LLPS-Poa-3608
NEXN
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Nexilin F-actin binding protein |
| Gene Name: | NEXN |
| Ensembl Gene: | ENSPPYG00000001220.2 |
| Ensembl Protein: | ENSPPYP00000001416.2 |
| Organism: | Pongo abelii |
| Taxa ID: | 9601 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPPYT00000001461.2 | ENSPPYP00000001416.2 |
| UniProt | H2N6Z5, H2N6Z5_PONAB | |
| GeneBank | ABGA01063748, ABGA01063750, ABGA01063746, ABGA01063749, ABGA01063751, ABGA01063747, ABGA01063753, ABGA01063752, ABGA01063744, ABGA01063745 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MREQAAHQDF YGNLLLETAA AAAAAARVLP AAGAEVLAAR APRPLPTGRR DAHSPSTRKE 60 61 GASPVTAPGG CKYIQSFIIS PRPHRANMND ISQKVEILLS SSKPVPKTYV PKLGKGDVKD 120 121 KFEAMQRARE ERNQRRSRDE KQRRKEQYIR EREWNRRKQE IKEMLASDDE EDVSSKVEKA 180 181 YVPKLTGTVK GRFAEMEKQR QEEQRKRTEE ERKRRIEQDM LEKRKIQREL AKRAEQIEDI 240 241 NNTGTESASE EGDDSLLITV VPVKSYKTSG KMKKNFEDLE KEREEKERIK YEEDKRIRYE 300 301 EQRRSLKEAK CLSLVMDDEI ESEAKKESLS PGKLKLTFEE LERQRQENRK KQAEEEARKR 360 361 LEEEKRAFEE ARRQMVNEED ENQDTAKIFK GYRPGKLKLS FEEMERQRRE DEKRKAEEEA 420 421 RRRIEEEKKA FAEARRNMVV DDDSPEMCKT ISQESLTPGK LEINFEELLK QKMEEEKRRT 480 481 EEERKHKLEM EKQEFEQLRQ EMGEEEEENE TFGLSREYEE LIKLKRSGSI QAKNLKSKFE 540 541 KIGQLSEKEI QKKIEEERAR RRAIDLEIKE REAENFHEED DVDVRPARKS EAPFTHKVNM 600 601 KARFEQMAKA REEEEQRRIE EQKLLRMQFE QREIDAALQK KREEEEEEEG SIMNGSTTED 660 661 EEQTRSGAPW FKKPLKNTSV VDSEPVRFTV KVTGEPKPEI TWWFEGEILQ DGEDYQYIER 720 721 GETYCLYLPE TFPEDGGEYM CKAVNNKGSA ASTCILTIET DDY 763 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCGGGAAC AGGCTGCGCA CCAGGACTTT TATGGAAACT TGCTGCTGGA GACGGCGGCG 60 61 GCGGCGGCAG CGGCAGCCAG AGTACTCCCA GCGGCTGGAG CAGAAGTGTT AGCGGCCAGA 120 121 GCTCCCAGAC CCCTACCCAC AGGCAGGCGG GACGCGCACA GTCCCTCTAC GCGAAAAGAA 180 181 GGAGCTTCGC CGGTCACCGC TCCTGGAGGG TGCAAATATA TACAGAGCTT CATAATCAGC 240 241 CCAAGACCAC ACAGAGCAAA CATGAATGAT ATTTCCCAAA AGGTTGAGAT TCTGCTTTCT 300 301 TCATCTAAAC CTGTCCCAAA AACCTATGTA CCAAAACTTG GCAAGGGTGA TGTAAAGGAT 360 361 AAGTTTGAAG CCATGCAGAG AGCCAGGGAA GAAAGAAATC AAAGGAGATC TAGAGACGAA 420 421 AAGCAAAGAA GAAAAGAACA ATATATTAGA GAGAGAGAAT GGAACAGGAG AAAGCAGGAG 480 481 ATTAAAGAAA TGCTTGCTTC TGATGATGAG GAAGATGTAT CTTCTAAAGT AGAAAAGGCT 540 541 TATGTTCCAA AATTAACAGG AACTGTTAAG GGTAGATTTG CTGAAATGGA GAAACAAAGA 600 601 CAAGAGGAAC AAAGGAAGAG AACAGAGGAG GAACGAAAAC GCAGAATTGA GCAGGATATG 660 661 TTAGAAAAGA GGAAAATACA GCGTGAATTA GCAAAAAGGG CTGAACAGAT TGAGGACATA 720 721 AACAATACGG GAACTGAATC AGCATCAGAG GAAGGAGATG ATTCACTACT TATAACTGTG 780 781 GTACCTGTCA AATCATATAA AACATCTGGA AAAATGAAAA AGAATTTTGA GGATCTAGAA 840 841 AAAGAACGTG AAGAGAAAGA AAGGATCAAG TATGAGGAAG ATAAAAGAAT AAGATATGAA 900 901 GAACAACGAC GCTCTCTCAA GGAAGCAAAG TGTCTTTCAT TAGTTATGGA TGATGAAATA 960 961 GAAAGTGAAG CAAAAAAAGA ATCACTTTCT CCTGGAAAAT TGAAACTAAC TTTTGAAGAA 1020 1021 CTGGAGCGAC AAAGACAAGA AAACCGAAAG AAGCAAGCTG AAGAGGAAGC AAGAAAACGT 1080 1081 TTAGAAGAAG AGAAGCGTGC TTTTGAAGAA GCAAGGCGGC AAATGGTAAA TGAAGAAGAT 1140 1141 GAAAACCAAG ACACAGCAAA AATTTTTAAA GGGTACCGCC CTGGTAAACT CAAACTCAGT 1200 1201 TTTGAAGAAA TGGAAAGGCA AAGAAGAGAA GATGAAAAAA GGAAAGCAGA AGAAGAAGCC 1260 1261 AGAAGGAGAA TAGAGGAAGA AAAGAAGGCG TTTGCTGAAG CAAGGAGAAA CATGGTAGTA 1320 1321 GATGATGACT CCCCAGAGAT GTGTAAGACA ATCTCTCAAG AATCTCTTAC ACCGGGAAAA 1380 1381 CTGGAAATTA ATTTTGAAGA ATTATTAAAA CAAAAAATGG AAGAAGAAAA ACGACGAACA 1440 1441 GAGGAGGAAC GGAAGCATAA GCTAGAAATG GAGAAACAAG AATTTGAACA ACTGAGACAG 1500 1501 GAAATGGGAG AGGAAGAGGA AGAAAATGAA ACCTTTGGAT TGAGCAGAGA ATATGAAGAA 1560 1561 CTGATCAAAT TAAAAAGGAG TGGCTCTATT CAAGCTAAAA ACCTAAAAAG CAAGTTTGAA 1620 1621 AAAATTGGAC AGTTGTCTGA AAAAGAAATA CAGAAAAAAA TAGAAGAAGA GCGAGCAAGA 1680 1681 AGGAGAGCAA TTGACCTTGA AATTAAAGAG CGAGAAGCAG AAAATTTTCA TGAGGAAGAT 1740 1741 GATGTTGATG TTAGGCCTGC AAGAAAAAGC GAGGCTCCAT TTACTCACAA AGTGAATATG 1800 1801 AAAGCTAGAT TTGAACAGAT GGCTAAGGCA AGAGAAGAAG AAGAACAAAG AAGAATTGAA 1860 1861 GAACAAAAGT TACTACGCAT GCAGTTTGAA CAAAGGGAAA TTGATGCAGC ACTACAAAAG 1920 1921 AAAAGAGAAG AGGAGGAGGA GGAAGAAGGT AGCATCATGA ATGGCTCCAC TACTGAAGAT 1980 1981 GAAGAGCAAA CCAGATCAGG AGCTCCATGG TTCAAGAAGC CTCTTAAAAA CACGTCAGTT 2040 2041 GTAGACAGTG AGCCAGTCAG ATTTACTGTT AAAGTAACAG GAGAACCCAA ACCAGAAATT 2100 2101 ACATGGTGGT TTGAAGGAGA AATACTGCAG GATGGAGAAG ACTATCAATA TATTGAAAGG 2160 2161 GGAGAAACTT ACTGCCTTTA CTTACCAGAA ACTTTCCCAG AAGATGGAGG AGAGTATATG 2220 2221 TGTAAAGCAG TCAACAATAA AGGATCTGCA GCTAGTACCT GTATTCTTAC CATTGAAACT 2280 2281 GATGACTACT AG 2292 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Gog-2673 | Gorilla gorilla | 99.26 | 0.0 | 849 |
| LLPS-Pap-2721 | Pan paniscus | 98.81 | 0.0 | 842 |
| LLPS-Hos-0247 | Homo sapiens | 98.81 | 0.0 | 838 |
| LLPS-Paa-1697 | Papio anubis | 98.66 | 0.0 | 843 |
| LLPS-Nol-2506 | Nomascus leucogenys | 98.66 | 0.0 | 843 |
| LLPS-Cea-1021 | Cercocebus atys | 98.51 | 0.0 | 844 |
| LLPS-Mal-4421 | Mandrillus leucophaeus | 98.51 | 0.0 | 846 |
| LLPS-Man-2676 | Macaca nemestrina | 98.51 | 0.0 | 843 |
| LLPS-Maf-3833 | Macaca fascicularis | 98.37 | 0.0 | 841 |
| LLPS-Pat-0006 | Pan troglodytes | 98.37 | 0.0 | 837 |
| LLPS-Mam-1145 | Macaca mulatta | 98.37 | 0.0 | 845 |
| LLPS-Aon-0986 | Aotus nancymaae | 97.92 | 0.0 | 836 |
| LLPS-Chs-0474 | Chlorocebus sabaeus | 97.72 | 0.0 | 891 |
| LLPS-Rhb-2878 | Rhinopithecus bieti | 95.69 | 0.0 | 785 |
| LLPS-Aim-0747 | Ailuropoda melanoleuca | 95.4 | 0.0 | 798 |
| LLPS-Caf-4587 | Canis familiaris | 95.27 | 0.0 | 807 |
| LLPS-Urm-1845 | Ursus maritimus | 94.95 | 0.0 | 792 |
| LLPS-Myl-4167 | Myotis lucifugus | 94.8 | 0.0 | 799 |
| LLPS-Sus-3774 | Sus scrofa | 94.67 | 0.0 | 800 |
| LLPS-Fec-3074 | Felis catus | 94.51 | 0.0 | 795 |
| LLPS-Caj-4471 | Callithrix jacchus | 94.5 | 0.0 | 938 |
| LLPS-Ict-1266 | Ictidomys tridecemlineatus | 94.3 | 0.0 | 791 |
| LLPS-Bot-2808 | Bos taurus | 93.93 | 0.0 | 794 |
| LLPS-Mup-1249 | Mustela putorius furo | 93.91 | 0.0 | 688 |
| LLPS-Ova-2570 | Ovis aries | 93.34 | 0.0 | 790 |
| LLPS-Mea-0298 | Mesocricetus auratus | 91.73 | 3e-159 | 480 |
| LLPS-Otg-3247 | Otolemur garnettii | 91.56 | 0.0 | 669 |
| LLPS-Cap-3524 | Cavia porcellus | 91.42 | 0.0 | 747 |
| LLPS-Fud-2310 | Fukomys damarensis | 90.53 | 0.0 | 749 |
| LLPS-Dio-2404 | Dipodomys ordii | 90.38 | 0.0 | 777 |
| LLPS-Orc-2662 | Oryctolagus cuniculus | 89.78 | 0.0 | 866 |
| LLPS-Mum-4241 | Mus musculus | 88.76 | 0.0 | 761 |
| LLPS-Loa-2704 | Loxodonta africana | 88.2 | 0.0 | 766 |
| LLPS-Cas-3829 | Carlito syrichta | 88.15 | 0.0 | 722 |
| LLPS-Eqc-3173 | Equus caballus | 86.48 | 0.0 | 842 |
| LLPS-Ran-0432 | Rattus norvegicus | 86.39 | 0.0 | 735 |
| LLPS-Anp-3086 | Anas platyrhynchos | 85.89 | 4e-128 | 405 |
| LLPS-Meg-3155 | Meleagris gallopavo | 85.41 | 3e-128 | 406 |
| LLPS-Sah-0966 | Sarcophilus harrisii | 84.07 | 0.0 | 701 |
| LLPS-Pes-3562 | Pelodiscus sinensis | 82.65 | 0.0 | 683 |
| LLPS-Ora-2613 | Ornithorhynchus anatinus | 80.85 | 2e-140 | 426 |
| LLPS-Fia-3757 | Ficedula albicollis | 80.09 | 0.0 | 662 |
| LLPS-Tag-0194 | Taeniopygia guttata | 79.67 | 0.0 | 623 |
| LLPS-Anc-1779 | Anolis carolinensis | 79.23 | 0.0 | 616 |
| LLPS-Gaga-1434 | Gallus gallus | 77.78 | 0.0 | 553 |
| LLPS-Leo-2194 | Lepisosteus oculatus | 77.68 | 9e-105 | 345 |
| LLPS-Orl-1311 | Oryzias latipes | 75.16 | 2e-98 | 330 |
| LLPS-Scf-0523 | Scleropages formosus | 75.08 | 1e-98 | 328 |
| LLPS-Mod-1375 | Monodelphis domestica | 74.63 | 0.0 | 597 |
| LLPS-Pof-2249 | Poecilia formosa | 73.64 | 5e-97 | 327 |
| LLPS-Dar-2494 | Danio rerio | 73.48 | 7e-103 | 342 |
| LLPS-Xim-3944 | Xiphophorus maculatus | 73.33 | 2e-95 | 322 |
| LLPS-Lac-1822 | Latimeria chalumnae | 73.32 | 1e-107 | 352 |
| LLPS-Icp-3224 | Ictalurus punctatus | 72.05 | 5e-97 | 327 |
| LLPS-Tar-0037 | Takifugu rubripes | 71.17 | 2e-106 | 351 |
| LLPS-Xet-0829 | Xenopus tropicalis | 68.32 | 6e-119 | 382 |
| LLPS-Ten-1227 | Tetraodon nigroviridis | 65.85 | 3e-133 | 416 |
| LLPS-Asm-3483 | Astyanax mexicanus | 64.8 | 1e-105 | 351 |
| LLPS-Orn-3385 | Oreochromis niloticus | 58.95 | 2e-137 | 433 |
| LLPS-Gaa-1976 | Gasterosteus aculeatus | 58.63 | 2e-150 | 461 |
| LLPS-Scm-1029 | Scophthalmus maximus | 57.64 | 7e-134 | 425 |
| LLPS-Cii-0014 | Ciona intestinalis | 40.86 | 7e-21 | 102 |