LLPS-Pat-2925
PARG
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Poly(ADP-ribose) glycohydrolase |
| Gene Name: | PARG |
| Ensembl Gene: | ENSPTRG00000031332.4 |
| Ensembl Protein: | ENSPTRP00000058989.3 |
| Organism: | Pan troglodytes |
| Taxa ID: | 9598 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body, Stress granule | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPTRT00000067401.3 | ENSPTRP00000058989.3 |
| UniProt | H2RDJ6, H2RDJ6_PANTR | |
| GeneBank | AC183834, AACZ04060518 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MNAGPGCEPC TKRPRWGAAT NSPAASDARS FPSRQRRVLD PKDAHVQFRV PPSSPACVPG 60 61 RAGQHRGSAT SLVFKQKTIT SWMDTKGIKT VESDSLDSKE NNNTRIESMM SSVQKDNFYQ 120 121 PNVEKLENVS QLSLDKSPTV KSTQCLNQHQ TAAMCKWQNE GKHTERLLES EPQTVTLVPE 180 181 QFSNANIDRQ QFLTTVKLAN AKQTTEDEQA REAKSHQKCS KSCHPGEDCA SCQQDEIDMV 240 241 PESPLSDVGS EDVGTGPKND NKLIRQESCL GNSPPFEKES EPESPMDVDN SKNSCQDSEA 300 301 DEETSPGFDE QEDGSSSQTA NKPSRFQARD ADIEFRKRYS TKGGEVRLHF QFEGGESRTG 360 361 MNDLNAKLPG NISSLNVECR NSKQHGKKDS KITDHFMRLP KAEDRRKEQW ETKHQRTERK 420 421 IPKYVPPHLS PDKKWLGTPI EEMRRMPRCG IRLPLLRPSA NHTVTIRVDL LRAGEVPKPF 480 481 PTHYKDLWDN KRVKMPCSEQ NLYPVEDENG ERTAGSRWEL IQTALLNKFT RPQNLKDAIL 540 541 KYNVAYSKKW DFTALIDFWD KVKVSLFLYE NIINNSIRRL FEGRSSRKPE KLKTLFCYFR 600 601 RVTEKKPTGL VTFTRQSLED FPEWERCEKP LTRLHVTYEG TIEENGRGML QVDFANCFVG 660 661 GGVTSAGLVQ EEIRFLINPE LIVSRLFTEV LDYNECLIIT GTEQYSEYTG YAETYHWSRS 720 721 HEDGSERDDW QRRCTEIVAI DALHFRRYLD QFVPEKMRRE LNKAYCGFLR PGVSSENLSA 780 781 VATGNWGCGA FGGDARLKAL IQILAAAAAE RDVVYFTFGD SELMRDIYSM HIFLTERKLT 840 841 VGDVYKLLLR YYNEECRNCS TPGPDIKLYP FIYHAVESCA ETADHSGQRT GT 892 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAATGCGG GCCCCGGCTG TGAACCCTGC ACCAAGCGAC CCCGCTGGGG CGCCGCTACA 60 61 AATTCGCCGG CTGCTTCGGA CGCCCGGAGC TTTCCCAGCA GGCAGAGGCG CGTCCTCGAC 120 121 CCCAAGGACG CTCACGTGCA GTTCAGGGTC CCACCGTCCT CGCCAGCCTG CGTCCCAGGG 180 181 CGGGCGGGAC AGCACAGAGG CAGCGCCACC TCGCTTGTTT TCAAACAAAA AACTATTACC 240 241 AGTTGGATGG ACACTAAAGG AATCAAGACA GTGGAATCAG ACAGTTTGGA TAGTAAAGAA 300 301 AACAACAATA CAAGAATAGA ATCCATGATG AGTTCTGTAC AAAAAGATAA CTTTTACCAA 360 361 CCTAATGTAG AAAAATTAGA AAATGTTTCT CAGCTAAGTC TTGATAAGTC ACCCACTGTA 420 421 AAAAGTACAC AGTGTTTGAA CCAGCATCAG ACTGCAGCAA TGTGTAAGTG GCAAAATGAA 480 481 GGGAAACACA CGGAGCGGCT TTTGGAAAGT GAACCTCAAA CAGTAACCCT GGTACCAGAG 540 541 CAGTTTAGTA ATGCTAACAT TGATCGACAA CAGTTTCTCA CAACTGTAAA GCTTGCAAAT 600 601 GCAAAGCAGA CTACGGAAGA TGAACAGGCC AGAGAAGCCA AAAGCCACCA GAAGTGCAGC 660 661 AAGTCTTGCC ATCCTGGGGA AGACTGTGCA AGTTGTCAGC AAGATGAGAT AGACATGGTG 720 721 CCAGAGAGTC CATTGTCAGA TGTTGGCTCT GAGGATGTTG GTACTGGGCC AAAAAATGAC 780 781 AACAAATTGA TTAGACAAGA AAGTTGCCTA GGAAATTCTC CTCCATTTGA GAAGGAAAGT 840 841 GAACCCGAGT CACCGATGGA TGTGGATAAT TCTAAAAATA GTTGTCAAGA CTCAGAAGCA 900 901 GATGAGGAGA CAAGTCCAGG TTTTGATGAA CAAGAAGATG GTAGTTCCTC CCAAACAGCA 960 961 AATAAACCTT CAAGGTTCCA AGCAAGAGAC GCTGACATTG AATTTAGGAA ACGGTACTCT 1020 1021 ACTAAGGGCG GTGAAGTTAG ATTACATTTC CAGTTTGAAG GAGGAGAGAG TCGCACTGGA 1080 1081 ATGAATGATT TAAATGCTAA ACTACCTGGA AATATTTCTA GCCTGAATGT AGAATGCAGA 1140 1141 AATTCTAAGC AACATGGAAA AAAGGATTCT AAAATCACAG ATCATTTCAT GAGACTGCCC 1200 1201 AAAGCAGAGG ACAGAAGAAA AGAACAATGG GAAACCAAAC ATCAAAGAAC AGAAAGGAAG 1260 1261 ATCCCTAAAT ACGTTCCGCC TCACCTTTCT CCAGATAAGA AGTGGCTTGG AACTCCCATT 1320 1321 GAGGAGATGA GAAGAATGCC TCGGTGTGGG ATCCGGCTGC CTCTCTTGAG ACCATCTGCC 1380 1381 AATCACACAG TAACTATTCG GGTAGATCTT TTGCGAGCAG GAGAAGTTCC TAAACCTTTT 1440 1441 CCAACACATT ATAAAGATTT GTGGGATAAC AAGCGTGTTA AAATGCCTTG TTCAGAACAA 1500 1501 AATTTGTACC CAGTGGAAGA TGAGAATGGT GAGCGAACTG CGGGGAGCCG GTGGGAGCTC 1560 1561 ATTCAGACTG CACTTCTCAA CAAATTTACA CGACCCCAAA ACTTGAAGGA TGCTATTCTG 1620 1621 AAATACAATG TGGCATATTC TAAGAAATGG GACTTTACAG CTTTGATCGA TTTCTGGGAT 1680 1681 AAGGTAAAAG TATCCTTATT TCTTTATGAA AATATTATTA ACAACTCAAT AAGAAGATTG 1740 1741 TTTGAGGGAC GTTCATCAAG GAAACCGGAG AAACTTAAAA CGCTCTTCTG CTACTTTAGA 1800 1801 AGAGTCACAG AGAAAAAACC TACTGGGTTG GTGACATTTA CAAGACAGAG TCTTGAAGAT 1860 1861 TTTCCAGAAT GGGAAAGATG TGAAAAACCC TTGACACGAT TGCATGTCAC TTACGAAGGT 1920 1921 ACCATAGAAG AAAATGGCCG AGGCATGCTA CAGGTGGATT TTGCAAATTG TTTTGTTGGA 1980 1981 GGTGGTGTAA CCAGTGCAGG ACTTGTGCAA GAAGAAATCC GCTTTTTAAT CAATCCTGAG 2040 2041 TTGATTGTTT CACGGCTCTT CACTGAGGTG CTGGATTACA ATGAATGTCT AATTATCACA 2100 2101 GGTACTGAGC AGTACAGTGA ATACACAGGC TATGCTGAGA CATATCATTG GTCCCGGAGC 2160 2161 CACGAAGATG GGAGTGAAAG GGACGACTGG CAGCGGCGCT GCACTGAGAT CGTTGCCATT 2220 2221 GATGCTCTTC ACTTCAGACG CTACCTCGAT CAGTTTGTGC CTGAGAAAAT GAGACGCGAG 2280 2281 CTGAACAAGG CTTACTGTGG ATTTCTCCGT CCTGGAGTTT CTTCAGAGAA TCTTTCTGCA 2340 2341 GTGGCCACAG GAAACTGGGG CTGTGGTGCC TTTGGGGGTG ATGCCAGGTT AAAAGCCTTA 2400 2401 ATACAGATAT TGGCAGCTGC TGCAGCTGAG CGAGATGTGG TTTATTTCAC CTTTGGGGAC 2460 2461 TCAGAATTGA TGAGAGACAT TTACAGCATG CACATTTTCC TTACTGAAAG GAAACTCACT 2520 2521 GTTGGAGATG TGTATAAGCT GTTGCTACGA TACTACAATG AAGAATGCAG AAACTGTTCC 2580 2581 ACCCCTGGAC CAGACATCAA GCTTTATCCA TTCATATACC ATGCTGTCGA GTCCTGTGCA 2640 2641 GAGACTGCTG ACCATTCAGG GCAAAGGACA GGGACCTGA 2679 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Gog-3683 | Gorilla gorilla | 94.52 | 1e-40 | 150 |
| LLPS-Hos-1498 | Homo sapiens | 86.58 | 0.0 | 1635 |
| LLPS-Poa-0597 | Pongo abelii | 86.07 | 0.0 | 1622 |
| LLPS-Nol-3164 | Nomascus leucogenys | 85.45 | 0.0 | 1614 |
| LLPS-Maf-2783 | Macaca fascicularis | 85.25 | 0.0 | 1610 |
| LLPS-Paa-0721 | Papio anubis | 85.14 | 0.0 | 1608 |
| LLPS-Mal-2561 | Mandrillus leucophaeus | 85.14 | 0.0 | 1607 |
| LLPS-Cea-3072 | Cercocebus atys | 85.04 | 0.0 | 1607 |
| LLPS-Man-3429 | Macaca nemestrina | 85.04 | 0.0 | 1602 |
| LLPS-Mam-4076 | Macaca mulatta | 85.04 | 0.0 | 1605 |
| LLPS-Chs-0370 | Chlorocebus sabaeus | 84.94 | 0.0 | 1603 |
| LLPS-Rhb-0512 | Rhinopithecus bieti | 84.73 | 0.0 | 1591 |
| LLPS-Caj-2627 | Callithrix jacchus | 83.09 | 0.0 | 1565 |
| LLPS-Cas-0595 | Carlito syrichta | 80.76 | 0.0 | 1501 |
| LLPS-Sus-0598 | Sus scrofa | 80.31 | 0.0 | 1474 |
| LLPS-Mea-3560 | Mesocricetus auratus | 80.16 | 0.0 | 797 |
| LLPS-Aon-2891 | Aotus nancymaae | 80.05 | 0.0 | 1303 |
| LLPS-Eqc-0293 | Equus caballus | 79.32 | 0.0 | 1479 |
| LLPS-Fec-1157 | Felis catus | 79.2 | 0.0 | 1491 |
| LLPS-Urm-3744 | Ursus maritimus | 79.18 | 0.0 | 1361 |
| LLPS-Mup-4219 | Mustela putorius furo | 78.81 | 0.0 | 1467 |
| LLPS-Otg-3402 | Otolemur garnettii | 78.53 | 0.0 | 1454 |
| LLPS-Caf-3989 | Canis familiaris | 78.51 | 0.0 | 1464 |
| LLPS-Ict-1968 | Ictidomys tridecemlineatus | 78.2 | 0.0 | 1487 |
| LLPS-Bot-4479 | Bos taurus | 77.99 | 0.0 | 1452 |
| LLPS-Myl-2890 | Myotis lucifugus | 76.79 | 0.0 | 1434 |
| LLPS-Orc-1902 | Oryctolagus cuniculus | 76.69 | 0.0 | 1429 |
| LLPS-Ova-2266 | Ovis aries | 76.58 | 0.0 | 1415 |
| LLPS-Xet-0197 | Xenopus tropicalis | 76.47 | 4e-16 | 86.3 |
| LLPS-Aim-3749 | Ailuropoda melanoleuca | 75.71 | 0.0 | 697 |
| LLPS-Fud-1949 | Fukomys damarensis | 75.13 | 0.0 | 1404 |
| LLPS-Mum-4617 | Mus musculus | 74.41 | 0.0 | 1352 |
| LLPS-Loa-4391 | Loxodonta africana | 74.23 | 0.0 | 1377 |
| LLPS-Cap-1884 | Cavia porcellus | 73.54 | 0.0 | 1378 |
| LLPS-Ran-2963 | Rattus norvegicus | 72.32 | 0.0 | 1334 |
| LLPS-Lac-3175 | Latimeria chalumnae | 71.92 | 2e-150 | 468 |
| LLPS-Dio-0711 | Dipodomys ordii | 69.46 | 0.0 | 1231 |
| LLPS-Xim-3463 | Xiphophorus maculatus | 66.24 | 3e-136 | 432 |
| LLPS-Mod-2230 | Monodelphis domestica | 62.6 | 0.0 | 1089 |
| LLPS-Sah-0935 | Sarcophilus harrisii | 61.79 | 0.0 | 1073 |
| LLPS-Gaga-3966 | Gallus gallus | 55.81 | 0.0 | 869 |
| LLPS-Gaa-2829 | Gasterosteus aculeatus | 55.77 | 4e-161 | 487 |
| LLPS-Cis-0206 | Ciona savignyi | 55.63 | 2e-87 | 292 |
| LLPS-Pes-1649 | Pelodiscus sinensis | 55.54 | 0.0 | 885 |
| LLPS-Fia-0071 | Ficedula albicollis | 55.49 | 0.0 | 830 |
| LLPS-Orn-4104 | Oreochromis niloticus | 54.21 | 4e-174 | 523 |
| LLPS-Scm-2483 | Scophthalmus maximus | 54.07 | 2e-173 | 530 |
| LLPS-Scf-1864 | Scleropages formosus | 53.65 | 0.0 | 564 |
| LLPS-Icp-1634 | Ictalurus punctatus | 53.31 | 3e-165 | 509 |
| LLPS-Orl-0821 | Oryzias latipes | 52.63 | 1e-171 | 524 |
| LLPS-Tar-2384 | Takifugu rubripes | 52.32 | 2e-164 | 505 |
| LLPS-Asm-3263 | Astyanax mexicanus | 52.3 | 2e-167 | 517 |
| LLPS-Anp-2275 | Anas platyrhynchos | 51.89 | 6e-141 | 438 |
| LLPS-Leo-2942 | Lepisosteus oculatus | 51.56 | 2e-175 | 540 |
| LLPS-Pof-1121 | Poecilia formosa | 51.54 | 5e-166 | 509 |
| LLPS-Dar-3179 | Danio rerio | 50.49 | 3e-141 | 445 |
| LLPS-Ten-3625 | Tetraodon nigroviridis | 50.1 | 8e-132 | 411 |
| LLPS-Ora-1926 | Ornithorhynchus anatinus | 47.27 | 2e-124 | 392 |
| LLPS-Drm-1948 | Drosophila melanogaster | 45.62 | 1e-64 | 236 |
| LLPS-Tag-3576 | Taeniopygia guttata | 44.5 | 0.0 | 596 |
| LLPS-Anc-3095 | Anolis carolinensis | 44.05 | 0.0 | 625 |
| LLPS-Sem-1407 | Selaginella moellendorffii | 43.68 | 3e-46 | 178 |
| LLPS-Nia-1698 | Nicotiana attenuata | 41.58 | 1e-32 | 137 |
| LLPS-Mae-0980 | Manihot esculenta | 41.0 | 2e-35 | 146 |
| LLPS-Pot-2598 | Populus trichocarpa | 40.8 | 8e-35 | 144 |
| LLPS-Sol-1597 | Solanum lycopersicum | 40.53 | 1e-32 | 138 |
| LLPS-Thc-2384 | Theobroma cacao | 40.39 | 6e-36 | 148 |
| LLPS-Amt-1215 | Amborella trichopoda | 40.31 | 2e-30 | 132 |
| LLPS-Viv-0426 | Vitis vinifera | 40.3 | 2e-35 | 146 |
| LLPS-Brn-2653 | Brassica napus | 39.59 | 3e-48 | 184 |
| LLPS-Brr-1306 | Brassica rapa | 39.59 | 5e-48 | 184 |
| LLPS-Sot-2117 | Solanum tuberosum | 39.47 | 8e-30 | 129 |
| LLPS-Php-0978 | Physcomitrella patens | 39.37 | 3e-43 | 169 |
| LLPS-Prp-0334 | Prunus persica | 39.11 | 6e-30 | 129 |
| LLPS-Bro-2809 | Brassica oleracea | 38.97 | 2e-47 | 181 |
| LLPS-Orbr-2236 | Oryza brachyantha | 38.24 | 3e-47 | 180 |
| LLPS-Orp-0445 | Oryza punctata | 38.02 | 2e-47 | 179 |
| LLPS-Orm-1477 | Oryza meridionalis | 38.02 | 9e-48 | 182 |
| LLPS-Tru-1458 | Triticum urartu | 37.98 | 6e-35 | 140 |
| LLPS-Brd-2333 | Brachypodium distachyon | 37.82 | 8e-45 | 174 |
| LLPS-Orni-2229 | Oryza nivara | 37.7 | 1e-46 | 179 |
| LLPS-Orb-1781 | Oryza barthii | 37.7 | 9e-47 | 179 |
| LLPS-Ori-2342 | Oryza indica | 37.7 | 1e-46 | 179 |
| LLPS-Orgl-2179 | Oryza glumaepatula | 37.7 | 6e-47 | 180 |
| LLPS-Org-1491 | Oryza glaberrima | 37.7 | 9e-47 | 179 |
| LLPS-Orr-1272 | Oryza rufipogon | 37.7 | 1e-46 | 179 |
| LLPS-Sei-1700 | Setaria italica | 37.01 | 3e-48 | 184 |
| LLPS-Zem-0383 | Zea mays | 36.99 | 3e-43 | 170 |
| LLPS-Dac-2416 | Daucus carota | 36.98 | 8e-35 | 143 |
| LLPS-Lep-1558 | Leersia perrieri | 36.56 | 1e-43 | 171 |
| LLPS-Hov-0029 | Hordeum vulgare | 36.42 | 2e-42 | 167 |
| LLPS-Sob-2528 | Sorghum bicolor | 36.36 | 1e-44 | 173 |
| LLPS-Met-2141 | Medicago truncatula | 35.84 | 6e-46 | 177 |
| LLPS-Cus-1686 | Cucumis sativus | 35.82 | 1e-43 | 169 |
| LLPS-Tra-1305 | Triticum aestivum | 35.82 | 1e-41 | 165 |
| LLPS-Cae-0950 | Caenorhabditis elegans | 35.77 | 4e-33 | 139 |
| LLPS-Vir-1321 | Vigna radiata | 35.57 | 5e-43 | 170 |
| LLPS-Via-2344 | Vigna angularis | 35.29 | 1e-43 | 171 |
| LLPS-Mua-1858 | Musa acuminata | 34.91 | 4e-39 | 157 |
| LLPS-Glm-0671 | Glycine max | 34.73 | 2e-44 | 173 |
| LLPS-Gor-2049 | Gossypium raimondii | 34.57 | 8e-44 | 171 |
| LLPS-Phv-1942 | Phaseolus vulgaris | 34.17 | 3e-44 | 173 |
| LLPS-Hea-0718 | Helianthus annuus | 34.01 | 3e-42 | 167 |
| LLPS-Cii-2031 | Ciona intestinalis | 33.23 | 2e-34 | 143 |
| LLPS-Arl-2101 | Arabidopsis lyrata | 33.12 | 2e-37 | 152 |
| LLPS-Art-2374 | Arabidopsis thaliana | 31.8 | 3e-35 | 145 |
| LLPS-Zyt-1535 | Zymoseptoria tritici | 29.41 | 3e-06 | 54.7 |