LLPS-Pof-2190
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Neighbor of brca1 gene 1a |
| Ensembl Gene: | ENSPFOG00000017490.2 |
| Ensembl Protein: | ENSPFOP00000017635.2 |
| Organism: | Poecilia formosa |
| Taxa ID: | 48698 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Droplet | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPFOT00000017657.2 | ENSPFOP00000017635.2 |
| UniProt | A0A087YHY2, A0A087YHY2_POEFO | |
| GeneBank | AYCK01001231, AYCK01001232 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MGLPVTIKVN FRGNVKRFLA QDVDKLEWES VEAWIKASFG INHFQVKYFD EDNEEICINS 60 61 QDEYEEAIKS AEKQGNQLHM NVYKMKGQAC GGPLKAEVKE LKGDLRPAPP YPSRVKSVDK 120 121 GTQITPERES VAVKENKGNK PDDDPPPMWF RSYMEKFKDE VVKEVVERMC NDFSGQCCTH 180 181 KSSDGLQEDC GAIEGPIGPR PGPSTSNGSL GYTPNCSTCN KLTSEGAYKC SVCPSCILCE 240 241 MCRHSHDPSH SLVRTKTPLS IPEHGMSAST LLKVKTRQKM FPRRGDRTVR KAERQRLKAE 300 301 RRQLKAEVKE IKKKLRLEKR GMQWRSRHRP RSHPSPGPRP PGLQSRTMLC TLETRGPGVS 360 361 HTSLVPTMAA LFLDENLPDN TRLEPGTKFI KYWKMKNSGT ISWTSETKLV FMWGNLGLAS 420 421 EERREVPVPL LLPGQVGVVS VAFVAPVMEG MYTSHWRLAH CGCQFGPRVW CSIVVDSGSG 480 481 RNGLGHQSKR LAVCSTLCLM ECQGSEIALN SHKRRRLEAA APGYMILQKA WRSVASKQDF 540 541 YFPSVDLLTA QDLLSFELLD INIVQELEKV PNNTPVALTP CISPLPNDSS LLERTMTSQT 600 601 KDESETTGVR KLFGVKLRPK DVLEPVAQDE EKEEEISGAQ FLCETVIRSL TLEEAPDHRP 660 661 LRRAKHSSLK PQDPEFGAEN DNEDKEVLHT MQNMKEKNCE KEEGRTREDW DEVSSQTSSV 720 721 SSSDDYIIVL PDCFDTSRPL GESMYSSAMS QPDTAAASAT AASSTDPDQE QEKDEPCNFE 780 781 PCREAPLMES SVNQMLCASQ TLDAVTLTPE VVPPPVVPQP LHPTPTHVPH LYHPVCPDQP 840 841 AQHAVPLRRT IRERAKRCSQ GAKQQSKTSY ATISVLGQGG ITEGLVKGAL SVAASAYKAL 900 901 FTGPNCSIQG ILTLISELQD PSMMAVLLEM GFKDQQLNQQ LLRKHGYNLL HTVNELVQMA 960 961 EESQNE 966 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGGGCTCC CGGTCACGAT TAAAGTCAAT TTTCGCGGGA ATGTGAAGAG ATTCCTGGCT 60 61 CAGGATGTGG ACAAATTGGA GTGGGAGTCC GTGGAAGCCT GGATCAAAGC GTCATTTGGG 120 121 ATCAACCACT TTCAAGTTAA ATACTTTGAT GAAGATAATG AAGAGATCTG CATAAACAGT 180 181 CAAGATGAAT ACGAAGAAGC AATCAAGAGT GCAGAGAAGC AGGGGAACCA GCTGCACATG 240 241 AATGTGTACA AGATGAAGGG TCAGGCATGC GGCGGTCCTC TGAAGGCGGA GGTGAAGGAG 300 301 CTTAAAGGAG ACCTCCGACC TGCTCCGCCG TACCCGTCAA GAGTTAAATC CGTGGACAAA 360 361 GGCACTCAGA TCACCCCAGA GCGAGAAAGC GTAGCAGTAA AAGAAAACAA GGGGAATAAA 420 421 CCTGACGATG ATCCTCCTCC TATGTGGTTC AGATCGTACA TGGAGAAGTT TAAGGACGAA 480 481 GTCGTAAAGG AGGTGGTGGA ACGGATGTGC AACGACTTCT CCGGCCAGTG TTGCACTCAC 540 541 AAATCCTCCG ACGGGCTCCA AGAGGACTGT GGGGCCATTG AAGGACCTAT AGGGCCCCGA 600 601 CCGGGCCCCT CCACCTCTAA CGGATCGCTA GGGTACACCC CAAACTGCAG CACCTGCAAC 660 661 AAGCTCACCT CTGAGGGGGC TTACAAATGC AGTGTGTGCC CGTCCTGCAT CCTGTGTGAG 720 721 ATGTGCAGAC ACAGCCACGA TCCGAGCCAC AGCCTGGTGA GAACCAAGAC GCCTCTCTCC 780 781 ATCCCCGAGC ATGGAATGTC GGCATCTACA TTATTAAAGG TGAAGACAAG GCAAAAAATG 840 841 TTCCCAAGGC GAGGAGACAG GACTGTGCGC AAGGCCGAGA GACAGCGCCT CAAAGCTGAA 900 901 AGAAGGCAGC TGAAAGCAGA GGTGAAGGAA ATCAAGAAGA AACTGAGGCT GGAGAAGAGG 960 961 GGGATGCAGT GGAGGTCCCG CCACAGACCC AGGTCACATC CCAGCCCCGG TCCCCGACCC 1020 1021 CCAGGCCTCC AGTCCAGAAC AATGCTCTGT ACACTTGAAA CTAGGGGTCC CGGGGTCTCG 1080 1081 CACACGTCCT TGGTGCCCAC TATGGCTGCC TTGTTTCTGG ATGAAAATCT GCCTGATAAC 1140 1141 ACCCGTCTGG AGCCTGGTAC CAAGTTCATC AAATACTGGA AGATGAAGAA CTCGGGCACA 1200 1201 ATCAGCTGGA CTTCAGAGAC CAAGCTAGTG TTCATGTGGG GAAACCTCGG CTTGGCGTCG 1260 1261 GAGGAGAGGA GGGAGGTTCC AGTGCCCCTT CTGCTTCCGG GACAAGTGGG CGTGGTCAGT 1320 1321 GTGGCCTTTG TGGCTCCCGT CATGGAGGGG ATGTACACCT CCCACTGGCG GCTGGCGCAC 1380 1381 TGCGGCTGTC AGTTCGGCCC GCGGGTCTGG TGCAGCATTG TGGTCGACTC TGGCAGCGGC 1440 1441 CGCAACGGGC TCGGGCACCA AAGCAAGCGA TTGGCAGTGT GCTCCACATT GTGTTTGATG 1500 1501 GAGTGTCAGG GTTCAGAGAT TGCGTTGAAC TCGCACAAAA GGAGAAGACT GGAAGCAGCA 1560 1561 GCACCTGGAT ACATGATCCT TCAGAAAGCT TGGAGAAGTG TTGCATCAAA ACAAGACTTC 1620 1621 TACTTCCCAT CGGTCGACCT GCTGACCGCA CAGGATCTGC TTTCATTTGA GTTGCTGGAC 1680 1681 ATAAATATTG TGCAAGAGTT GGAAAAAGTC CCCAACAACA CTCCCGTTGC TTTGACTCCC 1740 1741 TGCATCTCTC CCCTCCCCAA TGATTCATCT TTGTTGGAAA GGACGATGAC TTCACAGACG 1800 1801 AAGGACGAGT CGGAGACCAC AGGAGTCCGC AAACTCTTCG GAGTCAAACT GAGGCCCAAA 1860 1861 GACGTGTTGG AGCCCGTAGC GCAAGACGAG GAGAAGGAGG AGGAGATCAG TGGAGCTCAG 1920 1921 TTCCTCTGCG AGACGGTGAT CCGCTCCCTC ACGCTGGAGG AGGCCCCGGA CCACAGGCCC 1980 1981 CTGCGCCGAG CCAAGCACAG CAGCCTCAAA CCGCAGGATC CTGAGTTCGG AGCCGAAAAT 2040 2041 GATAACGAAG ACAAAGAGGT TTTGCACACT ATGCAAAACA TGAAGGAGAA GAATTGCGAG 2100 2101 AAAGAAGAAG GCAGAACCAG AGAAGACTGG GATGAGGTCA GCAGCCAGAC GTCCTCCGTC 2160 2161 TCCTCCAGCG ACGACTACAT CATCGTCCTC CCAGACTGCT TCGACACCAG CCGGCCCCTG 2220 2221 GGCGAGTCCA TGTACAGCTC CGCCATGTCG CAGCCCGACA CCGCCGCCGC GAGCGCCACC 2280 2281 GCGGCCTCTT CGACCGACCC GGACCAAGAG CAGGAAAAGG ACGAGCCCTG CAACTTTGAG 2340 2341 CCGTGCAGGG AGGCGCCGCT GATGGAGAGC AGCGTGAACC AGATGCTGTG CGCGTCGCAA 2400 2401 ACGCTCGACG CCGTGACGCT CACGCCTGAA GTGGTGCCGC CGCCTGTCGT GCCTCAGCCC 2460 2461 CTGCACCCCA CACCGACTCA TGTTCCTCAT CTATATCATC CGGTCTGTCC AGATCAGCCG 2520 2521 GCTCAGCATG CAGTGCCTTT GAGGCGTACA ATCCGAGAGC GGGCAAAGCG CTGCAGCCAA 2580 2581 GGTGCAAAAC AGCAGAGTAA AACTTCTTAT GCTACAATTT CTGTGCTGGG CCAAGGAGGC 2640 2641 ATCACAGAGG GACTTGTCAA AGGGGCCCTT TCTGTGGCCG CATCTGCTTA TAAGGCTCTC 2700 2701 TTCACTGGAC CAAACTGTTC CATACAGGGA ATCCTGACTT TAATCTCAGA ATTACAGGAC 2760 2761 CCTTCCATGA TGGCCGTGCT GCTGGAGATG GGCTTTAAGG ACCAGCAGCT CAACCAGCAG 2820 2821 CTGCTGAGGA AGCACGGCTA CAACCTGCTG CACACCGTCA ACGAGCTGGT CCAGATGGCC 2880 2881 GAGGAAAGCC AGAATGAA 2898 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Xim-1559 | Xiphophorus maculatus | 82.06 | 0.0 | 1034 |
| LLPS-Leo-0586 | Lepisosteus oculatus | 65.48 | 3e-20 | 101 |
| LLPS-Dar-3839 | Danio rerio | 65.06 | 1e-20 | 102 |
| LLPS-Scm-2228 | Scophthalmus maximus | 64.48 | 0.0 | 1058 |
| LLPS-Tar-0701 | Takifugu rubripes | 61.9 | 8e-18 | 93.2 |
| LLPS-Scf-4103 | Scleropages formosus | 60.0 | 3e-21 | 103 |
| LLPS-Ora-2219 | Ornithorhynchus anatinus | 52.5 | 2e-08 | 62.8 |
| LLPS-Anp-2360 | Anas platyrhynchos | 51.19 | 2e-12 | 75.9 |
| LLPS-Urm-2895 | Ursus maritimus | 50.96 | 1e-17 | 92.4 |
| LLPS-Asm-0862 | Astyanax mexicanus | 50.73 | 0.0 | 767 |
| LLPS-Tag-2422 | Taeniopygia guttata | 50.52 | 3e-13 | 78.6 |
| LLPS-Aon-1375 | Aotus nancymaae | 50.0 | 2e-13 | 79.0 |
| LLPS-Icp-3324 | Ictalurus punctatus | 49.35 | 2e-155 | 491 |
| LLPS-Orn-1887 | Oreochromis niloticus | 46.88 | 0.0 | 602 |
| LLPS-Gaa-0103 | Gasterosteus aculeatus | 46.83 | 0.0 | 581 |
| LLPS-Orl-2908 | Oryzias latipes | 46.1 | 7e-158 | 494 |
| LLPS-Ten-2294 | Tetraodon nigroviridis | 45.97 | 0.0 | 614 |
| LLPS-Fia-2458 | Ficedula albicollis | 45.74 | 3e-11 | 72.0 |
| LLPS-Rhb-2146 | Rhinopithecus bieti | 43.02 | 3e-125 | 409 |
| LLPS-Anc-3497 | Anolis carolinensis | 42.9 | 8e-125 | 410 |
| LLPS-Caj-1468 | Callithrix jacchus | 42.12 | 5e-173 | 539 |
| LLPS-Hos-1879 | Homo sapiens | 41.69 | 2e-166 | 520 |
| LLPS-Eqc-2994 | Equus caballus | 41.67 | 9e-166 | 518 |
| LLPS-Cas-2380 | Carlito syrichta | 41.57 | 2e-167 | 522 |
| LLPS-Chs-1898 | Chlorocebus sabaeus | 41.29 | 7e-171 | 531 |
| LLPS-Orc-4177 | Oryctolagus cuniculus | 41.24 | 1e-169 | 528 |
| LLPS-Myl-3311 | Myotis lucifugus | 41.24 | 1e-167 | 523 |
| LLPS-Mup-4451 | Mustela putorius furo | 41.14 | 1e-167 | 522 |
| LLPS-Nol-2584 | Nomascus leucogenys | 41.13 | 1e-166 | 520 |
| LLPS-Bot-4671 | Bos taurus | 41.01 | 1e-166 | 521 |
| LLPS-Sot-1961 | Solanum tuberosum | 40.95 | 2e-09 | 65.5 |
| LLPS-Sol-0693 | Solanum lycopersicum | 40.95 | 3e-08 | 62.0 |
| LLPS-Caf-2786 | Canis familiaris | 40.94 | 1e-164 | 514 |
| LLPS-Poa-2382 | Pongo abelii | 40.9 | 9e-170 | 528 |
| LLPS-Pap-4262 | Pan paniscus | 40.9 | 3e-158 | 499 |
| LLPS-Ict-4214 | Ictidomys tridecemlineatus | 40.89 | 2e-162 | 509 |
| LLPS-Lac-2781 | Latimeria chalumnae | 40.82 | 4e-174 | 541 |
| LLPS-Ova-2562 | Ovis aries | 40.8 | 6e-164 | 514 |
| LLPS-Sus-3985 | Sus scrofa | 40.78 | 2e-155 | 492 |
| LLPS-Tut-1842 | Tursiops truncatus | 40.74 | 7e-69 | 243 |
| LLPS-Mod-0859 | Monodelphis domestica | 40.72 | 5e-165 | 517 |
| LLPS-Pat-2910 | Pan troglodytes | 40.69 | 2e-156 | 494 |
| LLPS-Fec-0191 | Felis catus | 40.69 | 9e-165 | 515 |
| LLPS-Gog-4267 | Gorilla gorilla | 40.69 | 9e-157 | 495 |
| LLPS-Paa-2911 | Papio anubis | 40.58 | 2e-163 | 512 |
| LLPS-Aim-2500 | Ailuropoda melanoleuca | 40.54 | 3e-165 | 517 |
| LLPS-Mal-1096 | Mandrillus leucophaeus | 40.42 | 1e-162 | 510 |
| LLPS-Mam-0479 | Macaca mulatta | 40.36 | 8e-165 | 516 |
| LLPS-Maf-0846 | Macaca fascicularis | 40.36 | 1e-164 | 516 |
| LLPS-Otg-1252 | Otolemur garnettii | 40.12 | 8e-165 | 516 |
| LLPS-Cea-4689 | Cercocebus atys | 40.12 | 7e-151 | 479 |
| LLPS-Man-4558 | Macaca nemestrina | 40.02 | 1e-159 | 501 |
| LLPS-Mum-4846 | Mus musculus | 39.78 | 9e-156 | 492 |
| LLPS-Ran-3781 | Rattus norvegicus | 39.7 | 2e-160 | 504 |
| LLPS-Loa-3845 | Loxodonta africana | 39.58 | 4e-164 | 514 |
| LLPS-Cap-2804 | Cavia porcellus | 39.57 | 5e-153 | 485 |
| LLPS-Sah-0862 | Sarcophilus harrisii | 39.38 | 1e-169 | 530 |
| LLPS-Meg-0521 | Meleagris gallopavo | 39.07 | 5e-161 | 505 |
| LLPS-Pes-2637 | Pelodiscus sinensis | 38.7 | 9e-161 | 506 |
| LLPS-Gaga-3679 | Gallus gallus | 38.66 | 1e-158 | 498 |
| LLPS-Nia-1578 | Nicotiana attenuata | 38.6 | 5e-08 | 61.2 |
| LLPS-Fud-4313 | Fukomys damarensis | 37.79 | 1e-143 | 460 |
| LLPS-Gor-1097 | Gossypium raimondii | 37.61 | 9e-09 | 63.9 |
| LLPS-Hea-2472 | Helianthus annuus | 37.27 | 2e-07 | 59.3 |
| LLPS-Viv-1702 | Vitis vinifera | 37.04 | 1e-07 | 59.7 |
| LLPS-Brr-2184 | Brassica rapa | 36.7 | 9e-08 | 60.5 |
| LLPS-Thc-2228 | Theobroma cacao | 36.7 | 3e-09 | 65.5 |
| LLPS-Brn-0996 | Brassica napus | 36.7 | 1e-07 | 60.1 |
| LLPS-Xet-3946 | Xenopus tropicalis | 36.62 | 7e-138 | 444 |
| LLPS-Prp-0737 | Prunus persica | 36.59 | 1e-07 | 60.1 |
| LLPS-Glm-1363 | Glycine max | 34.53 | 5e-09 | 64.7 |
| LLPS-Met-0147 | Medicago truncatula | 33.81 | 1e-08 | 63.5 |
| LLPS-Zem-1676 | Zea mays | 33.11 | 3e-07 | 58.5 |
| LLPS-Tra-2542 | Triticum aestivum | 27.82 | 1e-07 | 60.1 |