LLPS-Pes-a888
GNG4
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Guanine nucleotide-binding protein subunit gamma |
| Gene Name: | GNG4 |
| Ensembl Gene: | ENSPSIG00000013489.1 |
| Ensembl Protein: | ENSPSIP00000015074.1 |
| Organism: | Pelodiscus sinensis |
| Taxa ID: | 13735 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPSIT00000015145.1 | ENSPSIP00000015074.1 |
| UniProt | K7G463, K7G463_PELSI | |
| GeneBank | AGCU01078992, AGCU01078989, AGCU01078991, AGCU01078990, AGCU01078988 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MKEVISNNTT NISQARKAVE QLKMEAYMDR IKVSKAAADL LAYCEAHIGE DPLIIPVPAS 60 61 ENPFREKKLF CTIL 74 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAAGGAAG TAATTTCTAA TAACACAACC AATATATCTC AAGCAAGGAA AGCTGTGGAG 60 61 CAGTTAAAAA TGGAAGCATA CATGGACAGG ATAAAGGTAT CCAAGGCTGC AGCTGATTTA 120 121 TTAGCATACT GTGAGGCTCA TATCGGAGAA GATCCCCTTA TTATACCAGT GCCTGCATCT 180 181 GAAAATCCCT TCAGGGAGAA GAAACTCTTT TGTACTATTC TCTGA 225 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Heterotrimeric G-protein complex | |
Molecular Function | GTPase activity | |
Biological Process | G protein-coupled receptor signaling pathway | |
Biological Process | Negative regulation of cell growth |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Mum-a1213 | Mus musculus | 4e-22 | 88.6 | undefined |
| LLPS-Hos-a1066 | Homo sapiens | 3e-33 | 119 | undefined |