlineatus100.00.0 600
LLPS-Pap-3709Pan paniscus100.00.0 600
LLPS-Pat-0533Pan troglodytes100.00.0 600
LLPS-Man-1192Macaca nemestrina100.00.0 600
LLPS-Orc-2103Oryctolagus cuniculus100.00.0 600
LLPS-Rhb-0938Rhinopithecus bieti100.00.0 600
LLPS-Dio-2564Dipodomys ordii100.00.0 600
LLPS-Paa-2279Papio anubis100.00.0 600
LLPS-Mum-3619Mus musculus100.00.0 600
LLPS-Maf-1998Macaca fascicularis100.00.0 600
LLPS-Cea-2107Cercocebus atys100.00.0 600
LLPS-Aon-2128Aotus nancymaae100.00.0 600
LLPS-Gog-3951Gorilla gorilla100.00.0 600
LLPS-Fud-3020Fukomys damarensis100.00.0 600
LLPS-Caf-0003Canis familiaris99.660.0 598
LLPS-Eqc-4210Equus caballus99.660.0 594
LLPS-Cap-2185Cavia porcellus99.660.0 599
LLPS-Otg-4344Otolemur garnettii99.660.0 598
LLPS-Mup-3109Mustela putorius furo99.660.0 598
LLPS-Ora-3129Ornithorhynchus anatinus99.552e-152 434
LLPS-Fec-2037Felis catus99.330.0 597
LLPS-Tut-1639Tursiops truncatus99.330.0 598
LLPS-Bot-1329Bos taurus99.330.0 598
LLPS-Ova-4479Ovis aries99.330.0 598
LLPS-Sus-2356Sus scrofa99.30.0 574
LLPS-Myl-1185Myotis lucifugus98.990.0 595
LLPS-Hos-4650Homo sapiens98.680.0 595
LLPS-Nol-1219Nomascus leucogenys98.510.0 526
LLPS-Aim-2346Ailuropoda melanoleuca98.020.0 592
LLPS-Anp-1932Anas platyrhynchos96.60.0 511
LLPS-Gaga-1982Gallus gallus96.310.0 577
LLPS-Tag-3630Taeniopygia guttata96.310.0 577
LLPS-Anc-3358Anolis carolinensis93.430.0 545
LLPS-Meg-0858Meleagris gallopavo93.160.0 562
LLPS-Urm-3219Ursus maritimus93.030.0 528
LLPS-Sah-3253Sarcophilus harrisii92.20.0 535
LLPS-Fia-3535Ficedula albicollis91.030.0 539
LLPS-Scf-2303Scleropages formosus90.270.0 549
LLPS-Icp-3242Ictalurus punctatus87.920.0 538
LLPS-Dar-1722Danio rerio87.580.0 538
LLPS-Asm-3464Astyanax mexicanus87.580.0 538
LLPS-Pes-0894Pelodiscus sinensis86.783e-151 431
LLPS-Orl-2314Oryzias latipes84.620.0 516
LLPS-Mal-1540Mandrillus leucophaeus84.252e-173 489
LLPS-Chs-1390Chlorocebus sabaeus84.252e-173 489
LLPS-Caj-4551Callithrix jacchus84.255e-174 491
LLPS-Loa-3215Loxodonta africana83.91e-173 489
LLPS-Mea-0550Mesocricetus auratus83.222e-173 489
LLPS-Mod-3771Monodelphis domestica82.889e-172 485
LLPS-Lac-3616Latimeria chalumnae82.550.0 509
LLPS-Xet-2078Xenopus tropicalis81.852e-179 504
LLPS-Leo-2583Lepisosteus oculatus81.636e-176 496
LLPS-Orn-4122Oreochromis niloticus80.279e-170 480
LLPS-Pof-2868Poecilia formosa80.06e-161 457
LLPS-Xim-3245Xiphophorus maculatus79.662e-160 456
LLPS-Gaa-0216Gasterosteus aculeatus79.263e-169 479
LLPS-Ten-1206Tetraodon nigroviridis78.455e-166 470
LLPS-Scm-2363Scophthalmus maximus77.522e-168 477
LLPS-Tar-3303Takifugu rubripes76.875e-163 463
LLPS-Drm-0777Drosophila melanogaster61.991e-124 365
LLPS-Cis-1190Ciona savignyi60.852e-98 296
LLPS-Cii-1162Ciona intestinalis57.487e-118 348
LLPS-Cae-0013Caenorhabditis elegans50.346e-100 302
LLPS-Sem-0058Selaginella moellendorffii47.967e-79 248
LLPS-Fus-0982Fusarium solani46.091e-54 184
LLPS-Vir-1123Vigna radiata45.731e-52 179
LLPS-Viv-0524Vitis vinifera45.385e-71 228
LLPS-Mae-0688Manihot esculenta45.353e-76 241
LLPS-Amt-2116Amborella trichopoda44.244e-67 218
LLPS-Php-0193Physcomitrella patens44.015e-67 218
LLPS-Thc-1242Theobroma cacao43.874e-75 238
LLPS-Hea-2552Helianthus annuus43.823e-69 223
LLPS-Pot-0738Populus trichocarpa43.735e-69 223
LLPS-Coc-1382Corchorus capsularis43.492e-74 236
LLPS-Bro-0899Brassica oleracea43.491e-67 221
LLPS-Art-2190Arabidopsis thaliana43.492e-68 221
LLPS-Brr-0880Brassica rapa43.499e-72 230
LLPS-Brn-2517Brassica napus43.497e-68 220
LLPS-Ori-1043Oryza indica43.245e-32 122
LLPS-Arl-2448Arabidopsis lyrata43.126e-68 220
LLPS-Fuo-1458Fusarium oxysporum42.962e-60 201
LLPS-Fuv-1090Fusarium verticillioides42.968e-61 202
LLPS-Cogr-1398Colletotrichum graminicola42.912e-58 195
LLPS-Coo-1008Colletotrichum orbiculare42.913e-57 192
LLPS-Scs-1022Sclerotinia sclerotiorum42.643e-60 200
LLPS-Ved-0824Verticillium dahliae42.522e-57 193
LLPS-Orp-0758Oryza punctata42.383e-64 210
LLPS-Gas-0763Galdieria sulphuraria41.891e-60 201
LLPS-Orr-2400Oryza rufipogon41.643e-62 205
LLPS-Orm-2000Oryza meridionalis41.641e-62 206
LLPS-Org-0178Oryza glaberrima41.643e-62 205
LLPS-Ors-1544Oryza sativa41.643e-62 205
LLPS-Phv-1273Phaseolus vulgaris41.645e-72 230
LLPS-Orgl-2353Oryza glumaepatula41.643e-62 205
LLPS-Glm-2776Glycine max41.646e-72 230
LLPS-Orb-1446Oryza barthii41.643e-62 205
LLPS-Orni-1075Oryza nivara41.643e-62 205
LLPS-Map-0223Magnaporthe poae41.583e-54 184
LLPS-Pug-0968Puccinia graminis41.55e-62 204
LLPS-Blg-1395Blumeria graminis41.491e-59 199
LLPS-Mel-1079Melampsora laricipopulina41.372e-66 216
LLPS-Put-0857Puccinia triticina41.347e-60 199
LLPS-Lep-0952Leersia perrieri41.265e-63 207
LLPS-Mua-1762Musa acuminata41.263e-66 216
LLPS-Gag-1615Gaeumannomyces graminis41.224e-54 184
LLPS-Gor-2636Gossypium raimondii41.058e-72 230
LLPS-Sei-1541Setaria italica41.048e-62 204
LLPS-Asni-1207Aspergillus niger41.035e-47 166
LLPS-Zyt-0800Zymoseptoria tritici40.995e-55 186
LLPS-Cog-0892Colletotrichum gloeosporioides40.942e-50 174
LLPS-Prp-2056Prunus persica40.895e-68 220
LLPS-Asc-1515Aspergillus clavatus40.894e-54 185
LLPS-Nef-0785Neosartorya fischeri40.869e-56 188
LLPS-Mao-1204Magnaporthe oryzae40.863e-55 187
LLPS-Cym-0850Cyanidioschyzon merolae40.812e-56 191
LLPS-Beb-1092Beauveria bassiana40.655e-58 194
LLPS-Sob-1994Sorghum bicolor40.521e-61 203
LLPS-Nia-1158Nicotiana attenuata40.524e-66 215
LLPS-Cus-0877Cucumis sativus40.528e-66 214
LLPS-Asfu-1053Aspergillus fumigatus40.54e-54 184
LLPS-Via-2332Vigna angularis40.493e-71 228
LLPS-Abg-1568Absidia glauca40.488e-63 207
LLPS-Dos-1208Dothistroma septosporum40.386e-56 189
LLPS-Orbr-1526Oryza brachyantha40.155e-61 202
LLPS-Brd-0293Brachypodium distachyon40.156e-61 202
LLPS-Asn-0011Aspergillus nidulans39.865e-56 189
LLPS-Osl-0513Ostreococcus lucimarinus39.854e-49 171
LLPS-Tra-1883Triticum aestivum39.783e-61 202
LLPS-Dac-0049Daucus carota39.625e-59 196
LLPS-Chr-1587Chlamydomonas reinhardtii39.078e-52 178
LLPS-Aso-0786Aspergillus oryzae38.872e-53 182
LLPS-Asf-0000Aspergillus flavus38.872e-53 182
LLPS-Zem-1232Zea mays38.661e-55 188
LLPS-Sol-1188Solanum lycopersicum38.661e-62 206
LLPS-Lem-1565Leptosphaeria maculans38.64e-44 159
LLPS-Met-2054Medicago truncatula38.63e-68 221
LLPS-Nec-0199Neurospora crassa38.352e-45 161
LLPS-Pyt-0641Pyrenophora teres38.331e-44 159
LLPS-Scp-0199Schizosaccharomyces pombe38.135e-57 191
LLPS-Yal-1042Yarrowia lipolytica38.119e-57 191
LLPS-Phn-1351Phaeosphaeria nodorum38.066e-36 135
LLPS-Pytr-1343Pyrenophora triticirepentis37.891e-40 149
LLPS-Sot-1588Solanum tuberosum37.637e-63 207
LLPS-Ast-0499Aspergillus terreus37.545e-52 179
LLPS-Scj-0771Schizosaccharomyces japonicus37.411e-53 183
LLPS-Tum-1333Tuber melanosporum37.414e-52 179
LLPS-Chc-1001Chondrus crispus37.382e-54 185
LLPS-Scc-1494Schizosaccharomyces cryophilus37.052e-53 182
LLPS-Asg-0833Ashbya gossypii35.593e-48 169
LLPS-Tru-1952Triticum urartu35.564e-48 171
LLPS-Crn-1459Cryptococcus neoformans35.216e-46 162
LLPS-Kop-0638Komagataella pastoris35.141e-48 170
LLPS-Sac-1338Saccharomyces cerevisiae34.515e-41 150
LLPS-Miv-1253Microbotryum violaceum34.044e-42 152
LLPS-Usm-1135Ustilago maydis33.696e-43 155
LLPS-Spr-1161Sporisorium reilianum33.457e-42 152
LLPS-Trv-1627Trichoderma virens32.752e-29 118
LLPS-Trr-0535Trichoderma reesei31.347e-27 111