• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pap-4199
CHAF1B

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: CHAF1B
Ensembl Gene: ENSPPAG00000029854.1
Ensembl Protein: ENSPPAP00000013366.1
Organism: Pan paniscus
Taxa ID: 9597
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Chromatin, P-body, Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MKVITCEIAW  HNKEPVYSLD  FQHGMAGRIH  RLASAGVDTN  VRIWKVEKGP  DGKAIVEFLS  60
61    NLARHTKAVN  VVRFSPTGEI  LASGGDDAVI  LLWKVNDNKE  PEQIAFQDED  EAQLNKENWT  120
121   VVKTLRGHLE  DVYDICWATD  GNLMASASVD  NTAIIWDVSK  GQKISIFNEH  KSYVQGVTWD  180
181   PLGQYVATLS  CDRVLRVYSI  QKKRVAFNVS  KMLSGIGAEG  EARSYRMFHD  DSMKSFFRRL  240
241   SFTPDGSLLL  TPAGCVESGE  NVMNTTYVFS  RKNLKRPIAH  LPCPGKATLA  VRCCPVYFEL  300
301   RPVVETGVEL  MSLPYRLVFA  VASEDSVLLY  DTQQSFPFGY  VSNIHYHTLS  DISWSSDGAF  360
361   LAISSTDGYC  SFVTFEKDEL  GIPLKEKPVL  NMRTPDTAKK  TKSQTHRGSS  PGPRPVEGTP  420
421   ASRTQDPSSP  GTTPPQARQA  PAPTAIRDPP  SITPAVKSPL  PGPSEEKTLQ  PSSQNTKAHP  480
481   SRRVTLNTLQ  AWSKTTPRRI  NLTPLKTDTP  PSSVPTSVIS  TPSTEEIQSE  TPGDAQGSPP  540
541   ELKRPRLHEN  KGGTESLDP  559
Nucleotide CDS Sequence (FASTA)
1     ATGAAAGTCA  TCACTTGTGA  AATAGCCTGG  CACAACAAGG  AGCCCGTGTA  CAGCCTGGAC  60
61    TTCCAGCATG  GGATGGCTGG  GAGGATCCAC  AGACTGGCGT  CTGCCGGCGT  GGACACCAAT  120
121   GTCAGGATCT  GGAAGGTAGA  AAAGGGACCA  GATGGAAAAG  CCATCGTGGA  ATTTTTGTCC  180
181   AATCTTGCTC  GTCATACCAA  AGCCGTCAAT  GTTGTGCGTT  TTTCTCCAAC  TGGGGAAATT  240
241   TTAGCATCGG  GAGGAGATGA  TGCTGTCATC  CTGTTGTGGA  AGGTGAATGA  TAACAAGGAG  300
301   CCGGAGCAGA  TCGCTTTTCA  GGATGAGGAC  GAGGCCCAGC  TGAACAAGGA  GAACTGGACG  360
361   GTTGTGAAGA  CTCTGCGGGG  CCACTTAGAA  GATGTGTATG  ATATTTGCTG  GGCAACTGAT  420
421   GGGAATTTAA  TGGCTTCTGC  CTCTGTGGAT  AACACAGCCA  TCATATGGGA  TGTCAGCAAA  480
481   GGACAAAAGA  TATCAATTTT  TAATGAACAT  AAAAGTTATG  TCCAAGGAGT  AACCTGGGAC  540
541   CCTTTGGGTC  AATATGTTGC  TACTCTGAGC  TGTGACAGGG  TGCTGCGAGT  ATACAGTATA  600
601   CAGAAGAAGC  GTGTGGCTTT  CAATGTTTCG  AAGATGCTGT  CTGGAATAGG  GGCTGAAGGA  660
661   GAGGCAAGAA  GCTACCGGAT  GTTTCACGAC  GACAGCATGA  AGTCTTTCTT  CCGTAGACTG  720
721   AGTTTCACTC  CCGACGGATC  TTTGCTCCTC  ACGCCAGCTG  GATGTGTGGA  ATCTGGTGAA  780
781   AATGTAATGA  ATACCACTTA  TGTTTTCTCC  AGGAAGAATC  TTAAAAGGTA  TGCAGTCAAG  840
841   GAAATCCTTG  TTTCTGTGGT  TTTACGTTGT  CTCTGTCCCC  GACCCCCAGG  TGTGGAGCTG  900
901   ATGAGTCTGC  CCTACCGCCT  GGTGTTTGCT  GTGGCCTCGG  AGGACTCCGT  GCTTCTGTAT  960
961   GACACCCAGC  AGTCCTTCCC  TTTTGGTTAC  GTGTCTAATA  TACATTACCA  CACCCTCAGT  1020
1021  GACATTTCAT  GGTCCAGCGA  TGGTGCCTTC  CTGGCCATTT  CTTCCACGGA  CGGTTACTGC  1080
1081  TCATTTGTGA  CATTTGAGAA  AGATGAACTT  GGAATTCCTT  TGAAAGAGAA  GCCAGTTTTG  1140
1141  AACATGAGAA  CTCCTGATAC  AGCAAAGAAA  ACCAAGAGTC  AGACACATCG  AGGGTCTTCG  1200
1201  CCAGGACCCA  GACCGGTAGA  GGGAACCCCT  GCCAGCAGAA  CCCAAGACCC  CAGCAGCCCC  1260
1261  GGCACGACCC  CCCCTCAGGC  CAGACAGGCC  CCAGCCCCAA  CAGCCATCAG  GGACCCTCCC  1320
1321  TCCATCACTC  CTGCTGTCAA  AAGCCCCTTG  CCGGGGCCTT  CGGAGGAGAA  GACCCTGCAG  1380
1381  CCCAGTAGTC  AAAACACAAA  AGCCCACCCA  TCCCGGAGGG  TCACTCTGAA  CACACTGCAA  1440
1441  GCCTGGAGCA  AGACAACACC  ACGGAGAATA  AACTTAACAC  CCTTAAAGAC  AGACACTCCA  1500
1501  CCAAGTTCTG  TACCAACCAG  TGTGATTTCC  ACCCCTTCTA  CAGAAGAAAT  TCAGTCAGAG  1560
1561  ACGCCTGGAG  ACGCTCAGGG  CAGTCCCCCA  GAGCTAAAGC  GGCCCAGACT  CCATGAAAAC  1620
1621  AAAGGAGGCA  CGGAAAGTCT  GGACCCTTGA  1650

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pat-0727Pan troglodytes99.460.01075
LLPS-Hos-0131Homo sapiens99.460.01078
LLPS-Gog-0790Gorilla gorilla98.750.01070
LLPS-Nol-2262Nomascus leucogenys98.570.01068
LLPS-Poa-3476Pongo abelii98.210.01064
LLPS-Mal-0488Mandrillus leucophaeus98.070.0 921
LLPS-Maf-0972Macaca fascicularis98.030.01065
LLPS-Mam-2060Macaca mulatta98.030.01065
LLPS-Man-3676Macaca nemestrina98.030.01065
LLPS-Chs-1641Chlorocebus sabaeus97.670.01063
LLPS-Rhb-0843Rhinopithecus bieti97.040.0 876
LLPS-Cea-0726Cercocebus atys96.240.01040
LLPS-Orc-2436Oryctolagus cuniculus96.070.0 772
LLPS-Caj-0420Callithrix jacchus94.620.01024
LLPS-Paa-1561Papio anubis93.770.01001
LLPS-Cas-1579Carlito syrichta91.290.0 560
LLPS-Sus-2438Sus scrofa89.720.0 910
LLPS-Ict-0316Ictidomys tridecemlineatus88.870.0 979
LLPS-Otg-1931Otolemur garnettii88.710.0 974
LLPS-Eqc-2373Equus caballus88.380.0 982
LLPS-Loa-3096Loxodonta africana87.30.0 974
LLPS-Fud-3945Fukomys damarensis87.120.0 946
LLPS-Dio-0027Dipodomys ordii85.660.0 955
LLPS-Urm-0971Ursus maritimus85.560.0 949
LLPS-Caf-2742Canis familiaris84.560.0 936
LLPS-Bot-4625Bos taurus84.320.0 936
LLPS-Fec-0531Felis catus83.920.0 909
LLPS-Aim-2128Ailuropoda melanoleuca83.540.0 936
LLPS-Ran-2750Rattus norvegicus83.220.0 935
LLPS-Mum-1151Mus musculus82.690.0 916
LLPS-Mea-0214Mesocricetus auratus81.660.0 918
LLPS-Sah-0043Sarcophilus harrisii80.360.0 890
LLPS-Mod-2832Monodelphis domestica79.720.0 873
LLPS-Cap-2045Cavia porcellus78.140.0 800
LLPS-Myl-1187Myotis lucifugus77.840.0 862
LLPS-Meg-0396Meleagris gallopavo76.60.0 795
LLPS-Xet-2035Xenopus tropicalis75.570.0 700
LLPS-Pes-1189Pelodiscus sinensis74.910.0 825
LLPS-Tag-0149Taeniopygia guttata73.80.0 766
LLPS-Fia-0735Ficedula albicollis73.80.0 775
LLPS-Gaga-0740Gallus gallus73.360.0 800
LLPS-Aon-1144Aotus nancymaae72.990.0 697
LLPS-Anc-1546Anolis carolinensis72.220.0 782
LLPS-Leo-2651Lepisosteus oculatus69.120.0 711
LLPS-Orn-0542Oreochromis niloticus66.070.0 671
LLPS-Dar-1605Danio rerio65.310.0 683
LLPS-Xim-0223Xiphophorus maculatus65.160.0 669
LLPS-Pof-2157Poecilia formosa65.160.0 671
LLPS-Tar-1876Takifugu rubripes64.730.0 658
LLPS-Icp-1818Ictalurus punctatus64.690.0 669
LLPS-Gaa-0194Gasterosteus aculeatus64.670.0 659
LLPS-Asm-1433Astyanax mexicanus64.060.0 668
LLPS-Orl-3830Oryzias latipes63.620.0 665
LLPS-Ten-2507Tetraodon nigroviridis61.830.0 640
LLPS-Fuo-0253Fusarium oxysporum60.562e-1996.7
LLPS-Fus-0992Fusarium solani60.562e-1996.7
LLPS-Nec-1535Neurospora crassa58.91e-1997.4
LLPS-Blg-0806Blumeria graminis57.751e-1894.0
LLPS-Beb-1165Beauveria bassiana57.758e-1994.4
LLPS-Scf-3093Scleropages formosus57.140.0 654
LLPS-Dos-1253Dothistroma septosporum56.522e-1893.2
LLPS-Gag-0690Gaeumannomyces graminis56.349e-1994.4
LLPS-Map-0004Magnaporthe poae56.348e-1994.4
LLPS-Cogr-1427Colletotrichum graminicola54.933e-1892.4
LLPS-Lac-1518Latimeria chalumnae54.139e-178 519
LLPS-Asc-0635Aspergillus clavatus54.052e-1996.3
LLPS-Lem-1034Leptosphaeria maculans53.522e-1893.2
LLPS-Spr-1445Sporisorium reilianum52.333e-21 102
LLPS-Usm-1319Ustilago maydis51.165e-21 101
LLPS-Mao-1037Magnaporthe oryzae51.142e-1893.2
LLPS-Pyt-1424Pyrenophora teres50.72e-1893.2
LLPS-Pytr-1141Pyrenophora triticirepentis50.72e-1893.2
LLPS-Pug-0533Puccinia graminis50.01e-1997.4
LLPS-Cis-1641Ciona savignyi48.33e-39 145
LLPS-Zyt-1118Zymoseptoria tritici48.084e-2098.6
LLPS-Drm-1697Drosophila melanogaster47.831e-123 388
LLPS-Cii-0842Ciona intestinalis47.583e-127 389
LLPS-Trv-1048Trichoderma virens46.673e-1995.9
LLPS-Orp-1690Oryza punctata46.22e-40 160
LLPS-Asn-0310Aspergillus nidulans45.286e-46 176
LLPS-Cog-0576Colletotrichum gloeosporioides44.93e-1995.9
LLPS-Nef-1012Neosartorya fischeri44.652e-46 177
LLPS-Yal-0805Yarrowia lipolytica44.392e-40 159
LLPS-Ved-0695Verticillium dahliae43.42e-43 169
LLPS-Met-1871Medicago truncatula43.325e-101 324
LLPS-Sei-1705Setaria italica43.141e-95 307
LLPS-Thc-0803Theobroma cacao42.968e-100 318
LLPS-Zem-1551Zea mays42.962e-97 312
LLPS-Php-0436Physcomitrella patens42.585e-104 332
LLPS-Aso-0346Aspergillus oryzae42.525e-45 173
LLPS-Asf-0177Aspergillus flavus42.526e-45 173
LLPS-Coo-0580Colletotrichum orbiculare42.447e-42 164
LLPS-Orbr-1575Oryza brachyantha42.077e-95 305
LLPS-Brd-2148Brachypodium distachyon41.981e-101 323
LLPS-Hea-2549Helianthus annuus41.853e-97 310
LLPS-Gor-1116Gossypium raimondii41.752e-97 310
LLPS-Glm-0033Glycine max41.733e-107 340
LLPS-Asni-1506Aspergillus niger41.261e-42 166
LLPS-Orgl-1214Oryza glumaepatula41.061e-92 300
LLPS-Via-0137Vigna angularis41.061e-103 331
LLPS-Orni-1579Oryza nivara41.061e-92 300
LLPS-Orr-0740Oryza rufipogon41.061e-92 300
LLPS-Ors-0932Oryza sativa41.061e-92 300
LLPS-Sob-0255Sorghum bicolor41.034e-97 311
LLPS-Amt-0660Amborella trichopoda40.942e-97 311
LLPS-Viv-0097Vitis vinifera40.851e-96 308
LLPS-Hov-1971Hordeum vulgare40.816e-91 296
LLPS-Orm-0459Oryza meridionalis40.812e-91 296
LLPS-Nia-1715Nicotiana attenuata40.75e-96 306
LLPS-Trr-0803Trichoderma reesei40.659e-42 163
LLPS-Vir-0702Vigna radiata40.61e-102 322
LLPS-Lep-0814Leersia perrieri40.555e-93 301
LLPS-Tra-1945Triticum aestivum40.551e-92 299
LLPS-Tru-1193Triticum urartu40.552e-92 300
LLPS-Prp-1889Prunus persica40.444e-98 315
LLPS-Abg-0363Absidia glauca40.154e-88 284
LLPS-Brr-1674Brassica rapa40.14e-89 290
LLPS-Orb-1675Oryza barthii40.059e-87 284
LLPS-Cus-0458Cucumis sativus40.05e-96 308
LLPS-Sol-1676Solanum lycopersicum40.01e-94 303
LLPS-Brn-0890Brassica napus40.02e-93 301
LLPS-Phv-2052Phaseolus vulgaris40.06e-104 330
LLPS-Kop-1245Komagataella pastoris39.952e-94 300
LLPS-Mae-0599Manihot esculenta39.851e-94 303
LLPS-Bro-1293Brassica oleracea39.661e-92 300
LLPS-Coc-1368Corchorus capsularis39.61e-92 298
LLPS-Art-3097Arabidopsis thaliana39.567e-98 313
LLPS-Mua-2068Musa acuminata39.556e-92 296
LLPS-Osl-0488Ostreococcus lucimarinus39.553e-87 283
LLPS-Sot-1375Solanum tuberosum39.42e-90 292
LLPS-Arl-2600Arabidopsis lyrata39.383e-97 311
LLPS-Tum-1211Tuber melanosporum38.953e-100 321
LLPS-Pot-1987Populus trichocarpa37.552e-98 313
LLPS-Dac-1081Daucus carota37.522e-97 311
LLPS-Scj-0985Schizosaccharomyces japonicus37.477e-86 281
LLPS-Mel-0668Melampsora laricipopulina36.241e-51 187
LLPS-Ori-0051Oryza indica36.213e-67 233
LLPS-Asg-1075Ashbya gossypii35.483e-81 270
LLPS-Chc-0174Chondrus crispus35.413e-35 145
LLPS-Cae-1180Caenorhabditis elegans35.249e-66 228
LLPS-Crn-1141Cryptococcus neoformans34.482e-32 136
LLPS-Sac-1447Saccharomyces cerevisiae34.272e-81 269
LLPS-Scc-0560Schizosaccharomyces cryophilus33.544e-79 264
LLPS-Scp-0477Schizosaccharomyces pombe33.011e-83 276
LLPS-Cym-0727Cyanidioschyzon merolae31.793e-60 214
LLPS-Gas-0491Galdieria sulphuraria31.75e-62 224
LLPS-Mup-3995Mustela putorius furo29.582e-35 146
LLPS-Anp-1462Anas platyrhynchos29.461e-35 147
LLPS-Scm-0535Scophthalmus maximus28.611e-36 149
LLPS-Sem-1465Selaginella moellendorffii28.072e-39 158
LLPS-Asfu-0157Aspergillus fumigatus26.325e-35 145