LLPS-Pat-1685
HAP1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Huntingtin associated protein 1 |
| Gene Name: | HAP1 |
| Ensembl Gene: | ENSPTRG00000009177.5 |
| Ensembl Protein: | ENSPTRP00000093060.1 |
| Organism: | Pan troglodytes |
| Taxa ID: | 9598 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPTRT00000092825.1 | ENSPTRP00000093060.1 |
| Ensembl | ENSPTRT00000016886.4 | ENSPTRP00000015630.4 |
| Ensembl | ENSPTRT00000016887.4 | ENSPTRP00000015631.4 |
| UniProt | H2QD01, H2QD01_PANTR | |
| GeneBank | AACZ04038960 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MRPKRSGRCC AGSRLGPGDP AALTCAPSPS ASPAPEPSAQ PQARGTGQRA GSLAASGSQF 60 61 LSEARTGARP ASEAGAKAGA RRPSAFSAIQ GDVRSMPDNS DAPWTRFVFQ GPFGSRATGR 120 121 GTGKAAGIWK TPASYVGRRP GVSGPERAAF IRELEEALCP NLPLPVKKIT QEDVKVMLYL 180 181 LEELLPPVWE SVTYGMVLLQ RERDLNTAAR IGQSLVKQNS VLMEENSKLE ALLGSAKEEI 240 241 LHLRHQVNLR DELLQLYSDS DEEDEDEEEE EEEEQEEEEA EEDQQCAHPC DAPKLILQEA 300 301 LLHQHHCPQL EALQEKLRLL EEENHQLREE ASQLDTLEDE EQMLILECVE QFSEASQQMA 360 361 ELSEVLVLRL ENYERQQQEV ARLQAQVLKL QQRCRMYGAE TEKLQKQLAS EKEIQMQLQE 420 421 ESVWVGSQLQ DLREKYMDCG GMLIETQEEV KTLRQQPPVS TGSATHYPYS VPLETLPGFQ 480 481 ETLAEERRTS LRRMISDPVY FMERNYEMPR GDTSSLRYDF RYSEDREQVQ GFEAEEGLML 540 541 AADIMRGEDF TPAEELVPQE ELGAAKKVPA EEGVMEEAEL VSEETEGWEE VELELDEATR 600 601 MNVVTSALEA SGLGPSHLDM NYVLQQLANW QDAHYRRQLR WKMLQKSECP HGALPAASRT 660 661 SCRSSCR 667 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCGCCCGA AGAGGTCGGG CCGGTGCTGC GCGGGGAGCC GGCTCGGACC CGGGGACCCA 60 61 GCAGCCCTCA CCTGTGCACC TTCGCCCTCA GCCAGTCCCG CTCCGGAGCC CTCTGCGCAG 120 121 CCGCAGGCAC GGGGCACTGG ACAGAGAGCA GGATCCCTAG CCGCCTCTGG ATCCCAGTTC 180 181 CTCTCGGAAG CCCGCACCGG AGCTCGCCCG GCCTCCGAGG CTGGAGCCAA GGCAGGAGCC 240 241 CGGCGCCCGT CCGCATTCTC GGCCATCCAA GGGGATGTCC GGTCTATGCC CGACAATTCG 300 301 GACGCGCCGT GGACCCGCTT CGTATTCCAA GGGCCGTTTG GTTCCCGGGC CACTGGCCGG 360 361 GGGACTGGAA AGGCAGCGGG CATCTGGAAG ACGCCAGCCT CCTACGTTGG CCGGCGACCC 420 421 GGGGTGTCCG GCCCTGAGCG CGCCGCCTTT ATTCGGGAGC TGGAGGAAGC ACTGTGTCCT 480 481 AACCTACCTC TGCCAGTCAA AAAGATCACC CAGGAAGACG TCAAAGTGAT GTTATATTTG 540 541 CTGGAGGAGC TTCTCCCACC TGTCTGGGAG AGCGTTACCT ATGGGATGGT CCTTCTGCAG 600 601 AGAGAGAGGG ACCTGAACAC TGCAGCTCGC ATTGGCCAGT CCCTGGTGAA ACAGAACAGT 660 661 GTTTTGATGG AGGAGAACAG CAAGCTGGAA GCCCTGCTGG GCTCAGCCAA GGAGGAGATT 720 721 TTACACCTCA GACACCAGGT GAACTTGCGG GATGAGCTCC TCCAGCTCTA CTCAGATTCT 780 781 GATGAGGAGG ATGAGGATGA AGAAGAGGAG GAGGAAGAGG AACAGGAAGA AGAGGAAGCA 840 841 GAGGAAGACC AGCAGTGTGC TCATCCCTGT GATGCCCCTA AGCTGATTTT GCAGGAGGCA 900 901 TTGCTGCACC AGCACCACTG CCCACAGCTG GAAGCCTTGC AGGAGAAGCT GAGGCTGCTG 960 961 GAGGAGGAGA ATCATCAGCT GAGAGAAGAG GCCTCTCAAC TCGACACTCT TGAGGATGAG 1020 1021 GAACAGATGC TCATTCTGGA GTGTGTGGAG CAGTTTTCGG AGGCCAGCCA ACAGATGGCT 1080 1081 GAGCTGTCAG AGGTGCTGGT GCTCAGGCTG GAAAACTATG AACGGCAGCA GCAGGAGGTC 1140 1141 GCTCGGCTGC AGGCCCAGGT GCTGAAGCTG CAGCAGCGCT GCCGGATGTA TGGGGCTGAG 1200 1201 ACTGAAAAGT TGCAGAAGCA GCTGGCTTCA GAGAAGGAAA TCCAGATGCA GCTCCAGGAA 1260 1261 GAGAGCGTGT GGGTGGGTTC CCAGCTGCAG GACCTGCGGG AGAAGTACAT GGATTGTGGG 1320 1321 GGCATGCTGA TTGAGACGCA GGAGGAGGTG AAGACCCTCC GCCAGCAACC CCCGGTGTCC 1380 1381 ACTGGGTCTG CCACCCATTA CCCATACAGC GTGCCTCTGG AGACTCTTCC TGGTTTCCAG 1440 1441 GAGACGCTGG CTGAGGAGCG CAGAACGTCT CTAAGGAGGA TGATCTCAGA CCCTGTGTAT 1500 1501 TTTATGGAGA GGAATTATGA GATGCCCAGA GGGGACACAT CCAGCCTAAG GTATGATTTT 1560 1561 CGCTACAGTG AGGATCGAGA GCAGGTGCAG GGGTTTGAGG CTGAGGAAGG GTTGATGCTG 1620 1621 GCAGCGGATA TTATGCGGGG GGAAGATTTC ACGCCTGCGG AGGAGTTGGT GCCCCAGGAG 1680 1681 GAGCTGGGGG CTGCCAAGAA GGTGCCGGCT GAGGAAGGGG TGATGGAAGA GGCAGAGCTG 1740 1741 GTGTCAGAGG AGACCGAGGG CTGGGAGGAG GTGGAACTGG AGCTGGATGA GGCAACGCGG 1800 1801 ATGAACGTGG TGACATCAGC CCTGGAGGCC AGCGGCTTGG GCCCTTCACA CCTGGACATG 1860 1861 AATTATGTCC TCCAGCAGCT GGCCAACTGG CAAGATGCCC ATTACAGGCG GCAGCTGAGG 1920 1921 TGGAAGATGC TCCAGAAAAG TGAGTGCCCC CACGGGGCCC TCCCTGCCGC CAGCCGGACA 1980 1981 AGCTGCAGAT CGTCGTGCCG ATGA 2004 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Pap-1778 | Pan paniscus | 98.48 | 0.0 | 1113 |
| LLPS-Gog-1066 | Gorilla gorilla | 97.05 | 0.0 | 556 |
| LLPS-Hos-2545 | Homo sapiens | 96.22 | 0.0 | 1078 |
| LLPS-Poa-2201 | Pongo abelii | 91.48 | 0.0 | 1007 |
| LLPS-Nol-4300 | Nomascus leucogenys | 87.65 | 0.0 | 915 |
| LLPS-Cea-0534 | Cercocebus atys | 86.75 | 2e-63 | 225 |
| LLPS-Paa-3738 | Papio anubis | 85.79 | 5e-81 | 273 |
| LLPS-Mal-3942 | Mandrillus leucophaeus | 84.62 | 7e-55 | 200 |
| LLPS-Rhb-1014 | Rhinopithecus bieti | 82.7 | 0.0 | 885 |
| LLPS-Man-4575 | Macaca nemestrina | 75.68 | 4e-147 | 444 |
| LLPS-Otg-3806 | Otolemur garnettii | 74.06 | 0.0 | 741 |
| LLPS-Ict-1225 | Ictidomys tridecemlineatus | 71.66 | 0.0 | 712 |
| LLPS-Tut-2233 | Tursiops truncatus | 70.86 | 0.0 | 736 |
| LLPS-Sus-2897 | Sus scrofa | 69.97 | 0.0 | 658 |
| LLPS-Maf-3363 | Macaca fascicularis | 69.24 | 0.0 | 676 |
| LLPS-Mam-4064 | Macaca mulatta | 68.94 | 0.0 | 671 |
| LLPS-Cas-0432 | Carlito syrichta | 67.83 | 0.0 | 676 |
| LLPS-Dio-2656 | Dipodomys ordii | 65.31 | 0.0 | 585 |
| LLPS-Aim-2162 | Ailuropoda melanoleuca | 63.4 | 0.0 | 573 |
| LLPS-Caf-0236 | Canis familiaris | 62.67 | 0.0 | 621 |
| LLPS-Ran-1628 | Rattus norvegicus | 62.46 | 0.0 | 543 |
| LLPS-Mum-4637 | Mus musculus | 62.16 | 4e-175 | 521 |
| LLPS-Eqc-3916 | Equus caballus | 61.59 | 0.0 | 666 |
| LLPS-Loa-2486 | Loxodonta africana | 60.0 | 0.0 | 579 |
| LLPS-Mea-4260 | Mesocricetus auratus | 59.77 | 4e-177 | 526 |
| LLPS-Bot-1363 | Bos taurus | 55.81 | 3e-176 | 523 |