• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Poa-1587
KPNA3

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Importin subunit alpha
Gene Name: KPNA3
Ensembl Gene: ENSPPYG00000005372.2
Ensembl Protein: ENSPPYP00000006120.2
Organism: Pongo abelii
Taxa ID: 9601
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear pore complex, Nucleolus, Stress granulePredicted from orthologs(View)

▼ FUNCTION

Functions in nuclear protein import.

▼ SEQUENCE

Protein Sequence (FASTA)
1     TMRRHRNEVT  VELRKNKRDE  HLLKKRNVPQ  EESLEDSDVD  ADFKAQNVTL  EAILQNATSD  60
61    NPVVQLSAVQ  AARKLLSSDR  NPPIDDLIKS  GILPILVKCL  ERDDNPSLQF  EAAWALTNIA  120
121   SGTSAQTQAV  VQSNAVPLFL  RLLHSPHQNV  CEDGPQCRDY  VISLGVVKPL  LSFINPSIPI  180
181   TFLRNVTWVI  VNLCRNKDPP  PPMETVQEIL  PALCVLIYHT  DINILVDTVW  ALSYLTDGGN  240
241   EQIQMVIDSG  VVPFLVPLLS  HQEVKVQTAA  LRAVGNIVTG  TDEQTQVVLN  CDVLSHFPNL  300
301   LSHPKEKINK  EAVWFLSNIT  AGNQQQVQAV  IDAGLIPMII  HQLAKGDFGT  QKEAAWAISN  360
361   LTISGRKDQV  EYLVQQNVIP  PFCNLLSVKD  SQVVQVVLDG  LKNILIMAGD  EASTIAEIIE  420
421   ECGGLEKIEV  LQQHENEDIY  KLAFEIIDQY  FSGDDIDEDP  CLIPEATQGG  TYNFDPTANL  480
481   QTKEFNF  487
Nucleotide CDS Sequence (FASTA)
1     ACAATGCGAA  GACATAGAAA  TGAAGTGACA  GTGGAACTGC  GGAAGAACAA  AAGAGATGAA  60
61    CACTTATTGA  AAAAGAGAAA  TGTTCCCCAA  GAAGAAAGTC  TAGAAGATTC  AGATGTTGAT  120
121   GCTGATTTTA  AAGCACAAAA  TGTAACCCTA  GAAGCTATAT  TGCAGAATGC  CACAAGTGAT  180
181   AACCCAGTGG  TCCAATTGAG  TGCTGTCCAG  GCAGCAAGAA  AACTGTTATC  CAGTGACAGA  240
241   AATCCACCGA  TTGATGACTT  AATAAAATCT  GGGATTTTAC  CAATTCTAGT  CAAATGTCTA  300
301   GAAAGGGATG  ATAATCCTTC  ATTACAGTTT  GAAGCTGCTT  GGGCATTAAC  TAACATAGCA  360
361   TCAGGAACTT  CTGCACAGAC  TCAAGCTGTT  GTGCAGTCTA  ATGCAGTACC  TCTTTTTCTG  420
421   AGACTTCTTC  ATTCACCACA  TCAGAATGTT  TGTGAAGATG  GTCCTCAATG  TAGAGATTAT  480
481   GTCATATCAC  TGGGAGTTGT  CAAACCTCTT  CTGTCCTTCA  TCAATCCCTC  CATCCCCATC  540
541   ACCTTCCTTC  GGAACGTCAC  ATGGGTCATT  GTCAATCTCT  GCAGGAATAA  GGATCCCCCA  600
601   CCGCCTATGG  AGACAGTTCA  GGAGATTTTG  CCAGCTTTAT  GTGTCCTCAT  ATACCATACG  660
661   GATATAAACA  TTCTCGTAGA  CACTGTTTGG  GCTCTGTCAT  ACTTGACAGA  TGGAGGTAAT  720
721   GAGCAGATAC  AGATGGTTAT  TGATTCAGGA  GTTGTGCCAT  TTCTTGTGCC  CCTTCTGAGC  780
781   CATCAGGAAG  TCAAAGTTCA  AACAGCAGCC  CTCAGAGCAG  TTGGCAACAT  AGTGACTGGC  840
841   ACCGACGAGC  AGACCCAGGT  TGTTCTCAAT  TGTGATGTCC  TGTCACACTT  CCCAAATCTC  900
901   TTATCACACC  CAAAAGAGAA  GATAAATAAG  GAAGCAGTGT  GGTTCCTTTC  CAACATAACA  960
961   GCAGGCAACC  AGCAACAAGT  TCAAGCTGTA  ATAGATGCTG  GATTAATTCC  TATGATTATT  1020
1021  CATCAGCTTG  CTAAGGGGGA  CTTTGGAACA  CAAAAAGAAG  CTGCTTGGGC  AATCAGCAAC  1080
1081  TTAACAATAA  GTGGCAGAAA  AGATCAGGTT  GAGTACCTTG  TACAGCAGAA  TGTAATACCA  1140
1141  CCGTTCTGTA  ATTTACTGTC  AGTGAAAGAT  TCTCAAGTGG  TTCAGGTGGT  TCTAGATGGT  1200
1201  CTAAAAAACA  TTCTGATAAT  GGCCGGTGAT  GAAGCAAGCA  CAATAGCTGA  AATAATAGAG  1260
1261  GAATGTGGAG  GTTTGGAGAA  AATTGAAGTT  TTACAGCAAC  ATGAAAACGA  AGACATATAT  1320
1321  AAATTAGCAT  TTGAAATCAT  AGATCAGTAT  TTCTCTGGTG  ATGATATTGA  TGAAGATCCC  1380
1381  TGCCTCATTC  CTGAAGCAAC  ACAAGGAGGT  ACTTACAATT  TTGATCCAAC  AGCCAACCTT  1440
1441  CAAACAAAAG  AATTTAATTT  TTAA  1464

▼ KEYWORD

ID
Family
Complete proteome
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Nucleus
Molecular Function
Nuclear import signal receptor activity
Molecular Function
Protein C-terminus binding
Molecular Function
Protein transporter activity
Biological Process
Protein import into nucleus

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Paa-0021Papio anubis97.790.0 986
LLPS-Maf-2225Macaca fascicularis97.790.0 986
LLPS-Caj-2639Callithrix jacchus97.790.0 986
LLPS-Mam-0902Macaca mulatta97.790.0 986
LLPS-Man-1057Macaca nemestrina97.790.0 986
LLPS-Nol-1985Nomascus leucogenys97.720.0 954
LLPS-Chs-2809Chlorocebus sabaeus97.710.0 949
LLPS-Tut-0366Tursiops truncatus97.590.0 983
LLPS-Bot-4161Bos taurus97.590.0 983
LLPS-Dio-3070Dipodomys ordii97.590.0 982
LLPS-Ran-1626Rattus norvegicus97.590.0 983
LLPS-Mup-2845Mustela putorius furo97.590.0 981
LLPS-Aim-1433Ailuropoda melanoleuca97.590.0 983
LLPS-Ova-0860Ovis aries97.590.0 983
LLPS-Mum-1091Mus musculus97.590.0 983
LLPS-Aon-1819Aotus nancymaae97.590.0 984
LLPS-Sus-0132Sus scrofa97.590.0 983
LLPS-Caf-1642Canis familiaris97.590.0 981
LLPS-Ict-2904Ictidomys tridecemlineatus97.590.0 983
LLPS-Fec-0503Felis catus97.590.0 983
LLPS-Urm-0959Ursus maritimus97.590.0 981
LLPS-Loa-0697Loxodonta africana97.590.0 983
LLPS-Orc-1200Oryctolagus cuniculus97.590.0 982
LLPS-Eqc-1570Equus caballus97.390.0 982
LLPS-Pat-1072Pan troglodytes97.390.0 982
LLPS-Pap-1834Pan paniscus97.390.0 982
LLPS-Hos-0564Homo sapiens97.390.0 982
LLPS-Otg-0194Otolemur garnettii97.390.0 982
LLPS-Rhb-0329Rhinopithecus bieti97.390.0 983
LLPS-Myl-1049Myotis lucifugus97.380.0 980
LLPS-Gog-3920Gorilla gorilla97.310.0 950
LLPS-Fud-0107Fukomys damarensis97.190.0 981
LLPS-Cap-1408Cavia porcellus97.190.0 981
LLPS-Sah-2491Sarcophilus harrisii96.790.0 974
LLPS-Gaga-0023Gallus gallus96.590.0 979
LLPS-Mod-0400Monodelphis domestica96.590.0 979
LLPS-Tag-0294Taeniopygia guttata96.390.0 976
LLPS-Meg-0528Meleagris gallopavo96.390.0 976
LLPS-Fia-1408Ficedula albicollis96.380.0 974
LLPS-Ora-0178Ornithorhynchus anatinus96.050.0 934
LLPS-Anc-0626Anolis carolinensis96.050.0 939
LLPS-Cea-1956Cercocebus atys95.770.0 959
LLPS-Mal-0047Mandrillus leucophaeus95.180.0 958
LLPS-Icp-0218Ictalurus punctatus95.180.0 964
LLPS-Lac-0622Latimeria chalumnae95.180.0 963
LLPS-Anp-0644Anas platyrhynchos95.050.0 926
LLPS-Scf-3520Scleropages formosus94.780.0 960
LLPS-Ere-0115Erinaceus europaeus94.40.0 756
LLPS-Xim-2674Xiphophorus maculatus94.380.0 961
LLPS-Gaa-0618Gasterosteus aculeatus94.180.0 958
LLPS-Pof-1457Poecilia formosa94.00.0 954
LLPS-Dar-3108Danio rerio93.780.0 946
LLPS-Orn-1696Oreochromis niloticus93.640.0 956
LLPS-Orl-0264Oryzias latipes92.770.0 941
LLPS-Leo-1104Lepisosteus oculatus92.220.0 951
LLPS-Scm-0146Scophthalmus maximus92.170.0 935
LLPS-Mea-2350Mesocricetus auratus91.780.0 912
LLPS-Ten-1683Tetraodon nigroviridis90.760.0 918
LLPS-Asm-3316Astyanax mexicanus90.60.0 909
LLPS-Tar-2544Takifugu rubripes90.560.0 914
LLPS-Xet-0150Xenopus tropicalis85.660.0 832
LLPS-Cas-1346Carlito syrichta84.740.0 868
LLPS-Pes-1936Pelodiscus sinensis84.340.0 863
LLPS-Cii-1885Ciona intestinalis72.110.0 703
LLPS-Drm-0105Drosophila melanogaster66.470.0 639
LLPS-Cis-0296Ciona savignyi64.420.0 616
LLPS-Cae-0053Caenorhabditis elegans62.050.0 588
LLPS-Scj-0981Schizosaccharomyces japonicus47.184e-144 431
LLPS-Scc-1122Schizosaccharomyces cryophilus46.813e-142 426
LLPS-Usm-0637Ustilago maydis46.37e-139 418
LLPS-Asn-0636Aspergillus nidulans46.151e-139 420
LLPS-Asfu-0373Aspergillus fumigatus45.876e-139 418
LLPS-Nef-0967Neosartorya fischeri45.878e-139 418
LLPS-Trv-1149Trichoderma virens45.662e-143 430
LLPS-Ast-0980Aspergillus terreus45.522e-140 422
LLPS-Scp-0605Schizosaccharomyces pombe45.248e-140 420
LLPS-Map-0249Magnaporthe poae45.142e-139 420
LLPS-Yal-0529Yarrowia lipolytica45.12e-141 424
LLPS-Trr-0178Trichoderma reesei45.094e-141 424
LLPS-Aso-0120Aspergillus oryzae45.063e-139 419
LLPS-Asf-0705Aspergillus flavus45.063e-139 419