LLPS-Pat-0310
TACC3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | TACC3 isoform 3 |
| Gene Name: | TACC3, CK820_G0041071 |
| Ensembl Gene: | ENSPTRG00000015834.7 |
| Ensembl Protein: | ENSPTRP00000027263.6 |
| Organism: | Pan troglodytes |
| Taxa ID: | 9598 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Chromatin, Centrosome/Spindle pole body, Stress granule | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPTRT00000029550.6 | ENSPTRP00000027263.6 |
| Ensembl | ENSPTRT00000096703.1 | ENSPTRP00000070189.1 |
| UniProt | H2QP38, H2QP38_PANTR, A0A2J8K6P6 | |
| GeneBank | AACZ04059873, NBAG03000389 | , PNI30695.1 |
| RefSeq | XM_016951122.1 | XP_016806611.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSLQVLNDKN VSNEKNTENC DFLFSPPEVT GRSSVLHVSQ KENVPPKNLA KAMKVTFQTP 60 61 LRDPQTHRIL SPSMASKLEA PFTQDDTLGL ENSHPVWTQK ENQQLIKEVD AKTTHGILQK 120 121 PVEADTDLLG DASPAFGSGS SSESGPGALA DLDCSSSSQS PGSSENQMVS PGKVSGSPEQ 180 181 AVEENLSSYS LDRRVTPTSE TLEDPCRTES QHKAETPHGA EEECKAETPH GAEEECRHGG 240 241 VCAPTAVATS PPGAIPKEAC GGAPLQGLPG EALACPAGVG TPVPADGTQT LTCAHTSAPE 300 301 STAPTNHLVA GRAMTLSPQE EVAAGQMASS SRSGPVKLEF DVSDGATSKR APPPRRLGER 360 361 SGLKPPLRKA AARQQKAPQE VEEDDSRSGA GEDPPMPASR GSYHLDWDKM DDPNFSPFGG 420 421 DTKSGCSEAQ PPESPETRLG QPAAEQLSAG PATEEPGPCL SQQLHSASAE DTPVVQLAAE 480 481 TPTAESKERA LNSASTSLPT SCPVSEPVPT HQQGQPALEL KEESFRDPAE VLGTGAEVDY 540 541 LEQFGTSSFK ESALRKQSLY LKFDPLLRDS PRRPVPVATE TSSMHGANET PSGRPREAKL 600 601 VEFDFLGALD IPVPGPPPGV PAPGGPPLST GPIVDLLQYS QKDLDAVVKA TQEENRELRS 660 661 RCEELHGKNL ELGKIMDRFE EVVYQAMEEV QKQKELSKAE IQKVLKEKDQ LTTDLNSMEK 720 721 SFSDLFKRFE KQKEVIEGYR KNEESLKKCV EDYLARITQE GQRYQALKAH AEEKLQLANE 780 781 EIAQVRSKAQ AEALALQASL RKEQMRIQSL EKTVEQKTKE NEELTRICDD LISKMEKI 838 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGTCTGC AGGTCTTAAA CGACAAAAAT GTCAGCAATG AAAAAAATAC AGAAAATTGC 60 61 GACTTCCTGT TTTCGCCACC AGAAGTTACC GGAAGATCGT CTGTTCTTCA TGTGTCACAG 120 121 AAAGAAAATG TGCCACCCAA GAACCTGGCC AAAGCTATGA AGGTGACTTT TCAGACACCT 180 181 CTGCGGGATC CACAGACGCA CAGGATTCTA AGTCCTAGCA TGGCCAGCAA ACTTGAGGCT 240 241 CCTTTCACTC AGGATGACAC CCTTGGACTG GAAAACTCAC ACCCGGTCTG GACACAGAAA 300 301 GAGAACCAAC AGCTCATCAA GGAAGTGGAT GCCAAAACTA CTCATGGAAT TCTACAGAAA 360 361 CCAGTGGAGG CTGACACCGA CCTCCTGGGG GATGCAAGCC CAGCCTTTGG GAGTGGCAGC 420 421 TCCAGCGAGT CTGGCCCCGG TGCCCTGGCT GACCTGGACT GCTCAAGCTC TTCCCAGAGC 480 481 CCAGGAAGTT CTGAGAACCA AATGGTGTCT CCAGGAAAAG TGTCTGGCAG CCCTGAGCAA 540 541 GCCGTGGAGG AAAACCTTAG TTCCTATTCC TTAGACAGAA GAGTGACACC CACCTCTGAG 600 601 ACCCTAGAAG ACCCTTGCAG GACAGAGTCC CAGCACAAAG CGGAGACTCC GCACGGAGCC 660 661 GAGGAAGAAT GCAAAGCGGA GACTCCGCAC GGAGCCGAGG AAGAATGCCG GCACGGTGGG 720 721 GTCTGTGCTC CCACAGCAGT GGCCACTTCG CCTCCTGGTG CAATTCCTAA GGAAGCCTGC 780 781 GGAGGAGCAC CCCTGCAGGG TCTGCCTGGC GAAGCCCTGG CCTGCCCTGC GGGTGTGGGC 840 841 ACCCCCGTGC CAGCAGATGG CACTCAGACC CTTACCTGTG CACACACCTC TGCTCCTGAG 900 901 AGCACAGCCC CAACCAACCA CCTGGTGGCT GGCAGGGCCA TGACCCTGAG TCCTCAGGAA 960 961 GAAGTGGCCG CAGGCCAAAT GGCCAGCTCC TCGAGGAGCG GACCCGTAAA ACTAGAATTT 1020 1021 GATGTATCTG ATGGCGCCAC CAGCAAAAGG GCACCCCCAC CAAGGAGACT GGGAGAGAGG 1080 1081 TCCGGCCTCA AGCCTCCCTT GAGGAAAGCA GCAGCGAGGC AGCAAAAGGC CCCGCAGGAG 1140 1141 GTGGAGGAGG ATGACAGTAG GAGCGGAGCG GGAGAGGACC CCCCCATGCC GGCTTCTCGG 1200 1201 GGCTCTTACC ACCTCGACTG GGACAAAATG GATGACCCAA ACTTCAGCCC GTTCGGAGGT 1260 1261 GACACCAAGT CTGGTTGCAG TGAGGCCCAG CCCCCAGAAA GCCCTGAGAC CAGGCTGGGC 1320 1321 CAGCCAGCGG CTGAACAGCT GAGTGCTGGG CCTGCCACGG AGGAGCCAGG TCCCTGTCTG 1380 1381 AGCCAGCAGC TGCATTCAGC CTCAGCGGAG GACACGCCTG TGGTGCAGTT GGCAGCCGAG 1440 1441 ACCCCAACAG CAGAGAGCAA GGAGAGAGCC TTGAACTCTG CCAGCACCTC GCTTCCCACA 1500 1501 AGCTGTCCAG TCAGTGAGCC AGTGCCCACC CATCAGCAGG GGCAGCCTGC CTTGGAGCTG 1560 1561 AAAGAGGAGA GCTTCAGAGA CCCCGCTGAG GTTCTAGGCA CGGGCGCGGA GGTGGATTAC 1620 1621 CTGGAGCAGT TTGGAACTTC CTCGTTTAAG GAGTCAGCCT TGAGGAAGCA GTCCTTATAC 1680 1681 CTCAAGTTCG ACCCCCTCCT GAGGGACAGT CCTCGTAGAC CAGTGCCCGT GGCCACCGAG 1740 1741 ACCAGCAGCA TGCACGGTGC AAATGAGACT CCCTCAGGAC GTCCGCGGGA AGCCAAGCTT 1800 1801 GTGGAGTTCG ATTTCTTGGG AGCACTGGAC ATTCCTGTGC CAGGCCCACC CCCAGGTGTC 1860 1861 CCCGCACCTG GGGGCCCACC CCTGTCCACC GGACCTATAG TGGACCTGCT CCAGTACAGC 1920 1921 CAGAAGGACC TGGATGCAGT GGTAAAGGCG ACACAGGAGG AGAACCGGGA GCTGAGGAGC 1980 1981 AGGTGTGAGG AGCTCCACGG GAAGAACCTG GAACTGGGGA AGATCATGGA CAGGTTCGAA 2040 2041 GAGGTTGTGT ACCAGGCCAT GGAGGAAGTT CAGAAGCAGA AGGAACTTTC CAAAGCTGAA 2100 2101 ATCCAGAAAG TTCTAAAAGA AAAAGACCAA CTTACCACAG ATCTGAACTC CATGGAGAAG 2160 2161 TCCTTCTCCG ACCTCTTCAA GCGTTTTGAG AAACAGAAAG AGGTGATCGA GGGCTACCGC 2220 2221 AAGAACGAAG AGTCACTGAA GAAGTGCGTG GAGGATTACC TGGCGAGGAT CACCCAGGAA 2280 2281 GGCCAGAGGT ACCAAGCCCT GAAGGCCCAC GCGGAGGAGA AGCTGCAGCT GGCAAACGAG 2340 2341 GAGATCGCCC AGGTCCGGAG CAAGGCCCAG GCGGAAGCGT TGGCCCTCCA GGCCAGCCTG 2400 2401 AGGAAGGAGC AGATGCGGAT CCAGTCGCTG GAGAAGACAG TGGAGCAGAA GACTAAAGAG 2460 2461 AACGAGGAGC TGACCAGGAT CTGCGACGAC CTCATCTCCA AGATGGAGAA GATCTGA 2517 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Pap-3308 | Pan paniscus | 99.64 | 0.0 | 1548 |
| LLPS-Hos-0505 | Homo sapiens | 98.81 | 0.0 | 1533 |
| LLPS-Gog-2439 | Gorilla gorilla | 96.3 | 0.0 | 1483 |
| LLPS-Poa-0990 | Pongo abelii | 93.08 | 0.0 | 1414 |
| LLPS-Mal-1265 | Mandrillus leucophaeus | 89.86 | 0.0 | 1342 |
| LLPS-Mam-0617 | Macaca mulatta | 89.5 | 0.0 | 1335 |
| LLPS-Maf-3615 | Macaca fascicularis | 89.5 | 0.0 | 1332 |
| LLPS-Man-1893 | Macaca nemestrina | 89.38 | 0.0 | 1332 |
| LLPS-Cea-3810 | Cercocebus atys | 89.26 | 0.0 | 1330 |
| LLPS-Paa-0817 | Papio anubis | 89.26 | 0.0 | 1335 |
| LLPS-Nol-1725 | Nomascus leucogenys | 88.94 | 0.0 | 1342 |
| LLPS-Rhb-2825 | Rhinopithecus bieti | 87.83 | 0.0 | 1298 |
| LLPS-Chs-0895 | Chlorocebus sabaeus | 87.09 | 0.0 | 1323 |
| LLPS-Aon-2693 | Aotus nancymaae | 78.76 | 0.0 | 1095 |
| LLPS-Loa-2737 | Loxodonta africana | 78.57 | 5e-149 | 459 |
| LLPS-Caj-3860 | Callithrix jacchus | 76.37 | 0.0 | 1105 |
| LLPS-Ran-4251 | Rattus norvegicus | 74.76 | 3e-40 | 161 |
| LLPS-Mea-2078 | Mesocricetus auratus | 70.24 | 8e-29 | 126 |
| LLPS-Mum-2109 | Mus musculus | 64.67 | 6e-126 | 399 |
| LLPS-Myl-3360 | Myotis lucifugus | 62.84 | 7e-49 | 175 |
| LLPS-Aim-0260 | Ailuropoda melanoleuca | 60.68 | 0.0 | 827 |
| LLPS-Urm-3492 | Ursus maritimus | 60.33 | 0.0 | 822 |
| LLPS-Eqc-0016 | Equus caballus | 59.98 | 0.0 | 818 |
| LLPS-Caf-3856 | Canis familiaris | 59.83 | 0.0 | 811 |
| LLPS-Pes-1558 | Pelodiscus sinensis | 59.43 | 9e-26 | 118 |
| LLPS-Otg-2713 | Otolemur garnettii | 59.02 | 0.0 | 802 |
| LLPS-Ict-1310 | Ictidomys tridecemlineatus | 58.94 | 0.0 | 758 |
| LLPS-Tut-0536 | Tursiops truncatus | 57.89 | 0.0 | 748 |
| LLPS-Fud-0290 | Fukomys damarensis | 57.87 | 0.0 | 758 |
| LLPS-Fia-0067 | Ficedula albicollis | 57.61 | 2e-23 | 110 |
| LLPS-Tag-1831 | Taeniopygia guttata | 57.61 | 9e-22 | 105 |
| LLPS-Asm-1768 | Astyanax mexicanus | 56.97 | 1e-48 | 177 |
| LLPS-Xet-0135 | Xenopus tropicalis | 56.84 | 2e-23 | 110 |
| LLPS-Mup-2149 | Mustela putorius furo | 56.8 | 0.0 | 743 |
| LLPS-Xim-2919 | Xiphophorus maculatus | 55.26 | 5e-52 | 202 |
| LLPS-Icp-4088 | Ictalurus punctatus | 54.81 | 3e-28 | 121 |
| LLPS-Scm-1862 | Scophthalmus maximus | 54.79 | 6e-52 | 202 |
| LLPS-Ten-0519 | Tetraodon nigroviridis | 54.76 | 4e-43 | 169 |
| LLPS-Pof-0780 | Poecilia formosa | 54.64 | 1e-48 | 189 |
| LLPS-Tar-1820 | Takifugu rubripes | 54.64 | 1e-48 | 189 |
| LLPS-Orn-1435 | Oreochromis niloticus | 54.4 | 6e-51 | 197 |
| LLPS-Gaga-1452 | Gallus gallus | 54.4 | 3e-50 | 185 |
| LLPS-Orl-2357 | Oryzias latipes | 53.89 | 5e-43 | 168 |
| LLPS-Meg-0129 | Meleagris gallopavo | 53.85 | 4e-49 | 186 |
| LLPS-Gaa-2501 | Gasterosteus aculeatus | 53.55 | 6e-48 | 184 |
| LLPS-Scf-1895 | Scleropages formosus | 52.91 | 2e-52 | 204 |
| LLPS-Orc-4184 | Oryctolagus cuniculus | 52.88 | 1e-53 | 205 |
| LLPS-Ova-1755 | Ovis aries | 52.45 | 7e-90 | 295 |
| LLPS-Anp-1109 | Anas platyrhynchos | 52.4 | 4e-53 | 204 |
| LLPS-Sah-2109 | Sarcophilus harrisii | 52.38 | 1e-51 | 199 |
| LLPS-Dar-3771 | Danio rerio | 52.33 | 1e-41 | 169 |
| LLPS-Leo-0827 | Lepisosteus oculatus | 52.17 | 2e-51 | 199 |
| LLPS-Fec-3216 | Felis catus | 51.92 | 6e-53 | 204 |
| LLPS-Cap-2725 | Cavia porcellus | 51.92 | 5e-53 | 204 |
| LLPS-Bot-2367 | Bos taurus | 51.92 | 2e-53 | 207 |
| LLPS-Cas-3327 | Carlito syrichta | 51.44 | 4e-52 | 201 |
| LLPS-Sus-1546 | Sus scrofa | 51.44 | 1e-51 | 199 |
| LLPS-Mod-1607 | Monodelphis domestica | 51.06 | 3e-44 | 178 |
| LLPS-Dio-2216 | Dipodomys ordii | 50.96 | 3e-50 | 195 |
| LLPS-Ere-0128 | Erinaceus europaeus | 50.71 | 2e-50 | 191 |
| LLPS-Lac-1621 | Latimeria chalumnae | 50.24 | 5e-48 | 187 |
| LLPS-Ora-1802 | Ornithorhynchus anatinus | 49.76 | 9e-49 | 189 |
| LLPS-Anc-0073 | Anolis carolinensis | 49.29 | 2e-48 | 188 |
| LLPS-Cii-2223 | Ciona intestinalis | 33.17 | 8e-21 | 102 |
| LLPS-Drm-0236 | Drosophila melanogaster | 28.95 | 1e-15 | 86.3 |