• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Php-1770
PHYPA_009708

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Proteasome subunit beta
Gene Name: PHYPA_009708, PHYPADRAFT_166946
Ensembl Gene: Pp3c7_520
Ensembl Protein: Pp3c7_520V3.1
Organism: Physcomitrella patens
Taxa ID: 3218
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, OthersPredicted from orthologs(View)

▼ FUNCTION

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSITSYNGSA  LIAMVGKNCF  AIASDRRLGV  NFQTIACDFQ  RIFKIHDKLY  IGLSGLATDV  60
61    QTMHQRLQFR  HKLYQLREER  NMRPETFASL  VSAILYEKRF  GPYFCEPIIA  GLNDDGTPFI  120
121   CTTDLIGAKQ  LAKDFVVSGT  ASESLYGACE  SMYKPDLGPD  ELFEVISQAL  LASVDRDCIS  180
181   GWGGIVHVVT  PDQVITKTLK  GRMD  204
Nucleotide CDS Sequence (FASTA)
1     ATGTCGATTA  CGAGCTACAA  TGGAAGTGCA  CTGATTGCCA  TGGTGGGCAA  GAATTGCTTC  60
61    GCCATCGCCA  GTGACCGCCG  TCTGGGTGTA  AATTTCCAGA  CGATTGCATG  TGATTTTCAG  120
121   CGCATATTTA  AGATACACGA  CAAGCTTTAC  ATTGGCCTCT  CTGGACTCGC  CACGGATGTG  180
181   CAAACCATGC  ACCAACGTTT  GCAATTTCGT  CATAAATTGT  ACCAACTGCG  AGAAGAGCGC  240
241   AACATGCGCC  CGGAAACTTT  TGCCAGTCTT  GTTTCGGCAA  TTCTTTACGA  GAAAAGGTTT  300
301   GGACCTTACT  TCTGCGAGCC  TATTATAGCC  GGACTTAACG  ATGACGGAAC  TCCTTTCATT  360
361   TGCACCACGG  ATTTGATCGG  TGCCAAGCAA  CTGGCGAAGG  ACTTCGTGGT  TTCTGGAACT  420
421   GCCTCAGAGT  CCCTGTATGG  TGCTTGCGAG  TCTATGTATA  AACCTGATTT  GGGTCCAGAT  480
481   GAGCTGTTCG  AGGTGATCTC  ACAAGCTCTA  CTGGCGTCTG  TGGACCGGGA  CTGCATTAGT  540
541   GGATGGGGAG  GGATTGTCCA  TGTTGTGACT  CCGGACCAAG  TTATTACCAA  GACCTTGAAG  600
601   GGCCGCATGG  ATTGA  615

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Hydrolase
Nucleus
Protease
Proteasome
Reference proteome
Threonine protease

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Nucleus
Cellular Component
Proteasome core complex
Cellular Component
Proteasome core complex, beta-subunit complex
Molecular Function
Endopeptidase activity
Molecular Function
Threonine-type endopeptidase activity
Biological Process
Proteasomal protein catabolic process
Biological Process
Proteasomal ubiquitin-independent protein catabolic process
Biological Process
Proteasome-mediated ubiquitin-dependent protein catabolic process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Vir-0531Vigna radiata82.543e-115 333
LLPS-Mua-1899Musa acuminata82.353e-124 357
LLPS-Orm-0676Oryza meridionalis82.083e-104 310
LLPS-Via-0920Vigna angularis81.484e-114 330
LLPS-Glm-2413Glycine max80.882e-122 352
LLPS-Dac-0054Daucus carota80.887e-124 356
LLPS-Orni-1898Oryza nivara80.423e-113 332
LLPS-Phv-0419Phaseolus vulgaris80.393e-122 352
LLPS-Sob-0624Sorghum bicolor80.391e-122 353
LLPS-Arl-0893Arabidopsis lyrata79.98e-121 348
LLPS-Tra-3088Triticum aestivum79.95e-122 351
LLPS-Brd-0072Brachypodium distachyon79.91e-122 352
LLPS-Nia-0877Nicotiana attenuata79.92e-122 352
LLPS-Sot-0559Solanum tuberosum79.413e-122 352
LLPS-Met-0215Medicago truncatula79.418e-120 345
LLPS-Sol-1937Solanum lycopersicum79.314e-118 353
LLPS-Hov-0174Hordeum vulgare78.927e-121 348
LLPS-Brn-2027Brassica napus78.922e-120 347
LLPS-Tru-0422Triticum urartu78.927e-120 345
LLPS-Bro-0370Brassica oleracea78.925e-120 346
LLPS-Brr-1411Brassica rapa78.925e-120 346
LLPS-Gor-2235Gossypium raimondii78.925e-120 346
LLPS-Art-0248Arabidopsis thaliana78.923e-120 347
LLPS-Amt-0195Amborella trichopoda78.926e-120 346
LLPS-Orbr-0495Oryza brachyantha78.926e-122 351
LLPS-Orgl-1653Oryza glumaepatula78.431e-118 346
LLPS-Cus-1093Cucumis sativus78.436e-121 348
LLPS-Ori-0393Oryza indica78.434e-120 346
LLPS-Thc-1047Theobroma cacao78.437e-120 345
LLPS-Hea-0975Helianthus annuus78.431e-120 348
LLPS-Orr-0200Oryza rufipogon78.434e-120 346
LLPS-Org-1606Oryza glaberrima78.434e-120 346
LLPS-Orp-1518Oryza punctata78.432e-119 347
LLPS-Ors-1563Oryza sativa78.434e-120 346
LLPS-Pot-1293Populus trichocarpa77.945e-123 353
LLPS-Sei-0750Setaria italica77.451e-120 350
LLPS-Orb-0298Oryza barthii77.458e-119 343
LLPS-Sem-1855Selaginella moellendorffii77.455e-120 346
LLPS-Prp-1996Prunus persica77.455e-119 343
LLPS-Coc-0137Corchorus capsularis76.967e-118 340
LLPS-Viv-1589Vitis vinifera76.966e-120 346
LLPS-Lep-1281Leersia perrieri76.732e-117 340
LLPS-Zem-0339Zea mays75.944e-116 337
LLPS-Mae-2260Manihot esculenta68.752e-98 291
LLPS-Ora-1390Ornithorhynchus anatinus64.063e-2192.0
LLPS-Asm-0249Astyanax mexicanus60.982e-91 273
LLPS-Orn-2468Oreochromis niloticus60.493e-90 270
LLPS-Lem-0429Leptosphaeria maculans60.153e-54 176
LLPS-Icp-1858Ictalurus punctatus60.02e-90 271
LLPS-Gaga-1168Gallus gallus60.05e-90 270
LLPS-Scm-0814Scophthalmus maximus60.03e-90 270
LLPS-Scf-1960Scleropages formosus59.519e-89 266
LLPS-Gaa-2040Gasterosteus aculeatus59.516e-90 270
LLPS-Tar-3525Takifugu rubripes59.511e-88 266
LLPS-Cii-1525Ciona intestinalis59.519e-88 264
LLPS-Meg-0038Meleagris gallopavo59.512e-89 268
LLPS-Leo-1099Lepisosteus oculatus59.475e-81 248
LLPS-Chr-0455Chlamydomonas reinhardtii59.411e-80 245
LLPS-Xet-1165Xenopus tropicalis59.262e-80 244
LLPS-Xim-2529Xiphophorus maculatus59.024e-89 267
LLPS-Sah-0503Sarcophilus harrisii59.023e-88 265
LLPS-Mum-3447Mus musculus59.021e-87 263
LLPS-Mod-0069Monodelphis domestica59.028e-88 264
LLPS-Fec-0355Felis catus59.022e-87 263
LLPS-Dar-2051Danio rerio59.022e-88 266
LLPS-Loa-0407Loxodonta africana58.823e-87 263
LLPS-Pes-2522Pelodiscus sinensis58.822e-87 263
LLPS-Abg-1895Absidia glauca58.797e-90 269
LLPS-Dio-2791Dipodomys ordii58.543e-87 263
LLPS-Sus-1955Sus scrofa58.542e-87 263
LLPS-Caf-0118Canis familiaris58.543e-87 263
LLPS-Hos-0240Homo sapiens58.542e-87 263
LLPS-Pat-1793Pan troglodytes58.542e-87 263
LLPS-Ten-0807Tetraodon nigroviridis58.332e-86 261
LLPS-Cas-0531Carlito syrichta58.331e-86 261
LLPS-Osl-0495Ostreococcus lucimarinus58.255e-84 254
LLPS-Pof-1161Poecilia formosa58.255e-87 262
LLPS-Fia-1237Ficedula albicollis58.256e-82 249
LLPS-Urm-2361Ursus maritimus58.231e-62 202
LLPS-Pap-0077Pan paniscus58.211e-85 258
LLPS-Orl-1340Oryzias latipes58.162e-55 182
LLPS-Anp-1161Anas platyrhynchos58.167e-57 183
LLPS-Bot-1103Bos taurus58.056e-87 262
LLPS-Tut-0946Tursiops truncatus58.053e-87 263
LLPS-Ova-2073Ovis aries58.056e-87 262
LLPS-Myl-0606Myotis lucifugus58.051e-86 261
LLPS-Paa-0689Papio anubis58.056e-87 262
LLPS-Mal-1579Mandrillus leucophaeus58.056e-87 262
LLPS-Ere-0721Erinaceus europaeus58.052e-86 261
LLPS-Ran-0700Rattus norvegicus58.054e-87 262
LLPS-Cea-2194Cercocebus atys58.056e-87 262
LLPS-Aon-0556Aotus nancymaae58.056e-87 262
LLPS-Chs-3542Chlorocebus sabaeus58.056e-87 262
LLPS-Maf-2114Macaca fascicularis58.056e-87 262
LLPS-Gog-2135Gorilla gorilla58.053e-87 263
LLPS-Mam-1582Macaca mulatta58.056e-87 262
LLPS-Anc-1171Anolis carolinensis58.055e-87 262
LLPS-Nol-0014Nomascus leucogenys58.056e-87 262
LLPS-Ict-1841Ictidomys tridecemlineatus58.056e-87 262
LLPS-Man-1792Macaca nemestrina58.056e-87 262
LLPS-Rhb-0429Rhinopithecus bieti58.056e-87 262
LLPS-Scp-0534Schizosaccharomyces pombe57.845e-87 262
LLPS-Chc-0952Chondrus crispus57.842e-89 268
LLPS-Aim-1306Ailuropoda melanoleuca57.845e-86 259
LLPS-Caj-0267Callithrix jacchus57.843e-86 260
LLPS-Poa-1442Pongo abelii57.842e-85 258
LLPS-Orc-1479Oryctolagus cuniculus57.843e-86 260
LLPS-Eqc-1860Equus caballus57.711e-85 259
LLPS-Fud-2107Fukomys damarensis57.566e-86 259
LLPS-Cap-0107Cavia porcellus57.353e-83 253
LLPS-Gas-0936Galdieria sulphuraria57.142e-85 258
LLPS-Scj-0061Schizosaccharomyces japonicus56.861e-83 254
LLPS-Mea-0006Mesocricetus auratus56.595e-79 241
LLPS-Coo-1214Colletotrichum orbiculare56.251e-73 228
LLPS-Scc-0532Schizosaccharomyces cryophilus55.881e-82 251
LLPS-Cog-0215Colletotrichum gloeosporioides55.735e-73 226
LLPS-Tum-0850Tuber melanosporum55.725e-73 238
LLPS-Cogr-0595Colletotrichum graminicola55.721e-76 236
LLPS-Mao-0020Magnaporthe oryzae55.225e-78 239
LLPS-Pytr-0415Pyrenophora triticirepentis55.222e-76 235
LLPS-Trv-0793Trichoderma virens55.223e-74 229
LLPS-Pyt-0048Pyrenophora teres55.217e-73 226
LLPS-Trr-0787Trichoderma reesei55.217e-71 221
LLPS-Mel-0649Melampsora laricipopulina55.052e-81 248
LLPS-Asfu-0362Aspergillus fumigatus54.692e-73 227
LLPS-Yal-0850Yarrowia lipolytica54.598e-71 221
LLPS-Phn-1005Phaeosphaeria nodorum54.591e-70 220
LLPS-Spr-1195Sporisorium reilianum54.414e-87 262
LLPS-Usm-0330Ustilago maydis54.417e-88 264
LLPS-Asni-0238Aspergillus niger54.277e-76 234
LLPS-Nec-1170Neurospora crassa54.232e-75 233
LLPS-Gag-0274Gaeumannomyces graminis54.231e-74 231
LLPS-Map-0152Magnaporthe poae54.234e-74 229
LLPS-Fuv-0590Fusarium verticillioides54.172e-70 219
LLPS-Fuo-1036Fusarium oxysporum54.172e-70 219
LLPS-Asc-0166Aspergillus clavatus53.773e-75 232
LLPS-Fus-0411Fusarium solani53.731e-73 228
LLPS-Ast-0956Aspergillus terreus53.653e-72 224
LLPS-Nef-0181Neosartorya fischeri53.653e-72 224
LLPS-Pug-0515Puccinia graminis53.433e-80 245
LLPS-Asf-0243Aspergillus flavus53.271e-75 233
LLPS-Blg-1401Blumeria graminis53.232e-73 228
LLPS-Dos-0606Dothistroma septosporum53.233e-76 234
LLPS-Beb-0802Beauveria bassiana53.232e-72 225
LLPS-Kop-0498Komagataella pastoris52.746e-73 226
LLPS-Asn-1216Aspergillus nidulans52.62e-70 219
LLPS-Miv-0380Microbotryum violaceum52.458e-74 228
LLPS-Zyt-0376Zymoseptoria tritici52.267e-75 231
LLPS-Aso-1032Aspergillus oryzae52.222e-76 235
LLPS-Crn-0857Cryptococcus neoformans51.92e-77 238
LLPS-Drm-1611Drosophila melanogaster51.223e-78 239
LLPS-Ved-0256Verticillium dahliae50.758e-65 206
LLPS-Sac-1024Saccharomyces cerevisiae50.52e-71 222
LLPS-Cym-0167Cyanidioschyzon merolae49.752e-73 227
LLPS-Mup-0719Mustela putorius furo49.024e-63 200
LLPS-Asg-0301Ashbya gossypii46.532e-65 207
LLPS-Cae-0233Caenorhabditis elegans44.615e-69 216
LLPS-Otg-0472Otolemur garnettii42.921e-45 156
LLPS-Put-0476Puccinia triticina42.551e-59 192
LLPS-Lac-0567Latimeria chalumnae26.117e-1985.5