• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pof-4156
MDH2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Malate dehydrogenase
Gene Name: MDH2
Ensembl Gene: ENSPFOG00000020864.1
Ensembl Protein: ENSPFOP00000020986.1
Organism: Poecilia formosa
Taxa ID: 48698
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MFSRAVRPTV  GLARSLSTSS  QNHAKVAVLG  ASGGIGQPLS  LLLKNSPLVS  QLSLYDIAHT  60
61    PGVAADLSHI  ETRAQVSGYI  GPDQLGAALK  GCEVVVIPAG  VPRKPGMTRD  DLFNTNATIV  120
121   ANLADACARN  CPEAMICIIA  NPVNSTIPIT  SEVMKKHGVY  NPNRVFGVTT  LDIVRANTFV  180
181   AELKGLDPAR  VNVPVIGGHA  GKTIIPLISQ  CTPKVEFPSD  QLTALTERIQ  EAGTEVVKAK  240
241   AGAGSATLSM  AYAGARFTFS  VLDAMNGKEG  VVECAFVRSE  ETECKYFSTP  LLLGKNGIEK  300
301   NLGLGKLSAF  EEKLVADAMG  ELKASIKKGE  DFVAKMK  337
Nucleotide CDS Sequence (FASTA)
1     ATGTTTTCCC  GTGCAGTGAG  ACCCACCGTC  GGCCTGGCTC  GGAGCCTGTC  CACCTCCTCG  60
61    CAGAACCACG  CCAAGGTGGC  GGTGCTGGGC  GCTTCTGGCG  GCATAGGCCA  GCCGCTCTCA  120
121   CTGCTGCTGA  AGAACAGCCC  CTTGGTGAGC  CAGCTCTCCC  TTTACGATAT  TGCCCACACG  180
181   CCCGGGGTGG  CCGCTGACCT  CAGCCACATC  GAGACCAGGG  CCCAGGTGAG  CGGCTACATA  240
241   GGCCCCGACC  AGCTGGGCGC  CGCTCTGAAG  GGCTGCGAAG  TGGTGGTTAT  CCCCGCCGGC  300
301   GTGCCGAGGA  AACCCGGTAT  GACCCGAGAC  GACTTGTTCA  ACACCAACGC  CACCATCGTA  360
361   GCTAACCTGG  CGGACGCTTG  CGCACGCAAC  TGCCCCGAGG  CCATGATCTG  CATCATTGCC  420
421   AACCCCGTGA  ACTCCACCAT  ACCCATTACG  TCGGAGGTGA  TGAAGAAGCA  CGGCGTGTAT  480
481   AACCCCAACA  GGGTGTTCGG  GGTCACCACC  TTGGACATTG  TCAGAGCCAA  CACGTTTGTG  540
541   GCGGAGCTCA  AAGGCTTGGA  CCCGGCTCGG  GTCAACGTCC  CGGTGATTGG  CGGTCACGCT  600
601   GGGAAGACCA  TTATCCCCCT  GATCTCCCAG  TGCACCCCTA  AGGTCGAGTT  TCCTTCCGAC  660
661   CAGCTCACCG  CCCTGACCGA  GAGGATCCAG  GAGGCCGGTA  CGGAGGTGGT  GAAAGCCAAG  720
721   GCGGGGGCGG  GGTCCGCCAC  CCTGTCCATG  GCGTACGCAG  GTGCCCGCTT  CACCTTTTCC  780
781   GTCCTGGACG  CCATGAACGG  GAAGGAGGGC  GTGGTCGAGT  GCGCCTTCGT  CAGATCTGAG  840
841   GAGACGGAGT  GCAAGTACTT  CTCCACGCCG  CTGCTGCTCG  GCAAGAATGG  CATCGAGAAG  900
901   AACCTGGGGC  TGGGCAAGCT  GTCTGCGTTT  GAGGAGAAGC  TGGTGGCCGA  CGCCATGGGG  960
961   GAGCTGAAGG  CTTCCATCAA  GAAGGGCGAG  GACTTTGTGG  CCAAGATGAA  GTAA  1014

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Xim-2821Xiphophorus maculatus99.410.0 682
LLPS-Orl-2179Oryzias latipes94.960.0 653
LLPS-Tar-3341Takifugu rubripes93.770.0 648
LLPS-Scm-3735Scophthalmus maximus92.394e-127 372
LLPS-Ten-1176Tetraodon nigroviridis92.280.0 639
LLPS-Orn-1375Oreochromis niloticus91.690.0 639
LLPS-Gaa-2898Gasterosteus aculeatus91.690.0 633
LLPS-Dar-3317Danio rerio91.10.0 631
LLPS-Scf-2258Scleropages formosus91.10.0 635
LLPS-Icp-4228Ictalurus punctatus90.80.0 632
LLPS-Asm-2216Astyanax mexicanus89.910.0 623
LLPS-Leo-2131Lepisosteus oculatus89.910.0 620
LLPS-Anc-2303Anolis carolinensis88.040.0 598
LLPS-Lac-2574Latimeria chalumnae87.830.0 614
LLPS-Anp-2634Anas platyrhynchos86.120.0 566
LLPS-Sah-0163Sarcophilus harrisii85.80.0 588
LLPS-Orc-1455Oryctolagus cuniculus85.580.0 575
LLPS-Mod-0140Monodelphis domestica85.50.0 589
LLPS-Maf-0525Macaca fascicularis85.090.0 569
LLPS-Mal-2078Mandrillus leucophaeus84.420.0 563
LLPS-Ict-0605Ictidomys tridecemlineatus84.320.0 588
LLPS-Pat-0527Pan troglodytes84.020.0 587
LLPS-Pap-1116Pan paniscus84.020.0 587
LLPS-Mea-0856Mesocricetus auratus84.020.0 584
LLPS-Myl-3573Myotis lucifugus84.020.0 588
LLPS-Fia-2533Ficedula albicollis83.850.0 558
LLPS-Rhb-3148Rhinopithecus bieti83.730.0 584
LLPS-Hos-1861Homo sapiens83.730.0 586
LLPS-Man-4587Macaca nemestrina83.730.0 585
LLPS-Cas-0605Carlito syrichta83.730.0 582
LLPS-Mam-2378Macaca mulatta83.730.0 585
LLPS-Gog-1616Gorilla gorilla83.730.0 585
LLPS-Fud-0703Fukomys damarensis83.730.0 583
LLPS-Cea-2471Cercocebus atys83.730.0 585
LLPS-Paa-0473Papio anubis83.730.0 585
LLPS-Meg-2179Meleagris gallopavo83.680.0 584
LLPS-Gaga-4056Gallus gallus83.680.0 584
LLPS-Ova-3466Ovis aries83.640.0 569
LLPS-Loa-1852Loxodonta africana83.430.0 583
LLPS-Xet-2472Xenopus tropicalis83.430.0 581
LLPS-Cap-2464Cavia porcellus83.430.0 579
LLPS-Caj-3417Callithrix jacchus83.430.0 585
LLPS-Chs-2758Chlorocebus sabaeus83.430.0 581
LLPS-Dio-1882Dipodomys ordii83.430.0 581
LLPS-Mum-3914Mus musculus83.140.0 580
LLPS-Bot-4698Bos taurus83.140.0 578
LLPS-Eqc-1621Equus caballus82.840.0 578
LLPS-Ran-3330Rattus norvegicus82.840.0 579
LLPS-Fec-3518Felis catus82.250.0 576
LLPS-Sus-2519Sus scrofa82.250.0 573
LLPS-Tag-2879Taeniopygia guttata81.470.0 557
LLPS-Nol-1618Nomascus leucogenys81.360.0 553
LLPS-Urm-0905Ursus maritimus81.070.0 570
LLPS-Aon-2061Aotus nancymaae81.070.0 567
LLPS-Aim-2059Ailuropoda melanoleuca81.070.0 570
LLPS-Mup-2269Mustela putorius furo80.950.0 559
LLPS-Caf-1291Canis familiaris80.770.0 568
LLPS-Otg-1347Otolemur garnettii79.290.0 532
LLPS-Poa-4106Pongo abelii75.740.0 515
LLPS-Ora-3271Ornithorhynchus anatinus73.441e-154 444
LLPS-Cii-1522Ciona intestinalis72.594e-168 479
LLPS-Dac-0969Daucus carota63.643e-139 405
LLPS-Php-2483Physcomitrella patens63.583e-129 383
LLPS-Glm-0254Glycine max62.342e-127 376
LLPS-Org-0681Oryza glaberrima61.591e-127 378
LLPS-Orm-1256Oryza meridionalis61.591e-126 375
LLPS-Orr-1476Oryza rufipogon61.595e-127 379
LLPS-Orni-1407Oryza nivara61.596e-127 380
LLPS-Orb-1602Oryza barthii61.591e-126 379
LLPS-Orgl-0343Oryza glumaepatula61.591e-126 376
LLPS-Arl-2350Arabidopsis lyrata61.563e-123 367
LLPS-Ori-1580Oryza indica61.519e-130 382
LLPS-Drm-0540Drosophila melanogaster61.443e-145 421
LLPS-Ors-0532Oryza sativa61.276e-127 376
LLPS-Art-1515Arabidopsis thaliana61.242e-122 365
LLPS-Abg-0766Absidia glauca61.113e-128 377
LLPS-Orbr-1851Oryza brachyantha61.024e-128 377
LLPS-Nia-1119Nicotiana attenuata60.882e-125 373
LLPS-Zem-2446Zea mays60.753e-127 377
LLPS-Amt-2136Amborella trichopoda60.664e-128 380
LLPS-Hov-1503Hordeum vulgare60.634e-125 374
LLPS-Cus-0309Cucumis sativus60.572e-124 374
LLPS-Gor-2724Gossypium raimondii60.512e-124 370
LLPS-Sob-2263Sorghum bicolor60.441e-123 368
LLPS-Viv-0299Vitis vinifera60.445e-125 372
LLPS-Orp-1187Oryza punctata60.442e-126 375
LLPS-Lep-1006Leersia perrieri60.441e-126 376
LLPS-Tra-1513Triticum aestivum60.326e-125 371
LLPS-Prp-0741Prunus persica60.252e-123 368
LLPS-Sol-2434Solanum lycopersicum60.257e-124 373
LLPS-Sot-0854Solanum tuberosum60.252e-126 375
LLPS-Phv-0732Phaseolus vulgaris60.192e-128 378
LLPS-Vir-1553Vigna radiata60.191e-127 376
LLPS-Via-1327Vigna angularis60.191e-127 376
LLPS-Nef-1080Neosartorya fischeri60.132e-122 363
LLPS-Mae-0898Manihot esculenta60.124e-130 382
LLPS-Brr-1173Brassica rapa60.121e-130 384
LLPS-Bro-0320Brassica oleracea60.127e-130 383
LLPS-Brn-2435Brassica napus60.122e-130 383
LLPS-Coc-2276Corchorus capsularis60.062e-124 370
LLPS-Osl-0651Ostreococcus lucimarinus60.08e-122 360
LLPS-Hea-1764Helianthus annuus60.01e-128 379
LLPS-Sei-1002Setaria italica60.01e-127 376
LLPS-Asfu-0092Aspergillus fumigatus59.819e-122 361
LLPS-Tru-2018Triticum urartu59.681e-123 368
LLPS-Cae-1276Caenorhabditis elegans59.632e-131 386
LLPS-Thc-1382Theobroma cacao59.621e-122 367
LLPS-Brd-1902Brachypodium distachyon59.54e-121 362
LLPS-Gag-0788Gaeumannomyces graminis59.381e-120 358
LLPS-Pot-2264Populus trichocarpa59.312e-123 368
LLPS-Asf-0997Aspergillus flavus59.241e-115 348
LLPS-Aso-0869Aspergillus oryzae59.245e-117 349
LLPS-Mua-1447Musa acuminata59.192e-125 371
LLPS-Asc-0173Aspergillus clavatus59.114e-117 349
LLPS-Map-1111Magnaporthe poae59.085e-121 359
LLPS-Chr-0767Chlamydomonas reinhardtii59.056e-119 354
LLPS-Sem-1790Selaginella moellendorffii58.844e-121 360
LLPS-Mao-0137Magnaporthe oryzae58.778e-122 361
LLPS-Ast-0577Aspergillus terreus58.18e-114 341
LLPS-Cog-0116Colletotrichum gloeosporioides57.622e-119 355
LLPS-Cogr-1627Colletotrichum graminicola57.491e-118 353
LLPS-Asni-1101Aspergillus niger57.462e-110 332
LLPS-Pyt-0555Pyrenophora teres57.145e-123 364
LLPS-Nec-1369Neurospora crassa56.925e-118 352
LLPS-Met-2172Medicago truncatula56.915e-124 367
LLPS-Coo-1355Colletotrichum orbiculare56.887e-119 353
LLPS-Pytr-1208Pyrenophora triticirepentis56.851e-122 363
LLPS-Trv-1364Trichoderma virens56.791e-115 345
LLPS-Lem-0848Leptosphaeria maculans56.754e-123 364
LLPS-Miv-1171Microbotryum violaceum56.53e-113 339
LLPS-Trr-1355Trichoderma reesei56.482e-115 345
LLPS-Fus-0519Fusarium solani56.441e-114 343
LLPS-Dos-1267Dothistroma septosporum56.354e-117 349
LLPS-Spr-1330Sporisorium reilianum56.214e-121 359
LLPS-Asn-1497Aspergillus nidulans56.181e-114 343
LLPS-Tum-1247Tuber melanosporum55.693e-118 352
LLPS-Usm-0268Ustilago maydis55.567e-121 359
LLPS-Zyt-0764Zymoseptoria tritici55.565e-120 357
LLPS-Crn-0385Cryptococcus neoformans55.491e-122 363
LLPS-Blg-1217Blumeria graminis55.217e-116 346
LLPS-Phn-0263Phaeosphaeria nodorum55.031e-121 360
LLPS-Put-0898Puccinia triticina54.747e-111 334
LLPS-Scs-0776Sclerotinia sclerotiorum54.748e-114 341
LLPS-Pug-0298Puccinia graminis54.012e-111 335
LLPS-Kop-0888Komagataella pastoris53.991e-111 335