• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pot-2090
POPTR_0078s00220g

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Peptidyl-prolyl cis-trans isomerase
Gene Name: POPTR_0078s00220g, POPTR_T051300
Ensembl Gene: POPTR_T051300v3
Ensembl Protein: PNS23581
Organism: Populus trichocarpa
Taxa ID: 3694
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSNPKVFFDI  LIGKMKAGRI  VMELFADATP  KTAENFRALC  TGEKGIGNAG  KPLHYKGSTF  60
61    HRIIPNFMCQ  GGDFTRGNGT  GGESIYGAKF  ADENFKLKHT  GPGVLSMANS  GPNTNGSQFF  120
121   ICTENTSWLD  GKHVVFGKVV  DGYGVVQEME  KVGSNSGTTK  ETVIVEDCGQ  IIEN  174
Nucleotide CDS Sequence (FASTA)
1     ATGTCGAATC  CGAAGGTTTT  CTTTGACATT  CTAATTGGCA  AGATGAAAGC  AGGTAGGATT  60
61    GTGATGGAAC  TATTTGCTGA  TGCTACTCCG  AAAACTGCTG  AAAATTTCCG  TGCTCTATGC  120
121   ACCGGGGAGA  AAGGGATTGG  AAATGCTGGG  AAACCATTAC  ACTATAAGGG  TTCGACTTTC  180
181   CATCGCATAA  TCCCAAACTT  CATGTGTCAA  GGTGGGGATT  TTACTAGGGG  TAATGGAACT  240
241   GGAGGAGAAT  CAATCTATGG  CGCAAAGTTT  GCAGATGAGA  ACTTTAAGCT  GAAGCATACA  300
301   GGGCCTGGTG  TTTTATCAAT  GGCAAATTCT  GGACCGAACA  CTAATGGTTC  CCAATTCTTC  360
361   ATTTGCACTG  AGAATACCTC  ATGGCTTGAT  GGGAAACATG  TTGTTTTTGG  GAAAGTTGTA  420
421   GATGGCTATG  GCGTTGTTCA  GGAAATGGAG  AAGGTAGGGT  CCAATAGTGG  GACGACAAAG  480
481   GAAACTGTTA  TTGTTGAAGA  TTGTGGTCAA  ATAATAGAGA  ACTGA  525

▼ KEYWORD

ID
Family
Complete proteome
Isomerase
Reference proteome
Rotamase

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
Cyclosporin A binding
Molecular Function
Peptidyl-prolyl cis-trans isomerase activity
Molecular Function
Unfolded protein binding
Biological Process
Protein refolding

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Viv-1390Vitis vinifera87.362e-100 294
LLPS-Via-0507Vigna angularis87.135e-98 288
LLPS-Thc-1933Theobroma cacao86.782e-98 289
LLPS-Mae-0496Manihot esculenta86.784e-101 295
LLPS-Prp-0858Prunus persica86.553e-98 288
LLPS-Phv-1484Phaseolus vulgaris86.551e-98 289
LLPS-Gor-2430Gossypium raimondii86.211e-97 287
LLPS-Vir-1621Vigna radiata86.161e-88 263
LLPS-Met-0961Medicago truncatula85.962e-97 286
LLPS-Glm-1322Glycine max85.965e-97 285
LLPS-Hea-0861Helianthus annuus85.637e-98 289
LLPS-Brn-1987Brassica napus85.381e-96 285
LLPS-Brr-2861Brassica rapa85.381e-96 285
LLPS-Orbr-1585Oryza brachyantha84.623e-95 281
LLPS-Sob-0242Sorghum bicolor84.36e-97 285
LLPS-Arl-1587Arabidopsis lyrata84.211e-94 279
LLPS-Lep-1114Leersia perrieri83.728e-96 282
LLPS-Sei-0738Setaria italica83.632e-94 279
LLPS-Art-1557Arabidopsis thaliana83.637e-94 277
LLPS-Bro-0728Brassica oleracea83.044e-94 278
LLPS-Orp-1258Oryza punctata82.566e-95 280
LLPS-Coc-2310Corchorus capsularis82.085e-91 280
LLPS-Ori-1838Oryza indica81.983e-94 278
LLPS-Org-1037Oryza glaberrima81.983e-94 278
LLPS-Orr-0598Oryza rufipogon81.983e-94 278
LLPS-Ors-2228Oryza sativa81.983e-94 278
LLPS-Amt-0153Amborella trichopoda81.871e-90 269
LLPS-Orm-0700Oryza meridionalis81.612e-94 280
LLPS-Dac-0738Daucus carota81.56e-92 272
LLPS-Sot-1632Solanum tuberosum81.43e-87 260
LLPS-Nia-0336Nicotiana attenuata81.44e-89 265
LLPS-Brd-2400Brachypodium distachyon81.294e-92 273
LLPS-Orgl-2120Oryza glumaepatula81.038e-94 278
LLPS-Orb-1889Oryza barthii81.038e-94 278
LLPS-Sol-1948Solanum lycopersicum80.811e-86 259
LLPS-Mua-1143Musa acuminata80.678e-76 230
LLPS-Pyt-1006Pyrenophora teres77.782e-85 256
LLPS-Lem-1122Leptosphaeria maculans77.788e-77 234
LLPS-Pytr-1437Pyrenophora triticirepentis77.785e-86 257
LLPS-Tra-2672Triticum aestivum77.198e-89 265
LLPS-Hov-0184Hordeum vulgare77.192e-87 261
LLPS-Cus-0174Cucumis sativus76.611e-79 241
LLPS-Phn-0241Phaeosphaeria nodorum76.022e-83 250
LLPS-Zem-0978Zea mays76.022e-82 248
LLPS-Sem-0043Selaginella moellendorffii75.884e-83 250
LLPS-Php-0782Physcomitrella patens74.276e-77 235
LLPS-Chr-0628Chlamydomonas reinhardtii73.687e-80 241
LLPS-Orni-0174Oryza nivara73.685e-81 244
LLPS-Cae-1494Caenorhabditis elegans73.12e-78 238
LLPS-Icp-3019Ictalurus punctatus71.931e-74 228
LLPS-Tru-0936Triticum urartu71.267e-73 225
LLPS-Orn-2993Oreochromis niloticus70.761e-74 228
LLPS-Gas-1091Galdieria sulphuraria70.189e-70 215
LLPS-Tar-4021Takifugu rubripes70.187e-71 218
LLPS-Orl-0008Oryzias latipes70.183e-74 227
LLPS-Pes-3479Pelodiscus sinensis70.135e-63 198
LLPS-Drm-0238Drosophila melanogaster69.594e-71 219
LLPS-Cii-0915Ciona intestinalis69.593e-74 227
LLPS-Chc-0337Chondrus crispus68.453e-68 211
LLPS-Xim-0806Xiphophorus maculatus68.421e-70 218
LLPS-Mea-2413Mesocricetus auratus68.422e-69 214
LLPS-Eqc-0775Equus caballus68.423e-69 214
LLPS-Caf-4201Canis familiaris68.428e-70 216
LLPS-Scm-3921Scophthalmus maximus68.423e-71 219
LLPS-Pof-0486Poecilia formosa68.423e-72 221
LLPS-Paa-4430Papio anubis67.846e-69 213
LLPS-Gog-4580Gorilla gorilla67.846e-69 213
LLPS-Nol-3741Nomascus leucogenys67.846e-69 213
LLPS-Mod-0910Monodelphis domestica67.847e-70 216
LLPS-Fec-3385Felis catus67.843e-68 211
LLPS-Hos-2263Homo sapiens67.846e-69 213
LLPS-Pat-4900Pan troglodytes67.846e-69 213
LLPS-Pap-3143Pan paniscus67.846e-69 213
LLPS-Ran-3665Rattus norvegicus67.259e-69 213
LLPS-Cea-1721Cercocebus atys67.252e-67 209
LLPS-Mam-4083Macaca mulatta67.253e-67 209
LLPS-Cis-1775Ciona savignyi67.248e-71 219
LLPS-Asc-1392Aspergillus clavatus67.075e-64 201
LLPS-Mal-0143Mandrillus leucophaeus66.673e-67 209
LLPS-Caj-2259Callithrix jacchus66.674e-67 209
LLPS-Fud-2640Fukomys damarensis66.674e-67 209
LLPS-Maf-1568Macaca fascicularis66.675e-69 214
LLPS-Aon-3181Aotus nancymaae66.675e-67 208
LLPS-Xet-0495Xenopus tropicalis66.672e-69 216
LLPS-Cas-2248Carlito syrichta66.674e-65 204
LLPS-Poa-4007Pongo abelii66.679e-67 208
LLPS-Beb-1264Beauveria bassiana66.477e-69 213
LLPS-Asm-1134Astyanax mexicanus66.272e-63 200
LLPS-Ova-0943Ovis aries66.082e-65 204
LLPS-Chs-3358Chlorocebus sabaeus66.085e-64 201
LLPS-Orc-1035Oryctolagus cuniculus66.089e-66 205
LLPS-Bot-2597Bos taurus65.681e-67 212
LLPS-Gaa-1737Gasterosteus aculeatus65.686e-67 209
LLPS-Sus-0323Sus scrofa65.682e-68 214
LLPS-Cap-2191Cavia porcellus65.685e-67 210
LLPS-Dar-2471Danio rerio65.685e-63 199
LLPS-Loa-0617Loxodonta africana65.684e-67 210
LLPS-Rhb-4638Rhinopithecus bieti65.58e-66 206
LLPS-Ere-0294Erinaceus europaeus65.095e-67 210
LLPS-Mup-3399Mustela putorius furo65.094e-67 210
LLPS-Aim-0739Ailuropoda melanoleuca65.094e-67 210
LLPS-Dio-1191Dipodomys ordii65.094e-67 210
LLPS-Ora-0964Ornithorhynchus anatinus65.094e-66 207
LLPS-Mum-1199Mus musculus65.094e-67 210
LLPS-Gaga-0501Gallus gallus65.091e-66 209
LLPS-Tag-0742Taeniopygia guttata65.092e-66 208
LLPS-Ict-1390Ictidomys tridecemlineatus65.094e-67 210
LLPS-Ten-2505Tetraodon nigroviridis65.095e-68 212
LLPS-Lac-2284Latimeria chalumnae65.092e-67 211
LLPS-Man-0065Macaca nemestrina65.096e-67 210
LLPS-Osl-0984Ostreococcus lucimarinus64.911e-64 202
LLPS-Anc-0740Anolis carolinensis64.532e-66 208
LLPS-Otg-2285Otolemur garnettii64.53e-67 211
LLPS-Leo-3060Lepisosteus oculatus64.121e-63 202
LLPS-Scf-3256Scleropages formosus63.223e-64 202