• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Php-2464
PHYPA_000779

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Peroxiredoxin
Gene Name: PHYPA_000779, PHYPADRAFT_180517
Ensembl Gene: Pp3c1_17990
Ensembl Protein: Pp3c1_17990V3.4
Organism: Physcomitrella patens
Taxa ID: 3218
LLPS Type: Client


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION


Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

▼ SEQUENCE


Protein Sequence (FASTA)
1     MAPIAVGDTI  PDVTLSYLDD  DNQSQKLSTH  QDLKGKKVML  VAVPGAFTPT  CSQEHVPGFI  60
61    DNAKEIKSKG  VSDIIVVSVN  DPFVMKAWER  SYDGAEHLKF  VADGSLEFTK  ALGLELDLTD  120
121   KGLGVRSRRF  CLLVDDLVVK  VANIEEGGAF  TVSGAEEILK  ALV  163
Nucleotide CDS Sequence (FASTA)
1     ATGGCCCCCA  TTGCAGTGGG  TGATACGATC  CCCGACGTGA  CGCTATCCTA  CTTGGACGAT  60
61    GACAACCAGA  GCCAGAAGCT  CAGCACGCAC  CAGGATTTGA  AAGGCAAGAA  AGTGATGCTT  120
121   GTTGCTGTTC  CTGGCGCATT  CACTCCCACT  TGCAGCCAGG  AACACGTTCC  CGGTTTCATC  180
181   GACAATGCCA  AGGAGATCAA  GAGCAAGGGT  GTGTCGGACA  TCATCGTCGT  CTCAGTGAAT  240
241   GACCCGTTCG  TCATGAAGGC  ATGGGAGCGT  TCCTATGATG  GTGCTGAACA  CCTCAAGTTT  300
301   GTGGCCGATG  GTTCTCTAGA  GTTCACCAAG  GCGTTGGGAT  TGGAGCTGGA  CTTGACCGAC  360
361   AAGGGATTGG  GCGTACGTTC  TCGTAGATTC  TGTCTACTGG  TCGATGACTT  GGTTGTGAAG  420
421   GTTGCGAACA  TTGAGGAAGG  AGGTGCATTC  ACAGTTTCCG  GAGCTGAGGA  AATCTTGAAG  480
481   GCGCTCGTGT  GA  492

▼ KEYWORD


ID
Family
Antioxidant
Complete proteome
Oxidoreductase
Peroxidase
Redox-active center
Reference proteome

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
Thioredoxin peroxidase activity
Biological Process
Cell redox homeostasis
Biological Process
Cellular response to oxidative stress
Biological Process
Hydrogen peroxide catabolic process

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sot-1592Solanum tuberosum69.142e-77 234
LLPS-Sol-2120Solanum lycopersicum67.92e-76 232
LLPS-Nia-1374Nicotiana attenuata67.288e-75 228
LLPS-Art-1134Arabidopsis thaliana67.281e-73 224
LLPS-Zem-0138Zea mays66.671e-75 230
LLPS-Mae-0152Manihot esculenta66.672e-75 229
LLPS-Brr-1181Brassica rapa66.676e-74 226
LLPS-Arl-1234Arabidopsis lyrata66.676e-73 223
LLPS-Bro-2862Brassica oleracea66.054e-73 223
LLPS-Tru-0178Triticum urartu66.056e-76 231
LLPS-Org-1315Oryza glaberrima66.058e-75 228
LLPS-Orm-0810Oryza meridionalis66.058e-75 228
LLPS-Sob-2346Sorghum bicolor66.057e-75 228
LLPS-Gor-2767Gossypium raimondii66.055e-72 221
LLPS-Pot-1478Populus trichocarpa66.051e-72 222
LLPS-Tra-1639Triticum aestivum66.054e-76 231
LLPS-Cus-1863Cucumis sativus66.056e-75 228
LLPS-Orgl-1293Oryza glumaepatula66.058e-75 228
LLPS-Orni-2251Oryza nivara66.058e-75 228
LLPS-Ori-2434Oryza indica66.058e-75 228
LLPS-Brn-1994Brassica napus66.054e-73 223
LLPS-Orb-0832Oryza barthii66.058e-75 228
LLPS-Phv-0077Phaseolus vulgaris65.431e-74 227
LLPS-Viv-1191Vitis vinifera65.431e-72 222
LLPS-Brd-1700Brachypodium distachyon65.432e-74 227
LLPS-Hov-0318Hordeum vulgare65.434e-74 228
LLPS-Prp-1234Prunus persica64.813e-70 216
LLPS-Via-0402Vigna angularis64.812e-73 224
LLPS-Dac-2164Daucus carota64.811e-71 220
LLPS-Glm-1650Glycine max64.815e-74 226
LLPS-Orbr-0268Oryza brachyantha64.22e-72 221
LLPS-Vir-1285Vigna radiata64.21e-72 222
LLPS-Hea-1948Helianthus annuus63.584e-72 221
LLPS-Met-1748Medicago truncatula62.962e-73 224
LLPS-Lep-1874Leersia perrieri60.161e-53 172
LLPS-Thc-1441Theobroma cacao59.881e-66 207
LLPS-Orr-1703Oryza rufipogon59.641e-58 189
LLPS-Ors-0239Oryza sativa59.641e-58 189
LLPS-Orp-0139Oryza punctata59.043e-58 187
LLPS-Sei-1249Setaria italica57.933e-58 187
LLPS-Sem-0182Selaginella moellendorffii57.414e-62 196
LLPS-Coc-0069Corchorus capsularis57.062e-58 188
LLPS-Mua-0941Musa acuminata56.447e-59 189
LLPS-Amt-2283Amborella trichopoda53.913e-42 146
LLPS-Chr-1338Chlamydomonas reinhardtii50.01e-50 166
LLPS-Urm-0846Ursus maritimus47.311e-2089.4
LLPS-Osl-0098Ostreococcus lucimarinus45.754e-41 142
LLPS-Tar-3459Takifugu rubripes45.126e-35 126
LLPS-Gaa-0419Gasterosteus aculeatus44.517e-35 126
LLPS-Asm-2555Astyanax mexicanus44.241e-33 123
LLPS-Drm-1592Drosophila melanogaster44.19e-35 126
LLPS-Miv-0201Microbotryum violaceum43.981e-40 142
LLPS-Orn-0798Oreochromis niloticus43.642e-33 122
LLPS-Icp-2892Ictalurus punctatus43.643e-32 119
LLPS-Mel-0007Melampsora laricipopulina43.483e-27 105
LLPS-Scf-0583Scleropages formosus43.378e-34 124
LLPS-Orl-3194Oryzias latipes43.032e-34 125
LLPS-Mup-0416Mustela putorius furo42.736e-2497.4
LLPS-Pug-0077Puccinia graminis42.351e-37 135
LLPS-Nef-0396Neosartorya fischeri42.318e-27 105
LLPS-Asf-0627Aspergillus flavus42.315e-27 107
LLPS-Aso-0285Aspergillus oryzae42.313e-27 106
LLPS-Scm-2691Scophthalmus maximus42.076e-33 121
LLPS-Usm-0874Ustilago maydis42.015e-37 131
LLPS-Spr-1102Sporisorium reilianum42.011e-35 127
LLPS-Pof-3806Poecilia formosa41.822e-32 120
LLPS-Xim-0911Xiphophorus maculatus41.823e-32 119
LLPS-Asfu-1279Aspergillus fumigatus41.671e-26 105
LLPS-Chc-0689Chondrus crispus41.672e-26 104
LLPS-Asni-0185Aspergillus niger41.675e-26 103
LLPS-Asc-0198Aspergillus clavatus41.671e-25 102
LLPS-Scp-1313Schizosaccharomyces pombe41.363e-27 105
LLPS-Aim-2241Ailuropoda melanoleuca41.211e-26 105
LLPS-Ved-0437Verticillium dahliae40.883e-28 109
LLPS-Pyt-1304Pyrenophora teres40.887e-30 113
LLPS-Fec-1435Felis catus40.614e-27 107
LLPS-Mea-2835Mesocricetus auratus40.612e-29 112
LLPS-Anc-2242Anolis carolinensis40.493e-28 109
LLPS-Ten-3183Tetraodon nigroviridis40.437e-1057.4
LLPS-Asn-0341Aspergillus nidulans40.384e-25 100
LLPS-Fus-0638Fusarium solani40.372e-26 104
LLPS-Pytr-1002Pyrenophora triticirepentis40.256e-30 113
LLPS-Trv-0040Trichoderma virens40.137e-2395.1
LLPS-Phn-0451Phaeosphaeria nodorum40.02e-28 110
LLPS-Poa-1468Pongo abelii40.02e-27 109
LLPS-Mam-1803Macaca mulatta40.06e-28 109
LLPS-Cog-0389Colletotrichum gloeosporioides40.06e-2497.8
LLPS-Hos-0018Homo sapiens40.04e-28 109
LLPS-Pat-2096Pan troglodytes40.05e-28 109
LLPS-Pap-2436Pan paniscus40.05e-28 109
LLPS-Man-1632Macaca nemestrina40.06e-28 108
LLPS-Paa-1313Papio anubis40.02e-27 107
LLPS-Mal-1957Mandrillus leucophaeus40.06e-28 109
LLPS-Gog-0470Gorilla gorilla40.04e-28 109
LLPS-Caj-1136Callithrix jacchus40.05e-28 109
LLPS-Chs-0780Chlorocebus sabaeus40.05e-28 109
LLPS-Maf-0000Macaca fascicularis40.06e-28 109
LLPS-Cea-3655Cercocebus atys40.06e-28 109
LLPS-Xet-0902Xenopus tropicalis39.886e-30 113
LLPS-Mod-1303Monodelphis domestica39.881e-25 102
LLPS-Pes-0056Pelodiscus sinensis39.768e-27 105
LLPS-Scc-0449Schizosaccharomyces cryophilus39.512e-27 106
LLPS-Cap-2345Cavia porcellus39.392e-27 107
LLPS-Fud-2566Fukomys damarensis39.391e-27 107
LLPS-Aon-3366Aotus nancymaae39.392e-27 107
LLPS-Sah-2397Sarcophilus harrisii39.389e-25 100
LLPS-Lac-1452Latimeria chalumnae39.021e-28 110
LLPS-Ict-1422Ictidomys tridecemlineatus38.795e-27 106
LLPS-Otg-1475Otolemur garnettii38.794e-26 103
LLPS-Ran-0733Rattus norvegicus38.798e-25 100
LLPS-Myl-2703Myotis lucifugus38.793e-26 104
LLPS-Bot-4532Bos taurus38.791e-25 102
LLPS-Nol-0467Nomascus leucogenys38.753e-25 100
LLPS-Tum-0556Tuber melanosporum38.659e-26 102
LLPS-Cas-2436Carlito syrichta38.515e-2395.5
LLPS-Rhb-3107Rhinopithecus bieti38.414e-26 103
LLPS-Gas-0043Galdieria sulphuraria38.415e-30 114
LLPS-Scj-1434Schizosaccharomyces japonicus38.415e-25 100
LLPS-Fuo-0262Fusarium oxysporum38.369e-25 100
LLPS-Map-0484Magnaporthe poae38.362e-2499.4
LLPS-Fuv-0647Fusarium verticillioides38.369e-25 100
LLPS-Loa-1946Loxodonta africana38.121e-2499.0
LLPS-Crn-0880Cryptococcus neoformans38.11e-2192.4
LLPS-Dar-3219Danio rerio37.893e-25 101
LLPS-Ast-0532Aspergillus terreus37.893e-2498.6
LLPS-Scs-1086Sclerotinia sclerotiorum37.746e-2292.4
LLPS-Abg-1302Absidia glauca37.679e-1984.0
LLPS-Mum-1346Mus musculus37.656e-2498.6
LLPS-Ova-0672Ovis aries37.583e-26 104
LLPS-Tut-0491Tursiops truncatus37.584e-26 104
LLPS-Sus-1403Sus scrofa37.582e-26 103
LLPS-Lem-0893Leptosphaeria maculans37.54e-1779.0
LLPS-Dio-1494Dipodomys ordii37.57e-2394.7
LLPS-Coo-0443Colletotrichum orbiculare37.55e-2498.2
LLPS-Cogr-1489Colletotrichum graminicola37.413e-2190.5
LLPS-Dos-0792Dothistroma septosporum37.351e-2190.9
LLPS-Beb-0870Beauveria bassiana37.272e-2293.6
LLPS-Cym-0876Cyanidioschyzon merolae36.818e-26 103
LLPS-Yal-0782Yarrowia lipolytica36.533e-34 125
LLPS-Gag-0508Gaeumannomyces graminis36.482e-2294.0
LLPS-Ora-1340Ornithorhynchus anatinus36.427e-2189.4
LLPS-Trr-0508Trichoderma reesei36.366e-1676.3
LLPS-Eqc-2191Equus caballus36.22e-25 100
LLPS-Zyt-1020Zymoseptoria tritici35.855e-2190.1
LLPS-Kop-0576Komagataella pastoris35.626e-25 100
LLPS-Put-0107Puccinia triticina35.581e-1987.0
LLPS-Sac-1331Saccharomyces cerevisiae35.44e-2190.1
LLPS-Nec-1377Neurospora crassa35.197e-1984.3
LLPS-Blg-0761Blumeria graminis34.593e-2293.2
LLPS-Asg-1303Ashbya gossypii34.382e-2191.3
LLPS-Mao-0044Magnaporthe oryzae33.961e-1883.6