• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pof-1755

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Aminomethyltransferase; Glycine cleavage system T protein
Ensembl Gene: ENSPFOG00000001187.1
Ensembl Protein: ENSPFOP00000001183.1
Organism: Poecilia formosa
Taxa ID: 48698
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

The glycine cleavage system catalyzes the degradation of glycine.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MWARVTAAGS  GLGLRASREC  VLRVTGAGCA  GKTPQERRDF  SAEAALKKTP  LFDFHRNNGG  60
61    KMVEFAGWSM  PVQYKDSHIA  SHMHTREHCS  IFDVSHMLQT  KIHGKDRIKF  MESLVVADIA  120
121   ELKDNQGTLS  LFTNEKGGII  DDLIVTKTNQ  GYLYVVSNAG  CADKDSAHMK  ARLAEYKAAG  180
181   FDVDLEFIDE  ALIALQGPTT  AQVLQAGLKG  DLSKLTFMTS  TLVTVFSVPD  CRVTRCGYTG  240
241   EDGVEISVPR  SRVVELAEKL  LSNNEVKLAG  LGARDSLRLE  AGLCLYGNDI  DETTTPVEAS  300
301   LVWTIGKRRR  QTKDFPGADI  IVPQIKAKTA  RKRVGLLSTG  PPVRQHTPIL  SPDGQVIGEV  360
361   TSGCPSPCLK  KNVAMGYVDA  AFAKNGAAVQ  VEIRKKTVPA  IVSKMPFVPT  NYYTG  415
Nucleotide CDS Sequence (FASTA)
1     ATGTGGGCTC  GGGTTACGGC  CGCGGGCTCG  GGGCTCGGGC  TGCGGGCTTC  CAGGGAGTGT  60
61    GTGCTGCGGG  TCACGGGTGC  TGGATGTGCG  GGGAAGACAC  CGCAGGAGAG  ACGGGATTTC  120
121   AGTGCAGAGG  CTGCCCTGAA  GAAAACCCCC  CTCTTTGACT  TTCACAGGAA  CAATGGTGGA  180
181   AAGATGGTGG  AGTTTGCTGG  CTGGAGCATG  CCTGTCCAGT  ACAAAGACAG  TCACATCGCC  240
241   TCACACATGC  ACACCAGGGA  GCACTGCTCC  ATCTTTGATG  TCAGCCACAT  GCTCCAGACC  300
301   AAAATCCACG  GAAAAGACCG  GATAAAGTTC  ATGGAGTCCC  TGGTGGTTGC  AGATATCGCA  360
361   GAGCTGAAGG  ACAACCAGGG  TACGTTGTCC  CTCTTCACCA  ACGAGAAAGG  AGGAATCATT  420
421   GATGACCTCA  TTGTGACAAA  GACCAATCAG  GGTTACCTCT  ACGTGGTCTC  CAACGCCGGC  480
481   TGCGCTGACA  AAGACTCGGC  TCATATGAAG  GCCAGACTGG  CAGAGTACAA  AGCTGCTGGG  540
541   TTTGATGTGG  ACCTGGAGTT  CATTGATGAA  GCCCTGATTG  CACTTCAAGG  TCCCACCACG  600
601   GCTCAGGTGC  TTCAGGCTGG  GCTGAAAGGA  GACCTCAGTA  AGCTGACCTT  CATGACCTCC  660
661   ACCCTGGTCA  CGGTGTTCAG  TGTTCCTGAC  TGCAGGGTGA  CCCGCTGCGG  ATACACCGGA  720
721   GAGGACGGGG  TGGAGATTTC  TGTTCCTCGT  TCCAGAGTGG  TTGAGCTGGC  AGAGAAGCTG  780
781   CTTAGCAACA  ATGAGGTGAA  GCTGGCCGGT  CTGGGAGCCA  GAGACAGTCT  TCGTCTGGAG  840
841   GCGGGACTTT  GTCTCTACGG  CAACGACATA  GATGAGACCA  CCACGCCTGT  GGAAGCCAGT  900
901   CTTGTTTGGA  CGATAGGGAA  GCGCAGGCGT  CAGACGAAGG  ATTTCCCTGG  CGCTGACATC  960
961   ATTGTGCCGC  AAATCAAAGC  CAAGACAGCC  AGGAAAAGAG  TTGGACTGCT  GTCCACCGGT  1020
1021  CCCCCAGTGA  GACAGCACAC  TCCCATCCTC  AGCCCTGATG  GACAGGTCAT  AGGGGAAGTG  1080
1081  ACCAGCGGCT  GTCCCTCTCC  CTGTCTGAAA  AAGAACGTCG  CCATGGGTTA  CGTGGACGCA  1140
1141  GCATTTGCCA  AGAACGGAGC  TGCCGTCCAG  GTTGAAATCA  GAAAGAAAAC  AGTCCCAGCC  1200
1201  ATCGTCAGCA  AGATGCCCTT  CGTCCCCACA  AACTACTACA  CTGGATAG  1248

▼ KEYWORD

ID
Family
Aminotransferase
Complete proteome
Mitochondrion
Reference proteome
Transferase
Transit peptide

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Mitochondrion
Molecular Function
Aminomethyltransferase activity
Molecular Function
Transaminase activity
Biological Process
Glycine catabolic process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Xim-3739Xiphophorus maculatus96.630.0 829
LLPS-Orn-0013Oreochromis niloticus86.620.0 749
LLPS-Scm-1715Scophthalmus maximus85.170.0 738
LLPS-Tar-1485Takifugu rubripes84.730.0 734
LLPS-Gaa-2398Gasterosteus aculeatus83.930.0 722
LLPS-Ten-1296Tetraodon nigroviridis83.120.0 694
LLPS-Orl-0661Oryzias latipes81.450.0 710
LLPS-Asm-2499Astyanax mexicanus81.310.0 555
LLPS-Scf-2997Scleropages formosus80.310.0 654
LLPS-Icp-4213Ictalurus punctatus79.790.0 665
LLPS-Dar-0350Danio rerio77.110.0 667
LLPS-Xet-2694Xenopus tropicalis76.090.0 598
LLPS-Lac-0656Latimeria chalumnae72.860.0 620
LLPS-Meg-0496Meleagris gallopavo72.62e-100 305
LLPS-Ora-0011Ornithorhynchus anatinus72.12e-163 469
LLPS-Mod-4238Monodelphis domestica71.770.0 577
LLPS-Ict-2416Ictidomys tridecemlineatus71.057e-54 184
LLPS-Cap-3097Cavia porcellus70.412e-133 394
LLPS-Dio-2643Dipodomys ordii70.240.0 553
LLPS-Ova-2717Ovis aries69.840.0 532
LLPS-Eqc-2570Equus caballus69.840.0 544
LLPS-Anc-1687Anolis carolinensis69.60.0 557
LLPS-Sus-4339Sus scrofa69.440.0 547
LLPS-Bot-3435Bos taurus69.350.0 535
LLPS-Orc-4243Oryctolagus cuniculus69.110.0 540
LLPS-Mup-1556Mustela putorius furo69.050.0 548
LLPS-Fud-3658Fukomys damarensis68.90.0 543
LLPS-Aim-3378Ailuropoda melanoleuca68.90.0 531
LLPS-Loa-1944Loxodonta africana68.780.0 541
LLPS-Gog-2235Gorilla gorilla68.630.0 536
LLPS-Pat-2235Pan troglodytes68.630.0 538
LLPS-Pap-4134Pan paniscus68.630.0 539
LLPS-Fec-0619Felis catus68.630.0 544
LLPS-Caf-2349Canis familiaris68.630.0 527
LLPS-Sah-3727Sarcophilus harrisii68.470.0 578
LLPS-Maf-0201Macaca fascicularis68.360.0 538
LLPS-Cea-4186Cercocebus atys68.360.0 538
LLPS-Caj-4856Callithrix jacchus68.360.0 537
LLPS-Mal-2752Mandrillus leucophaeus68.360.0 538
LLPS-Man-3465Macaca nemestrina68.360.0 538
LLPS-Mam-4044Macaca mulatta68.360.0 538
LLPS-Urm-1380Ursus maritimus68.340.0 544
LLPS-Cas-4068Carlito syrichta68.210.0 532
LLPS-Nol-0831Nomascus leucogenys68.185e-175 501
LLPS-Chs-3195Chlorocebus sabaeus68.10.0 536
LLPS-Paa-0389Papio anubis68.10.0 535
LLPS-Hos-3864Homo sapiens68.10.0 537
LLPS-Rhb-1908Rhinopithecus bieti68.10.0 535
LLPS-Poa-2746Pongo abelii67.890.0 541
LLPS-Otg-0213Otolemur garnettii67.640.0 541
LLPS-Aon-0638Aotus nancymaae66.930.0 520
LLPS-Mum-3298Mus musculus66.840.0 537
LLPS-Mea-4392Mesocricetus auratus66.840.0 538
LLPS-Fia-2057Ficedula albicollis65.725e-174 498
LLPS-Pes-2347Pelodiscus sinensis65.387e-67 222
LLPS-Myl-1148Myotis lucifugus65.210.0 554
LLPS-Ran-3335Rattus norvegicus60.791e-163 473
LLPS-Chr-1521Chlamydomonas reinhardtii57.376e-150 439
LLPS-Osl-0129Ostreococcus lucimarinus56.53e-134 399
LLPS-Cii-0037Ciona intestinalis56.373e-146 428
LLPS-Abg-1057Absidia glauca56.287e-147 430
LLPS-Cae-1267Caenorhabditis elegans56.025e-143 421
LLPS-Cis-2050Ciona savignyi55.982e-141 417
LLPS-Mua-1674Musa acuminata55.87e-136 403
LLPS-Sol-2450Solanum lycopersicum55.01e-139 412
LLPS-Cus-0381Cucumis sativus55.05e-140 413
LLPS-Orbr-2131Oryza brachyantha54.992e-133 401
LLPS-Brd-1301Brachypodium distachyon54.963e-135 401
LLPS-Orb-0882Oryza barthii54.723e-135 401
LLPS-Org-0507Oryza glaberrima54.723e-135 401
LLPS-Amt-0338Amborella trichopoda54.575e-135 401
LLPS-Sot-1293Solanum tuberosum54.476e-139 410
LLPS-Vir-1100Vigna radiata54.471e-136 405
LLPS-Nia-0914Nicotiana attenuata54.472e-137 407
LLPS-Tra-2139Triticum aestivum54.453e-134 399
LLPS-Hea-2080Helianthus annuus54.086e-127 378
LLPS-Viv-1417Vitis vinifera54.014e-138 409
LLPS-Lep-1815Leersia perrieri53.88e-126 375
LLPS-Prp-2323Prunus persica53.683e-137 406
LLPS-Glm-0238Glycine max53.429e-134 397
LLPS-Via-1539Vigna angularis53.422e-135 401
LLPS-Phv-1807Phaseolus vulgaris53.424e-135 401
LLPS-Ori-1326Oryza indica53.282e-77 247
LLPS-Sem-1136Selaginella moellendorffii53.213e-135 401
LLPS-Met-0392Medicago truncatula53.163e-135 402
LLPS-Mae-1472Manihot esculenta52.971e-134 400
LLPS-Pot-0163Populus trichocarpa52.891e-132 395
LLPS-Dac-1565Daucus carota52.882e-132 394
LLPS-Sob-1378Sorghum bicolor52.832e-133 397
LLPS-Thc-1820Theobroma cacao52.713e-135 401
LLPS-Coc-0195Corchorus capsularis52.653e-124 381
LLPS-Arl-2647Arabidopsis lyrata52.632e-132 394
LLPS-Art-0258Arabidopsis thaliana52.633e-132 394
LLPS-Zem-2095Zea mays52.562e-132 394
LLPS-Orgl-1468Oryza glumaepatula52.499e-135 400
LLPS-Orr-1117Oryza rufipogon52.499e-135 400
LLPS-Orni-1601Oryza nivara52.485e-136 403
LLPS-Ors-0904Oryza sativa52.485e-136 403
LLPS-Brn-3013Brassica napus52.478e-133 397
LLPS-Drm-2229Drosophila melanogaster52.455e-134 398
LLPS-Gor-0753Gossypium raimondii52.452e-134 399
LLPS-Bro-2336Brassica oleracea52.216e-133 395
LLPS-Sei-1453Setaria italica52.138e-136 403
LLPS-Brr-2662Brassica rapa51.437e-130 387
LLPS-Chc-1213Chondrus crispus50.933e-128 383
LLPS-Scc-1184Schizosaccharomyces cryophilus50.269e-126 376
LLPS-Php-1808Physcomitrella patens49.766e-132 393
LLPS-Gas-0832Galdieria sulphuraria49.732e-120 363
LLPS-Tru-1965Triticum urartu49.493e-84 269
LLPS-Usm-0431Ustilago maydis48.152e-112 344
LLPS-Scj-1536Schizosaccharomyces japonicus47.851e-112 343
LLPS-Scp-0585Schizosaccharomyces pombe47.615e-115 348
LLPS-Cym-0024Cyanidioschyzon merolae47.382e-101 317
LLPS-Spr-1196Sporisorium reilianum47.095e-110 338
LLPS-Nec-1486Neurospora crassa47.076e-106 328
LLPS-Yal-1207Yarrowia lipolytica46.973e-103 319
LLPS-Pytr-1181Pyrenophora triticirepentis46.462e-84 269
LLPS-Lem-1492Leptosphaeria maculans46.214e-104 323
LLPS-Pyt-0178Pyrenophora teres45.641e-106 330
LLPS-Crn-0776Cryptococcus neoformans45.294e-102 316
LLPS-Mao-1576Magnaporthe oryzae45.232e-103 321
LLPS-Phn-0709Phaeosphaeria nodorum44.682e-102 318
LLPS-Fus-1102Fusarium solani44.616e-99 309
LLPS-Blg-0960Blumeria graminis44.392e-101 316
LLPS-Asni-1417Aspergillus niger44.116e-87 279
LLPS-Gag-1309Gaeumannomyces graminis44.02e-100 314
LLPS-Dos-0175Dothistroma septosporum43.953e-101 317
LLPS-Tum-1095Tuber melanosporum43.859e-99 308
LLPS-Fuo-0102Fusarium oxysporum43.596e-98 306
LLPS-Fuv-0429Fusarium verticillioides43.539e-98 306
LLPS-Ast-1000Aspergillus terreus43.391e-86 278
LLPS-Trr-0106Trichoderma reesei43.221e-97 305
LLPS-Sac-0899Saccharomyces cerevisiae43.153e-91 288
LLPS-Kop-0179Komagataella pastoris43.045e-96 300
LLPS-Zyt-1145Zymoseptoria tritici43.045e-95 297
LLPS-Cogr-0786Colletotrichum graminicola42.931e-88 284
LLPS-Aso-1082Aspergillus oryzae42.543e-87 278
LLPS-Coo-0283Colletotrichum orbiculare42.35e-89 284
LLPS-Asf-0784Aspergillus flavus42.236e-87 279
LLPS-Trv-1664Trichoderma virens42.213e-93 294
LLPS-Nef-1243Neosartorya fischeri42.052e-82 267
LLPS-Asfu-0049Aspergillus fumigatus42.056e-83 269
LLPS-Cog-1294Colletotrichum gloeosporioides41.812e-90 286
LLPS-Beb-1342Beauveria bassiana41.82e-91 290
LLPS-Asc-1041Aspergillus clavatus41.733e-81 265
LLPS-Ved-1240Verticillium dahliae41.712e-90 288
LLPS-Pug-1153Puccinia graminis41.646e-83 267
LLPS-Miv-0967Microbotryum violaceum41.372e-89 285
LLPS-Put-0392Puccinia triticina40.886e-65 217
LLPS-Mel-0555Melampsora laricipopulina40.628e-82 264
LLPS-Asn-0477Aspergillus nidulans40.392e-82 268
LLPS-Leo-2287Lepisosteus oculatus26.734e-2097.1
LLPS-Gaga-3547Gallus gallus25.377e-1993.2
LLPS-Anp-2530Anas platyrhynchos23.837e-1477.8