• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Pat-a871
ATP5MG

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: ATP synthase subunit
Gene Name: ATP5MG, ATP5L, CK820_G0015730
Ensembl Gene: ENSPTRG00000004342.4
Ensembl Protein: ENSPTRP00000007446.3
Organism: Pan troglodytes
Taxa ID: 9598
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION


Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.

▼ SEQUENCE


Protein Sequence (FASTA)
1     MAQFVRNLVE  KTPALVNAAV  TYSKPRLATF  WYYAKVELVP  PTPAEIPRAI  QSLKKIVNSA  60
61    QTGSFKQLTV  KEAVLNGLVA  TEVLMWFYVG  EIIGKRGIIG  YDV  103
Nucleotide CDS Sequence (FASTA)
1     ATGGCCCAAT  TTGTCCGTAA  CCTTGTGGAG  AAGACCCCGG  CGCTGGTGAA  CGCTGCTGTG  60
61    ACTTACTCGA  AGCCTCGATT  GGCCACATTT  TGGTACTACG  CCAAGGTTGA  GCTGGTTCCT  120
121   CCCACCCCTG  CTGAGATCCC  TAGAGCTATT  CAGAGCCTGA  AAAAAATAGT  CAATAGTGCT  180
181   CAGACTGGTA  GCTTCAAACA  GCTCACAGTT  AAGGAAGCTG  TGCTGAATGG  TTTGGTGGCC  240
241   ACTGAGGTGT  TGATGTGGTT  TTATGTCGGA  GAGATTATAG  GCAAGCGGGG  CATCATTGGC  300
301   TATGATGTTT  GA  312

▼ KEYWORD


ID
Family
ATP synthesis
CF(0)
Complete proteome
Hydrogen ion transport
Ion transport
Membrane
Mitochondrion
Reference proteome
Transport

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
Molecular Function
ATPase activity
Molecular Function
Proton transmembrane transporter activity
Biological Process
ATP hydrolysis coupled cation transmembrane transport
Biological Process
ATP synthesis coupled proton transport

▼ KEGG



▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mum-a869Mus musculus8e-58182undefined
LLPS-Hos-a883Homo sapiens3e-68208undefined