• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Poa-3996
VPS4B

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: VPS4B isoform 1
Gene Name: VPS4B, CR201_G0013525
Ensembl Gene: ENSPPYG00000009214.1
Ensembl Protein: ENSPPYP00000010341.1
Organism: Pongo abelii
Taxa ID: 9601
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSSTSPNLQK  AIDLASKAAQ  EDKAGNYEEA  LQLYQHAVQY  FLHVVKYEAQ  GDKAKQSIRA  60
61    KCTEYLDRAE  KLKEYLKNKE  KKAQKPVKEG  QPSPADEKGN  DSDGEGESDD  PEKKKLQNQL  120
121   QGAIVIERPN  VKWSDVAGLE  GAKEALKEAV  ILPIKFPHLF  TGKRTPWRGI  LLFGPPGTGK  180
181   SYLAKAVATE  ANNSTFFSIS  SSDLVSKWLG  ESEKLVKNLF  QLARENKPSI  IFIDEIDSLC  240
241   GSRSENESEA  ARRIKTEFLV  QMQGVGVDND  GILVLGATNI  PWVLDSAIRR  RFEKRIYIPL  300
301   PEPHARAAMF  KLHLGTTQNS  LTEADFRELG  RKTDGYSGAD  ISIIVRDALM  QPVRKVQSAT  360
361   HFKKVRGPSR  ADPNHLVDDL  LTPCSPGDPG  AIEMTWMDVP  GDKLLEPVVS  MSDMLRSLSN  420
421   TKPTVNEHDL  LKLKKFTEDF  GQEG  444
Nucleotide CDS Sequence (FASTA)
1     ATGTCATCCA  CTTCGCCCAA  CCTCCAGAAA  GCGATAGATC  TGGCTAGCAA  AGCAGCGCAA  60
61    GAAGACAAGG  CTGGGAACTA  CGAAGAAGCC  CTTCAGCTCT  ATCAGCATGC  TGTGCAGTAT  120
121   TTTCTTCATG  TCGTTAAATA  TGAAGCACAG  GGTGATAAAG  CCAAGCAAAG  TATCAGGGCA  180
181   AAGTGTACAG  AATATCTTGA  TAGAGCAGAA  AAACTAAAGG  AGTACCTGAA  AAATAAAGAG  240
241   AAAAAAGCAC  AGAAGCCAGT  GAAAGAAGGA  CAGCCGAGTC  CAGCAGATGA  GAAGGGGAAT  300
301   GACAGTGATG  GGGAAGGAGA  ATCTGATGAT  CCTGAAAAAA  AGAAACTACA  GAATCAACTT  360
361   CAAGGTGCCA  TTGTTATAGA  ACGACCAAAT  GTGAAATGGA  GTGACGTTGC  TGGACTTGAA  420
421   GGAGCCAAAG  AAGCACTGAA  AGAGGCTGTG  ATACTGCCTA  TTAAATTTCC  TCATCTTTTT  480
481   ACAGGCAAGA  GAACACCTTG  GAGGGGAATC  CTATTATTTG  GGCCGCCTGG  AACAGGAAAG  540
541   TCCTACTTAG  CCAAAGCTGT  AGCAACAGAA  GCCAACAACT  CAACATTTTT  TTCAATATCT  600
601   TCCTCTGATC  TTGTTTCTAA  GTGGCTAGGT  GAAAGTGAAA  AACTGGTTAA  GAATTTATTC  660
661   CAACTTGCCA  GAGAGAATAA  GCCCTCCATT  ATCTTCATTG  ATGAAATTGA  TTCTCTGTGT  720
721   GGTTCAAGAA  GTGAAAATGA  AAGTGAAGCC  GCACGTAGAA  TTAAGACGGA  GTTCCTAGTG  780
781   CAAATGCAAG  GGGTTGGTGT  AGACAATGAT  GGAATTTTGG  TTCTGGGAGC  TACAAATATA  840
841   CCCTGGGTTC  TGGATTCTGC  CATTAGGCGA  AGATTTGAGA  AACGAATTTA  TATTCCTTTG  900
901   CCGGAACCCC  ATGCCCGAGC  AGCAATGTTT  AAACTGCACC  TGGGGACCAC  TCAGAACAGT  960
961   CTGACGGAAG  CAGACTTTCG  GGAACTTGGG  AGGAAAACAG  ATGGTTATTC  AGGGGCAGAT  1020
1021  ATAAGTATCA  TTGTACGTGA  TGCCCTTATG  CAGCCTGTTA  GGAAAGTACA  GTCAGCTACT  1080
1081  CATTTTAAAA  AGGTTCGCGG  ACCTTCCCGA  GCTGATCCTA  ACCATCTTGT  AGATGATCTG  1140
1141  CTAACACCTT  GCTCTCCAGG  TGACCCTGGT  GCCATTGAAA  TGACATGGAT  GGATGTCCCT  1200
1201  GGAGATAAAC  TTTTGGAGCC  AGTTGTTTCC  ATGTCGGATA  TGTTGCGGTC  ACTATCTAAC  1260
1261  ACAAAACCTA  CAGTCAATGA  ACATGACTTG  TTGAAATTAA  AGAAGTTTAC  AGAAGATTTT  1320
1321  GGTCAAGAAG  GCTAA  1335

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pat-3891Pan troglodytes100.00.0 811
LLPS-Pap-1976Pan paniscus100.00.0 811
LLPS-Hos-3929Homo sapiens100.00.0 830
LLPS-Rhb-3669Rhinopithecus bieti99.770.0 829
LLPS-Gog-3079Gorilla gorilla99.770.0 829
LLPS-Man-2082Macaca nemestrina99.550.0 824
LLPS-Mam-3409Macaca mulatta99.550.0 828
LLPS-Cea-0596Cercocebus atys99.550.0 824
LLPS-Chs-4788Chlorocebus sabaeus99.550.0 828
LLPS-Maf-4387Macaca fascicularis99.550.0 824
LLPS-Mal-2989Mandrillus leucophaeus99.550.0 828
LLPS-Paa-0064Papio anubis99.320.0 822
LLPS-Caj-4624Callithrix jacchus99.310.0 806
LLPS-Aon-1898Aotus nancymaae99.080.0 805
LLPS-Nol-4462Nomascus leucogenys98.640.0 806
LLPS-Fud-2888Fukomys damarensis96.850.0 808
LLPS-Dio-0504Dipodomys ordii96.850.0 797
LLPS-Bot-4434Bos taurus96.620.0 806
LLPS-Ova-1169Ovis aries95.950.0 805
LLPS-Loa-3516Loxodonta africana95.720.0 798
LLPS-Cap-4162Cavia porcellus95.270.0 796
LLPS-Ere-0016Erinaceus europaeus93.470.0 711
LLPS-Pes-0723Pelodiscus sinensis90.110.0 740
LLPS-Gaga-3964Gallus gallus90.00.0 736
LLPS-Fia-0651Ficedula albicollis89.930.0 737
LLPS-Tag-2911Taeniopygia guttata89.240.0 731
LLPS-Anp-3138Anas platyrhynchos88.460.0 734
LLPS-Meg-3132Meleagris gallopavo87.240.0 737
LLPS-Dar-0802Danio rerio86.010.0 721
LLPS-Icp-1474Ictalurus punctatus84.680.0 721
LLPS-Scm-3733Scophthalmus maximus83.60.0 704
LLPS-Orn-1902Oreochromis niloticus83.180.0 711
LLPS-Gaa-2483Gasterosteus aculeatus83.070.0 706
LLPS-Pof-2988Poecilia formosa82.270.0 702
LLPS-Xim-3389Xiphophorus maculatus82.270.0 703
LLPS-Anc-0212Anolis carolinensis82.090.0 695
LLPS-Asm-0401Astyanax mexicanus81.690.0 695
LLPS-Otg-0663Otolemur garnettii81.420.0 691
LLPS-Leo-1432Lepisosteus oculatus80.950.0 698
LLPS-Scf-0592Scleropages formosus80.950.0 696
LLPS-Tar-0557Takifugu rubripes80.920.0 684
LLPS-Ten-3539Tetraodon nigroviridis80.780.0 682
LLPS-Sah-1239Sarcophilus harrisii80.730.0 687
LLPS-Mea-3071Mesocricetus auratus80.730.0 684
LLPS-Urm-0919Ursus maritimus80.690.0 685
LLPS-Orc-0586Oryctolagus cuniculus80.680.0 691
LLPS-Cas-0902Carlito syrichta80.680.0 691
LLPS-Mum-1587Mus musculus80.680.0 691
LLPS-Ran-0091Rattus norvegicus80.680.0 691
LLPS-Aim-2510Ailuropoda melanoleuca80.550.0 688
LLPS-Myl-2869Myotis lucifugus80.50.0 686
LLPS-Ict-3080Ictidomys tridecemlineatus80.450.0 689
LLPS-Sus-0550Sus scrofa80.450.0 692
LLPS-Mup-2478Mustela putorius furo80.450.0 692
LLPS-Caf-0571Canis familiaris80.410.0 690
LLPS-Eqc-1220Equus caballus80.150.0 638
LLPS-Fec-0830Felis catus80.00.0 689
LLPS-Mod-1502Monodelphis domestica79.730.0 692
LLPS-Lac-0057Latimeria chalumnae79.680.0 689
LLPS-Ora-0436Ornithorhynchus anatinus79.630.0 684
LLPS-Xet-0204Xenopus tropicalis78.910.0 694
LLPS-Tut-1477Tursiops truncatus78.570.0 681
LLPS-Orl-3324Oryzias latipes78.00.0 675
LLPS-Put-0907Puccinia triticina76.362e-84 266
LLPS-Drm-1454Drosophila melanogaster73.970.0 627
LLPS-Cis-1612Ciona savignyi72.27e-117 348
LLPS-Cii-1044Ciona intestinalis67.810.0 592
LLPS-Cae-0121Caenorhabditis elegans66.740.0 589
LLPS-Hov-0585Hordeum vulgare61.086e-139 416
LLPS-Pug-0580Puccinia graminis60.592e-173 501
LLPS-Asg-0429Ashbya gossypii60.52e-168 488
LLPS-Sac-1212Saccharomyces cerevisiae60.51e-172 499
LLPS-Mel-0130Melampsora laricipopulina60.363e-170 493
LLPS-Crn-0895Cryptococcus neoformans60.271e-165 481
LLPS-Kop-0338Komagataella pastoris60.189e-175 504
LLPS-Tum-1042Tuber melanosporum59.452e-167 485
LLPS-Nec-1292Neurospora crassa59.244e-169 490
LLPS-Miv-1422Microbotryum violaceum58.743e-167 485
LLPS-Blg-0019Blumeria graminis58.373e-168 487
LLPS-Scp-1222Schizosaccharomyces pombe58.016e-159 464
LLPS-Cym-0316Cyanidioschyzon merolae57.783e-126 384
LLPS-Asf-0380Aspergillus flavus57.666e-168 487
LLPS-Ast-0832Aspergillus terreus57.434e-169 489
LLPS-Dos-0949Dothistroma septosporum57.436e-165 479
LLPS-Asc-0067Aspergillus clavatus57.439e-169 489
LLPS-Scc-1154Schizosaccharomyces cryophilus57.341e-157 460
LLPS-Yal-0634Yarrowia lipolytica57.181e-164 478
LLPS-Asfu-0833Aspergillus fumigatus57.177e-169 489
LLPS-Lem-0542Leptosphaeria maculans57.144e-160 467
LLPS-Spr-0962Sporisorium reilianum57.051e-167 487
LLPS-Asni-0022Aspergillus niger56.983e-168 487
LLPS-Nef-0231Neosartorya fischeri56.956e-168 487
LLPS-Asn-0968Aspergillus nidulans56.795e-170 492
LLPS-Chr-1513Chlamydomonas reinhardtii56.721e-162 473
LLPS-Usm-0594Ustilago maydis56.212e-166 484
LLPS-Aso-1228Aspergillus oryzae56.211e-165 481
LLPS-Gas-0335Galdieria sulphuraria56.082e-161 471
LLPS-Mao-0131Magnaporthe oryzae55.997e-159 463
LLPS-Scj-1478Schizosaccharomyces japonicus55.981e-157 461
LLPS-Beb-1235Beauveria bassiana55.868e-149 438
LLPS-Pytr-0885Pyrenophora triticirepentis55.74e-155 454
LLPS-Zem-2303Zea mays55.669e-153 448
LLPS-Cog-0741Colletotrichum gloeosporioides55.611e-154 452
LLPS-Cogr-1560Colletotrichum graminicola55.585e-152 446
LLPS-Sob-1314Sorghum bicolor55.535e-155 454
LLPS-Chc-0879Chondrus crispus55.385e-148 436
LLPS-Coo-1010Colletotrichum orbiculare55.365e-153 449
LLPS-Gag-0359Gaeumannomyces graminis55.311e-148 438
LLPS-Orni-0044Oryza nivara55.15e-144 439
LLPS-Fus-0219Fusarium solani55.051e-148 437
LLPS-Trr-0807Trichoderma reesei54.943e-150 441
LLPS-Fuo-0279Fusarium oxysporum54.941e-148 437
LLPS-Fuv-1141Fusarium verticillioides54.948e-149 438
LLPS-Orbr-1690Oryza brachyantha54.887e-150 441
LLPS-Zyt-0226Zymoseptoria tritici54.853e-159 464
LLPS-Pyt-0568Pyrenophora teres54.812e-150 442
LLPS-Trv-0993Trichoderma virens54.715e-150 441
LLPS-Orr-2069Oryza rufipogon54.671e-144 439
LLPS-Mua-2472Musa acuminata54.653e-154 451
LLPS-Dac-0537Daucus carota54.595e-147 434
LLPS-Php-1576Physcomitrella patens54.573e-151 444
LLPS-Glm-2644Glycine max54.59e-148 435
LLPS-Ved-0260Verticillium dahliae54.481e-155 455
LLPS-Orp-1303Oryza punctata54.425e-150 441
LLPS-Org-1671Oryza glaberrima54.425e-150 441
LLPS-Bro-0918Brassica oleracea54.422e-149 439
LLPS-Ori-0496Oryza indica54.425e-150 441
LLPS-Orb-0309Oryza barthii54.424e-145 440
LLPS-Orgl-1181Oryza glumaepatula54.422e-145 441
LLPS-Tra-0488Triticum aestivum54.382e-154 452
LLPS-Brr-2381Brassica rapa54.23e-147 434
LLPS-Hea-0104Helianthus annuus54.181e-147 435
LLPS-Pot-2026Populus trichocarpa54.121e-151 445
LLPS-Map-0592Magnaporthe poae54.112e-155 456
LLPS-Viv-0676Vitis vinifera53.957e-150 441
LLPS-Amt-0912Amborella trichopoda53.951e-149 440
LLPS-Arl-2110Arabidopsis lyrata53.932e-149 439
LLPS-Brd-1758Brachypodium distachyon53.932e-152 447
LLPS-Sei-2178Setaria italica53.864e-153 449
LLPS-Nia-2320Nicotiana attenuata53.745e-150 441
LLPS-Brn-2430Brassica napus53.744e-149 439
LLPS-Art-2900Arabidopsis thaliana53.712e-148 437
LLPS-Sol-2004Solanum lycopersicum53.593e-145 429
LLPS-Mae-1865Manihot esculenta53.453e-150 441
LLPS-Thc-2121Theobroma cacao53.415e-151 444
LLPS-Sem-1833Selaginella moellendorffii53.386e-146 431
LLPS-Lep-2095Leersia perrieri53.064e-145 429
LLPS-Via-0535Vigna angularis53.052e-143 424
LLPS-Phv-0788Phaseolus vulgaris53.033e-142 421
LLPS-Osl-0483Ostreococcus lucimarinus52.832e-140 417
LLPS-Vir-0212Vigna radiata52.821e-142 422
LLPS-Coc-0217Corchorus capsularis52.758e-150 441
LLPS-Ors-0361Oryza sativa52.612e-142 422
LLPS-Orm-0701Oryza meridionalis52.614e-140 416
LLPS-Sot-1975Solanum tuberosum52.611e-144 427
LLPS-Prp-0208Prunus persica52.333e-150 442
LLPS-Cus-1022Cucumis sativus52.334e-147 434
LLPS-Gor-1335Gossypium raimondii52.322e-149 439
LLPS-Met-0938Medicago truncatula50.882e-143 424
LLPS-Phn-0529Phaeosphaeria nodorum49.339e-130 389
LLPS-Tru-1948Triticum urartu46.082e-138 414