• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Poa-1335
SDAD1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Protein SDA1
Gene Name: SDAD1, CR201_G0024878
Ensembl Gene: ENSPPYG00000014852.2
Ensembl Protein: ENSPPYP00000016585.2
Organism: Pongo abelii
Taxa ID: 9601
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-bodyPredicted from orthologs(View)

▼ FUNCTION

Required for 60S pre-ribosomal subunits export to the cytoplasm.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSSRNNNKLP  SNLPQLQNLI  KRDPPAYIEE  FLQQYNHYKS  NVEIFKLQPN  KPSKELAELV  60
61    MFMAQISHCY  PEYLSNFPQE  VKDLLSCNHT  VLDPDLRMTF  CKALILLRNK  NLINPSSLLE  120
121   LFFELLRCHD  KLLRKTLYTH  IVTDIKNINA  KHKNNKVNVV  LQNFMYTMLR  DSNATAAKMS  180
181   LDVMIELYRR  NIWNDAKTVN  VITTACFSKV  TKMLVAALTF  FLGKDEDEKQ  DSDSESEDDG  240
241   PTARDLLVQY  ATGKKSSKNK  KKLEKAMKVL  KKQKKKKKPE  VFNFSAIHLI  HDPQDFAEKL  300
301   LKQLECCKER  FEVKMMLMNL  ISRLVGIHEL  FLFNFYPFLQ  RFLQPHQREV  TKILLFAAQA  360
361   SHHLVPPEII  QSLLMTVANN  FVTDKNSGEV  MTVGINAIKE  ITARCPLAMT  EELLQDLAQY  420
421   KTHKDKNVMM  SARTLIHLFR  TLNPQMLQKK  FRGKPTEASI  EARVQEYGEL  DAKDYIPGAE  480
481   VLEVEKEENA  ENDEDGWEST  SLSEEEDADG  EWIDVQHSSD  EERQEISKKL  NSMPMEERKA  540
541   KAAAISTSRV  LTQEDFQKIR  MAQMRKELDA  APGKSQKRKY  IEIDSDEEPR  GELLSLRDIE  600
601   RLHKKPKSDK  ETRLATAMAG  KTDRKEFMRK  KTKTNPFSSS  TNKEKKKQKN  FMMMRYSQNV  660
661   RSKNKRSFRE  KQLALRDALL  KKRKRMK  687
Nucleotide CDS Sequence (FASTA)
1     ATGTCCAGCA  GAAACAACAA  CAAGCTGCCC  AGCAACCTGC  CGCAGTTACA  GAATCTAATC  60
61    AAGCGAGACC  CGCCGGCCTA  CATCGAGGAG  TTTCTACAGC  AGTATAATCA  CTACAAATCC  120
121   AATGTGGAGA  TTTTCAAATT  GCAACCAAAT  AAACCCAGCA  AAGAACTAGC  AGAGCTGGTG  180
181   ATGTTTATGG  CACAGATTAG  TCACTGCTAC  CCAGAGTACC  TAAGTAATTT  TCCTCAAGAG  240
241   GTGAAAGATC  TTCTCTCCTG  CAATCATACC  GTATTGGATC  CAGATCTTCG  AATGACATTT  300
301   TGCAAAGCTT  TGATCTTGCT  GAGAAATAAG  AATCTCATCA  ATCCATCAAG  CCTGCTAGAA  360
361   CTCTTCTTTG  AACTTCTTCG  TTGCCATGAT  AAGCTTCTGC  GAAAGACTTT  ATACACACAT  420
421   ATTGTGACTG  ATATCAAGAA  TATAAATGCA  AAACACAAGA  ACAATAAAGT  GAATGTAGTA  480
481   TTGCAAAATT  TCATGTACAC  CATGTTAAGA  GATAGCAATG  CAACCGCAGC  CAAGATGTCT  540
541   TTAGATGTAA  TGATTGAACT  CTACAGAAGG  AACATCTGGA  ATGATGCCAA  AACTGTCAAT  600
601   GTTATCACAA  CTGCATGCTT  CTCTAAGGTC  ACCAAGATGT  TAGTTGCCGC  TTTGACATTC  660
661   TTTCTTGGGA  AAGATGAAGA  TGAAAAACAG  GACAGTGACT  CCGAATCTGA  GGATGATGGA  720
721   CCAACAGCAA  GAGACCTGCT  AGTACAATAT  GCTACAGGGA  AGAAAAGTTC  CAAAAACAAG  780
781   AAAAAGTTGG  AAAAGGCAAT  GAAAGTACTC  AAGAAACAAA  AAAAGAAGAA  AAAACCAGAG  840
841   GTGTTTAACT  TTTCAGCCAT  TCACTTGATT  CATGATCCCC  AAGATTTTGC  GGAAAAACTA  900
901   CTAAAGCAGC  TTGAGTGCTG  TAAGGAGAGG  TTTGAAGTGA  AGATGATGCT  CATGAACCTC  960
961   ATCTCCAGAT  TGGTGGGAAT  TCATGAGCTT  TTCCTCTTCA  ATTTCTATCC  CTTTTTGCAA  1020
1021  AGGTTTCTGC  AGCCCCACCA  AAGAGAAGTA  ACAAAGATCC  TTCTGTTTGC  TGCACAAGCA  1080
1081  TCTCATCACC  TAGTACCCCC  AGAGATTATT  CAATCATTGC  TTATGACTGT  GGCAAACAAT  1140
1141  TTTGTTACCG  ACAAGAACTC  TGGAGAAGTC  ATGACAGTAG  GAATCAATGC  TATAAAGGAG  1200
1201  ATAACAGCTC  GATGTCCTCT  GGCCATGACT  GAAGAACTTC  TCCAAGACCT  GGCTCAGTAT  1260
1261  AAAACACACA  AGGATAAGAA  TGTAATGATG  TCTGCTAGAA  CTTTGATTCA  CCTCTTCCGA  1320
1321  ACACTGAATC  CTCAGATGCT  GCAGAAGAAA  TTCCGGGGTA  AGCCTACAGA  GGCCTCCATA  1380
1381  GAAGCAAGAG  TACAAGAATA  TGGAGAATTA  GATGCTAAAG  ATTACATTCC  AGGAGCAGAA  1440
1441  GTTCTGGAAG  TTGAGAAAGA  AGAGAATGCT  GAAAATGATG  AAGATGGATG  GGAAAGTACG  1500
1501  AGTCTCAGTG  AGGAGGAGGA  TGCTGATGGC  GAATGGATTG  ATGTGCAACA  CTCTTCTGAT  1560
1561  GAAGAACGGC  AAGAAATCTC  CAAGAAGCTG  AACAGCATGC  CCATGGAGGA  GCGGAAAGCC  1620
1621  AAAGCTGCAG  CCATCAGCAC  CAGCCGAGTT  TTAACTCAGG  AAGACTTCCA  GAAAATCCGC  1680
1681  ATGGCCCAAA  TGAGAAAAGA  ACTTGATGCT  GCCCCTGGGA  AATCCCAGAA  GAGGAAATAC  1740
1741  ATTGAAATAG  ACAGTGATGA  AGAGCCCAGG  GGTGAATTAC  TTTCTCTTCG  GGACATTGAA  1800
1801  CGCCTTCATA  AAAAGCCAAA  GTCTGACAAA  GAGACAAGAC  TAGCAACTGC  AATGGCTGGA  1860
1861  AAGACAGACC  GAAAAGAATT  TATGAGGAAG  AAAACCAAAA  CAAATCCATT  TTCCAGTTCG  1920
1921  ACAAATAAAG  AGAAGAAAAA  ACAGAAGAAC  TTTATGATGA  TGCGGTATAG  CCAGAATGTC  1980
1981  CGGTCAAAAA  ATAAGCGTTC  CTTCCGAGAA  AAACAGTTGG  CGCTACGAGA  TGCACTTTTG  2040
2041  AAAAAGAGAA  AAAGAATGAA  GTAA  2064

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Nucleus
Protein transport
Reference proteome
Ribosome biogenesis
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleolus
Biological Process
Actin cytoskeleton organization
Biological Process
Ribosomal large subunit biogenesis
Biological Process
Ribosomal large subunit export from nucleus

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Hos-2307Homo sapiens99.250.01179
LLPS-Pap-2047Pan paniscus99.250.01179
LLPS-Pat-2449Pan troglodytes99.250.01179
LLPS-Gog-1052Gorilla gorilla98.810.01173
LLPS-Caj-2409Callithrix jacchus98.660.01175
LLPS-Chs-2381Chlorocebus sabaeus98.462e-49 174
LLPS-Man-1982Macaca nemestrina97.760.01148
LLPS-Mal-3134Mandrillus leucophaeus97.760.01149
LLPS-Paa-2639Papio anubis97.620.01147
LLPS-Maf-0140Macaca fascicularis97.620.01147
LLPS-Mam-2475Macaca mulatta97.470.01147
LLPS-Aon-0262Aotus nancymaae97.470.01151
LLPS-Rhb-1586Rhinopithecus bieti95.980.01149
LLPS-Fec-2214Felis catus95.670.01143
LLPS-Cea-1537Cercocebus atys95.380.01115
LLPS-Eqc-1277Equus caballus94.930.01137
LLPS-Sus-2383Sus scrofa94.930.01134
LLPS-Orc-1790Oryctolagus cuniculus94.790.01113
LLPS-Aim-3075Ailuropoda melanoleuca94.630.01136
LLPS-Fud-1987Fukomys damarensis94.630.01098
LLPS-Otg-0676Otolemur garnettii94.340.01100
LLPS-Cas-0305Carlito syrichta94.330.01121
LLPS-Ict-2193Ictidomys tridecemlineatus94.293e-28 114
LLPS-Loa-2036Loxodonta africana94.210.01126
LLPS-Mup-2330Mustela putorius furo94.180.01132
LLPS-Ova-0283Ovis aries93.890.01130
LLPS-Mea-0618Mesocricetus auratus93.730.01028
LLPS-Myl-2321Myotis lucifugus93.590.01122
LLPS-Mum-0643Mus musculus93.580.01095
LLPS-Ran-3881Rattus norvegicus93.430.01097
LLPS-Nol-0978Nomascus leucogenys92.480.0 878
LLPS-Urm-1430Ursus maritimus92.10.01080
LLPS-Bot-1148Bos taurus92.10.01128
LLPS-Cap-3050Cavia porcellus91.220.01045
LLPS-Dio-0424Dipodomys ordii91.160.0 989
LLPS-Mod-0568Monodelphis domestica88.810.01063
LLPS-Caf-1030Canis familiaris88.110.01087
LLPS-Sah-1069Sarcophilus harrisii87.50.01047
LLPS-Pes-3118Pelodiscus sinensis84.850.0 970
LLPS-Anc-2755Anolis carolinensis83.160.0 989
LLPS-Tag-2252Taeniopygia guttata82.960.0 993
LLPS-Asm-0633Astyanax mexicanus82.90.0 604
LLPS-Fia-0688Ficedula albicollis82.670.0 991
LLPS-Gaga-2654Gallus gallus82.620.01019
LLPS-Meg-0854Meleagris gallopavo82.470.01014
LLPS-Anp-0020Anas platyrhynchos81.660.0 944
LLPS-Xet-0411Xenopus tropicalis78.120.0 879
LLPS-Scf-2965Scleropages formosus77.650.0 924
LLPS-Icp-0950Ictalurus punctatus76.820.0 912
LLPS-Ten-2736Tetraodon nigroviridis76.750.0 930
LLPS-Dar-2076Danio rerio76.570.0 913
LLPS-Ora-0473Ornithorhynchus anatinus75.896e-91 290
LLPS-Orn-3219Oreochromis niloticus75.860.0 888
LLPS-Xim-1811Xiphophorus maculatus75.670.0 900
LLPS-Pof-0169Poecilia formosa75.070.0 918
LLPS-Tar-0770Takifugu rubripes75.070.0 923
LLPS-Scm-0262Scophthalmus maximus74.180.0 898
LLPS-Gaa-0382Gasterosteus aculeatus73.510.0 904
LLPS-Leo-1660Lepisosteus oculatus67.160.0 776
LLPS-Cii-1037Ciona intestinalis56.460.0 655
LLPS-Cis-0649Ciona savignyi53.860.0 645
LLPS-Cae-0236Caenorhabditis elegans52.03e-59 219
LLPS-Prp-1213Prunus persica50.791e-55 208
LLPS-Sot-0355Solanum tuberosum50.263e-56 210
LLPS-Sol-0291Solanum lycopersicum50.01e-54 204
LLPS-Cus-0697Cucumis sativus49.741e-54 205
LLPS-Thc-0690Theobroma cacao48.949e-53 199
LLPS-Phv-0639Phaseolus vulgaris48.723e-55 207
LLPS-Amt-1534Amborella trichopoda48.411e-34 141
LLPS-Met-0086Medicago truncatula48.211e-56 211
LLPS-Coc-0643Corchorus capsularis47.941e-53 202
LLPS-Glm-1036Glycine max47.943e-53 201
LLPS-Pot-1592Populus trichocarpa47.691e-53 202
LLPS-Viv-0325Vitis vinifera47.451e-54 205
LLPS-Nia-0636Nicotiana attenuata47.396e-56 209
LLPS-Org-0444Oryza glaberrima47.183e-53 201
LLPS-Orr-0808Oryza rufipogon47.185e-54 203
LLPS-Ors-0629Oryza sativa47.189e-55 202
LLPS-Orgl-1175Oryza glumaepatula47.183e-53 201
LLPS-Orni-1297Oryza nivara47.183e-53 201
LLPS-Hea-0158Helianthus annuus47.182e-54 204
LLPS-Orb-1898Oryza barthii47.183e-53 201
LLPS-Php-0972Physcomitrella patens47.092e-53 201
LLPS-Drm-0816Drosophila melanogaster47.070.0 547
LLPS-Mae-1883Manihot esculenta46.914e-53 200
LLPS-Gor-0909Gossypium raimondii46.911e-52 199
LLPS-Orm-1219Oryza meridionalis46.673e-53 203
LLPS-Orbr-0722Oryza brachyantha46.675e-53 200
LLPS-Orp-0637Oryza punctata46.673e-53 201
LLPS-Hov-0588Hordeum vulgare46.672e-53 201
LLPS-Sei-1042Setaria italica46.676e-53 200
LLPS-Tra-1665Triticum aestivum46.672e-53 201
LLPS-Lep-0922Leersia perrieri46.679e-53 199
LLPS-Zem-0119Zea mays46.159e-53 199
LLPS-Brd-0401Brachypodium distachyon46.152e-52 198
LLPS-Sob-0552Sorghum bicolor45.641e-52 199
LLPS-Chr-0518Chlamydomonas reinhardtii43.783e-117 379
LLPS-Bro-1494Brassica oleracea43.39e-44 172
LLPS-Brr-0515Brassica rapa43.31e-43 172
LLPS-Brn-2416Brassica napus43.35e-44 172
LLPS-Ori-0993Oryza indica43.083e-43 171
LLPS-Dac-1186Daucus carota42.354e-48 185
LLPS-Abg-0723Absidia glauca41.91e-138 431
LLPS-Arl-2055Arabidopsis lyrata41.625e-41 164
LLPS-Osl-0919Ostreococcus lucimarinus41.392e-94 312
LLPS-Art-2025Arabidopsis thaliana41.124e-41 164
LLPS-Kop-0408Komagataella pastoris40.564e-82 281
LLPS-Cym-0560Cyanidioschyzon merolae40.05e-35 146
LLPS-Mua-0225Musa acuminata39.744e-33 138
LLPS-Asf-0133Aspergillus flavus39.581e-87 297
LLPS-Aso-0480Aspergillus oryzae39.581e-87 297
LLPS-Pug-0579Puccinia graminis39.082e-31 135
LLPS-Asni-0324Aspergillus niger38.955e-88 298
LLPS-Tru-1130Triticum urartu36.925e-32 136
LLPS-Scj-0475Schizosaccharomyces japonicus36.674e-103 337
LLPS-Put-0951Puccinia triticina36.417e-32 137
LLPS-Asg-1134Ashbya gossypii35.843e-56 209
LLPS-Chc-0789Chondrus crispus35.759e-31 132
LLPS-Tum-0425Tuber melanosporum35.67e-111 359
LLPS-Scp-1013Schizosaccharomyces pombe35.587e-100 329
LLPS-Vir-0901Vigna radiata35.172e-56 209
LLPS-Via-0964Vigna angularis35.049e-26 117
LLPS-Asfu-0768Aspergillus fumigatus34.962e-88 297
LLPS-Ast-0352Aspergillus terreus34.851e-100 332
LLPS-Nef-1386Neosartorya fischeri34.665e-93 311
LLPS-Fus-0572Fusarium solani34.631e-94 315
LLPS-Asc-0666Aspergillus clavatus34.624e-100 330
LLPS-Mao-1014Magnaporthe oryzae34.542e-85 290
LLPS-Asn-1048Aspergillus nidulans34.028e-97 321
LLPS-Coo-1235Colletotrichum orbiculare33.891e-89 302
LLPS-Fuo-0088Fusarium oxysporum33.844e-91 306
LLPS-Scc-0482Schizosaccharomyces cryophilus33.764e-91 305
LLPS-Nec-0384Neurospora crassa33.71e-84 288
LLPS-Sem-0895Selaginella moellendorffii33.672e-28 125
LLPS-Fuv-0059Fusarium verticillioides33.663e-91 306
LLPS-Spr-0637Sporisorium reilianum33.61e-66 241
LLPS-Usm-0568Ustilago maydis33.583e-0757.8
LLPS-Ved-0990Verticillium dahliae33.474e-88 298
LLPS-Cogr-0223Colletotrichum graminicola33.383e-87 295
LLPS-Cog-0778Colletotrichum gloeosporioides33.332e-87 296
LLPS-Gag-0709Gaeumannomyces graminis33.156e-86 292
LLPS-Map-0908Magnaporthe poae33.14e-87 295
LLPS-Pyt-1184Pyrenophora teres32.749e-72 253
LLPS-Yal-0068Yarrowia lipolytica32.626e-98 323
LLPS-Phn-0513Phaeosphaeria nodorum32.512e-75 263
LLPS-Crn-0516Cryptococcus neoformans32.396e-83 285
LLPS-Trv-0323Trichoderma virens32.34e-90 303
LLPS-Sac-0994Saccharomyces cerevisiae32.235e-91 306
LLPS-Dos-0231Dothistroma septosporum32.224e-73 256
LLPS-Pytr-0609Pyrenophora triticirepentis32.192e-71 253
LLPS-Gas-0237Galdieria sulphuraria32.151e-38 155
LLPS-Blg-0765Blumeria graminis32.142e-83 286
LLPS-Trr-1034Trichoderma reesei31.829e-86 292
LLPS-Zyt-0996Zymoseptoria tritici31.395e-76 265
LLPS-Lem-0749Leptosphaeria maculans31.151e-68 245
LLPS-Beb-1461Beauveria bassiana31.08e-85 289
LLPS-Scs-0099Sclerotinia sclerotiorum30.827e-73 256
LLPS-Miv-0292Microbotryum violaceum30.567e-51 194
LLPS-Mel-0043Melampsora laricipopulina30.22e-45 178