LLPS-Pes-3124
GTF2E2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Transcription initiation factor IIE subunit beta |
| Gene Name: | GTF2E2 |
| Ensembl Gene: | ENSPSIG00000006031.1 |
| Ensembl Protein: | ENSPSIP00000006551.1 |
| Organism: | Pelodiscus sinensis |
| Taxa ID: | 13735 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPSIT00000006588.1 | ENSPSIP00000006551.1 |
| UniProt | K7FEU1, K7FEU1_PELSI | |
| GeneBank | AGCU01101968, AGCU01101969, AGCU01101967, AGCU01101970 | |
| RefSeq | XM_006125382.2 | XP_006125444.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MDPSLLRERE LFKKRALSTP AVEKRTAASD SASSKKKKAK VEQGGSSSSK QNTDHNNGSF 60 61 NLKALSGGSG YKFGVLAKIV NYMKTRHQRG DTHPLALEEI LDETQHLDIG LRQKQWLMSE 120 121 ALVSNPKIEV IDGKYAFKPK YNLKDKKALL RLLDKHDQRG LGGILLEDIE EGLPNAQKAI 180 181 KALGDQIIFI TRPDKKKILF YNDKSCQFTV DEEFQKLWRS IPVDSMDEEK IEEYLKRQGI 240 241 SSMQEAGPKK IAPIQRRKKP ASQKKRRFKT HNDHLAGVLK DYSDVAPGKQ 290 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGATCCAA GCTTGCTAAG AGAACGAGAG CTATTCAAAA AACGAGCACT CTCCACTCCT 60 61 GCTGTAGAAA AGCGTACAGC AGCTTCTGAT TCAGCATCTT CCAAAAAGAA AAAAGCAAAG 120 121 GTAGAGCAGG GTGGATCATC GAGCTCAAAA CAAAACACAG ACCACAACAA TGGGTCGTTT 180 181 AATTTGAAAG CCCTCTCAGG AGGCTCTGGC TACAAGTTTG GAGTCCTTGC TAAGATAGTG 240 241 AATTATATGA AGACACGGCA CCAGCGTGGT GATACACATC CATTAGCTCT AGAAGAAATT 300 301 TTGGATGAAA CGCAACACTT AGATATTGGA CTCAGACAGA AACAATGGTT AATGAGTGAG 360 361 GCTCTAGTCA GCAATCCTAA AATAGAAGTT ATAGATGGGA AATATGCTTT CAAACCAAAG 420 421 TACAATTTGA AAGATAAAAA GGCTCTGCTC AGGCTCTTGG ACAAGCATGA CCAACGGGGA 480 481 CTCGGAGGAA TCCTTCTGGA AGATATTGAG GAAGGACTGC CCAATGCACA GAAAGCCATA 540 541 AAGGCTTTAG GGGACCAGAT TATCTTTATT ACTCGTCCTG ATAAGAAGAA AATCCTTTTC 600 601 TACAATGATA AGAGCTGTCA ATTTACAGTA GATGAAGAAT TTCAGAAGCT GTGGCGGAGC 660 661 ATTCCTGTGG ATTCTATGGA TGAGGAAAAA ATAGAGGAGT ATCTGAAACG ACAGGGTATT 720 721 TCTTCCATGC AAGAAGCCGG ACCAAAGAAA ATAGCTCCTA TTCAGAGGAG GAAGAAACCT 780 781 GCTTCTCAGA AGAAACGGCG GTTTAAGACT CACAATGACC ATTTGGCTGG AGTACTGAAG 840 841 GATTACTCTG ATGTTGCTCC TGGCAAGCAG TGA 873 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Nuclear speck | |
Cellular Component | Transcription factor TFIID complex | |
Cellular Component | Transcription factor TFIIE complex | |
Molecular Function | DNA binding | |
Molecular Function | RNA polymerase II general transcription initiation factor activity | |
Biological Process | Transcription initiation from RNA polymerase II promoter |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ora-2212 | Ornithorhynchus anatinus | 94.81 | 4e-150 | 427 |
| LLPS-Sah-1037 | Sarcophilus harrisii | 94.15 | 7e-129 | 373 |
| LLPS-Tag-2117 | Taeniopygia guttata | 93.47 | 8e-178 | 500 |
| LLPS-Anc-0860 | Anolis carolinensis | 91.72 | 2e-175 | 494 |
| LLPS-Mod-1442 | Monodelphis domestica | 90.72 | 6e-173 | 488 |
| LLPS-Orc-3015 | Oryctolagus cuniculus | 90.3 | 2e-149 | 426 |
| LLPS-Poa-3810 | Pongo abelii | 89.27 | 1e-145 | 416 |
| LLPS-Caf-0799 | Canis familiaris | 89.0 | 5e-171 | 483 |
| LLPS-Aim-0054 | Ailuropoda melanoleuca | 88.97 | 4e-170 | 480 |
| LLPS-Bot-2566 | Bos taurus | 88.93 | 1e-173 | 489 |
| LLPS-Dio-3699 | Dipodomys ordii | 88.71 | 4e-57 | 186 |
| LLPS-Urm-3797 | Ursus maritimus | 88.66 | 8e-170 | 480 |
| LLPS-Fec-1245 | Felis catus | 88.32 | 4e-169 | 478 |
| LLPS-Ova-0798 | Ovis aries | 88.32 | 6e-171 | 482 |
| LLPS-Mea-1518 | Mesocricetus auratus | 88.32 | 9e-170 | 479 |
| LLPS-Eqc-3475 | Equus caballus | 88.28 | 2e-169 | 480 |
| LLPS-Sus-2325 | Sus scrofa | 87.97 | 8e-168 | 474 |
| LLPS-Rhb-2486 | Rhinopithecus bieti | 87.89 | 9e-170 | 479 |
| LLPS-Mam-3371 | Macaca mulatta | 87.8 | 5e-124 | 360 |
| LLPS-Anp-2222 | Anas platyrhynchos | 87.67 | 2e-170 | 481 |
| LLPS-Ict-0887 | Ictidomys tridecemlineatus | 87.29 | 1e-168 | 477 |
| LLPS-Mup-1048 | Mustela putorius furo | 87.11 | 3e-142 | 409 |
| LLPS-Otg-0222 | Otolemur garnettii | 86.99 | 1e-168 | 476 |
| LLPS-Cap-2508 | Cavia porcellus | 86.69 | 4e-169 | 478 |
| LLPS-Cas-2842 | Carlito syrichta | 86.6 | 2e-169 | 479 |
| LLPS-Ran-0670 | Rattus norvegicus | 86.6 | 6e-169 | 477 |
| LLPS-Mal-1021 | Mandrillus leucophaeus | 86.6 | 9e-168 | 474 |
| LLPS-Paa-3215 | Papio anubis | 86.6 | 9e-168 | 474 |
| LLPS-Cea-2116 | Cercocebus atys | 86.6 | 9e-168 | 474 |
| LLPS-Nol-2419 | Nomascus leucogenys | 86.25 | 5e-167 | 472 |
| LLPS-Hos-1049 | Homo sapiens | 86.25 | 1e-166 | 471 |
| LLPS-Pat-2622 | Pan troglodytes | 86.25 | 1e-166 | 471 |
| LLPS-Pap-3128 | Pan paniscus | 86.25 | 1e-166 | 471 |
| LLPS-Man-0729 | Macaca nemestrina | 86.25 | 3e-167 | 473 |
| LLPS-Maf-1761 | Macaca fascicularis | 86.25 | 3e-167 | 473 |
| LLPS-Gog-1239 | Gorilla gorilla | 86.25 | 1e-166 | 471 |
| LLPS-Mum-1090 | Mus musculus | 85.96 | 9e-169 | 477 |
| LLPS-Loa-1846 | Loxodonta africana | 85.91 | 9e-164 | 464 |
| LLPS-Aon-0597 | Aotus nancymaae | 85.91 | 3e-167 | 473 |
| LLPS-Caj-2610 | Callithrix jacchus | 85.52 | 3e-166 | 471 |
| LLPS-Lac-0691 | Latimeria chalumnae | 85.32 | 6e-160 | 454 |
| LLPS-Tut-1494 | Tursiops truncatus | 85.11 | 5e-138 | 396 |
| LLPS-Fud-3875 | Fukomys damarensis | 84.98 | 2e-169 | 478 |
| LLPS-Meg-0381 | Meleagris gallopavo | 84.88 | 1e-159 | 454 |
| LLPS-Leo-2498 | Lepisosteus oculatus | 84.48 | 3e-156 | 445 |
| LLPS-Gaga-1233 | Gallus gallus | 84.19 | 2e-153 | 438 |
| LLPS-Scf-0661 | Scleropages formosus | 82.76 | 7e-153 | 436 |
| LLPS-Icp-1163 | Ictalurus punctatus | 78.97 | 5e-146 | 419 |
| LLPS-Orl-1656 | Oryzias latipes | 77.78 | 7e-140 | 405 |
| LLPS-Asm-2675 | Astyanax mexicanus | 77.66 | 5e-145 | 416 |
| LLPS-Myl-0516 | Myotis lucifugus | 77.13 | 1e-139 | 403 |
| LLPS-Xim-1488 | Xiphophorus maculatus | 76.55 | 4e-135 | 391 |
| LLPS-Pof-0462 | Poecilia formosa | 76.21 | 2e-134 | 389 |
| LLPS-Tar-1669 | Takifugu rubripes | 76.21 | 8e-134 | 388 |
| LLPS-Xet-0799 | Xenopus tropicalis | 75.09 | 7e-141 | 406 |
| LLPS-Orn-0029 | Oreochromis niloticus | 74.91 | 3e-134 | 389 |
| LLPS-Scm-0499 | Scophthalmus maximus | 73.45 | 1e-130 | 379 |
| LLPS-Ten-0478 | Tetraodon nigroviridis | 72.88 | 6e-129 | 375 |
| LLPS-Gaa-2767 | Gasterosteus aculeatus | 70.93 | 3e-129 | 376 |
| LLPS-Dar-3760 | Danio rerio | 70.87 | 2e-136 | 396 |
| LLPS-Cii-1123 | Ciona intestinalis | 54.3 | 6e-84 | 261 |
| LLPS-Drm-1531 | Drosophila melanogaster | 49.83 | 5e-79 | 248 |
| LLPS-Cae-1237 | Caenorhabditis elegans | 38.85 | 2e-48 | 169 |
| LLPS-Blg-1212 | Blumeria graminis | 32.09 | 2e-07 | 55.5 |
| LLPS-Scc-0771 | Schizosaccharomyces cryophilus | 31.25 | 4e-06 | 51.6 |
| LLPS-Fus-1305 | Fusarium solani | 31.06 | 2e-06 | 52.4 |
| LLPS-Asc-1029 | Aspergillus clavatus | 31.01 | 2e-11 | 67.4 |
| LLPS-Asfu-1215 | Aspergillus fumigatus | 30.66 | 2e-14 | 75.9 |
| LLPS-Nef-0234 | Neosartorya fischeri | 30.19 | 6e-14 | 73.9 |
| LLPS-Scp-0240 | Schizosaccharomyces pombe | 29.53 | 1e-09 | 62.0 |
| LLPS-Ast-0526 | Aspergillus terreus | 28.89 | 2e-12 | 70.1 |
| LLPS-Asni-0565 | Aspergillus niger | 28.89 | 3e-11 | 66.6 |
| LLPS-Cym-0021 | Cyanidioschyzon merolae | 28.43 | 1e-06 | 52.8 |
| LLPS-Aso-1000 | Aspergillus oryzae | 28.3 | 5e-12 | 68.9 |
| LLPS-Asf-1191 | Aspergillus flavus | 28.3 | 5e-12 | 68.9 |
| LLPS-Asn-0580 | Aspergillus nidulans | 27.36 | 2e-09 | 61.6 |
| LLPS-Beb-0352 | Beauveria bassiana | 27.27 | 1e-06 | 53.1 |