• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Pytr-0240
PTRG_03897

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Eukaryotic translation initiation factor 3 subunit F
Gene Name: PTRG_03897
Ensembl Gene: PTRG_03897
Ensembl Protein: EDU46735
Organism: Pyrenophora triticirepentis
Taxa ID: 426418
LLPS Type: LLPS regulator


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
P-body, Stress granule, OthersPredicted from orthologs(View)

▼ FUNCTION


Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

▼ CROSS REFERENCE


DatabaseNucleotide IDProtein ID
EnsemblEDU46735EDU46735
UniProtB2W0B2, B2W0B2_PYRTR
GeneBankDS231617EDU46735.1
RefSeqXM_001934195.1XP_001934230.1

▼ SEQUENCE


Protein Sequence (FASTA)
1     MAATDSFLHL  ARPLGPAPLG  AQPSTAPLNV  AIQPQAVFSI  LDHSLRRPAD  QERVIGTLLG  60
61    TRSEDGTEIE  IRNCYAVPHT  ETAEQVEVDM  DYQKSMLALH  LRANPREVLV  GWYATSSDLN  120
121   TFSALIQNFY  SQQGDGTWPH  PAVHLTVSTV  PGQDIESKTY  ISAPIGVTAE  RAADSCLFIP  180
181   VPHEIKYGEA  ERSGLELISS  AKDREDRSQE  VMTDLDSLER  AIQHVLDMLE  RVSNYVNNVL  240
241   DEEAEPSSAL  GQFLMNALSL  APKVEPADIE  RDFNAHIQDV  LVVSYLANTI  RTQIDLSNRL  300
301   ATAALTMGGG  DVLAGDDKKD  GDNNRGKGGD  RRGGGKGRQQ  RQQEA  345
Nucleotide CDS Sequence (FASTA)
1     ATGGCCGCCA  CCGACTCTTT  CCTCCATCTC  GCCCGCCCCC  TTGGCCCAGC  TCCGCTCGGT  60
61    GCTCAGCCAT  CGACTGCCCC  GCTGAACGTC  GCCATCCAAC  CCCAGGCCGT  CTTTTCTATC  120
121   CTCGATCACT  CACTCCGCCG  CCCCGCCGAC  CAAGAACGTG  TCATTGGTAC  CCTGCTCGGC  180
181   ACCCGCAGCG  AAGACGGCAC  TGAAATCGAG  ATCCGCAACT  GCTATGCTGT  CCCCCACACC  240
241   GAGACGGCCG  AGCAGGTCGA  GGTCGACATG  GACTACCAGA  AGTCGATGCT  AGCCCTTCAC  300
301   CTTCGCGCGA  ACCCCCGTGA  AGTCCTCGTT  GGCTGGTATG  CGACCAGCAG  CGACCTCAAC  360
361   ACCTTCTCCG  CCCTCATCCA  GAACTTTTAC  AGCCAGCAAG  GCGACGGAAC  ATGGCCACAC  420
421   CCCGCAGTCC  ATCTGACTGT  TTCCACAGTA  CCAGGACAAG  ACATCGAGTC  CAAGACATAC  480
481   ATTTCCGCGC  CCATTGGTGT  TACTGCTGAG  CGCGCTGCTG  ATTCTTGCTT  ATTCATCCCG  540
541   GTTCCCCACG  AGATCAAGTA  CGGCGAGGCA  GAGAGGTCAG  GACTGGAGCT  CATTTCATCC  600
601   GCAAAGGACC  GTGAGGACCG  ATCACAAGAG  GTCATGACCG  ACCTCGACTC  GCTTGAGCGC  660
661   GCAATCCAGC  ACGTACTTGA  CATGCTCGAG  CGCGTGTCCA  ACTACGTTAA  CAACGTTTTG  720
721   GACGAAGAGG  CGGAGCCATC  GTCAGCACTA  GGTCAATTTT  TGATGAATGC  ACTCAGCTTG  780
781   GCACCCAAGG  TTGAGCCCGC  GGATATTGAG  CGCGACTTCA  ACGCACACAT  TCAGGACGTT  840
841   CTCGTGGTAT  CATACCTCGC  CAACACTATT  CGCACCCAAA  TTGACCTCTC  AAATCGCCTT  900
901   GCTACTGCAG  CACTTACTAT  GGGCGGCGGT  GACGTTCTCG  CTGGTGACGA  CAAGAAGGAC  960
961   GGTGACAACA  ACAGGGGGAA  GGGCGGTGAC  CGACGAGGAG  GCGGCAAGGG  CAGGCAGCAA  1020
1021  AGGCAGCAAG  AGGCATGA  1038

▼ KEYWORD


ID
Family
Complete proteome
Cytoplasm
Initiation factor
Protein biosynthesis
Reference proteome

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Eukaryotic 43S preinitiation complex
Cellular Component
Eukaryotic 48S preinitiation complex
Cellular Component
Eukaryotic translation initiation factor 3 complex
Molecular Function
Translation initiation factor activity
Biological Process
Formation of cytoplasmic translation initiation complex

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pyt-0903Pyrenophora teres99.360.0 641
LLPS-Phn-1085Phaeosphaeria nodorum95.860.0 624
LLPS-Lem-0140Leptosphaeria maculans94.890.0 617
LLPS-Dos-1220Dothistroma septosporum82.470.0 534
LLPS-Zyt-0239Zymoseptoria tritici79.610.0 525
LLPS-Nef-0375Neosartorya fischeri78.960.0 519
LLPS-Asfu-0455Aspergillus fumigatus78.960.0 520
LLPS-Asn-0401Aspergillus nidulans78.960.0 517
LLPS-Asc-1224Aspergillus clavatus78.183e-179 508
LLPS-Ast-1167Aspergillus terreus77.671e-174 496
LLPS-Asni-0873Aspergillus niger76.872e-175 499
LLPS-Aso-0926Aspergillus oryzae76.72e-178 506
LLPS-Asf-0394Aspergillus flavus76.71e-178 506
LLPS-Tum-0670Tuber melanosporum69.282e-154 444
LLPS-Blg-0053Blumeria graminis68.143e-160 460
LLPS-Cogr-0846Colletotrichum graminicola63.697e-145 421
LLPS-Coo-0665Colletotrichum orbiculare63.382e-143 417
LLPS-Beb-0717Beauveria bassiana63.316e-141 411
LLPS-Fus-1333Fusarium solani63.314e-143 416
LLPS-Trr-0951Trichoderma reesei62.991e-140 410
LLPS-Trv-0652Trichoderma virens62.994e-140 409
LLPS-Fuo-0677Fusarium oxysporum62.991e-141 412
LLPS-Cog-0696Colletotrichum gloeosporioides62.422e-139 406
LLPS-Fuv-1519Fusarium verticillioides62.344e-140 409
LLPS-Ved-0000Verticillium dahliae61.091e-138 405
LLPS-Nec-0202Neurospora crassa60.581e-130 385
LLPS-Mao-1408Magnaporthe oryzae59.153e-127 377
LLPS-Gag-1316Gaeumannomyces graminis59.027e-128 378
LLPS-Scc-0839Schizosaccharomyces cryophilus52.683e-106 321
LLPS-Scj-1104Schizosaccharomyces japonicus52.677e-107 322
LLPS-Scp-0808Schizosaccharomyces pombe51.971e-108 326
LLPS-Yal-1063Yarrowia lipolytica47.337e-90 278
LLPS-Usm-0455Ustilago maydis47.222e-75 241
LLPS-Spr-1411Sporisorium reilianum46.531e-74 239
LLPS-Mel-0430Melampsora laricipopulina41.034e-62 207
LLPS-Abg-0577Absidia glauca38.952e-75 241
LLPS-Sem-1330Selaginella moellendorffii38.573e-59 199
LLPS-Prp-0441Prunus persica37.962e-54 186
LLPS-Php-2181Physcomitrella patens37.734e-52 180
LLPS-Coc-1984Corchorus capsularis37.684e-54 186
LLPS-Gor-0932Gossypium raimondii37.411e-49 174
LLPS-Brn-1175Brassica napus37.151e-46 166
LLPS-Xet-0310Xenopus tropicalis37.133e-52 181
LLPS-Amt-1910Amborella trichopoda37.115e-46 164
LLPS-Thc-1616Theobroma cacao36.974e-50 175
LLPS-Brr-2241Brassica rapa36.927e-46 164
LLPS-Bro-1196Brassica oleracea36.927e-47 167
LLPS-Dac-0639Daucus carota36.754e-53 183
LLPS-Via-0199Vigna angularis36.738e-49 171
LLPS-Mae-1522Manihot esculenta36.691e-46 166
LLPS-Cii-1555Ciona intestinalis36.333e-53 184
LLPS-Orl-2097Oryzias latipes36.267e-52 179
LLPS-Met-0942Medicago truncatula36.235e-52 180
LLPS-Glm-1001Glycine max36.23e-49 172
LLPS-Pot-1234Populus trichocarpa36.148e-53 182
LLPS-Fia-3328Ficedula albicollis36.032e-51 178
LLPS-Phv-2317Phaseolus vulgaris36.07e-48 169
LLPS-Vir-0783Vigna radiata36.06e-48 169
LLPS-Aon-0887Aotus nancymaae35.961e-47 171
LLPS-Dar-3907Danio rerio35.93e-51 178
LLPS-Orn-2166Oreochromis niloticus35.91e-51 178
LLPS-Scm-1430Scophthalmus maximus35.879e-50 174
LLPS-Sah-0100Sarcophilus harrisii35.858e-48 171
LLPS-Cus-0847Cucumis sativus35.824e-53 183
LLPS-Arl-1846Arabidopsis lyrata35.792e-46 166
LLPS-Pug-1397Puccinia graminis35.743e-55 189
LLPS-Mua-1325Musa acuminata35.744e-52 180
LLPS-Tra-0597Triticum aestivum35.744e-53 183
LLPS-Hov-0768Hordeum vulgare35.592e-53 184
LLPS-Otg-2622Otolemur garnettii35.541e-47 171
LLPS-Bot-1902Bos taurus35.542e-47 170
LLPS-Ova-1132Ovis aries35.545e-48 170
LLPS-Loa-1761Loxodonta africana35.538e-47 168
LLPS-Ten-0249Tetraodon nigroviridis35.537e-52 179
LLPS-Xim-0391Xiphophorus maculatus35.532e-49 173
LLPS-Cea-0879Cercocebus atys35.485e-43 158
LLPS-Mod-0760Monodelphis domestica35.42e-48 172
LLPS-Miv-0615Microbotryum violaceum35.41e-52 182
LLPS-Viv-2324Vitis vinifera35.347e-51 177
LLPS-Urm-1055Ursus maritimus35.191e-47 170
LLPS-Scf-0548Scleropages formosus35.162e-50 176
LLPS-Pof-1558Poecilia formosa35.094e-50 175
LLPS-Ora-1971Ornithorhynchus anatinus35.025e-43 155
LLPS-Tag-0380Taeniopygia guttata35.02e-43 155
LLPS-Fec-2330Felis catus34.971e-47 171
LLPS-Caf-3915Canis familiaris34.971e-47 170
LLPS-Aim-3318Ailuropoda melanoleuca34.972e-47 170
LLPS-Mup-3444Mustela putorius furo34.977e-48 170
LLPS-Pat-1960Pan troglodytes34.959e-48 171
LLPS-Pap-1309Pan paniscus34.959e-48 171
LLPS-Hos-1851Homo sapiens34.951e-47 171
LLPS-Orc-1456Oryctolagus cuniculus34.956e-48 171
LLPS-Rhb-2089Rhinopithecus bieti34.951e-47 170
LLPS-Mam-1847Macaca mulatta34.951e-47 171
LLPS-Poa-0770Pongo abelii34.951e-47 171
LLPS-Ict-3817Ictidomys tridecemlineatus34.951e-47 170
LLPS-Nol-2225Nomascus leucogenys34.952e-47 170
LLPS-Cas-1364Carlito syrichta34.955e-48 171
LLPS-Maf-2815Macaca fascicularis34.951e-47 171
LLPS-Chs-3521Chlorocebus sabaeus34.959e-48 171
LLPS-Caj-2668Callithrix jacchus34.951e-47 171
LLPS-Gog-2989Gorilla gorilla34.958e-48 171
LLPS-Paa-1442Papio anubis34.959e-48 171
LLPS-Mal-3049Mandrillus leucophaeus34.951e-47 171
LLPS-Ran-3980Rattus norvegicus34.951e-47 171
LLPS-Cis-0751Ciona savignyi34.891e-49 174
LLPS-Hea-0304Helianthus annuus34.864e-47 167
LLPS-Mum-3643Mus musculus34.842e-47 170
LLPS-Tut-0516Tursiops truncatus34.848e-48 171
LLPS-Myl-3634Myotis lucifugus34.812e-47 170
LLPS-Orbr-1742Oryza brachyantha34.86e-54 185
LLPS-Art-2197Arabidopsis thaliana34.742e-45 163
LLPS-Chr-1400Chlamydomonas reinhardtii34.711e-51 179
LLPS-Meg-2899Meleagris gallopavo34.64e-44 157
LLPS-Asm-3197Astyanax mexicanus34.562e-49 173
LLPS-Tar-1414Takifugu rubripes34.553e-51 180
LLPS-Nia-0320Nicotiana attenuata34.492e-45 162
LLPS-Orp-1637Oryza punctata34.468e-52 179
LLPS-Pes-3583Pelodiscus sinensis34.344e-44 160
LLPS-Sot-1229Solanum tuberosum34.282e-46 165
LLPS-Mea-0127Mesocricetus auratus34.232e-35 137
LLPS-Anp-1837Anas platyrhynchos34.212e-40 147
LLPS-Anc-3437Anolis carolinensis34.192e-47 169
LLPS-Icp-1980Ictalurus punctatus34.192e-48 170
LLPS-Lac-0311Latimeria chalumnae33.962e-27 112
LLPS-Sob-0710Sorghum bicolor33.947e-50 174
LLPS-Lep-0181Leersia perrieri33.921e-49 174
LLPS-Ors-0752Oryza sativa33.919e-51 177
LLPS-Orm-1054Oryza meridionalis33.914e-51 177
LLPS-Orr-0118Oryza rufipogon33.919e-51 177
LLPS-Org-0499Oryza glaberrima33.919e-51 177
LLPS-Orb-0260Oryza barthii33.919e-51 177
LLPS-Ori-1703Oryza indica33.919e-51 177
LLPS-Orni-0722Oryza nivara33.912e-51 178
LLPS-Orgl-1601Oryza glumaepatula33.919e-51 177
LLPS-Man-1783Macaca nemestrina33.92e-46 168
LLPS-Crn-0617Cryptococcus neoformans33.663e-49 173
LLPS-Sei-0458Setaria italica33.586e-49 172
LLPS-Gaga-0978Gallus gallus33.499e-34 129
LLPS-Chc-0384Chondrus crispus33.451e-41 153
LLPS-Gaa-0518Gasterosteus aculeatus33.225e-50 175
LLPS-Brd-0668Brachypodium distachyon33.213e-44 160
LLPS-Gas-0475Galdieria sulphuraria32.981e-38 144
LLPS-Zem-1458Zea mays32.851e-47 169
LLPS-Sol-1684Solanum lycopersicum32.512e-45 162
LLPS-Cap-0548Cavia porcellus32.44e-33 130
LLPS-Sus-2536Sus scrofa31.941e-40 151
LLPS-Eqc-0728Equus caballus31.82e-25 109
LLPS-Leo-1199Lepisosteus oculatus31.524e-33 130
LLPS-Tru-0786Triticum urartu31.482e-38 144
LLPS-Drm-0685Drosophila melanogaster31.183e-41 151
LLPS-Kop-0707Komagataella pastoris28.668e-44 159
LLPS-Put-1308Puccinia triticina28.321e-29 121
LLPS-Osl-0487Ostreococcus lucimarinus28.211e-25 108
LLPS-Cae-0006Caenorhabditis elegans25.683e-27 113
LLPS-Cym-0955Cyanidioschyzon merolae25.168e-1269.7