• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pof-3303
YES1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Tyrosine-protein kinase
Gene Name: YES1
Ensembl Gene: ENSPFOG00000016976.2
Ensembl Protein: ENSPFOP00000017087.2
Organism: Poecilia formosa
Taxa ID: 48698
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granule, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGCVKSKENK  GPTMKYQTEN  SSRSDPSASA  AVPHVGHYGP  DPTQTQQNQA  PASSSSSAAL  60
61    NFNHALTPFG  GSSSAMTPFG  GASTSFSGPM  SNSFSGAVSS  GVTFFVALYD  YEARTSDDLT  120
121   FKKGDRFQII  NNTEGDWWEA  RSINTGKKGY  IPSNYVAPAD  SIQAEEWYFG  KMGRKDAERL  180
181   LLNPGNNRGT  FLVRESETTK  GAYSLSIRDW  DEAKGDNVKH  YKIRKLDNGG  YYITTRAQFD  240
241   TLPKLVKHYT  EHADGLCHKL  TTVCPTVKPQ  TQGLAKDAWE  IPRESLQLEV  KLGQGCFGEV  300
301   WMGTWNGTTK  VAIKTLKTGT  MSPEAFLQEA  QIMKKLRHDK  LVPLYAVVSE  EPIYIVTEYM  360
361   SKGSLLDFVK  EGDGKFLTLI  TLVDMAAKIA  DGMAFIERMN  YIHRDLRAAN  ILVGENLVCK  420
421   IADFGLARLI  EDNEYTARQG  AKFPIKWTAP  EAALYGRFTI  KSDVWSFGIL  LTELVTKGRV  480
481   PYPGMVNREV  LEQVERGYRM  PCPPGCPETL  HEMMMLCWKK  EPDERPTFEY  LQSFLEDYFT  540
541   STEPQYQPGE  NL  552
Nucleotide CDS Sequence (FASTA)
1     ATGGGCTGCG  TGAAGAGCAA  AGAAAACAAA  GGTCCCACCA  TGAAGTATCA  GACCGAGAAT  60
61    TCCTCACGGT  CTGACCCCAG  CGCCTCTGCC  GCCGTGCCTC  ACGTCGGCCA  CTACGGGCCA  120
121   GACCCGACGC  AGACGCAGCA  GAATCAGGCT  CCCGCGTCTT  CCTCCAGCTC  CGCAGCTCTG  180
181   AATTTCAACC  ACGCCCTCAC  TCCGTTCGGA  GGCTCCTCCT  CTGCCATGAC  TCCCTTTGGA  240
241   GGAGCGTCGA  CCTCCTTCTC  TGGTCCCATG  TCCAACTCCT  TCTCTGGTGC  CGTCTCTAGT  300
301   GGCGTCACCT  TCTTTGTTGC  CTTGTACGAC  TACGAAGCCA  GAACATCAGA  TGATCTTACG  360
361   TTTAAAAAGG  GGGATCGCTT  TCAGATCATC  AACAATACCG  AAGGAGACTG  GTGGGAGGCT  420
421   CGCTCCATTA  ACACCGGGAA  GAAGGGCTAC  ATCCCCAGCA  ATTATGTGGC  CCCCGCCGAC  480
481   TCCATTCAGG  CTGAAGAGTG  GTACTTTGGC  AAAATGGGGC  GCAAAGATGC  TGAGAGGCTG  540
541   CTGCTCAATC  CCGGGAATAA  TCGAGGGACT  TTCCTGGTGC  GGGAGAGTGA  AACAACTAAA  600
601   GGTGCTTATT  CTCTGTCCAT  ACGCGACTGG  GATGAAGCCA  AAGGAGACAA  CGTGAAGCAC  660
661   TACAAGATCC  GCAAGCTGGA  TAACGGGGGC  TACTACATCA  CCACGCGAGC  CCAGTTCGAC  720
721   ACGCTGCCGA  AGCTCGTCAA  ACACTACACA  GAGCACGCTG  ACGGACTCTG  CCACAAGCTG  780
781   ACCACGGTCT  GCCCCACGGT  CAAGCCTCAG  ACTCAGGGGC  TCGCTAAAGA  TGCCTGGGAG  840
841   ATCCCGAGGG  AGTCGCTGCA  GCTGGAGGTC  AAACTGGGCC  AGGGATGCTT  CGGAGAAGTG  900
901   TGGATGGGCA  CATGGAACGG  CACCACCAAA  GTGGCCATAA  AGACGCTGAA  GACGGGCACC  960
961   ATGTCGCCCG  AGGCCTTCCT  GCAGGAAGCT  CAGATCATGA  AGAAACTCAG  GCATGACAAA  1020
1021  CTAGTGCCTC  TTTATGCTGT  TGTGTCTGAG  GAGCCCATCT  ATATCGTCAC  AGAGTACATG  1080
1081  TCCAAAGGAA  GCTTGCTTGA  CTTCGTCAAA  GAAGGTGACG  GTAAATTCCT  GACGCTCATC  1140
1141  ACGCTGGTGG  ACATGGCCGC  AAAGATTGCA  GACGGGATGG  CTTTCATCGA  GCGGATGAAC  1200
1201  TACATTCACA  GAGATCTGCG  CGCCGCGAAC  ATACTCGTGG  GCGAGAACTT  GGTGTGTAAG  1260
1261  ATTGCCGACT  TCGGTCTGGC  CAGGCTGATA  GAAGACAACG  AGTACACAGC  CAGGCAAGGA  1320
1321  GCCAAATTCC  CAATCAAGTG  GACGGCCCCC  GAAGCCGCTC  TGTACGGTCG  CTTCACCATC  1380
1381  AAGTCAGACG  TCTGGTCCTT  CGGGATCCTC  CTCACCGAGC  TAGTTACCAA  AGGCAGGGTG  1440
1441  CCCTATCCAG  GTATGGTGAA  CCGGGAGGTG  CTGGAGCAGG  TGGAGCGGGG  TTACCGCATG  1500
1501  CCCTGCCCAC  CAGGTTGCCC  TGAGACCCTG  CATGAGATGA  TGATGCTCTG  CTGGAAGAAG  1560
1561  GAGCCGGATG  AGAGGCCCAC  CTTCGAGTAC  CTGCAGTCCT  TCTTGGAGGA  CTACTTCACC  1620
1621  TCCACAGAGC  CTCAGTATCA  GCCTGGAGAA  AACCTATAG  1659

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Xim-1298Xiphophorus maculatus98.730.01104
LLPS-Orl-3732Oryzias latipes91.670.01041
LLPS-Ora-1852Ornithorhynchus anatinus91.070.0 886
LLPS-Tar-3880Takifugu rubripes90.220.01027
LLPS-Poa-4321Pongo abelii90.140.0 908
LLPS-Ten-1376Tetraodon nigroviridis88.610.01004
LLPS-Asm-0258Astyanax mexicanus87.160.0 977
LLPS-Icp-1012Ictalurus punctatus86.330.0 970
LLPS-Dar-1703Danio rerio85.790.0 969
LLPS-Leo-1859Lepisosteus oculatus85.770.0 954
LLPS-Scf-4186Scleropages formosus85.570.0 814
LLPS-Scm-3870Scophthalmus maximus84.810.0 963
LLPS-Lac-3216Latimeria chalumnae84.630.0 956
LLPS-Orn-3725Oreochromis niloticus84.320.0 960
LLPS-Mup-3313Mustela putorius furo84.090.0 943
LLPS-Gaga-3471Gallus gallus84.090.0 956
LLPS-Meg-2822Meleagris gallopavo84.090.0 956
LLPS-Urm-2272Ursus maritimus84.090.0 945
LLPS-Aim-0676Ailuropoda melanoleuca83.940.0 941
LLPS-Bot-3448Bos taurus83.910.0 941
LLPS-Caf-1198Canis familiaris83.910.0 943
LLPS-Fec-2314Felis catus83.910.0 954
LLPS-Anp-0465Anas platyrhynchos83.910.0 954
LLPS-Gaa-3821Gasterosteus aculeatus83.810.0 948
LLPS-Tag-2197Taeniopygia guttata83.770.0 756
LLPS-Tut-1237Tursiops truncatus83.730.0 936
LLPS-Sus-2494Sus scrofa83.730.0 941
LLPS-Cas-0715Carlito syrichta83.730.0 938
LLPS-Anc-2636Anolis carolinensis83.730.0 946
LLPS-Orc-3500Oryctolagus cuniculus83.730.0 937
LLPS-Ova-3182Ovis aries83.70.0 936
LLPS-Mum-3176Mus musculus83.570.0 935
LLPS-Ran-3315Rattus norvegicus83.540.0 937
LLPS-Mal-4055Mandrillus leucophaeus83.540.0 937
LLPS-Paa-1551Papio anubis83.540.0 937
LLPS-Chs-1257Chlorocebus sabaeus83.540.0 937
LLPS-Maf-2709Macaca fascicularis83.540.0 936
LLPS-Cea-1899Cercocebus atys83.540.0 937
LLPS-Cap-3292Cavia porcellus83.540.0 934
LLPS-Eqc-2813Equus caballus83.540.0 937
LLPS-Mam-3787Macaca mulatta83.540.0 937
LLPS-Hos-2631Homo sapiens83.540.0 936
LLPS-Pap-3320Pan paniscus83.540.0 936
LLPS-Man-2101Macaca nemestrina83.540.0 936
LLPS-Fia-1709Ficedula albicollis83.540.0 957
LLPS-Pes-2183Pelodiscus sinensis83.450.0 951
LLPS-Mod-2646Monodelphis domestica83.360.0 940
LLPS-Caj-2837Callithrix jacchus83.180.0 932
LLPS-Fud-0859Fukomys damarensis83.180.0 931
LLPS-Myl-4036Myotis lucifugus83.090.0 933
LLPS-Mea-2833Mesocricetus auratus83.00.0 935
LLPS-Dio-2638Dipodomys ordii82.820.0 938
LLPS-Otg-1344Otolemur garnettii82.820.0 929
LLPS-Rhb-3895Rhinopithecus bieti82.680.0 798
LLPS-Loa-4436Loxodonta africana82.460.0 929
LLPS-Xet-0585Xenopus tropicalis81.040.0 937
LLPS-Gog-4632Gorilla gorilla80.810.0 922
LLPS-Pat-0346Pan troglodytes80.810.0 922
LLPS-Aon-3625Aotus nancymaae80.00.0 812
LLPS-Ict-4453Ictidomys tridecemlineatus80.00.0 813
LLPS-Sah-3984Sarcophilus harrisii79.380.0 820
LLPS-Ere-0346Erinaceus europaeus78.30.0 561
LLPS-Nol-2101Nomascus leucogenys78.120.0 782
LLPS-Cii-1366Ciona intestinalis71.210.0 684