LLPS-Poa-3005
HOXD9
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Homeobox protein |
| Gene Name: | HOXD9 |
| Ensembl Gene: | ENSPPYG00000012959.2 |
| Ensembl Protein: | ENSPPYP00000014473.2 |
| Organism: | Pongo abelii |
| Taxa ID: | 9601 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPPYT00000015060.2 | ENSPPYP00000014473.2 |
| UniProt | H2P7X5, H2P7X5_PONAB | |
| GeneBank | ABGA01155000, ABGA01154999 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSSSGTLSNY YVDSLIGHEG DEVFAARFGP PGPSAQGRPA GVADSPAATA AEFASCSFAP 60 61 KSAVFSASWS AVPAQPPAAA AMSGLYHPYV PPPPLAASAS DPGRYVRSWM EPLPGFPGGA 120 121 GGGGGGSSST SLSSSSKRTE CSAARESQGS SGPEFSCNSF LRDKAAAATG GTGPGAGIGA 180 181 ATGTGGSSEP SACSDHPSPG CPLKEEEKQH SQPQQQQLDP NNPAANWIHA RSTRKKRCPY 240 241 TKYQTLELEK EFLFNMYLTR DRRYEVARIL NLTERQVKIW FQNRRMKMKK MSKEKCPKGD 300 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCTTCCA GTGGCACCCT CAGCAACTAC TACGTGGACT CGCTTATAGG CCATGAGGGC 60 61 GACGAGGTGT TCGCGGCGCG CTTCGGGCCG CCGGGGCCAA GCGCGCAAGG CCGGCCTGCA 120 121 GGTGTGGCTG ATAGCCCGGC CGCCACCGCC GCCGAGTTCG CCTCGTGTAG TTTTGCCCCC 180 181 AAATCGGCCG TGTTCTCTGC CTCGTGGTCC GCGGTGCCCG CCCAGCCCCC AGCAGCTGCA 240 241 GCGATGAGCG GCCTCTACCA CCCGTATGTT CCCCCGCCGC CCCTGGCCGC CTCTGCCTCC 300 301 GATCCCGGCC GCTACGTGCG CTCCTGGATG GAGCCGCTGC CCGGCTTCCC GGGCGGTGCG 360 361 GGCGGTGGCG GTGGCGGTTC CTCCTCCACT TCCTTATCCT CCTCCTCCAA ACGGACTGAG 420 421 TGCTCCGCGG CCCGGGAGTC CCAGGGGAGC AGCGGCCCCG AGTTCTCGTG CAACTCGTTC 480 481 CTGCGGGACA AGGCGGCAGC GGCGACAGGG GGAACCGGGC CTGGGGCAGG GATCGGGGCC 540 541 GCGACTGGGA CGGGCGGCTC GTCGGAGCCC TCAGCTTGCA GCGACCACCC AAGCCCGGGC 600 601 TGTCCGCTGA AGGAGGAGGA GAAGCAGCAT TCGCAGCCGC AGCAGCAGCA ACTTGACCCA 660 661 AACAACCCCG CAGCGAACTG GATCCACGCT CGCTCCACCC GGAAAAAGCG CTGTCCCTAC 720 721 ACCAAATACC AGACGCTTGA GCTGGAGAAA GAATTCCTCT TCAACATGTA CCTCACGCGG 780 781 GACCGGCGCT ACGAGGTGGC CAGGATTCTC AACCTAACAG AGAGACAGGT CAAAATCTGG 840 841 TTTCAGAACC GTAGGATGAA AATGAAAAAG ATGAGCAAGG AGAAATGCCC CAAAGGAGAC 900 901 TGA 903 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Nucleolus | |
Molecular Function | DNA-binding transcription repressor activity, RNA polymerase II-specific | |
Molecular Function | RNA polymerase II regulatory region sequence-specific DNA binding | |
Biological Process | Adult locomotory behavior | |
Biological Process | Anterior/posterior pattern specification | |
Biological Process | Embryonic forelimb morphogenesis | |
Biological Process | Embryonic skeletal system morphogenesis | |
Biological Process | Hindlimb morphogenesis | |
Biological Process | Mammary gland development | |
Biological Process | Peripheral nervous system neuron development | |
Biological Process | Positive regulation of transcription by RNA polymerase II | |
Biological Process | Proximal/distal pattern formation | |
Biological Process | Single fertilization | |
Biological Process | Skeletal muscle tissue development | |
Biological Process | Transcription, DNA-templated |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Man-3914 | Macaca nemestrina | 100.0 | 3e-73 | 236 |
| LLPS-Maf-1245 | Macaca fascicularis | 100.0 | 3e-73 | 235 |
| LLPS-Chs-2017 | Chlorocebus sabaeus | 100.0 | 3e-73 | 235 |
| LLPS-Ora-2732 | Ornithorhynchus anatinus | 100.0 | 2e-38 | 144 |
| LLPS-Rhb-1367 | Rhinopithecus bieti | 99.33 | 3e-73 | 236 |
| LLPS-Paa-2520 | Papio anubis | 99.33 | 7e-73 | 235 |
| LLPS-Mal-0138 | Mandrillus leucophaeus | 99.33 | 9e-74 | 232 |
| LLPS-Cea-4713 | Cercocebus atys | 99.33 | 1e-72 | 234 |
| LLPS-Pat-4270 | Pan troglodytes | 97.99 | 1e-71 | 232 |
| LLPS-Ova-4293 | Ovis aries | 97.98 | 2e-58 | 190 |
| LLPS-Caj-4595 | Callithrix jacchus | 97.35 | 2e-39 | 147 |
| LLPS-Aon-4175 | Aotus nancymaae | 97.35 | 2e-39 | 147 |
| LLPS-Nol-4637 | Nomascus leucogenys | 97.19 | 6e-128 | 374 |
| LLPS-Anc-2563 | Anolis carolinensis | 97.06 | 6e-42 | 147 |
| LLPS-Ten-0275 | Tetraodon nigroviridis | 97.06 | 7e-40 | 146 |
| LLPS-Asm-3686 | Astyanax mexicanus | 97.06 | 8e-41 | 148 |
| LLPS-Dar-4018 | Danio rerio | 96.92 | 5e-38 | 141 |
| LLPS-Scm-3326 | Scophthalmus maximus | 96.92 | 6e-38 | 140 |
| LLPS-Orl-0165 | Oryzias latipes | 96.92 | 6e-38 | 140 |
| LLPS-Gog-0127 | Gorilla gorilla | 96.67 | 6e-69 | 224 |
| LLPS-Hos-3623 | Homo sapiens | 96.64 | 5e-70 | 227 |
| LLPS-Dio-3014 | Dipodomys ordii | 95.59 | 2e-39 | 145 |
| LLPS-Scf-1585 | Scleropages formosus | 95.59 | 3e-40 | 147 |
| LLPS-Fec-2672 | Felis catus | 95.58 | 6e-39 | 145 |
| LLPS-Bot-0808 | Bos taurus | 95.58 | 2e-38 | 144 |
| LLPS-Cas-3939 | Carlito syrichta | 95.16 | 4e-35 | 132 |
| LLPS-Anp-2726 | Anas platyrhynchos | 95.16 | 2e-35 | 134 |
| LLPS-Mup-2366 | Mustela putorius furo | 94.69 | 2e-38 | 144 |
| LLPS-Xet-0362 | Xenopus tropicalis | 94.12 | 3e-39 | 144 |
| LLPS-Ict-3341 | Ictidomys tridecemlineatus | 94.12 | 2e-39 | 145 |
| LLPS-Pes-1859 | Pelodiscus sinensis | 94.12 | 5e-40 | 143 |
| LLPS-Meg-2757 | Meleagris gallopavo | 94.12 | 2e-40 | 144 |
| LLPS-Fud-0652 | Fukomys damarensis | 94.12 | 4e-39 | 143 |
| LLPS-Loa-1750 | Loxodonta africana | 93.85 | 2e-36 | 138 |
| LLPS-Cap-1146 | Cavia porcellus | 92.92 | 2e-39 | 147 |
| LLPS-Eqc-3782 | Equus caballus | 92.65 | 3e-38 | 142 |
| LLPS-Icp-1530 | Ictalurus punctatus | 91.18 | 3e-37 | 138 |
| LLPS-Orc-3126 | Oryctolagus cuniculus | 90.2 | 2e-21 | 95.5 |
| LLPS-Otg-0124 | Otolemur garnettii | 89.83 | 2e-39 | 147 |
| LLPS-Ere-0467 | Erinaceus europaeus | 89.26 | 8e-70 | 226 |
| LLPS-Tut-1524 | Tursiops truncatus | 88.59 | 6e-60 | 197 |
| LLPS-Mod-3639 | Monodelphis domestica | 88.06 | 1e-35 | 134 |
| LLPS-Myl-3441 | Myotis lucifugus | 88.06 | 8e-36 | 135 |
| LLPS-Sah-4030 | Sarcophilus harrisii | 88.06 | 1e-35 | 134 |
| LLPS-Orn-3410 | Oreochromis niloticus | 86.76 | 2e-36 | 137 |
| LLPS-Pof-2749 | Poecilia formosa | 86.76 | 2e-36 | 136 |
| LLPS-Xim-2420 | Xiphophorus maculatus | 86.76 | 2e-36 | 136 |
| LLPS-Tar-3386 | Takifugu rubripes | 86.76 | 2e-36 | 137 |
| LLPS-Mum-1829 | Mus musculus | 85.91 | 1e-70 | 228 |
| LLPS-Mea-1098 | Mesocricetus auratus | 85.33 | 8e-70 | 226 |
| LLPS-Pap-3995 | Pan paniscus | 83.87 | 6e-118 | 349 |
| LLPS-Sus-2013 | Sus scrofa | 83.77 | 8e-113 | 336 |
| LLPS-Ran-0965 | Rattus norvegicus | 82.67 | 5e-63 | 209 |
| LLPS-Mam-2560 | Macaca mulatta | 79.03 | 2e-27 | 114 |
| LLPS-Urm-2964 | Ursus maritimus | 71.93 | 4e-18 | 84.3 |
| LLPS-Drm-0132 | Drosophila melanogaster | 71.7 | 1e-17 | 86.3 |
| LLPS-Gaga-0291 | Gallus gallus | 68.85 | 8e-18 | 84.7 |
| LLPS-Aim-0510 | Ailuropoda melanoleuca | 68.85 | 3e-18 | 85.9 |
| LLPS-Gaa-1892 | Gasterosteus aculeatus | 68.85 | 4e-18 | 85.9 |
| LLPS-Cae-1525 | Caenorhabditis elegans | 67.86 | 3e-19 | 89.4 |
| LLPS-Tag-1825 | Taeniopygia guttata | 67.21 | 8e-18 | 84.7 |
| LLPS-Caf-3102 | Canis familiaris | 63.93 | 1e-17 | 84.0 |
| LLPS-Leo-2545 | Lepisosteus oculatus | 53.95 | 6e-72 | 229 |
| LLPS-Lac-3385 | Latimeria chalumnae | 52.05 | 1e-67 | 218 |
| LLPS-Fia-1148 | Ficedula albicollis | 48.98 | 2e-18 | 85.9 |