LLPS-Ran-0699
Nol12

▼ OVERVIEW

Status: Unreviewed
Protein Name: Nucleolar protein 12; 25 kDa nucleolar protein
Gene Name: Nol12, Nop25
Ensembl Gene: ENSRNOG00000010209.7
Ensembl Protein: ENSRNOP00000013764.3
Organism: Rattus norvegicus
Taxa ID: 10116
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Paraspeckle, P-bodyPredicted from orthologs(View)

▼ FUNCTION

May bind to 28S rRNA.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGRNKKKKRD  GDDRRPRLIL  NFDEEKRREY  LTGFHKRKVE  RKKAAIEEIK  QRLKQEQKKL  60
61    REERHQEYLK  MLAEREEALE  EADELERLVT  AKTESVQYDH  PNHTVTVTTV  SDLDLSGARL  120
121   LGLPLPEQGD  QDGSQEEEVS  SMEKPTKALP  KKSKDPLLSQ  RISSLTATLH  AHSRKKVKRK  180
181   HPRRAQDSTK  KPPSATRTSK  TQRRRRMTGK  ARHNGE  216
Nucleotide CDS Sequence (FASTA)
1     ATGGGCCGCA  ACAAGAAGAA  AAAAAGAGAT  GGAGATGACC  GGCGTCCCCG  GCTCATCCTC  60
61    AACTTTGATG  AAGAGAAGCG  GCGGGAATAC  CTGACAGGCT  TCCACAAGCG  GAAGGTAGAG  120
121   CGCAAGAAGG  CAGCCATTGA  AGAGATAAAG  CAGCGGCTTA  AGCAAGAGCA  GAAGAAGCTT  180
181   CGGGAAGAGC  GCCACCAGGA  GTACCTGAAG  ATGCTGGCAG  AAAGAGAGGA  GGCACTAGAG  240
241   GAGGCCGATG  AGCTGGAGCG  GCTGGTGACA  GCAAAGACAG  AGTCGGTGCA  GTACGACCAT  300
301   CCCAATCACA  CAGTCACTGT  GACCACCGTC  AGTGACCTGG  ACCTCTCAGG  GGCCCGGCTG  360
361   CTAGGTCTAC  CCCTGCCTGA  GCAAGGGGAC  CAGGATGGGT  CCCAGGAGGA  GGAGGTGTCA  420
421   TCCATGGAAA  AGCCAACAAA  AGCCTTGCCC  AAGAAGTCCA  AGGATCCCCT  GCTCTCTCAG  480
481   CGCATCTCCT  CCCTCACAGC  TACACTGCAT  GCACACAGTC  GGAAGAAGGT  CAAGAGGAAA  540
541   CACCCTCGGC  GGGCGCAGGA  CTCCACCAAG  AAACCTCCAA  GTGCCACTCG  TACCAGCAAG  600
601   ACCCAGCGCC  GCCGTCGGAT  GACTGGAAAA  GCCAGGCACA  ACGGGGAGTG  A  651

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Nucleus
Reference proteome
RNA-binding
rRNA-binding

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleolus
Cellular Component
Nucleus
Molecular Function
RNA binding
Molecular Function
RRNA binding
Molecular Function
Single-stranded DNA binding
Biological Process
Negative regulation of apoptotic process
Biological Process
Nucleolus organization
Biological Process
Positive regulation of cell growth
Biological Process
Positive regulation of cell population proliferation
Biological Process
RRNA processing

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mum-2037Mus musculus97.513e-87 264
LLPS-Mea-2012Mesocricetus auratus94.531e-81 249
LLPS-Ict-3197Ictidomys tridecemlineatus89.055e-69 217
LLPS-Myl-1938Myotis lucifugus88.061e-77 239
LLPS-Fud-1156Fukomys damarensis87.941e-74 231
LLPS-Ova-1654Ovis aries87.51e-72 226
LLPS-Otg-2800Otolemur garnettii87.196e-66 209
LLPS-Sus-4434Sus scrofa87.064e-75 233
LLPS-Cas-0682Carlito syrichta87.062e-75 233
LLPS-Caf-0414Canis familiaris87.063e-75 233
LLPS-Aon-0418Aotus nancymaae86.572e-67 213
LLPS-Bot-0118Bos taurus86.57e-59 191
LLPS-Gog-0421Gorilla gorilla86.079e-72 224
LLPS-Urm-0683Ursus maritimus86.072e-75 233
LLPS-Pap-3364Pan paniscus86.075e-72 224
LLPS-Hos-1883Homo sapiens86.073e-71 223
LLPS-Loa-0758Loxodonta africana86.074e-64 204
LLPS-Eqc-1668Equus caballus86.075e-76 235
LLPS-Cea-1116Cercocebus atys85.934e-70 220
LLPS-Pat-0592Pan troglodytes85.573e-71 223
LLPS-Cap-0545Cavia porcellus85.571e-64 206
LLPS-Maf-1695Macaca fascicularis85.432e-70 221
LLPS-Rhb-0129Rhinopithecus bieti85.435e-70 219
LLPS-Man-0635Macaca nemestrina85.432e-70 221
LLPS-Paa-0105Papio anubis85.072e-71 223
LLPS-Fec-0473Felis catus85.077e-73 227
LLPS-Mam-0168Macaca mulatta84.927e-70 219
LLPS-Chs-0578Chlorocebus sabaeus84.581e-71 223
LLPS-Ere-0075Erinaceus europaeus84.585e-70 219
LLPS-Mup-0778Mustela putorius furo84.583e-64 205
LLPS-Orc-1365Oryctolagus cuniculus82.591e-62 201
LLPS-Caj-3460Callithrix jacchus82.091e-65 208
LLPS-Aim-0298Ailuropoda melanoleuca81.465e-73 227
LLPS-Xet-1485Xenopus tropicalis76.922e-0651.2
LLPS-Ora-0639Ornithorhynchus anatinus74.075e-42 147
LLPS-Poa-1298Pongo abelii70.659e-53 175
LLPS-Pes-1651Pelodiscus sinensis69.234e-42 148
LLPS-Sah-1873Sarcophilus harrisii68.715e-36 130
LLPS-Nol-2049Nomascus leucogenys67.821e-48 164
LLPS-Anc-0703Anolis carolinensis67.493e-41 145
LLPS-Meg-2525Meleagris gallopavo66.11e-37 136
LLPS-Tag-1956Taeniopygia guttata65.821e-44 154
LLPS-Gaga-2366Gallus gallus64.572e-40 143
LLPS-Fia-0097Ficedula albicollis63.357e-37 135
LLPS-Mod-2932Monodelphis domestica62.873e-45 156
LLPS-Anp-1005Anas platyrhynchos61.042e-25 104
LLPS-Asm-1409Astyanax mexicanus60.788e-25 102
LLPS-Dar-1725Danio rerio59.745e-2397.8
LLPS-Lac-0654Latimeria chalumnae56.483e-27 108
LLPS-Icp-0448Ictalurus punctatus51.471e-26 107
LLPS-Scm-1857Scophthalmus maximus50.312e-2193.6
LLPS-Scf-0801Scleropages formosus49.774e-24 100
LLPS-Orl-0989Oryzias latipes47.835e-25 103
LLPS-Orn-0131Oreochromis niloticus47.373e-26 106
LLPS-Ten-0737Tetraodon nigroviridis46.579e-27 108
LLPS-Xim-3133Xiphophorus maculatus46.154e-2089.7
LLPS-Pof-2382Poecilia formosa44.083e-1987.8
LLPS-Gaa-0379Gasterosteus aculeatus43.967e-2294.7
LLPS-Tar-0872Takifugu rubripes43.068e-24 100