• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Poa-3123
KHSRP

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: KH-type splicing regulatory protein
Gene Name: KHSRP
Ensembl Gene: ENSPPYG00000009454.1
Ensembl Protein: ENSPPYP00000010601.1
Organism: Pongo abelii
Taxa ID: 9601
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, Perinucleolar compartment, P-body, Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSPPYT00000011018.1ENSPPYP00000010601.1
UniProtH2NX81, H2NX81_PONAB
GeneBankABGA01082498, ABGA01082497

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSDYSTGGPP  IAAKIGGDAA  TTVNNSTPDF  GFGGQKRQLE  DGDQPESKKL  ASQGDSISSQ  60
61    LGPIHPPPRT  SMTEEYRVPD  GMVGLIIGRG  GEQINKIQQD  SGCKVQISPD  SGGLPERSVS  120
121   LTGAPESVQK  AKMMLDDIVS  RGRGGPPGQF  HDNANGGQNG  TVQEIMIPAG  KAGLVIGKGG  180
181   ETIKQLQERA  GVKMILIQDG  SQNTNVDKPL  RIIGDPYKVQ  QACEMVMDIL  RERDQGGFGD  240
241   RNEYGSRIGG  GIDVPVPRHS  VGVVIGRSGE  MIKKIQNDAG  VRIQFKQDDG  TGPEKIAHIM  300
301   GPPDRCEHAA  RIINDLLQSL  RSGPPGPPGG  PGMPPGGRGR  GRGQGNWGPP  GGEMTFSIPT  360
361   HKCGLVIGRG  GENVKAINQQ  TGAFVEISRQ  LPPNGDPNFK  LFIIRGSPQQ  IDHAKQLIEE  420
421   KIEGPLCPVG  PGPGGPGPAG  PMGPFNPGPF  NQGPPGAPPH  AGGPPPHQYP  PQGWGNTYPQ  480
481   WQPPAPHDPS  KAAAAAADPN  AAWAAYYSHY  YQQPPGPVPG  PAPAPAAPPA  QGEPPQPPPT  540
541   GQSDYTKAWE  EYYKKIGQQP  QQPGAPPQQD  YTKAWEEYYK  KQAQVATGGG  PGAPPGFLAP  600
601   PMVFEPLLSS  ALAQLPRPRP  SPLPGLVCCL  FICSRGD  637
Nucleotide CDS Sequence (FASTA)
1     ATGTCGGACT  ACAGCACGGG  AGGACCCCCG  ATTGCAGCTA  AAATTGGAGG  TGATGCCGCC  60
61    ACGACAGTGA  ATAACAGCAC  CCCTGATTTT  GGTTTTGGGG  GCCAAAAGAG  ACAGTTGGAA  120
121   GATGGAGATC  AACCGGAGAG  CAAGAAGCTG  GCTTCCCAGG  GAGACTCAAT  CAGTTCTCAA  180
181   CTTGGACCCA  TCCATCCTCC  CCCAAGGACT  TCAATGACAG  AAGAGTACAG  GGTCCCAGAC  240
241   GGCATGGTGG  GCCTGATCAT  TGGCAGAGGA  GGTGAACAAA  TTAACAAAAT  CCAACAGGAT  300
301   TCAGGCTGCA  AAGTACAGAT  TTCTCCAGAC  AGCGGTGGCC  TACCCGAGCG  CAGTGTGTCC  360
361   TTGACAGGAG  CCCCAGAATC  TGTCCAGAAA  GCCAAGATGA  TGCTGGACGA  CATTGTGTCT  420
421   CGGGGTCGTG  GGGGCCCCCC  AGGACAGTTC  CATGACAATG  CCAACGGGGG  CCAGAACGGC  480
481   ACCGTGCAGG  AGATCATGAT  CCCCGCAGGC  AAGGCCGGCC  TGGTCATCGG  CAAGGGCGGG  540
541   GAGACCATTA  AGCAGCTGCA  GGAACGCGCT  GGAGTGAAGA  TGATCTTAAT  TCAGGACGGA  600
601   TCTCAGAATA  CGAACGTGGA  CAAACCTCTC  CGGATCATTG  GGGATCCTTA  CAAAGTGCAG  660
661   CAAGCCTGTG  AGATGGTGAT  GGACATCCTC  CGGGAACGTG  ACCAAGGCGG  CTTTGGGGAC  720
721   CGGAATGAGT  ACGGATCTCG  GATTGGCGGA  GGCATCGATG  TGCCAGTGCC  CAGGCATTCT  780
781   GTTGGCGTGG  TCATTGGCCG  GAGTGGAGAG  ATGATCAAGA  AGATCCAGAA  TGACGCTGGC  840
841   GTGCGGATAC  AGTTCAAGCA  AGATGACGGG  ACAGGGCCTG  AGAAGATTGC  TCATATAATG  900
901   GGGCCCCCAG  ACAGGTGTGA  GCACGCAGCC  CGGATCATCA  ACGATCTCCT  CCAGAGCCTC  960
961   AGGAGTGGTC  CTCCAGGTCC  TCCAGGGGGT  CCAGGCATGC  CCCCGGGGGG  CCGAGGCCGG  1020
1021  GGAAGAGGCC  AAGGCAATTG  GGGTCCCCCT  GGCGGGGAGA  TGACCTTCTC  CATCCCCACT  1080
1081  CACAAGTGTG  GGCTGGTCAT  CGGCCGAGGT  GGCGAGAATG  TGAAAGCCAT  AAACCAGCAG  1140
1141  ACGGGAGCCT  TCGTAGAGAT  CTCCCGGCAG  CTGCCACCCA  ACGGGGACCC  CAACTTCAAG  1200
1201  TTGTTCATCA  TCCGGGGTTC  ACCCCAGCAG  ATTGACCACG  CCAAGCAGCT  TATCGAGGAA  1260
1261  AAGATCGAGG  GTCCTCTCTG  CCCAGTTGGA  CCAGGCCCAG  GCGGCCCAGG  CCCTGCTGGC  1320
1321  CCAATGGGGC  CCTTCAATCC  TGGGCCCTTC  AACCAGGGGC  CACCCGGGGC  TCCCCCACAT  1380
1381  GCCGGGGGGC  CCCCTCCTCA  CCAGTACCCA  CCCCAGGGCT  GGGGCAATAC  CTACCCCCAG  1440
1441  TGGCAGCCGC  CTGCTCCTCA  TGACCCAAGC  AAAGCAGCTG  CAGCGGCCGC  GGACCCCAAC  1500
1501  GCCGCGTGGG  CCGCCTACTA  CTCACACTAC  TACCAGCAGC  CCCCGGGCCC  CGTCCCCGGC  1560
1561  CCCGCACCGG  CCCCTGCGGC  CCCACCGGCT  CAGGGTGAGC  CCCCTCAGCC  CCCACCCACC  1620
1621  GGCCAGTCGG  ACTACACTAA  GGCCTGGGAA  GAGTATTACA  AAAAGATCGG  CCAGCAGCCC  1680
1681  CAGCAGCCTG  GAGCGCCCCC  ACAGCAGGAC  TACACGAAGG  CCTGGGAGGA  GTACTACAAG  1740
1741  AAGCAAGCGC  AAGTGGCCAC  CGGAGGGGGT  CCAGGAGCTC  CCCCAGGCTT  CCTGGCCCCC  1800
1801  CCCATGGTGT  TCGAGCCCCT  CCTCTCTTCC  GCCCTGGCTC  AGCTCCCGCG  GCCCCGCCCG  1860
1861  TCCCCCCTCC  CAGGACTGGT  CTGTTGTCTT  TTCATCTGTT  CAAGAGGAGA  TTGA  1914

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Otg-0463Otolemur garnettii100.00.0 816
LLPS-Pap-0173Pan paniscus100.00.0 805
LLPS-Hos-0368Homo sapiens100.00.0 816
LLPS-Mam-2514Macaca mulatta100.00.0 759
LLPS-Caj-3873Callithrix jacchus100.00.0 816
LLPS-Cea-0833Cercocebus atys100.02e-1068.2
LLPS-Maf-1482Macaca fascicularis100.00.0 803
LLPS-Chs-2513Chlorocebus sabaeus100.00.0 814
LLPS-Mal-3509Mandrillus leucophaeus100.00.0 815
LLPS-Eqc-2764Equus caballus99.650.0 811
LLPS-Sus-0808Sus scrofa99.480.0 815
LLPS-Myl-0632Myotis lucifugus99.480.0 812
LLPS-Ova-3080Ovis aries99.370.0 749
LLPS-Ict-0517Ictidomys tridecemlineatus99.310.0 813
LLPS-Bot-0657Bos taurus99.310.0 814
LLPS-Orc-0331Oryctolagus cuniculus99.040.0 616
LLPS-Sah-0863Sarcophilus harrisii98.750.0 769
LLPS-Mum-2290Mus musculus98.610.0 808
LLPS-Ran-2788Rattus norvegicus98.610.0 809
LLPS-Fec-1707Felis catus98.270.0 811
LLPS-Caf-1525Canis familiaris98.060.0 687
LLPS-Pat-1743Pan troglodytes97.750.0 778
LLPS-Loa-3001Loxodonta africana96.90.0 781
LLPS-Mup-2322Mustela putorius furo96.360.0 806
LLPS-Pes-2987Pelodiscus sinensis96.130.0 733
LLPS-Dio-2882Dipodomys ordii95.880.0 718
LLPS-Gog-0473Gorilla gorilla95.670.0 748
LLPS-Mod-0802Monodelphis domestica94.80.0 744
LLPS-Anc-0771Anolis carolinensis93.730.0 706
LLPS-Paa-3188Papio anubis93.480.0 741
LLPS-Aon-0275Aotus nancymaae92.370.0 718
LLPS-Man-0504Macaca nemestrina91.870.0 786
LLPS-Mea-1310Mesocricetus auratus91.640.0 780
LLPS-Nol-3405Nomascus leucogenys90.990.0 745
LLPS-Ora-1387Ornithorhynchus anatinus90.530.0 729
LLPS-Urm-1240Ursus maritimus89.670.0 683
LLPS-Cap-1207Cavia porcellus89.220.0 795
LLPS-Rhb-4002Rhinopithecus bieti87.960.0 696
LLPS-Leo-2827Lepisosteus oculatus81.620.0 596
LLPS-Gaa-1855Gasterosteus aculeatus78.180.0 594
LLPS-Orn-2838Oreochromis niloticus77.340.0 584
LLPS-Fud-2900Fukomys damarensis77.213e-168 498
LLPS-Lac-1015Latimeria chalumnae77.10.0 599
LLPS-Scf-3635Scleropages formosus75.820.0 592
LLPS-Xim-0770Xiphophorus maculatus75.04e-0654.3
LLPS-Scm-1760Scophthalmus maximus74.290.0 547
LLPS-Icp-0467Ictalurus punctatus73.840.0 547
LLPS-Dar-0659Danio rerio72.650.0 562
LLPS-Xet-1034Xenopus tropicalis71.431e-0655.8
LLPS-Asm-3281Astyanax mexicanus70.10.0 580
LLPS-Pof-0258Poecilia formosa69.910.0 538
LLPS-Gaga-2936Gallus gallus67.231e-171 511
LLPS-Meg-1770Meleagris gallopavo66.753e-170 506
LLPS-Tut-1504Tursiops truncatus66.118e-169 504
LLPS-Fia-3292Ficedula albicollis66.021e-169 506
LLPS-Anp-1411Anas platyrhynchos66.023e-170 506
LLPS-Ten-1008Tetraodon nigroviridis65.953e-169 505
LLPS-Tag-2316Taeniopygia guttata65.083e-167 499
LLPS-Orl-0007Oryzias latipes64.971e-168 504
LLPS-Cas-3470Carlito syrichta64.581e-162 488
LLPS-Aim-1783Ailuropoda melanoleuca62.647e-164 492
LLPS-Tar-1729Takifugu rubripes60.776e-153 465
LLPS-Amt-0212Amborella trichopoda41.12e-0655.1
LLPS-Cis-1743Ciona savignyi38.914e-29 123
LLPS-Phv-2071Phaseolus vulgaris38.575e-0653.9
LLPS-Via-0660Vigna angularis38.574e-0654.3
LLPS-Mae-0788Manihot esculenta38.242e-0654.7
LLPS-Viv-0370Vitis vinifera36.998e-0653.1
LLPS-Drm-0897Drosophila melanogaster36.467e-50 189
LLPS-Orr-2420Oryza rufipogon36.425e-2099.0
LLPS-Brr-2072Brassica rapa36.266e-1892.0
LLPS-Brn-2590Brassica napus36.261e-1892.0
LLPS-Orp-1495Oryza punctata35.963e-21 102
LLPS-Cogr-0338Colletotrichum graminicola35.963e-1480.1
LLPS-Arl-2274Arabidopsis lyrata35.878e-1788.6
LLPS-Prp-0594Prunus persica35.83e-1892.8
LLPS-Bro-0743Brassica oleracea35.719e-1891.3
LLPS-Php-0781Physcomitrella patens35.718e-0653.1
LLPS-Lem-1422Leptosphaeria maculans35.636e-0756.6
LLPS-Glm-1170Glycine max35.533e-0654.3
LLPS-Org-1036Oryza glaberrima35.399e-21 100
LLPS-Orni-1381Oryza nivara35.399e-21 100
LLPS-Orb-0692Oryza barthii35.391e-20 100
LLPS-Ori-0477Oryza indica35.399e-21 100
LLPS-Orgl-1279Oryza glumaepatula35.396e-21 102
LLPS-Nia-1166Nicotiana attenuata35.234e-1892.8
LLPS-Cus-1809Cucumis sativus35.169e-2097.8
LLPS-Sot-0217Solanum tuberosum34.911e-1894.4
LLPS-Mua-1313Musa acuminata34.884e-22 105
LLPS-Orbr-0902Oryza brachyantha34.831e-20 100
LLPS-Sol-2009Solanum lycopersicum34.668e-1892.0
LLPS-Zem-1266Zea mays34.656e-1376.3
LLPS-Pytr-0650Pyrenophora triticirepentis34.522e-0655.1
LLPS-Pot-0982Populus trichocarpa34.54e-1789.4
LLPS-Dac-0845Daucus carota34.54e-1892.8
LLPS-Gor-0721Gossypium raimondii34.382e-1687.4
LLPS-Brd-1049Brachypodium distachyon34.329e-1891.7
LLPS-Hea-0870Helianthus annuus34.135e-1892.0
LLPS-Sei-1409Setaria italica34.087e-1789.0
LLPS-Mao-0361Magnaporthe oryzae34.072e-1480.5
LLPS-Tru-1413Triticum urartu33.736e-1789.0
LLPS-Tra-2270Triticum aestivum33.732e-1687.4
LLPS-Thc-0143Theobroma cacao33.718e-1788.6
LLPS-Hov-1835Hordeum vulgare33.331e-1687.8
LLPS-Met-0178Medicago truncatula32.974e-1789.0
LLPS-Lep-1022Leersia perrieri32.961e-1791.3
LLPS-Blg-0635Blumeria graminis32.711e-0655.8
LLPS-Gas-0344Galdieria sulphuraria30.272e-1274.3
LLPS-Pyt-1558Pyrenophora teres29.743e-25 114
LLPS-Chr-0017Chlamydomonas reinhardtii29.181e-1686.7
LLPS-Coo-0895Colletotrichum orbiculare28.955e-21 101
LLPS-Trv-0092Trichoderma virens28.937e-22 103
LLPS-Osl-0813Ostreococcus lucimarinus28.686e-1889.4
LLPS-Gag-1396Gaeumannomyces graminis28.628e-1994.7
LLPS-Scs-0954Sclerotinia sclerotiorum27.927e-2097.8
LLPS-Map-0084Magnaporthe poae27.683e-1994.7
LLPS-Zyt-0880Zymoseptoria tritici27.33e-21 103