LLPS-Pat-3204
SAMHD1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 |
| Gene Name: | SAMHD1, CK820_G0020182 |
| Ensembl Gene: | ENSPTRG00000013468.5 |
| Ensembl Protein: | ENSPTRP00000023119.5 |
| Organism: | Pan troglodytes |
| Taxa ID: | 9598 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPTRT00000025051.5 | ENSPTRP00000023119.5 |
| UniProt | H6WE97, H6WE97_PANTR, A0A2J8MKX9, H2QKA9 | |
| GeneBank | AACZ04052781, JQ085410, JQ231123, NBAG03000253, JN936887, JQ085411, GABF01006234 | , AFU88758.1, AFB71157.1, JAA15911.1, PNI60166.1, AFJ79637.1, AFJ79636.1 |
| RefSeq | NM_001280510.1 | NP_001267439.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MQRADSEQPS KRPRCDDSPR TPSNTPSAEA DWSPGLELHP DYKTWGPEQV CSFLRRGGFE 60 61 ELVLLKNIRE NEITGALLPC LDESRFENLG VSSLGERKKL LSYIQRLVQI HVDTMKVIND 120 121 PIHGHIELHP LLVRIIDTPQ FQRLRYIKQL GGGYYVFPGA SHNRFEHSLG VGYLAGCLVR 180 181 ALGEKQPELQ ISERDILCVQ IAGLCHDLGH GPFSHMFDGR FIPLARPEVK WTHEQGSVMM 240 241 FEHLINSNGI KPVMEQYGLI PEEDICFIKE QIVGPLESPV EDSLWPYKGR PENKSFLYEI 300 301 VSNKRNGIDV DKWDYFARDC HHLGIQNNFD YKRFIKFARV CEVDNELRIC ARDKEVGNLY 360 361 DMFHTRNSLH RRAYQHKVGN IIDTMITDAF LKADDYIEIT GAGGKKYRIS TAIDDMEAYT 420 421 KLTDNIFLEI LYSTDPKLKD AREILKQIEY RNLFKYVGET QPTGQIKIKR EDYESLPKEV 480 481 ASAKPKVLLD VKLKAEDFIV DVINMDYGMQ EKNPIDHVSF YCKTAPNRAI RITKNQVSQL 540 541 LPEKFAEQLI RVYCKKVDRK SLYAARQHFV QWCADRNFTK PQDGDVIAPL ITPQKKEWND 600 601 STSVQNPTRL REASKSRVQL FKDDPM 626 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCAGCGAG CCGATTCCGA GCAGCCCTCC AAGCGTCCCC GTTGCGATGA CAGCCCGAGA 60 61 ACCCCCTCAA ACACCCCTTC CGCAGAGGCA GACTGGTCCC CGGGCCTGGA ACTCCATCCC 120 121 GACTACAAGA CATGGGGTCC GGAGCAGGTG TGCTCCTTCC TCAGGCGCGG TGGCTTTGAA 180 181 GAGCTGGTGC TGCTGAAGAA CATCCGAGAA AATGAAATCA CAGGCGCATT ACTGCCCTGT 240 241 CTTGATGAGT CTCGTTTTGA AAATCTTGGA GTAAGTTCCT TGGGGGAGAG GAAGAAGCTG 300 301 CTTAGTTATA TCCAGCGATT GGTTCAAATC CACGTTGATA CAATGAAGGT AATTAATGAT 360 361 CCTATCCATG GCCACATTGA GCTCCACCCT CTCCTTGTCC GAATCATTGA TACACCTCAA 420 421 TTTCAACGTC TTCGATACAT CAAACAGCTG GGAGGTGGTT ACTATGTTTT TCCAGGAGCT 480 481 TCACACAATC GATTTGAGCA TAGTCTAGGG GTGGGGTATC TAGCAGGATG TCTAGTTCGC 540 541 GCACTGGGTG AAAAACAACC AGAGCTGCAG ATAAGTGAAC GAGATATTCT CTGTGTTCAG 600 601 ATTGCTGGAC TTTGTCATGA TCTCGGTCAT GGGCCATTTT CTCACATGTT TGATGGACGA 660 661 TTTATTCCAC TTGCTCGCCC GGAGGTGAAA TGGACGCATG AACAAGGCTC AGTTATGATG 720 721 TTTGAGCACC TTATTAATTC TAATGGAATC AAGCCTGTCA TGGAACAATA TGGTCTCATC 780 781 CCTGAAGAAG ATATTTGCTT TATAAAGGAA CAAATTGTAG GACCACTTGA ATCACCTGTC 840 841 GAAGATTCAT TGTGGCCATA TAAAGGGCGT CCTGAAAACA AAAGCTTCCT TTATGAGATA 900 901 GTGTCTAATA AAAGAAATGG CATTGATGTG GACAAATGGG ATTATTTTGC CAGGGACTGC 960 961 CATCATCTTG GAATCCAAAA TAATTTTGAT TACAAGCGCT TTATTAAGTT TGCCCGTGTC 1020 1021 TGTGAAGTAG ACAATGAGTT GCGTATTTGT GCTAGAGATA AGGAAGTTGG AAATCTGTAT 1080 1081 GACATGTTCC ACACTCGCAA CTCTTTACAC CGTAGAGCTT ATCAACACAA AGTTGGCAAC 1140 1141 ATTATTGATA CAATGATTAC AGATGCTTTC CTCAAAGCAG ATGACTACAT AGAGATTACA 1200 1201 GGTGCTGGAG GAAAAAAGTA TCGCATTTCT ACAGCAATTG ACGACATGGA AGCCTATACT 1260 1261 AAGCTGACAG ATAACATTTT TCTGGAGATT TTATACTCTA CTGATCCCAA ATTGAAAGAC 1320 1321 GCACGAGAGA TTTTGAAACA AATTGAATAC CGTAATCTAT TCAAGTATGT GGGTGAGACG 1380 1381 CAGCCAACAG GACAAATAAA GATTAAAAGG GAGGACTATG AATCTCTTCC AAAAGAGGTT 1440 1441 GCCAGTGCTA AACCCAAAGT ATTGCTAGAC GTGAAACTGA AGGCTGAAGA TTTTATAGTG 1500 1501 GATGTTATCA ACATGGATTA TGGAATGCAA GAAAAGAATC CAATTGATCA TGTTAGCTTC 1560 1561 TATTGTAAGA CTGCCCCCAA CAGAGCAATC AGGATTACTA AAAACCAGGT TTCACAACTT 1620 1621 CTGCCAGAGA AATTTGCAGA GCAGCTGATT CGAGTATATT GTAAGAAGGT GGACAGAAAG 1680 1681 AGTTTGTATG CCGCAAGACA ACATTTTGTT CAGTGGTGTG CAGACAGAAA TTTCACCAAG 1740 1741 CCGCAGGATG GCGATGTTAT AGCCCCACTC ATAACACCTC AAAAAAAGGA ATGGAACGAC 1800 1801 AGTACTTCAG TCCAAAATCC AACTCGCCTC CGAGAAGCAT CCAAAAGCAG AGTCCAGCTT 1860 1861 TTTAAAGATG ACCCAATGTG A 1881 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Pap-1325 | Pan paniscus | 100.0 | 0.0 | 1304 |
| LLPS-Hos-2108 | Homo sapiens | 99.36 | 0.0 | 1296 |
| LLPS-Gog-3673 | Gorilla gorilla | 99.2 | 0.0 | 1296 |
| LLPS-Poa-1635 | Pongo abelii | 96.01 | 0.0 | 1253 |
| LLPS-Nol-0420 | Nomascus leucogenys | 95.69 | 0.0 | 1252 |
| LLPS-Rhb-3157 | Rhinopithecus bieti | 94.74 | 0.0 | 1233 |
| LLPS-Maf-4782 | Macaca fascicularis | 94.4 | 0.0 | 1228 |
| LLPS-Paa-3529 | Papio anubis | 94.24 | 0.0 | 1226 |
| LLPS-Mal-2373 | Mandrillus leucophaeus | 94.08 | 0.0 | 1221 |
| LLPS-Mam-1777 | Macaca mulatta | 94.08 | 0.0 | 1223 |
| LLPS-Cea-4610 | Cercocebus atys | 93.92 | 0.0 | 1220 |
| LLPS-Chs-4190 | Chlorocebus sabaeus | 93.44 | 0.0 | 1214 |
| LLPS-Caj-1945 | Callithrix jacchus | 88.2 | 0.0 | 1156 |
| LLPS-Man-2514 | Macaca nemestrina | 87.68 | 0.0 | 1113 |
| LLPS-Cas-3365 | Carlito syrichta | 85.04 | 0.0 | 919 |
| LLPS-Ora-1270 | Ornithorhynchus anatinus | 83.57 | 5e-73 | 238 |
| LLPS-Eqc-3560 | Equus caballus | 82.72 | 0.0 | 1083 |
| LLPS-Sus-2812 | Sus scrofa | 80.86 | 0.0 | 1036 |
| LLPS-Fud-4420 | Fukomys damarensis | 80.36 | 0.0 | 1028 |
| LLPS-Tut-1780 | Tursiops truncatus | 79.04 | 0.0 | 1021 |
| LLPS-Loa-0832 | Loxodonta africana | 78.85 | 0.0 | 1023 |
| LLPS-Aim-1106 | Ailuropoda melanoleuca | 78.72 | 0.0 | 1045 |
| LLPS-Urm-2509 | Ursus maritimus | 78.63 | 0.0 | 1042 |
| LLPS-Mup-0930 | Mustela putorius furo | 77.88 | 0.0 | 1021 |
| LLPS-Caf-3983 | Canis familiaris | 77.67 | 0.0 | 1038 |
| LLPS-Fec-4307 | Felis catus | 77.35 | 0.0 | 1028 |
| LLPS-Ict-0427 | Ictidomys tridecemlineatus | 77.11 | 0.0 | 996 |
| LLPS-Bot-4689 | Bos taurus | 77.05 | 0.0 | 919 |
| LLPS-Ova-3553 | Ovis aries | 76.31 | 0.0 | 984 |
| LLPS-Mea-0905 | Mesocricetus auratus | 76.19 | 9e-73 | 238 |
| LLPS-Otg-4319 | Otolemur garnettii | 76.14 | 0.0 | 936 |
| LLPS-Orc-0772 | Oryctolagus cuniculus | 73.68 | 0.0 | 952 |
| LLPS-Ran-1215 | Rattus norvegicus | 73.16 | 0.0 | 943 |
| LLPS-Mum-3337 | Mus musculus | 72.78 | 0.0 | 922 |
| LLPS-Pes-3542 | Pelodiscus sinensis | 71.94 | 0.0 | 837 |
| LLPS-Anp-2805 | Anas platyrhynchos | 70.85 | 0.0 | 669 |
| LLPS-Mod-2138 | Monodelphis domestica | 69.87 | 0.0 | 897 |
| LLPS-Cap-0964 | Cavia porcellus | 67.72 | 0.0 | 815 |
| LLPS-Myl-0544 | Myotis lucifugus | 67.21 | 0.0 | 830 |
| LLPS-Meg-1162 | Meleagris gallopavo | 67.11 | 0.0 | 750 |
| LLPS-Dar-3489 | Danio rerio | 65.54 | 0.0 | 765 |
| LLPS-Anc-1037 | Anolis carolinensis | 64.82 | 0.0 | 815 |
| LLPS-Dio-4313 | Dipodomys ordii | 64.55 | 2e-160 | 477 |
| LLPS-Fia-3709 | Ficedula albicollis | 64.47 | 0.0 | 732 |
| LLPS-Leo-1908 | Lepisosteus oculatus | 64.4 | 0.0 | 793 |
| LLPS-Asm-1126 | Astyanax mexicanus | 63.78 | 0.0 | 684 |
| LLPS-Xim-3039 | Xiphophorus maculatus | 63.37 | 0.0 | 758 |
| LLPS-Pof-4113 | Poecilia formosa | 63.2 | 0.0 | 749 |
| LLPS-Scf-1434 | Scleropages formosus | 62.9 | 0.0 | 760 |
| LLPS-Scm-1784 | Scophthalmus maximus | 62.14 | 0.0 | 647 |
| LLPS-Gaga-1122 | Gallus gallus | 61.99 | 0.0 | 778 |
| LLPS-Orl-3523 | Oryzias latipes | 61.23 | 0.0 | 753 |
| LLPS-Lac-2472 | Latimeria chalumnae | 61.22 | 0.0 | 749 |
| LLPS-Ten-3146 | Tetraodon nigroviridis | 61.17 | 0.0 | 556 |
| LLPS-Orn-0457 | Oreochromis niloticus | 60.58 | 0.0 | 748 |
| LLPS-Gaa-3289 | Gasterosteus aculeatus | 59.5 | 0.0 | 730 |
| LLPS-Icp-3577 | Ictalurus punctatus | 59.34 | 0.0 | 738 |
| LLPS-Tar-1325 | Takifugu rubripes | 59.06 | 0.0 | 580 |
| LLPS-Xet-1522 | Xenopus tropicalis | 57.51 | 0.0 | 709 |
| LLPS-Tag-0785 | Taeniopygia guttata | 56.85 | 0.0 | 650 |
| LLPS-Cis-1660 | Ciona savignyi | 55.71 | 6e-47 | 167 |
| LLPS-Cii-2074 | Ciona intestinalis | 49.46 | 9e-144 | 433 |
| LLPS-Org-1022 | Oryza glaberrima | 47.1 | 1e-31 | 127 |
| LLPS-Abg-0958 | Absidia glauca | 42.37 | 9e-110 | 347 |
| LLPS-Gas-0829 | Galdieria sulphuraria | 40.87 | 7e-93 | 301 |
| LLPS-Brn-2401 | Brassica napus | 38.29 | 7e-82 | 272 |
| LLPS-Bro-2605 | Brassica oleracea | 38.29 | 9e-82 | 272 |
| LLPS-Prp-1626 | Prunus persica | 38.18 | 3e-80 | 268 |
| LLPS-Via-0629 | Vigna angularis | 38.01 | 1e-75 | 256 |
| LLPS-Mua-1914 | Musa acuminata | 37.56 | 1e-78 | 264 |
| LLPS-Cus-2003 | Cucumis sativus | 37.47 | 5e-78 | 262 |
| LLPS-Art-2885 | Arabidopsis thaliana | 37.47 | 2e-82 | 273 |
| LLPS-Arl-1606 | Arabidopsis lyrata | 37.39 | 6e-80 | 267 |
| LLPS-Viv-1889 | Vitis vinifera | 37.39 | 3e-77 | 260 |
| LLPS-Sol-1693 | Solanum lycopersicum | 37.16 | 6e-77 | 259 |
| LLPS-Dac-1615 | Daucus carota | 37.05 | 3e-77 | 259 |
| LLPS-Hea-1071 | Helianthus annuus | 36.79 | 4e-81 | 270 |
| LLPS-Met-1828 | Medicago truncatula | 36.57 | 5e-75 | 254 |
| LLPS-Phv-1192 | Phaseolus vulgaris | 36.48 | 1e-74 | 253 |
| LLPS-Sei-1520 | Setaria italica | 36.4 | 7e-80 | 268 |
| LLPS-Brr-1777 | Brassica rapa | 36.38 | 9e-77 | 259 |
| LLPS-Osl-1165 | Ostreococcus lucimarinus | 36.18 | 6e-82 | 273 |
| LLPS-Nia-2229 | Nicotiana attenuata | 36.18 | 1e-80 | 269 |
| LLPS-Mae-0808 | Manihot esculenta | 36.18 | 4e-76 | 257 |
| LLPS-Sob-2056 | Sorghum bicolor | 35.96 | 1e-76 | 258 |
| LLPS-Brd-1408 | Brachypodium distachyon | 35.87 | 2e-76 | 258 |
| LLPS-Tra-1811 | Triticum aestivum | 35.87 | 2e-75 | 256 |
| LLPS-Hov-0409 | Hordeum vulgare | 35.71 | 1e-65 | 230 |
| LLPS-Pot-1693 | Populus trichocarpa | 35.7 | 4e-78 | 262 |
| LLPS-Gor-2065 | Gossypium raimondii | 35.44 | 1e-75 | 255 |
| LLPS-Orp-1645 | Oryza punctata | 35.43 | 3e-74 | 253 |
| LLPS-Zem-1811 | Zea mays | 35.36 | 5e-74 | 252 |
| LLPS-Ori-1021 | Oryza indica | 35.2 | 1e-72 | 248 |
| LLPS-Orm-1304 | Oryza meridionalis | 35.2 | 2e-73 | 250 |
| LLPS-Orr-0183 | Oryza rufipogon | 35.2 | 1e-71 | 248 |
| LLPS-Ors-0737 | Oryza sativa | 35.2 | 1e-72 | 248 |
| LLPS-Thc-2052 | Theobroma cacao | 34.99 | 8e-72 | 245 |
| LLPS-Orgl-0895 | Oryza glumaepatula | 34.98 | 2e-71 | 247 |
| LLPS-Orb-2316 | Oryza barthii | 34.98 | 1e-71 | 248 |
| LLPS-Orni-2246 | Oryza nivara | 34.98 | 9e-72 | 248 |
| LLPS-Php-1809 | Physcomitrella patens | 34.84 | 9e-76 | 256 |
| LLPS-Orbr-1888 | Oryza brachyantha | 34.75 | 1e-72 | 248 |
| LLPS-Coc-0079 | Corchorus capsularis | 34.71 | 1e-58 | 208 |
| LLPS-Amt-1829 | Amborella trichopoda | 34.38 | 1e-71 | 245 |
| LLPS-Glm-1802 | Glycine max | 34.08 | 2e-77 | 261 |
| LLPS-Sem-0725 | Selaginella moellendorffii | 33.93 | 6e-64 | 224 |
| LLPS-Cym-0996 | Cyanidioschyzon merolae | 33.86 | 1e-81 | 273 |
| LLPS-Vir-0582 | Vigna radiata | 33.8 | 1e-64 | 228 |
| LLPS-Lep-0833 | Leersia perrieri | 33.18 | 1e-63 | 223 |
| LLPS-Cae-1357 | Caenorhabditis elegans | 33.11 | 1e-59 | 215 |
| LLPS-Sot-2261 | Solanum tuberosum | 32.81 | 3e-57 | 209 |
| LLPS-Mel-0341 | Melampsora laricipopulina | 32.73 | 3e-08 | 60.5 |
| LLPS-Tru-0209 | Triticum urartu | 32.57 | 3e-63 | 222 |
| LLPS-Chc-0899 | Chondrus crispus | 29.72 | 9e-41 | 160 |
| LLPS-Chr-1659 | Chlamydomonas reinhardtii | 29.07 | 8e-63 | 228 |
| LLPS-Drm-0969 | Drosophila melanogaster | 28.88 | 2e-21 | 100 |