LLPS-Poa-a566
RMDN3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Regulator of microtubule dynamics protein 3 |
| Gene Name: | RMDN3, FAM82A2, FAM82C |
| Ensembl Gene: | ENSPPYG00000006358.2 |
| Ensembl Protein: | ENSPPYP00000007199.2 |
| Organism: | Pongo abelii |
| Taxa ID: | 9601 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Involved in cellular calcium homeostasis regulation (By similarity). May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPPYT00000007498.2 | ENSPPYP00000007199.2 |
| UniProt | Q5R6Z1, RMD3_PONAB | |
| GeneBank | CR860332, CR859250 | CAH91430.1, CAH92469.1 |
| RefSeq | NM_001132367.1, XM_009249716.1, XM_009249717.1, XM_009249718.1 | NP_001125839.1, XP_009247991.1, XP_009247992.1, XP_009247993.1 |
| Entrez | 100172768 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSRLGALGGA RAGLGLLLGT AAGLGFLCLL YSQRWKRTQR HGRSQSLPNS LGYTQTSDPG 60 61 RQVMLLRAVP GGAGDASVLP SLPREGQEKV LDRLDFVLTS LVALRREVEE LRSSLRGLAG 120 121 EIVGEVRSHM EENQRVARRR RFPFVRERSD STGSSSVYFT ASSGATFTDA ESEGGYTTAN 180 181 AESDNERDSD KESEDGEDEV SCETVKMGRK DSLDLEEEAA SGASSALEAG GSSGLEDVLP 240 241 LLQQADELHR GDEQGKREGF QLLLNNKLVY GSRQDFLWRL ARAYSDMCEL TEEVSEKKSY 300 301 ALDGKEEAEA ALEKGDESAD CHLWYAVLCG QLAEHESIQR RIQSGFSFKE HVDKAIALQP 360 361 ENPMAYFLLG RWCYQVSHLS WLEKKTATAL LESPLSATVE DALQSFLKAE ELQPGFSKAG 420 421 RVYISKCYRE LGKNSEARWW MKLALELPDV TKEDLALQKD LEELEVILRD 470 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCTAGAC TGGGAGCCCT GGGTGGTGCC CGTGCCGGGC TGGGACTGTT GCTGGGTACC 60 61 GCCGCCGGCC TTGGATTCCT GTGCCTCCTT TACAGCCAAC GATGGAAACG GACCCAGCGT 120 121 CATGGCCGCA GCCAGAGCCT GCCCAACTCC CTGGGCTATA CGCAGACTTC AGATCCCGGA 180 181 CGCCAGGTGA TGCTCCTGCG GGCTGTCCCA GGTGGGGCTG GAGATGCCTC AGTGCTGCCC 240 241 AGCCTTCCAC GGGAAGGACA GGAGAAGGTG CTGGACCGCC TGGACTTTGT GCTGACCAGC 300 301 CTTGTGGCGC TGCGGCGGGA GGTGGAGGAG CTGAGAAGCA GCCTGCGAGG GCTCGCGGGG 360 361 GAGATTGTTG GGGAGGTCCG ATCCCACATG GAAGAGAACC AGAGAGTGGC TCGGCGGCGA 420 421 AGGTTTCCGT TTGTCCGGGA GAGGAGTGAC TCCACTGGCT CCAGCTCTGT CTACTTCACG 480 481 GCCTCCTCGG GAGCCACGTT CACAGATGCT GAGAGTGAAG GGGGTTACAC AACAGCCAAT 540 541 GCGGAGTCTG ACAATGAGCG GGACTCTGAC AAAGAAAGTG AGGACGGGGA AGATGAAGTG 600 601 AGCTGTGAGA CTGTGAAGAT GGGGAGAAAG GATTCTCTTG ACCTGGAGGA AGAGGCAGCT 660 661 TCAGGTGCCT CCAGTGCCCT GGAGGCTGGA GGTTCCTCAG GCTTGGAGGA TGTGCTGCCC 720 721 CTCCTGCAGC AGGCCGACGA GCTGCACAGG GGTGATGAGC AAGGCAAGCG GGAGGGCTTC 780 781 CAGCTCCTGC TCAACAACAA GCTGGTGTAT GGAAGCCGGC AGGACTTTCT CTGGCGCCTG 840 841 GCCCGAGCCT ACAGTGACAT GTGTGAGCTC ACTGAGGAGG TGAGCGAGAA GAAGTCATAT 900 901 GCCCTAGATG GAAAAGAAGA AGCAGAGGCT GCTCTGGAGA AGGGGGATGA GAGTGCTGAC 960 961 TGTCACCTGT GGTATGCGGT GCTTTGTGGT CAGCTGGCTG AGCATGAGAG CATCCAGAGG 1020 1021 CGCATCCAGA GTGGCTTTAG CTTCAAGGAG CATGTGGACA AAGCCATTGC TCTCCAGCCA 1080 1081 GAAAACCCCA TGGCTTACTT TCTTCTTGGC AGGTGGTGCT ATCAGGTCTC TCACCTGAGC 1140 1141 TGGCTAGAAA AAAAAACTGC TACAGCCTTG CTTGAAAGCC CTCTCAGTGC CACTGTGGAA 1200 1201 GATGCCCTCC AGAGCTTCCT AAAGGCTGAA GAACTACAGC CAGGATTTTC CAAAGCAGGA 1260 1261 AGGGTATATA TTTCCAAGTG CTACAGAGAA CTAGGGAAAA ACTCTGAAGC TAGATGGTGG 1320 1321 ATGAAGTTGG CCCTGGAGCT GCCAGATGTC ACGAAGGAGG ATTTGGCTCT CCAGAAGGAC 1380 1381 CTGGAAGAAT TGGAAGTCAT TTTACGAGAC TAA 1413 |
▼ KEYWORD
ID | Family |
Apoptosis | |
Coiled coil | |
Complete proteome | |
Cytoplasm | |
Cytoskeleton | |
Differentiation | |
Membrane | |
Microtubule | |
Mitochondrion | |
Mitochondrion outer membrane | |
Nucleus | |
Phosphoprotein | |
Reference proteome | |
Transmembrane | |
Transmembrane helix
|
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Integral component of membrane | |
Cellular Component | Microtubule | |
Cellular Component | Mitochondrial outer membrane | |
Cellular Component | Nucleus | |
Cellular Component | Spindle pole | |
Biological Process | Apoptotic process | |
Biological Process | Cell differentiation | |
Biological Process | Cellular calcium ion homeostasis |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a583 | Homo sapiens | 0.0 | 937 | undefined |
| LLPS-Mum-a578 | Mus musculus | 0.0 | 793 | undefined |