LLPS-Put-1100
EFM7
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Protein N-terminal and lysine N-methyltransferase EFM7; Elongation factor methyltransferase 7 |
| Gene Name: | EFM7, PTTG_02438 |
| Ensembl Gene: | PTTG_02438 |
| Ensembl Protein: | PTTG_02438P0 |
| Organism: | Puccinia triticina |
| Taxa ID: | 630390 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono-and dimethylation of 'Lys-3'. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | PTTG_02438T0 | PTTG_02438P0 |
| UniProt | A0A180H1W0, A0A180H1W0_PUCT1 | |
| GeneBank | ADAS02000004 | OAV99017.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MKNEALANED SDNADLPLPT DLFQEPSSFR PPSPEPKIIE HTTSDGTSLK IRLVGAHPLW 60 61 GHVLYPASII LSRYIQEHSK QLFPDHVSTN VLELGAGGGL PGLTCVLAGA SLGLKWGAKL 120 121 EDKIFEDATT PSASDTPSSQ HGFDLILLSD LVFNHSEHHA LLTTCEISLN STAPTSDRPT 180 181 PSLLVFYSHH RPWCVAADEE FFVIARQRGW KCTRIIEDKN AGLAFPADAG DPSIRGTVHG 240 241 WVLTRH 246 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAAAAACG AAGCGCTGGC GAACGAAGAT TCAGACAACG CCGATCTGCC ATTGCCAACT 60 61 GATCTCTTTC AGGAACCGAG CTCTTTCCGC CCACCGTCAC CAGAGCCGAA AATAATCGAA 120 121 CATACCACCT CCGACGGAAC CTCGTTAAAA ATCAGACTCG TCGGTGCTCA TCCGCTATGG 180 181 GGCCATGTGT TATATCCAGC TTCGATAATT TTATCACGTT ACATTCAAGA GCACTCCAAG 240 241 CAATTATTTC CCGACCACGT GTCCACCAAT GTTCTTGAGC TGGGTGCTGG AGGGGGATTA 300 301 CCCGGTCTAA CATGTGTTTT AGCCGGCGCA AGTTTGGGAC TCAAATGGGG AGCGAAGCTT 360 361 GAGGACAAGA TCTTCGAGGA CGCCACAACT CCAAGTGCTT CTGATACTCC ATCCTCCCAA 420 421 CACGGTTTCG ATTTGATATT GCTCTCAGAT TTAGTCTTCA ACCACTCAGA ACATCACGCT 480 481 CTCCTGACCA CGTGTGAGAT CAGTCTAAAC TCCACAGCCC CAACCAGCGA TCGTCCGACA 540 541 CCCTCTCTCC TAGTGTTTTA CTCTCATCAT CGACCTTGGT GTGTTGCAGC CGACGAAGAA 600 601 TTCTTCGTCA TCGCTCGTCA AAGGGGATGG AAGTGCACCC GAATCATCGA AGACAAGAAT 660 661 GCCGGTCTTG CATTTCCAGC AGATGCTGGT GATCCAAGTA TTAGAGGGAC AGTCCACGGC 720 721 TGGGTACTGA CTCGCCAT 738 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Molecular Function | N-terminal protein N-methyltransferase activity | |
Molecular Function | Protein-lysine N-methyltransferase activity | |
Biological Process | N-terminal peptidyl-glycine methylation | |
Biological Process | Peptidyl-lysine dimethylation |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Pug-1269 | Puccinia graminis | 78.26 | 2e-36 | 132 |
| LLPS-Mel-0671 | Melampsora laricipopulina | 62.14 | 6e-38 | 139 |
| LLPS-Miv-1495 | Microbotryum violaceum | 54.76 | 3e-07 | 54.7 |
| LLPS-Crn-1004 | Cryptococcus neoformans | 39.04 | 2e-25 | 106 |
| LLPS-Cym-1003 | Cyanidioschyzon merolae | 36.27 | 5e-07 | 53.5 |
| LLPS-Fus-0069 | Fusarium solani | 35.64 | 3e-13 | 72.8 |
| LLPS-Cogr-0663 | Colletotrichum graminicola | 35.35 | 5e-10 | 62.4 |
| LLPS-Scj-1577 | Schizosaccharomyces japonicus | 35.29 | 1e-23 | 100 |
| LLPS-Zyt-1430 | Zymoseptoria tritici | 33.86 | 3e-23 | 99.8 |
| LLPS-Ved-0878 | Verticillium dahliae | 33.66 | 3e-12 | 67.8 |
| LLPS-Tum-0227 | Tuber melanosporum | 33.58 | 2e-22 | 97.4 |
| LLPS-Lem-1521 | Leptosphaeria maculans | 33.46 | 5e-22 | 96.3 |
| LLPS-Usm-1478 | Ustilago maydis | 33.06 | 2e-22 | 101 |
| LLPS-Phn-1177 | Phaeosphaeria nodorum | 32.95 | 7e-23 | 98.6 |
| LLPS-Dos-0961 | Dothistroma septosporum | 32.94 | 7e-25 | 104 |
| LLPS-Pytr-0884 | Pyrenophora triticirepentis | 32.56 | 9e-25 | 103 |
| LLPS-Beb-0389 | Beauveria bassiana | 32.35 | 4e-11 | 65.1 |
| LLPS-Scp-0337 | Schizosaccharomyces pombe | 32.31 | 2e-22 | 97.4 |
| LLPS-Spr-0534 | Sporisorium reilianum | 32.23 | 7e-23 | 103 |
| LLPS-Gag-1553 | Gaeumannomyces graminis | 32.0 | 4e-13 | 70.9 |
| LLPS-Gas-1305 | Galdieria sulphuraria | 31.82 | 2e-13 | 71.2 |
| LLPS-Mao-1164 | Magnaporthe oryzae | 31.73 | 6e-14 | 73.2 |
| LLPS-Fuv-0461 | Fusarium verticillioides | 31.73 | 6e-11 | 64.3 |
| LLPS-Fuo-1554 | Fusarium oxysporum | 31.73 | 3e-11 | 65.5 |
| LLPS-Pyt-0712 | Pyrenophora teres | 31.4 | 5e-23 | 99.0 |
| LLPS-Map-1265 | Magnaporthe poae | 30.61 | 2e-11 | 65.9 |
| LLPS-Coo-1416 | Colletotrichum orbiculare | 30.04 | 2e-12 | 68.9 |
| LLPS-Asg-0882 | Ashbya gossypii | 30.04 | 7e-19 | 87.4 |
| LLPS-Abg-0028 | Absidia glauca | 29.8 | 4e-19 | 88.2 |
| LLPS-Asn-1118 | Aspergillus nidulans | 29.77 | 2e-12 | 68.6 |
| LLPS-Sac-0229 | Saccharomyces cerevisiae | 29.58 | 2e-15 | 77.0 |
| LLPS-Blg-1483 | Blumeria graminis | 29.1 | 9e-22 | 95.9 |
| LLPS-Trv-0185 | Trichoderma virens | 28.79 | 2e-12 | 70.5 |
| LLPS-Trr-0812 | Trichoderma reesei | 28.03 | 3e-11 | 67.0 |
| LLPS-Cog-1314 | Colletotrichum gloeosporioides | 26.98 | 8e-13 | 69.7 |
| LLPS-Aso-0902 | Aspergillus oryzae | 26.48 | 4e-19 | 87.8 |
| LLPS-Nec-1277 | Neurospora crassa | 26.16 | 4e-18 | 85.9 |
| LLPS-Scc-1464 | Schizosaccharomyces cryophilus | 25.89 | 3e-17 | 82.4 |
| LLPS-Ast-0081 | Aspergillus terreus | 25.78 | 6e-18 | 84.3 |
| LLPS-Asfu-1630 | Aspergillus fumigatus | 25.21 | 2e-15 | 77.4 |
| LLPS-Asni-0032 | Aspergillus niger | 24.79 | 6e-17 | 81.6 |
| LLPS-Asc-1522 | Aspergillus clavatus | 24.79 | 4e-15 | 76.3 |