LLPS-Ran-0186
Slc25a20
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Mitochondrial carnitine/acylcarnitine carrier protein; Carnitine/acylcarnitine translocase; CAC; Solute carrier family 25 member 20 |
| Gene Name: | Slc25a20, Cact |
| Ensembl Gene: | ENSRNOG00000020288.4 |
| Ensembl Protein: | ENSRNOP00000027520.2 |
| Organism: | Rattus norvegicus |
| Taxa ID: | 10116 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSRNOT00000027520.4 | ENSRNOP00000027520.2 |
| UniProt | P97521, MCAT_RAT | |
| GeneBank | X97831 | CAA66410.1 |
| Entrez | 117035 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAEEPKPISP LKNLLAGGFG GVCLVFVGHP LDTVKVRLQT QPPSLPGQPP MYSGTIDCFR 60 61 KTLFREGITG LYRGMAAPII GVTPMFAVCF FGFGLGKRLQ QKSPEDELTY PQLFTAGMLS 120 121 GVFTTGIMTP GERIKCLLQI QASSGKNKYS GTLDCAKKLY QEFGIRGFYK GTVLTLMRDV 180 181 PASGMYFMTY EWLKNLFTPQ GKSVHDLSVP RVLVAGGFAG IFNWVVAIPP DVLKSRFQTA 240 241 PPGKYPNGFR DVLRELIREE GVTSLYKGFN AVMIRAFPAN AACFLGFEIA MKILNWIAPN 300 301 L 301 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCAGAGG AGCCGAAACC CATCAGTCCG CTTAAGAACC TCCTTGCCGG CGGCTTTGGC 60 61 GGCGTGTGCC TGGTGTTTGT GGGGCACCCC TTGGACACGG TCAAGGTCCG ACTGCAGACA 120 121 CAACCACCAA GTTTGCCTGG GCAGCCACCT ATGTACTCTG GGACCATCGA CTGTTTCCGG 180 181 AAGACTCTTT TTAGAGAGGG CATCACAGGG CTGTATCGGG GCATGGCTGC ACCCATCATT 240 241 GGAGTCACCC CTATGTTTGC CGTGTGCTTC TTTGGGTTTG GTTTGGGGAA GAGACTACAG 300 301 CAGAAATCTC CAGAGGATGA ACTTACCTAC CCGCAGCTGT TTACAGCTGG GATGTTATCT 360 361 GGTGTGTTCA CCACAGGAAT CATGACCCCT GGAGAACGGA TCAAATGCTT ACTGCAGATT 420 421 CAGGCTTCTT CAGGGAAAAA CAAATACAGT GGTACCTTGG ACTGTGCAAA GAAGCTGTAT 480 481 CAGGAGTTTG GGATCCGTGG CTTCTACAAA GGGACTGTGC TCACTCTCAT GCGAGATGTT 540 541 CCTGCCAGTG GGATGTATTT CATGACATAC GAATGGCTTA AAAATCTCTT CACTCCACAG 600 601 GGAAAGAGTG TCCATGACCT CAGTGTGCCT CGGGTCCTGG TGGCTGGCGG CTTTGCAGGG 660 661 ATCTTCAATT GGGTTGTGGC AATCCCCCCA GACGTGCTCA AGTCTCGATT CCAGACCGCA 720 721 CCTCCTGGAA AATATCCTAA TGGTTTCAGA GATGTGTTGA GAGAGCTGAT CCGAGAAGAA 780 781 GGAGTCACCT CCTTGTACAA AGGGTTCAAT GCAGTCATGA TCCGAGCCTT CCCAGCCAAT 840 841 GCTGCCTGTT TCCTTGGCTT TGAAATTGCC ATGAAGATCC TCAATTGGAT TGCCCCCAAC 900 901 TTGTGA 906 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Integral component of membrane | |
Cellular Component | Mitochondrial inner membrane | |
Molecular Function | Transmembrane transporter activity | |
Biological Process | Carnitine transmembrane transport |
▼ ANNOTATION
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| RaftProt | ||||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | TISSUES | |||
| Element | ||||
| miRWalk | RAID | microRNA.org | ||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Mum-4470 | Mus musculus | 95.35 | 0.0 | 560 |
| LLPS-Mea-3436 | Mesocricetus auratus | 94.35 | 0.0 | 554 |
| LLPS-Chs-3043 | Chlorocebus sabaeus | 91.69 | 0.0 | 539 |
| LLPS-Hos-4310 | Homo sapiens | 91.36 | 0.0 | 538 |
| LLPS-Pat-1525 | Pan troglodytes | 91.36 | 0.0 | 538 |
| LLPS-Pap-0101 | Pan paniscus | 91.36 | 0.0 | 538 |
| LLPS-Mam-2178 | Macaca mulatta | 91.36 | 0.0 | 536 |
| LLPS-Poa-2267 | Pongo abelii | 91.36 | 0.0 | 537 |
| LLPS-Nol-2693 | Nomascus leucogenys | 91.36 | 0.0 | 538 |
| LLPS-Aon-3180 | Aotus nancymaae | 91.36 | 0.0 | 536 |
| LLPS-Cea-1210 | Cercocebus atys | 91.36 | 0.0 | 536 |
| LLPS-Maf-0561 | Macaca fascicularis | 91.36 | 0.0 | 536 |
| LLPS-Paa-0000 | Papio anubis | 91.36 | 0.0 | 536 |
| LLPS-Mal-4170 | Mandrillus leucophaeus | 91.36 | 0.0 | 536 |
| LLPS-Ict-1073 | Ictidomys tridecemlineatus | 90.7 | 0.0 | 540 |
| LLPS-Fud-3325 | Fukomys damarensis | 90.7 | 0.0 | 537 |
| LLPS-Caj-2826 | Callithrix jacchus | 90.7 | 0.0 | 534 |
| LLPS-Gog-2929 | Gorilla gorilla | 90.7 | 0.0 | 536 |
| LLPS-Fec-0943 | Felis catus | 90.37 | 0.0 | 533 |
| LLPS-Orc-3565 | Oryctolagus cuniculus | 90.03 | 0.0 | 533 |
| LLPS-Aim-0604 | Ailuropoda melanoleuca | 90.03 | 0.0 | 533 |
| LLPS-Caf-2558 | Canis familiaris | 89.7 | 0.0 | 530 |
| LLPS-Cap-4000 | Cavia porcellus | 89.37 | 0.0 | 524 |
| LLPS-Mup-3835 | Mustela putorius furo | 89.37 | 0.0 | 528 |
| LLPS-Cas-3798 | Carlito syrichta | 89.04 | 0.0 | 525 |
| LLPS-Ova-3207 | Ovis aries | 88.78 | 0.0 | 524 |
| LLPS-Loa-2562 | Loxodonta africana | 88.76 | 2e-176 | 495 |
| LLPS-Bot-2218 | Bos taurus | 88.7 | 0.0 | 527 |
| LLPS-Myl-3269 | Myotis lucifugus | 88.04 | 0.0 | 521 |
| LLPS-Urm-1112 | Ursus maritimus | 87.38 | 0.0 | 526 |
| LLPS-Sus-1705 | Sus scrofa | 87.38 | 0.0 | 520 |
| LLPS-Gaga-1008 | Gallus gallus | 85.38 | 1e-170 | 483 |
| LLPS-Tag-3243 | Taeniopygia guttata | 84.59 | 1e-166 | 471 |
| LLPS-Fia-1454 | Ficedula albicollis | 84.39 | 3e-177 | 499 |
| LLPS-Sah-3129 | Sarcophilus harrisii | 84.12 | 4e-171 | 484 |
| LLPS-Eqc-4357 | Equus caballus | 83.39 | 2e-162 | 461 |
| LLPS-Pes-1711 | Pelodiscus sinensis | 81.72 | 3e-163 | 462 |
| LLPS-Anc-2297 | Anolis carolinensis | 81.25 | 1e-172 | 488 |
| LLPS-Orn-3240 | Oreochromis niloticus | 80.73 | 7e-171 | 483 |
| LLPS-Xet-3744 | Xenopus tropicalis | 80.73 | 4e-173 | 489 |
| LLPS-Dar-3664 | Danio rerio | 80.41 | 1e-166 | 472 |
| LLPS-Xim-1979 | Xiphophorus maculatus | 80.07 | 5e-171 | 483 |
| LLPS-Orl-3628 | Oryzias latipes | 79.47 | 3e-168 | 476 |
| LLPS-Pof-0695 | Poecilia formosa | 79.07 | 5e-170 | 481 |
| LLPS-Gaa-1790 | Gasterosteus aculeatus | 78.57 | 5e-162 | 461 |
| LLPS-Mod-4382 | Monodelphis domestica | 75.25 | 7e-157 | 447 |
| LLPS-Lac-1050 | Latimeria chalumnae | 74.75 | 3e-150 | 431 |
| LLPS-Leo-1613 | Lepisosteus oculatus | 68.79 | 4e-144 | 415 |
| LLPS-Scf-1183 | Scleropages formosus | 65.33 | 4e-137 | 397 |
| LLPS-Icp-3420 | Ictalurus punctatus | 64.55 | 1e-129 | 378 |
| LLPS-Asm-1627 | Astyanax mexicanus | 64.36 | 4e-133 | 387 |
| LLPS-Scm-2356 | Scophthalmus maximus | 64.0 | 5e-129 | 377 |
| LLPS-Tar-1913 | Takifugu rubripes | 64.0 | 9e-129 | 376 |
| LLPS-Cii-2062 | Ciona intestinalis | 62.67 | 6e-92 | 280 |
| LLPS-Cis-1845 | Ciona savignyi | 61.68 | 6e-116 | 343 |
| LLPS-Cae-0492 | Caenorhabditis elegans | 54.98 | 3e-97 | 296 |
| LLPS-Drm-2058 | Drosophila melanogaster | 52.19 | 2e-102 | 309 |
| LLPS-Miv-0186 | Microbotryum violaceum | 46.89 | 4e-78 | 248 |
| LLPS-Mel-1332 | Melampsora laricipopulina | 46.72 | 3e-80 | 253 |
| LLPS-Crn-0771 | Cryptococcus neoformans | 46.24 | 1e-76 | 243 |
| LLPS-Pug-1466 | Puccinia graminis | 46.18 | 4e-79 | 250 |
| LLPS-Put-0131 | Puccinia triticina | 44.96 | 8e-79 | 250 |
| LLPS-Spr-1185 | Sporisorium reilianum | 44.32 | 3e-73 | 234 |
| LLPS-Tum-1527 | Tuber melanosporum | 43.91 | 3e-66 | 216 |
| LLPS-Usm-1009 | Ustilago maydis | 43.64 | 9e-73 | 233 |
| LLPS-Mae-1327 | Manihot esculenta | 42.96 | 2e-57 | 193 |
| LLPS-Scs-1030 | Sclerotinia sclerotiorum | 42.4 | 6e-59 | 198 |
| LLPS-Pyt-0539 | Pyrenophora teres | 42.29 | 4e-60 | 201 |
| LLPS-Fuo-0911 | Fusarium oxysporum | 42.2 | 1e-62 | 207 |
| LLPS-Fus-0512 | Fusarium solani | 42.14 | 7e-62 | 206 |
| LLPS-Zyt-1589 | Zymoseptoria tritici | 41.94 | 6e-61 | 204 |
| LLPS-Gas-1017 | Galdieria sulphuraria | 41.85 | 2e-63 | 209 |
| LLPS-Fuv-0258 | Fusarium verticillioides | 41.84 | 3e-62 | 207 |
| LLPS-Viv-1950 | Vitis vinifera | 41.73 | 7e-42 | 153 |
| LLPS-Met-0235 | Medicago truncatula | 41.73 | 2e-55 | 188 |
| LLPS-Prp-0151 | Prunus persica | 41.58 | 5e-58 | 194 |
| LLPS-Mua-0723 | Musa acuminata | 41.54 | 1e-54 | 186 |
| LLPS-Coo-0907 | Colletotrichum orbiculare | 41.37 | 3e-54 | 186 |
| LLPS-Nia-2468 | Nicotiana attenuata | 41.33 | 3e-55 | 187 |
| LLPS-Thc-0399 | Theobroma cacao | 41.03 | 9e-56 | 189 |
| LLPS-Php-2514 | Physcomitrella patens | 41.02 | 6e-56 | 189 |
| LLPS-Cus-0511 | Cucumis sativus | 40.86 | 1e-53 | 183 |
| LLPS-Pot-1691 | Populus trichocarpa | 40.66 | 3e-52 | 179 |
| LLPS-Amt-1747 | Amborella trichopoda | 40.65 | 6e-49 | 171 |
| LLPS-Gag-0805 | Gaeumannomyces graminis | 40.57 | 3e-60 | 201 |
| LLPS-Mao-0685 | Magnaporthe oryzae | 40.57 | 3e-61 | 204 |
| LLPS-Cogr-0046 | Colletotrichum graminicola | 40.5 | 1e-54 | 187 |
| LLPS-Glm-2679 | Glycine max | 40.5 | 2e-53 | 183 |
| LLPS-Sol-2403 | Solanum lycopersicum | 40.5 | 3e-53 | 182 |
| LLPS-Sot-1533 | Solanum tuberosum | 40.5 | 3e-54 | 185 |
| LLPS-Via-0240 | Vigna angularis | 40.43 | 2e-55 | 187 |
| LLPS-Gor-0005 | Gossypium raimondii | 40.36 | 5e-54 | 184 |
| LLPS-Dos-1367 | Dothistroma septosporum | 40.21 | 1e-58 | 197 |
| LLPS-Nec-0550 | Neurospora crassa | 40.21 | 2e-61 | 205 |
| LLPS-Coc-1574 | Corchorus capsularis | 40.14 | 4e-52 | 179 |
| LLPS-Dac-2181 | Daucus carota | 40.07 | 3e-56 | 190 |
| LLPS-Vir-2112 | Vigna radiata | 39.93 | 4e-52 | 179 |
| LLPS-Ved-1150 | Verticillium dahliae | 39.86 | 8e-51 | 177 |
| LLPS-Phv-1732 | Phaseolus vulgaris | 39.57 | 2e-51 | 177 |
| LLPS-Brr-2170 | Brassica rapa | 39.29 | 1e-52 | 181 |
| LLPS-Bro-1034 | Brassica oleracea | 39.29 | 2e-52 | 180 |
| LLPS-Brn-1137 | Brassica napus | 39.29 | 1e-52 | 181 |
| LLPS-Hea-2672 | Helianthus annuus | 39.06 | 6e-53 | 182 |
| LLPS-Art-0006 | Arabidopsis thaliana | 39.01 | 2e-51 | 177 |
| LLPS-Sob-1275 | Sorghum bicolor | 38.41 | 5e-48 | 168 |
| LLPS-Lep-1772 | Leersia perrieri | 37.91 | 3e-44 | 164 |
| LLPS-Orbr-0079 | Oryza brachyantha | 37.63 | 5e-39 | 145 |
| LLPS-Tra-1999 | Triticum aestivum | 37.55 | 2e-45 | 162 |
| LLPS-Arl-2052 | Arabidopsis lyrata | 37.46 | 4e-48 | 169 |
| LLPS-Sem-2163 | Selaginella moellendorffii | 37.37 | 4e-46 | 163 |
| LLPS-Ors-2138 | Oryza sativa | 37.09 | 3e-43 | 156 |
| LLPS-Org-1290 | Oryza glaberrima | 37.09 | 3e-43 | 156 |
| LLPS-Ori-2101 | Oryza indica | 37.09 | 3e-43 | 156 |
| LLPS-Brd-0383 | Brachypodium distachyon | 37.04 | 2e-42 | 154 |
| LLPS-Orr-0648 | Oryza rufipogon | 36.64 | 1e-39 | 153 |
| LLPS-Orni-1125 | Oryza nivara | 36.47 | 3e-35 | 138 |
| LLPS-Sei-0577 | Setaria italica | 36.15 | 7e-38 | 142 |
| LLPS-Orb-0899 | Oryza barthii | 36.08 | 1e-34 | 136 |
| LLPS-Orgl-0073 | Oryza glumaepatula | 35.81 | 3e-39 | 151 |
| LLPS-Orp-2119 | Oryza punctata | 35.69 | 4e-37 | 140 |
| LLPS-Tru-0536 | Triticum urartu | 35.69 | 4e-31 | 123 |
| LLPS-Kop-1316 | Komagataella pastoris | 35.47 | 9e-39 | 144 |
| LLPS-Ten-3554 | Tetraodon nigroviridis | 34.88 | 7e-07 | 53.9 |
| LLPS-Asg-0179 | Ashbya gossypii | 34.52 | 2e-43 | 157 |
| LLPS-Ast-1483 | Aspergillus terreus | 33.7 | 4e-37 | 140 |
| LLPS-Yal-1334 | Yarrowia lipolytica | 33.57 | 2e-39 | 146 |
| LLPS-Anp-2169 | Anas platyrhynchos | 33.45 | 6e-34 | 131 |
| LLPS-Meg-0682 | Meleagris gallopavo | 33.45 | 9e-34 | 130 |
| LLPS-Scj-0835 | Schizosaccharomyces japonicus | 33.09 | 2e-37 | 140 |
| LLPS-Map-0939 | Magnaporthe poae | 32.98 | 2e-18 | 87.4 |
| LLPS-Chr-0639 | Chlamydomonas reinhardtii | 32.98 | 1e-39 | 147 |
| LLPS-Abg-0678 | Absidia glauca | 32.89 | 3e-38 | 142 |
| LLPS-Scc-1215 | Schizosaccharomyces cryophilus | 32.8 | 5e-20 | 91.7 |
| LLPS-Asni-0882 | Aspergillus niger | 32.62 | 4e-37 | 140 |
| LLPS-Asc-0277 | Aspergillus clavatus | 32.6 | 2e-34 | 133 |
| LLPS-Tut-0278 | Tursiops truncatus | 32.5 | 6e-21 | 94.7 |
| LLPS-Man-1479 | Macaca nemestrina | 32.49 | 9e-22 | 97.1 |
| LLPS-Rhb-3680 | Rhinopithecus bieti | 32.49 | 1e-21 | 96.7 |
| LLPS-Scp-0953 | Schizosaccharomyces pombe | 32.45 | 5e-29 | 117 |
| LLPS-Osl-1237 | Ostreococcus lucimarinus | 32.26 | 6e-37 | 139 |
| LLPS-Asn-1064 | Aspergillus nidulans | 32.25 | 1e-32 | 128 |
| LLPS-Ere-0966 | Erinaceus europaeus | 32.23 | 3e-30 | 120 |
| LLPS-Sac-1360 | Saccharomyces cerevisiae | 32.12 | 2e-33 | 130 |
| LLPS-Otg-0332 | Otolemur garnettii | 32.0 | 1e-31 | 125 |
| LLPS-Chc-0911 | Chondrus crispus | 31.9 | 6e-31 | 121 |
| LLPS-Trr-0497 | Trichoderma reesei | 31.89 | 1e-27 | 114 |
| LLPS-Trv-1551 | Trichoderma virens | 31.88 | 2e-26 | 110 |
| LLPS-Beb-1270 | Beauveria bassiana | 31.67 | 5e-27 | 112 |
| LLPS-Asfu-0853 | Aspergillus fumigatus | 31.5 | 3e-36 | 138 |
| LLPS-Aso-0642 | Aspergillus oryzae | 31.41 | 3e-33 | 130 |
| LLPS-Asf-0526 | Aspergillus flavus | 31.41 | 3e-33 | 130 |
| LLPS-Cog-0597 | Colletotrichum gloeosporioides | 31.35 | 1e-16 | 82.0 |
| LLPS-Blg-0799 | Blumeria graminis | 31.29 | 1e-38 | 144 |
| LLPS-Ora-2844 | Ornithorhynchus anatinus | 31.27 | 1e-30 | 122 |
| LLPS-Nef-1495 | Neosartorya fischeri | 30.86 | 3e-20 | 92.4 |
| LLPS-Phn-1154 | Phaeosphaeria nodorum | 30.41 | 2e-16 | 81.6 |
| LLPS-Lem-0512 | Leptosphaeria maculans | 29.78 | 2e-24 | 104 |
| LLPS-Pytr-0526 | Pyrenophora triticirepentis | 29.41 | 4e-25 | 107 |